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diferentes esquemas de HD<a class="elsevierStyleCrossRef" href="#bib0315"><span class="elsevierStyleSup">15</span></a>&#44; variaciones del sodio en el ba&#241;o<a class="elsevierStyleCrossRefs" href="#bib0320"><span class="elsevierStyleSup">16&#44;17</span></a>&#44; la dieta<a class="elsevierStyleCrossRef" href="#bib0325"><span class="elsevierStyleSup">17</span></a>&#44; y el aumento de duraci&#243;n o frecuencia de las sesiones<a class="elsevierStyleCrossRef" href="#bib0330"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">A pesar de que el MAPA podr&#237;a ser el m&#233;todo <span class="elsevierStyleItalic">gold standard</span> para diagn&#243;stico de HTA en pacientes en HD&#44; existen pocos estudios del mismo en este tipo de pacientes&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Los objetivos de nuestro trabajo han sido&#58; 1&#46; Conocer la TA en la sesi&#243;n de HD&#46; 2&#46; Estudiar la TA&#44; en el periodo interdial&#237;tico&#44; mediante MAPA de 44 horas&#46; 3&#46; Conocer la concordancia entre la TA en la sesi&#243;n de HD y MAPA&#46; 4&#46; Valorar los cambios de tratamiento despu&#233;s de la realizaci&#243;n del MAPA&#46; 5&#46; Realizar una BIS a todos los pacientes y en los hiperhidratados e hipertensos&#44; seg&#250;n MAPA&#44; valorar cambios en la TA despu&#233;s de ajustar el peso seco&#46; 6&#46; Conocer factores asociados a TAS y TAD promedio del MAPA&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material y m&#233;todos</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Poblaci&#243;n estudiada</span><p id="par0060" class="elsevierStylePara elsevierViewall">Estudio prospectivo observacional&#44; de los pacientes de nuestra unidad de hemodi&#225;lisis entre el 11&#47;02&#47;2016 hasta el 07&#47;03&#47;2019&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Los datos cl&#237;nicos&#44; demogr&#225;ficos&#44; de las sesiones de di&#225;lisis y anemia se extrajeron de las historias cl&#237;nicas informatizadas&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">El trabajo fue aprobado por el comit&#233; de &#233;tica del hospital&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Criterios de inclusi&#243;n</span><p id="par0075" class="elsevierStylePara elsevierViewall">Pacientes mayores de 18 a&#241;os&#44; estables&#44; que llevasen dializ&#225;ndose m&#225;s de tres meses y firmaran el consentimiento informado&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Criterios de exclusi&#243;n</span><p id="par0080" class="elsevierStylePara elsevierViewall">Los criterios de exclusi&#243;n fueron&#58; enfermedades card&#237;acas severas y&#47;o&#44; enfermedades intercurrentes en el mes previo a ser incluidos en el estudio&#44; consumo activo de drogas&#44; modificaci&#243;n del PS o f&#225;rmacos antihipertensivos en las dos semanas previas a la inclusi&#243;n&#44; negativa del paciente a firmar el consentimiento informado&#44; no hablar espa&#241;ol&#44; presentar d&#233;ficit cognitivo&#44; registro incorrecto del MAPA e imposibilidad de realizar BIS por alguno de los siguientes motivos&#58; portadores de&#58; desfibriladores&#44; marcapasos&#44; stents&#44; material de sutura met&#225;lico en el coraz&#243;n o arterias principales o&#44; pr&#243;tesis met&#225;licas&#46;</p></span><span id="sec0115" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Definici&#243;n de HTA y mediciones de las tensiones arteriales&#58;</span><span id="sec0120" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Sesi&#243;n de HD</span><p id="par0090" class="elsevierStylePara elsevierViewall">Todos los pacientes se dializaban tres veces a la semana&#44; con dializadores de polisulfona de alto flujo&#44; bicarbonato en el ba&#241;o de 35 mEq&#47;l y conductividad de sodio de 138 mili siemens&#47;cm &#40;mS&#47;cm&#41;&#44; 17 de ellos con modalidad <span class="elsevierStyleItalic">on line</span> y el resto HD est&#225;ndar&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Las tensiones arteriales previas&#44; y posteriores a las sesiones de HD&#44; fueron recogidas mediante monitor de Fresenius 5008&#44; durante dos semanas&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">La TA pre-HD se recoge previo a puncionar el acceso o conectar el cat&#233;ter&#44; en el brazo opuesto a la fistula y despu&#233;s de estar el paciente 5 minutos en posici&#243;n supina&#46; La post-HD luego de desconectar al paciente y coagular en caso que sean f&#237;stulas&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Se defini&#243; HTA&#44; seg&#250;n criterio de las gu&#237;as KDOQI del 2005&#58; TA pre-HD mayor de 140&#47;90 mmHg&#44; post-HD de 130&#47;80 mmHg o pacientes que precisen utilizar f&#225;rmacos antihipertensivos&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">MAPA</span><p id="par0115" class="elsevierStylePara elsevierViewall">Para las mediciones mediante MAPA&#44; se utiliz&#243; el dispositivo&#58; Custo Screen 300&#44; validado por la ESH &#40;<span class="elsevierStyleItalic">European Society of Hypertension</span>&#44; 2010&#41;&#46; Colocamos el mismo a mitad de semana&#44; durante 44 horas&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Las mediciones comienzan inmediatamente al finalizar la sesi&#243;n de HD y terminan previo a comenzar la siguiente sesi&#243;n&#59; programadas cada 30 minutos durante el per&#237;odo diurno &#40;06&#58;00 a 22&#58;00 horas&#41; y cada hora por la noche &#40;22&#58;00 a 06&#58;00 horas&#41;&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Se consider&#243; un registro v&#225;lido aquel que tuviese al menos 36 horas de monitorizaci&#243;n&#44; 60 registros y menos del 10&#37; del total de las mediciones err&#243;neas&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Extrapolando los valores de la poblaci&#243;n general&#44; definimos HTA con cifras de TA&#58; diurna &#62; 135&#47;85 mmHg&#44; nocturna &#62; 120&#47;70 mmHg y promedio &#62; 130&#47;80 mmHg&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Para definir si un paciente es <span class="elsevierStyleItalic">dipper</span> o no&#44; utilizamos el descenso de la TAS promedio de las dos noches de recogida&#44; ya que esta es la que asocia m&#225;s con el pron&#243;stico de la HTA&#44; siendo <span class="elsevierStyleItalic">dipper</span> aquellos con un descenso de entre 10 y 20&#37;&#44; no <span class="elsevierStyleItalic">dipper</span> menor del &#60; 10&#37; y <span class="elsevierStyleItalic">riser</span> aquellos que aumentan la tensi&#243;n durante la noche&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">Para la realizaci&#243;n del segundo MAPA en aquellos pacientes hiperhidratados&#44; utilizamos para definir HTA las cifras de TAS promedio mayor de 130 mmHg&#44; por ser la TAS la que m&#225;s se asocia a morbimortalidad&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Mediciones de bioimpedancia&#58;</span><p id="par0145" class="elsevierStylePara elsevierViewall">Para el estudio de la composici&#243;n corporal se utiliz&#243; BIS de Fresenius Medical Care &#40;BCM&#174;&#41;&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">La medici&#243;n se ha realizado posteriormente a la realizaci&#243;n del MAPA&#44; previo a comenzar la sesi&#243;n de di&#225;lisis&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Se consider&#243; hipertensi&#243;n dependiente de volumen cuando en la BCM los pacientes ten&#237;an una OH superior a dos litros&#44; criterio similar al publicado por otros autores &#40;Vega et al&#46;&#41;&#44; en el estudio de sobrehidrataci&#243;n en los pacientes en di&#225;lisis<a class="elsevierStyleCrossRef" href="#bib0335"><span class="elsevierStyleSup">19</span></a>&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Variables analizadas en relaci&#243;n con TA</span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Variables relacionadas con los pacientes</span><p id="par0160" class="elsevierStylePara elsevierViewall">Edad&#44; sexo&#44; IMC&#44; diabetes mellitus &#40;DM&#41;&#44; tiempo en hemodi&#225;lisis &#40;meses&#41;&#44; diuresis residual e &#237;ndice de comorbilidad de Charlson &#40;sin edad&#41;&#44; n&#250;mero de f&#225;rmacos antihipertensivos&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Variables relacionadas con la di&#225;lisis</span><p id="par0165" class="elsevierStylePara elsevierViewall">Calcio del ba&#241;o &#40;2&#44;5 vs&#46; 3 mEq&#47;l&#41;&#44; tasa de ultrafiltraci&#243;n &#40;ml&#47;h&#41; y ganancia de peso interdi&#225;lisis y tipo de acceso vascular &#40;cat&#233;ter tunelizado&#44; f&#237;stula nativa&#44; f&#237;stula prot&#233;sica&#41;&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Mediciones par&#225;metros de anemia</span><p id="par0170" class="elsevierStylePara elsevierViewall">Se calcul&#243;&#58; la hemoglobina promedio de los &#250;ltimos tres meses &#40;g&#47;dL&#41; previos a la colocaci&#243;n del MAPA&#44; el &#237;ndice de resistencia a la eritropoyetina &#40;dosis de eritropoyetina semanal&#47;peso&#47;hemoglobina&#41; y la dosis de eritropoyetina promedio de las &#250;ltimas seis sesiones expresadas como&#58; UI&#47;kg&#47;semana&#46;</p></span></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">An&#225;lisis estad&#237;stico</span><p id="par0175" class="elsevierStylePara elsevierViewall">Para describir la distribuci&#243;n de las variables cuantitativas se presentan media y desviaci&#243;n t&#237;pica o mediana y rango intercuart&#237;lico&#44; seg&#250;n la distribuci&#243;n de los datos&#44; y para describir la distribuci&#243;n de las variables cualitativas se presentan frecuencias absolutas y relativas&#46;</p><p id="par0180" class="elsevierStylePara elsevierViewall">Para el estudio de la concordancia entre t&#233;cnicas de medici&#243;n de las tensiones&#44; se estim&#243; el coeficiente de correlaci&#243;n intraclase mediante un modelo de efectos mixtos y considerando concordancia absoluta&#46; Se interpreta como mala o nula un valor &#60; 0&#44;3&#44; como mediocre un valor entre 0&#44;31 y 0&#44;50&#44; como moderado un valor entre 0&#44;51 y 0&#44;70&#44; buena un valor entre 0&#44;71 y 0&#44;90 y muy buena &#62; 0&#44;90&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">Para analizar el cambio en los valores de la TA&#44; antes y despu&#233;s de la bioimpedancia &#40;BIA&#41;&#44; se calcul&#243; el test de Wilcoxon&#44; test de hip&#243;tesis no param&#233;trico para medidas repetidas&#46;</p><p id="par0190" class="elsevierStylePara elsevierViewall">Para analizar factores asociados a los valores de TA&#44; se realiz&#243; un an&#225;lisis univariante comparando la distribuci&#243;n de las tensiones por grupos mediante el test <span class="elsevierStyleItalic">t</span> de Student o el an&#225;lisis de la varianza de un factor&#44; en el caso de variables centradas y aproximadamente normales&#44; o mediante los test no param&#233;tricos&#44; U de Mann-Whitney o el test de Kruskal-Wallis&#44; en otro caso&#46; En el caso de las variables cualitativas se calcul&#243; el test &#967;<span class="elsevierStyleSup">2</span> de Pearson&#44; el test exacto de Fisher&#46; Posteriormente&#44; con las variables estad&#237;sticamente significativas y&#47;o cl&#237;nicamente relevantes se ajust&#243; un modelo multivariante de regresi&#243;n lineal&#46;</p><p id="par0195" class="elsevierStylePara elsevierViewall">Todos los test se consideran bilaterales y como estad&#237;sticamente significativos aquellos p-valores menores de 0&#44;05&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Para el an&#225;lisis estad&#237;stico se emple&#243; el software SPSS 17&#46;</p></span></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">RESULTADOS</span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Caracter&#237;sticas generales</span><p id="par0205" class="elsevierStylePara elsevierViewall">Entre febrero del 2016 y marzo del 2019&#44; se reclutaron 150 pacientes para realizar MAPA de 44 horas&#44; 12 se negaron a usar el MAPA&#44; 35 presentaron criterios de exclusi&#243;n&#44; tres presentaron mediciones insuficientes&#44; quedando 100 pacientes para ser analizados&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">Las caracter&#237;sticas cl&#237;nicas&#44; demogr&#225;ficas&#44; datos de las sesiones de di&#225;lisis&#44; anemia y tratamiento se exponen en la <a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0215" class="elsevierStylePara elsevierViewall">Todos los pacientes llevaban m&#225;s de tres meses en hemodi&#225;lisis&#44; ten&#237;an tres sesiones semanales con duraci&#243;n media de las sesiones de 222 minutos &#43;&#47;- 17&#44;58 y con ganancias medias de peso entre sesiones de 1&#44;88 &#43;&#47;- 0&#44;83 kg&#44; 60 de ellos presentaban diuresis residual &#40;&#62; de 250 mL&#47;24 h&#41;&#44; 51&#37; con f&#237;stulas nativas&#44; 12&#37; con prot&#233;sicas y 37&#37; con cat&#233;ter tunelizado&#46;</p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">TA durante la sesi&#243;n de hemodi&#225;lisis</span><p id="par0220" class="elsevierStylePara elsevierViewall">Las medias de la TAS y TAD pre-HD fueron 146&#44;98 &#43;&#47;- 15&#44;37 y 69&#44;92 &#43;&#47;- 12&#44;61 mmHg&#46; Las medias de TAS y TAD post-HD fueron&#58; 140&#44;3 &#43;&#47;- 17&#44;31 y 70&#44;64 &#43;&#47;- 10&#44;88 mmHg&#46; La <a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a> muestra el porcentaje de pacientes&#44; hipertensos pre-HD y post-HD&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">TA mediante MAPA</span><p id="par0225" class="elsevierStylePara elsevierViewall">El promedio de duraci&#243;n de los MAPAS fue de 43&#44;57 &#43;&#47;- 5&#44;76 horas&#44; y el n&#250;mero de mediciones media de 74&#44;66 &#43;&#47;- 8&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall">Las medias de TAS y TAD diurnas fueron&#58; 140&#44;95 &#43;&#47;- 18&#44;5 y 81&#44;64 &#43;&#47;- 11 mmHg&#44; las nocturnas 139 &#43;&#47;- 21&#44;97 y 78&#44;2 &#43;&#47;- 12&#44;61 mmHg y las promedio&#58; 140 &#43;&#47;- 19&#44;29 y 80&#44;12 &#43;&#47;- 11&#44;31 mmHg&#46; 65&#37; tuvieron una TA diurna &#62; 135&#47;85 mmHg&#44; 90&#37; TA nocturna &#62; 120&#47;70 mmHg y 76&#37; una TA promedio &#62; 130&#47;80 mmHg &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">tabla 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0235" class="elsevierStylePara elsevierViewall">Las TAS y TAD promedio fueron 4&#44;7 mmHg &#40;3&#44;8&#37;&#41; y 1&#44;1 mmHg &#40;1&#44;64&#37;&#41; m&#225;s altas el segundo d&#237;a&#46;</p><p id="par0240" class="elsevierStylePara elsevierViewall">S&#243;lo un 11&#37; de la poblaci&#243;n estudiada present&#243; un patr&#243;n <span class="elsevierStyleItalic">dipper</span>&#44; 51&#37; fueron no <span class="elsevierStyleItalic">dipper</span> y 38&#37; <span class="elsevierStyleItalic">riser</span>&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0155">Concordancia entre tensiones de las sesiones y del MAPA</span><p id="par0245" class="elsevierStylePara elsevierViewall">La <a class="elsevierStyleCrossRef" href="#tbl0020">tabla 4</a> muestra que la concordancia entre las TAS pre-HD y las del MAPA son moderadas&#44; mientras que la que hay entre las TAS post-HD y las recogidas mediante MAPA son mediocres&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0250" class="elsevierStylePara elsevierViewall">La <a class="elsevierStyleCrossRef" href="#tbl0025">tabla 5</a> muestra que la concordancia entre las TAD pre-HD son buenas para la diurna y promedio del MAPA y moderadas para la nocturna&#44; mientras que las que hay entra la TAD post-HD y el MAPA son moderadas&#46;</p><elsevierMultimedia ident="tbl0025"></elsevierMultimedia><p id="par0255" class="elsevierStylePara elsevierViewall">La TAS post-HD es la que peor concordancia ha presentado con el MAPA&#46; Por el contrario&#44; la TAD pre-HD es la que mejor concordancia ha presentado&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0160">F&#225;rmacos antihipertensivos y MAPA</span><p id="par0260" class="elsevierStylePara elsevierViewall">La <a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a> muestra la distribuci&#243;n de los f&#225;rmacos antihipertensivos&#46;</p><p id="par0265" class="elsevierStylePara elsevierViewall">El 89&#37; de los pacientes recib&#237;a al menos un antihipertensivo&#44; un 52&#37; recib&#237;an tres o m&#225;s&#46; El grupo m&#225;s utilizado fue el de antagonistas c&#225;lcicos con 65&#37; de los pacientes&#46;</p><p id="par0270" class="elsevierStylePara elsevierViewall">Despu&#233;s de valorar los resultados de las tensiones del MAPA&#59; 6&#37; precis&#243; bajar la dosis de los f&#225;rmacos&#44; 28&#37; subirla&#44; 9&#37; suspenderlos&#44; y 17&#37; a&#241;adir uno nuevo&#46;</p></span><span id="sec0095" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0165">Hiperhidrataci&#243;n y BIS</span><p id="par0275" class="elsevierStylePara elsevierViewall">Despu&#233;s de realizar las bioimpedancias&#44; el 61&#37; de pacientes no necesit&#243; ajuste&#44; 32&#37; se baj&#243; el PS y en el 7&#37; se subi&#243;&#46;</p><p id="par0280" class="elsevierStylePara elsevierViewall">De 32 pacientes que estaban hiperhidratados&#44; seis eran normotensos&#44; seg&#250;n TAS promedio del MAPA&#46; De los 26 restantes &#40;hiperhidratados e hipertensos&#44; seg&#250;n TAS promedio del MAPA &#8805; de 130 mmHg&#41;&#58; a cuatro no se les pudo bajar PS por intolerancia hemodin&#225;mica&#44; cuatro se negaron a colocaci&#243;n nuevamente del MAPA y cuatro requirieron ingresos hospitalarios&#44; quedando finalmente 14 pacientes hiperhidratados e hipertensos a los que se les pudo bajar PS y realizar segundo MAPA y BIS&#46;</p><p id="par0285" class="elsevierStylePara elsevierViewall">La <a class="elsevierStyleCrossRef" href="#tbl0030">tabla 6</a> muestra a los pacientes a los que se baj&#243; el PS&#44; observ&#225;ndose un descenso estad&#237;sticamente significativo en todas las cifras de tensi&#243;n arterial&#44; siendo la TAD nocturna la de mayor descenso 10&#44;36&#37; &#40;&#43;&#47;- 9&#44;94&#41; y la TAD promedio la de menor descenso 7&#44;04&#37; &#40;&#43;&#47;- 7&#44;97&#41;&#46;</p><elsevierMultimedia ident="tbl0030"></elsevierMultimedia><p id="par0290" class="elsevierStylePara elsevierViewall">Los cambios de par&#225;metros entre las primeras y segundas bioimpedancias fueron todas significativas&#44; excepto para el ICW &#40;<a class="elsevierStyleCrossRef" href="#tbl0035">tabla 7</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0035"></elsevierMultimedia></span><span id="sec0100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0170">Factores asociados a TA del MAPA</span><span id="sec0105" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0175">TAS promedio</span><p id="par0295" class="elsevierStylePara elsevierViewall">Variables relacionadas con los pacientes&#58;</p><p id="par0300" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Sexo</span>&#58; Mujeres 143&#44;59 &#43;&#47;- 19&#44;20 vs&#46; 137&#44;82 &#43;&#47;- 19&#44;17 mmHg en hombres &#40;P&#58; 0&#44;14&#41;&#46;</p><p id="par0305" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Diabetes&#58;</span> No diab&#233;ticos 138&#44;12 &#43;&#47;- 19 vs&#46; 142&#44;10 &#43;&#47;- 19&#44;49 mmHg en diab&#233;ticos &#40;P&#58; 0&#44;30&#41;&#46;</p><p id="par0310" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">F&#225;rmacos antihipertensivos</span>&#58; Existe una correlaci&#243;n positiva significativa entre n&#250;mero de f&#225;rmacos y TAS &#40;<a class="elsevierStyleCrossRef" href="#tbl0040">tabla 8</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0040"></elsevierMultimedia><p id="par0315" class="elsevierStylePara elsevierViewall">El resto de variables relacionadas con los pacientes se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0040">tabla 8</a>&#46;</p><p id="par0320" class="elsevierStylePara elsevierViewall">Variables relacionadas con la di&#225;lisis&#58;</p><p id="par0325" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Calcio del ba&#241;o</span>&#58; Calcio 3 mEq&#47;l 143&#44; 78 &#43;&#47;- 19 mmHg vs&#46; 136&#44;36 &#43;&#47;- 19 mmHg para calcio de 2&#44;5 mEq&#47;l &#40;P&#58; 0&#44;050&#41;&#46;</p><p id="par0330" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Acceso vascular&#58;</span> Pacientes portadores de cat&#233;teres tunelizados 141&#44;78 &#43;&#47;- 19&#44;21 mmHg&#44; f&#237;stulas nativas 137&#44;67 &#43;&#47;- 18&#44;70 mm&#47;Hg y en f&#237;stulas prot&#233;sicas 145 &#43;&#47;-22&#44;10 mmHg &#40;P&#58;0&#44;397&#41;&#46;</p><p id="par0335" class="elsevierStylePara elsevierViewall">El resto de variables relacionadas con la di&#225;lisis se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0040">tabla 8</a>&#46;</p><p id="par0340" class="elsevierStylePara elsevierViewall">Variables relacionadas con anemia&#58;</p><p id="par0345" class="elsevierStylePara elsevierViewall">Hay una correlaci&#243;n positiva baja significativa entre las dosis de EPO y TAS promedio&#44; no existiendo correlaciones significativas&#44; ni con las cifras de hemoglobina ni con &#237;ndice de resistencia a la EPO &#40;<a class="elsevierStyleCrossRef" href="#tbl0040">tabla 8</a>&#41;&#46;</p><p id="par0350" class="elsevierStylePara elsevierViewall">El estudio de regresi&#243;n lineal confirm&#243; como variables significativas asociadas a la TAS la EPO &#40;p &#60; 0&#44;01&#41; y el n&#250;mero de f&#225;rmacos antihipertensivos &#40;p &#60; 0&#44;01&#41;&#46;</p><p id="par0355" class="elsevierStylePara elsevierViewall">TAD promedio&#58;</p><p id="par0360" class="elsevierStylePara elsevierViewall">Variables relacionadas con los pacientes&#58;</p><p id="par0365" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Sexo&#58;</span> Mujeres 82&#44;38 &#43;&#47;- 10&#44;64 y en hombres 78&#44;67 &#43;&#47;- 11&#44;57 mmHg &#40;P&#58; 0&#44;11&#41;&#46;</p><p id="par0370" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Diabetes&#58;</span> No diab&#233;ticos 82&#44;9 &#43;&#47;-10&#44;88 y en diab&#233;ticos 77&#44;22 &#43;&#47;-11&#44;13 mmHg &#40;P&#58; 0&#44;011&#41;&#46;</p><p id="par0375" class="elsevierStylePara elsevierViewall">La edad&#44; IMC&#44; &#237;ndice de comorbilidad de Charlson y diuresis presentaron un correlaci&#243;n negativa significativa con la TAD promedio&#46;</p><p id="par0380" class="elsevierStylePara elsevierViewall">El resto de las variables relacionadas con los pacientes se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0045">tabla 9</a>&#46;</p><elsevierMultimedia ident="tbl0045"></elsevierMultimedia><p id="par0385" class="elsevierStylePara elsevierViewall">Variables relacionadas con la di&#225;lisis&#58;</p><p id="par0390" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Calcio del ba&#241;o&#58;</span> Calcio igual a 3 mEq&#47;l 81&#44;22 &#43;&#47;- 11&#44;58 mmHg vs&#46; 79&#44;02 &#43;&#47;-11&#44;048 mm con ba&#241;o de 2&#44;5 mEq&#47;l &#40;P&#58; 0&#44;33&#41;&#46;</p><p id="par0395" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Acceso vascular&#58;</span> Pacientes portadores de cat&#233;teres tunelizados 79&#44;97 &#43;&#47;- 11&#44;02 mmHg&#44; f&#237;stulas nativas&#58; 80&#44;29 &#43;&#47;- 11&#44;40 mmHg y f&#237;stulas prot&#233;sicas 79&#44;83 &#43;&#47;- 12&#44;75 mmHg &#40;P&#58; 0&#44;98&#41;&#46;</p><p id="par0400" class="elsevierStylePara elsevierViewall">El resto de variables relacionadas con la di&#225;lisis se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0045">tabla 9</a>&#46;</p><p id="par0405" class="elsevierStylePara elsevierViewall">Variables relacionadas con anemia&#58;</p><p id="par0410" class="elsevierStylePara elsevierViewall">Como muestra la <a class="elsevierStyleCrossRef" href="#tbl0045">tabla 9</a>&#44; la dosis de EPO present&#243; una correlaci&#243;n positiva significativa baja con la TAD promedio&#46; No as&#237; las cifras de hemoglobina ni el &#237;ndice de resistencia de la EPO&#46;</p><p id="par0415" class="elsevierStylePara elsevierViewall">El estudio de regresi&#243;n lineal ajustado por todas las variables significativas en el estudio univariante mostr&#243; como variables significativas asociadas a TAD promedio la edad &#40;p &#60; 0&#44;005&#41;&#44; IMC &#40;p &#60; 0&#44;03&#41; y EPO &#40;p &#60; 0&#44;03&#41;&#46;</p></span></span></span><span id="sec0110" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0180">Discusi&#243;n</span><p id="par0420" class="elsevierStylePara elsevierViewall">La prevalencia de HTA en los enfermos renales es muy elevada<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">2&#44;4-8</span></a>&#46; Existe&#44; adem&#225;s&#44; una gran variabilidad de la TA en estos pacientes&#46; La mayor&#237;a de ellos&#44; excepto una minor&#237;a del 5-15&#37;&#44; presenta una disminuci&#243;n de la TA sobre el final de las sesiones&#44; por el contrario&#44; durante el per&#237;odo interdi&#225;lisis la mayor&#237;a presenta un aumento progresivo de la misma<a class="elsevierStyleCrossRefs" href="#bib0295"><span class="elsevierStyleSup">11&#44;20</span></a>&#46; Por estos motivos&#44; muchos autores sugieren que el MAPA en pacientes en HD ser&#237;a el m&#233;todo <span class="elsevierStyleItalic">gold standard</span> para diagn&#243;stico de HTA<a class="elsevierStyleCrossRefs" href="#bib0245"><span class="elsevierStyleSup">1&#44;21</span></a>&#46; Sin embargo&#44; se han realizado muy pocos estudios sobre MAPA en pacientes en HD&#46;</p><p id="par0425" class="elsevierStylePara elsevierViewall">Nuestro estudio muestra esa gran variabilidad&#44; ya que si tomamos como referencia las cifras de TA durante la sesi&#243;n de HD&#44; todos los pacientes cumplen en alg&#250;n momento alg&#250;n criterio de HTA &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a>&#41;&#44; y sin embargo&#44; si nos basamos en el MAPA de 44 horas&#44; el 65&#37; de pacientes son hipertensos en la toma diurna&#44; el 90&#37; en la nocturna y un 76&#37; en la TA promedio &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">tabla 3</a>&#41;&#46; Otros datos de inter&#233;s es el alto porcentaje de pacientes con patr&#243;n patol&#243;gico nocturno&#44; 51&#37; no <span class="elsevierStyleItalic">dipper</span> y 38&#37; <span class="elsevierStyleItalic">riser</span>&#44; datos similares a otras publicaciones<a class="elsevierStyleCrossRefs" href="#bib0275"><span class="elsevierStyleSup">7&#44;22</span></a>&#46; Este patr&#243;n se asocia a&#58; hipertrofia ventricular izquierda&#44; morbimortalidad de causa cardiovascular y por todas las causas y lesi&#243;n de &#243;rgano diana&#44; por lo que es importante conocer su existencia e intentar revertirlo<a class="elsevierStyleCrossRefs" href="#bib0350"><span class="elsevierStyleSup">22-27</span></a>&#46; Estos problemas diagn&#243;sticos y de pron&#243;stico que surgen con las mediciones durante las sesiones han conducido a la publicaci&#243;n de dos documentos&#44; uno de la Sociedad Americana de Hipertensi&#243;n y Sociedad Americana de Nefrolog&#237;a<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">1</span></a>&#59; y el otro del grupo EURECA &#40;<span class="elsevierStyleItalic">European Cardiovascular and Renal Medicine</span>&#41; de la Asociaci&#243;n Europea Renal y Sociedad Europea de Di&#225;lisis y Trasplante &#40;ERA-EDTA&#41;&#44; que sugieren utilizar el MAPA de 44 horas para el diagn&#243;stico y manejo de la HTA en enfermos en di&#225;lisis<a class="elsevierStyleCrossRef" href="#bib0365"><span class="elsevierStyleSup">25</span></a>&#46;</p><p id="par0430" class="elsevierStylePara elsevierViewall">Sin embargo&#44; en el manejo cl&#237;nico diario&#44; as&#237; como en los estudios epidemiol&#243;gicos de HTA en pacientes en hemodi&#225;lisis&#44; se utilizan habitualmente las mediciones realizadas en las unidades de di&#225;lisis&#44; aunque estas no reflejen lo ocurrido en el per&#237;odo interdial&#237;tico&#44; y adem&#225;s su exactitud no ha sido bien establecida<a class="elsevierStyleCrossRefs" href="#bib0305"><span class="elsevierStyleSup">13&#44;28&#44;29</span></a>&#46; Creemos que es importante conocer&#44; a la hora de tomar decisiones&#44; hasta qu&#233; punto las tomas de TA realizadas durante la sesi&#243;n de HD se corresponden con cifras de TA del MAPA&#46; Hay estudios que han encontrado una pobre concordancia entre las tensiones recogidas en las sesiones de HD y aquellas mediante MAPA<a class="elsevierStyleCrossRefs" href="#bib0310"><span class="elsevierStyleSup">14&#44;28&#44;29</span></a>&#46; Otros estudios encontraron que la TA pre-HD ser&#237;a m&#225;s importante<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">30</span></a>&#44; otros que las mediciones post-HD<a class="elsevierStyleCrossRef" href="#bib0395"><span class="elsevierStyleSup">31</span></a>&#44; algunos la combinaci&#243;n de ambas<a class="elsevierStyleCrossRef" href="#bib0400"><span class="elsevierStyleSup">32</span></a> y otros aquellos valores recogidos a los 20 minutos de finalizar las sesiones<a class="elsevierStyleCrossRef" href="#bib0405"><span class="elsevierStyleSup">33</span></a>&#46; En nuestro trabajo&#44; la TAS pre-HD presenta una concordancia moderada con las del MAPA&#44; mientras que la TAD pre-HD muestra una buena concordancia con las tomas diurnas y promedio del MAPA y moderada con la nocturna&#44; datos que coinciden con los de Conlon et al&#46;<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">30</span></a>&#44; mientras que la TAS post-HD presenta una pobre correlaci&#243;n con el MAPA y la TAD post-HD muestra una concordancia moderada&#46; En resumen&#44; nuestro estudio muestra que la TAD predi&#225;lisis es la que mejor concordancia presenta con el MAPA&#46;</p><p id="par0435" class="elsevierStylePara elsevierViewall">La utilizaci&#243;n de la BIS para manejo de fluidos en pacientes en HD es una herramienta &#250;til para el ajuste del peso seco y de la volemia y&#44; por tanto&#44; para manejar la TA<a class="elsevierStyleCrossRef" href="#bib0410"><span class="elsevierStyleSup">34</span></a>&#46; Estudios observacionales demuestran que la reducci&#243;n de la volemia se asocia a disminuci&#243;n de la TA en el 70 a 90&#37; de los mismos<a class="elsevierStyleCrossRefs" href="#bib0270"><span class="elsevierStyleSup">6&#44;35&#44;36</span></a>&#46; Bas&#225;ndonos en estos datos&#44; en nuestro trabajo&#44; al disminuir el peso seco a un 32&#37; de pacientes hiperhidratados e hipertensos&#44; hubo un descenso significativo en todas las cifras de TA recogidas mediante MAPA&#44; siendo la TAD nocturna la de mayor descenso &#40;10&#44;36&#37;&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0030">tabla 6</a>&#41; y de todos los par&#225;metros de la BIS&#44; excepto el ICW&#46; Esto se deber&#237;a a que esta &#250;ltima no se modifica con la di&#225;lisis&#44; durante la cual extraemos al paciente un ultrafiltrado del plasma&#44; que es agua extracelular&#46; La intracelular est&#225; fundamentalmente en el m&#250;sculo y no se extrae&#46;</p><p id="par0440" class="elsevierStylePara elsevierViewall">En nuestro estudio tambi&#233;n hemos analizado que posibles variables est&#225;n relacionadas con las tensiones promedio del MAPA&#44; obteniendo que&#44; mediante estudio univariante&#44; la TAS promedio fue m&#225;s alta en pacientes con calcio m&#225;s alto del ba&#241;o&#44; mayor cantidad de f&#225;rmacos antihipertensivos y mayores dosis de EPO&#44; y en el estudio de regresi&#243;n permanecieron significativos el n&#250;mero de f&#225;rmacos antihipertensivos y la dosis de EPO&#46; Al analizar la TAD promedio&#44; el estudio univariante muestra una TAD m&#225;s elevada de forma significativa en pacientes m&#225;s j&#243;venes&#44; con menor diuresis&#44; Charlson m&#225;s bajos&#44; menor IMC&#44; no DM y mayores dosis de EPO&#46; El estudio de regresi&#243;n confirma la edad del paciente&#44; IMC y EPO como variables asociadas a una mayor TAD&#46; Vamos analizar estas variables&#58;</p><p id="par0445" class="elsevierStylePara elsevierViewall">F&#225;rmacos antihipertensivos&#58; Nuestro estudio muestra que a mayor n&#250;mero de f&#225;rmacos antihipertensivos&#44; mayor es la TAS promedio aunque no la TAD&#46; Agarwal<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">6</span></a> demostr&#243; una asociaci&#243;n entre un mayor uso de f&#225;rmacos antihipertensivos y falta de control de TA promedio del MAPA y tensiones post-HD&#46; Esta asociaci&#243;n probablemente muestre un mal control de la TA&#44; y como consecuencia de ello&#44; el m&#233;dico suba los antihipertensivos&#46;</p><p id="par0450" class="elsevierStylePara elsevierViewall">Edad&#58; En nuestro estudio&#44; a mayor edad menor TAD&#46; Esta menor TAD se podr&#237;a explicar como consecuencia de que al envejecer hay unas resistencias perif&#233;ricas m&#225;s bajas&#44; tal como indica el trabajo de Protogerou et al&#46;<a class="elsevierStyleCrossRef" href="#bib0425"><span class="elsevierStyleSup">37</span></a></p><p id="par0455" class="elsevierStylePara elsevierViewall">Calcio en ba&#241;o&#58; El efecto de la concentraci&#243;n de calcio del ba&#241;o sobre la TA estar&#237;a principalmente mediada por&#58; cambios en la contractilidad mioc&#225;rdica y en la reactividad vascular<a class="elsevierStyleCrossRefs" href="#bib0430"><span class="elsevierStyleSup">38&#44;39</span></a>&#46; En nuestro trabajo observamos tensiones arteriales sist&#243;licas promedio 7&#44;4 mmHg m&#225;s alta en pacientes con calcio del ba&#241;o de 3 mEq&#47;l&#46; Si bien existen en la bibliograf&#237;a trabajos donde demuestran tensiones intradi&#225;lisis m&#225;s bajas con calcios del ba&#241;o m&#225;s bajos<a class="elsevierStyleCrossRefs" href="#bib0440"><span class="elsevierStyleSup">40&#44;41</span></a>&#44; no hemos encontrado trabajos que midan la relaci&#243;n de la concentraci&#243;n del calcio del ba&#241;o con los valores de TA del MAPA&#46;</p><p id="par0460" class="elsevierStylePara elsevierViewall">Diuresis residual&#58; Esta disminuir&#237;a la ganancia de peso interdi&#225;lisis y el volumen de l&#237;quido extracelular&#44; se asociar&#237;a con una mejor correcci&#243;n de la anemia y disminuci&#243;n del consumo de eritropoyetina y menores niveles de citoquinas inflamatorias<a class="elsevierStyleCrossRefs" href="#bib0450"><span class="elsevierStyleSup">42-44</span></a>&#46; No obstante&#44; no encontramos en la literatura estudios que analicen par&#225;metros de MAPA y diuresis residual&#46; En nuestro trabajo las TAD fueron m&#225;s bajas en aquellos pacientes con m&#225;s diuresis residual probablemente debido a un mejor control de la volemia&#46;</p><p id="par0465" class="elsevierStylePara elsevierViewall">Dosis de EPO&#58; La HTA es un efecto secundario conocido de la EPO&#46; Nosotros hemos obtenido una relaci&#243;n significativa de la dosis de EPO tanto con la TAS como TAD promedio&#46; Existen varios trabajos que observaron una correlaci&#243;n significativa entre dosis de EPO y TA&#44; como por ejemplo el trabajo Agarwal&#44; donde la misma se asoci&#243; con mayor prevalencia de HTA independientemente de c&#243;mo fuese esta medida&#44; pre&#44; post o interdi&#225;lisis<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">6</span></a>&#44; Liu et al&#46;&#44; en su trabajo con 90 pacientes en HD&#44; observ&#243; una asociaci&#243;n entre dosis de EPO altas y ritmo circadiano m&#225;s adversos<a class="elsevierStyleCrossRef" href="#bib0350"><span class="elsevierStyleSup">22</span></a>&#46;</p><p id="par0470" class="elsevierStylePara elsevierViewall">DM&#58; La HTA es frecuente en pacientes diab&#233;ticos y se cree podr&#237;a deberse al impacto de la resistencia a la insulina sobre el ri&#241;&#243;n y el &#225;rbol vascular<a class="elsevierStyleCrossRefs" href="#bib0465"><span class="elsevierStyleSup">45-47</span></a>&#46; En nuestro trabajo&#44; la TAD fue m&#225;s baja en aquellos pacientes diab&#233;ticos&#46; Datos similares a un estudio de Franklin et al&#46; que obtuvieron datos del estudio transversal NHANES&#44; de 19&#46;808 personas &#40;poblaci&#243;n general de EE&#46;UU&#46; y no espec&#237;ficamente de enfermos renales&#41;&#44; demostrando que la edad&#44; sexo femenino y diabetes se asociaban de forma independiente con TAD m&#225;s bajas en pacientes tratados y no tratados<a class="elsevierStyleCrossRef" href="#bib0480"><span class="elsevierStyleSup">48</span></a>&#46;</p><p id="par0475" class="elsevierStylePara elsevierViewall">IMC&#58; En nuestro trabajo encontramos que las cifras de TAD promedio del MAPA eran m&#225;s altas en aquellos pacientes con menor IMC&#46; En el trabajo de Agarwal<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">6</span></a>&#44; un IMC m&#225;s bajo fue un factor independiente de prevalencia de HTA medida por MAPA y un factor asociado a falta de control de TA&#44; bas&#225;ndose en las tensiones pre-HD&#46;</p><p id="par0480" class="elsevierStylePara elsevierViewall">El dise&#241;o de nuestro estudio presenta debilidades como&#58; no haber podido estudiar la morbimortalidad de los pacientes y no tener un mayor n&#250;mero de pacientes hiperhidratados e hipertensos para tener datos m&#225;s significativos&#46; Por el contrario&#44; entre las fortalezas de este estudio es que existen pocos estudios en el grupo de pacientes en hemodi&#225;lisis utilizando conjuntamente MAPA y BIA&#46;</p><p id="par0485" class="elsevierStylePara elsevierViewall">En conclusi&#243;n&#44; nuestro estudio muestra&#58; 1&#46; La variabilidad de criterio de HTA&#44; seg&#250;n utilicemos cifras de TA durante la sesi&#243;n de HD o distintas tomas de MAPA&#46; 2&#46; La variabilidad de TA en el periodo interdi&#225;lisis&#46; 3&#46; El mejor grado de concordancia que existe entre las TA de las sesiones de HD y el MAPA corresponde a la TAD pre-HD&#46; 4&#46; La utilizaci&#243;n conjunta de la BIA y el MAPA mejora el control de la TA&#46; 5&#46; La dosis de EPO es el factor m&#225;s importante asociado a la HTA en nuestros pacientes&#46;</p></span><span id="sec0125" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0185">Financiaci&#243;n</span><p id="par0495" class="elsevierStylePara elsevierViewall">Los autores declaran que este art&#237;culo no recibi&#243; financiaci&#243;n alguna de ning&#250;n tipo de entidad p&#250;blica o privada&#46;</p></span><span id="sec0130" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0190">Conflicto de intereses</span><p id="par0500" class="elsevierStylePara elsevierViewall">Los autores declaran que no tienen conflicto de intereses relacionados con los contenidos del art&#237;culo&#46;</p></span></span>"
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              "titulo" => "Criterios de inclusi&#243;n"
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              "titulo" => "Criterios de exclusi&#243;n"
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              "titulo" => "Definici&#243;n de HTA y mediciones de las tensiones arteriales&#58;"
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              "titulo" => "An&#225;lisis estad&#237;stico"
            ]
          ]
        ]
        6 => array:3 [
          "identificador" => "sec0065"
          "titulo" => "RESULTADOS"
          "secciones" => array:7 [
            0 => array:2 [
              "identificador" => "sec0070"
              "titulo" => "Caracter&#237;sticas generales"
            ]
            1 => array:2 [
              "identificador" => "sec0075"
              "titulo" => "TA durante la sesi&#243;n de hemodi&#225;lisis"
            ]
            2 => array:2 [
              "identificador" => "sec0080"
              "titulo" => "TA mediante MAPA"
            ]
            3 => array:2 [
              "identificador" => "sec0085"
              "titulo" => "Concordancia entre tensiones de las sesiones y del MAPA"
            ]
            4 => array:2 [
              "identificador" => "sec0090"
              "titulo" => "F&#225;rmacos antihipertensivos y MAPA"
            ]
            5 => array:2 [
              "identificador" => "sec0095"
              "titulo" => "Hiperhidrataci&#243;n y BIS"
            ]
            6 => array:3 [
              "identificador" => "sec0100"
              "titulo" => "Factores asociados a TA del MAPA"
              "secciones" => array:1 [
                0 => array:2 [
                  "identificador" => "sec0105"
                  "titulo" => "TAS promedio"
                ]
              ]
            ]
          ]
        ]
        7 => array:2 [
          "identificador" => "sec0110"
          "titulo" => "Discusi&#243;n"
        ]
        8 => array:2 [
          "identificador" => "sec0125"
          "titulo" => "Financiaci&#243;n"
        ]
        9 => array:2 [
          "identificador" => "sec0130"
          "titulo" => "Conflicto de intereses"
        ]
        10 => array:1 [
          "titulo" => "Bibliograf&#237;a"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2020-01-27"
    "fechaAceptado" => "2020-06-11"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1373743"
          "palabras" => array:4 [
            0 => "Hemodi&#225;lisis"
            1 => "Hipertensi&#243;n arterial"
            2 => "Monitorizaci&#243;n ambulatoria de la presi&#243;n arterial"
            3 => "Bioimpedancia espectrosc&#243;pica"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1373744"
          "palabras" => array:4 [
            0 => "Haemodialysis"
            1 => "Hypertension"
            2 => "Ambulatory blood pressure monitoring"
            3 => "Bioimpedance spectroscopy"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introducci&#243;n</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La hipertensi&#243;n arterial &#40;HTA&#41; en los pacientes en hemodi&#225;lisis &#40;HD&#41; es muy frecuente y se asocia a un aumento de la morbimortalidad&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Los objetivos de nuestro trabajo han sido&#58; 1&#46; Conocer la tensi&#243;n arterial &#40;TA&#41; en la sesi&#243;n de HD&#46; 2&#46; Estudiar la TA&#44; en el periodo interdial&#237;tico&#44; mediante monitorizaci&#243;n ambulatoria de presi&#243;n arterial &#40;MAPA&#41; de 44 horas&#46; 3&#46; Conocer la concordancia entre la TA en la sesi&#243;n de HD y MAPA&#46; 4&#46; Valorar los cambios de tratamiento despu&#233;s de la realizaci&#243;n del MAPA&#46; 5&#46; Realizar una bioimpedancia espectrosc&#243;pica &#40;BIS&#41; a todos los pacientes y en los hiperhidratados e hipertensos&#44; seg&#250;n MAPA&#44; valorar cambios en la TA despu&#233;s de ajustar el peso seco &#40;PS&#41;&#46; 6&#46; Conocer factores asociados a la TA sist&#243;lica &#40;TAS&#41; y TA diast&#243;lica &#40;TAD&#41; promedio del MAPA&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material y m&#233;todos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo observacional&#44; que incluy&#243; a 100 pacientes de nuestra unidad de di&#225;lisis&#46; Se han recogido las tensiones pre y post-HD&#44; durante dos semanas y&#44; posteriormente&#44; colocamos a los pacientes un aparato de MAPA a mitad de semana&#44; durante 44 horas&#46; Previo a comenzar la siguiente sesi&#243;n de di&#225;lisis&#44; realizamos una BIS&#46; A aquellos pacientes hiperhidratados e hipertensos&#44; seg&#250;n MAPA&#44; se les realiz&#243; un segundo MAPA para valorar cambios en los valores de TA&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Seg&#250;n MAPA&#44; el 65&#37; de pacientes presentaron una TA diurna &#62; 135&#47;85 mmHg&#44; 90&#37; TA nocturna &#62; 120&#47;70 mmHg y 76&#37; TA promedio &#62; 130&#47;80 mmHg&#46; El 11&#37; present&#243; un patr&#243;n <span class="elsevierStyleItalic">dipper</span>&#44; 51&#37; no <span class="elsevierStyleItalic">dipper</span> y 38&#37; <span class="elsevierStyleItalic">riser</span>&#46; Las TAS y TAD promedio fueron 4&#44;7 mmHg &#40;3&#44;8&#37;&#41; y 1&#44;1 mmHg &#40;1&#44;64&#37;&#41; m&#225;s altas el segundo d&#237;a&#46; En el 6&#37; de pacientes fue necesario bajar la dosis de antihipertensivos&#44; 9&#37; suspenderlos&#44; 28&#37; aumentar dosis y 17&#37; a&#241;adir un nuevo f&#225;rmaco&#46; La TAD pre-HD es la que mejor concordancia presenta con el MAPA&#46; Despu&#233;s de realizar BIS y ajustar PS hubo un descenso significativo en todas las cifras de TA&#46; El an&#225;lisis univariante mostr&#243; que la TAS promedio fue m&#225;s alta en pacientes con ba&#241;o alto en calcio&#44; mayor cantidad de f&#225;rmacos antihipertensivos y mayores dosis de eritropoyetina &#40;EPO&#41;&#46; El an&#225;lisis multivariante mostr&#243; asociaci&#243;n significativa para EPO y n&#250;mero de f&#225;rmacos &#40;p &#60; 0&#44;01&#41;&#46; La TAD promedio fue m&#225;s alta en pacientes m&#225;s j&#243;venes&#44; con Charlson m&#225;s bajos&#44; menor &#237;ndice de masa corporal &#40;IMC&#41;&#44; menos diuresis&#44; no diab&#233;ticos y con mayores dosis de EPO&#46; El estudio de regresi&#243;n lineal mostr&#243; como variables significativas la edad &#40;p &#60; 0&#44;005&#41;&#44; IMC &#40;p &#60; 0&#44;03&#41; y EPO &#40;p &#60; 0&#44;03&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Nuestro estudio muestra&#58; 1&#46; La variabilidad de criterio de HTA&#44; seg&#250;n utilicemos cifras de TA durante la sesi&#243;n de HD o MAPA&#46; 2&#46; La variabilidad de TA en el periodo interdi&#225;lisis&#46; 3&#46; La TAD predi&#225;lisis es la que mejor concordancia presenta con el MAPA&#46; 4&#46; La utilizaci&#243;n conjunta de la BIS y el MAPA mejora el control de la TA&#46; 5&#46; La dosis de EPO es el factor m&#225;s importante asociado a la HTA en nuestros pacientes&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introducci&#243;n"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introduction</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Hypertension is very common in haemodialysis &#40;HD&#41; patients&#44; and is associated with increased morbidity and mortality rates&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The goals of our research were to&#58; 1&#46; Measure blood pressure &#40;BP&#41; during HD sessions&#59; 2&#46; Study BP in between HD sessions with 44-hour Ambulatory Blood Pressure Monitoring &#40;ABPM&#41;&#59; 3&#46; Identify differences between the BP recorded during HD and with the ABPM&#59; 4&#46; Evaluate changes in treatment after the ABPM&#59; 5&#46; Perform bioimpedance spectroscopy &#40;BIS&#41; on all patients and&#44; in those hyper-hydrated or hypertensive according to ABPM&#44; assess for changes in BP after adjusting the dry weight&#59; 6&#46; Identify factors associated with average systolic and diastolic BP measured by ABPM&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Material and methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Prospective observational study&#44; which included 100 patients from our dialysis unit&#46; We measured BP before and after the HD sessions for two weeks and then&#44; mid-week&#44; we attached the ABPM device to the patients for 44 hours&#46; Before starting the following dialysis session&#44; we performed BIS&#46; A second ABPM was performed on hyper-hydrated patients and patients hypertensive according to ABPM to evaluate changes in BP values&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">According to the ABPM&#44; 65&#37; of patients had daytime BP &#62; 135&#47;85 mmHg&#44; 90&#37; night-time BP &#62; 120&#47;70 mmHg and 76&#37; average BP &#62; 130&#47;80 mmHg&#59; 11&#37; had a dipper pattern&#44; 51&#37; non-dipper and 38&#37; riser&#46; The average systolic and diastolic BP readings were 4&#46;7 mmHg &#40;3&#46;8&#37;&#41; and 1&#46;1 mmHg &#40;1&#46;64&#37;&#41; higher on the second day&#46; The dose of antihypertensive medication had to be lowered in 6&#37; of patients&#44; 9&#37; had to stop taking it&#44; 28&#37; needed increased doses and 17&#37; had to add a new drug&#46; The pre-HD diastolic BP best matched the ABPM&#46; After performing the bioimpedance and adjusting dry weight&#44; there was a statistically significant decrease in all BP values&#46; The univariate analysis showed that the average systolic BP was higher in patients with a high-calcium dialysis bath&#44; more antihypertensive drugs and higher doses of EPO&#46; The multivariate analysis showed significant association for EPO and number of drugs &#40;p &#60; 0&#46;01&#41;&#46; The average diastolic BP was higher in younger patients and patients with lower Charlson index&#44; lower body mass index and less diuresis&#44; those on higher doses of EPO and non-diabetics&#46; The linear regression study showed age &#40;p &#60; 0&#46;005&#41;&#44; body mass index &#40;p &#60; 0&#46;03&#41; and EPO &#40;p &#60; 0&#46;03&#41; as significant variables&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Our study shows&#58; 1&#46; The variability of hypertension criteria according to use of BP values from during the HD session or ABPM&#59; 2&#46; The variability of BP in the interdialysis period&#59; 3&#46; That the pre-dialysis diastolic BP best corresponds with the ABPM&#46; 4&#46; That the use of both BIS and ABPM improves the control of BP&#59; 5&#46; That the dose of EPO is the most important factor associated with hypertension in our patients&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusions"
          ]
        ]
      ]
    ]
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        "etiqueta" => "Tabla 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
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            "identificador" => "at1"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
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        "tabla" => array:1 [
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            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Caracter&#237;sticas cl&#237;nicas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">N &#61; 100&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A&#241;os&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">61&#44;87 &#43;&#47;- 14&#44;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sexo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">61 varones 39 mujeres&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">IMC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26&#44;30 &#43;&#47;-4&#44;69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Etiolog&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">DM&#58;34&#37;&#59; Glomerulonefritis&#58;15&#37;&#59; Vascular&#58; 12&#37;&#59; Poliquistosis&#58;10&#37;&#59; Intersticial&#58;6&#37;&#59; No filiada&#58; 23&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Charlson &#40;sin edad&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;9 &#43;&#47;- 1&#44;84&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tiempo en hemodi&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">49 &#43;&#47;- 2&#44;46 meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">KTV est&#225;ndar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;17 &#43;&#47;- 0&#44;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Duraci&#243;n de sesiones&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">222 &#43;&#47;- 17&#44;58 minutos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Promedio de ultrafiltraci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2136 &#43;&#47;- 788&#44;4 mL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">kg interdi&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;88 &#43;&#47;- 0&#44;83 kg&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diuresis residual&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">781&#44;15 &#43;&#47;- 705&#44;76 mL&#47;d&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hemoglobina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;33 &#43;&#47;- 7&#44;42 g&#47;dL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dosis de eritropoyetina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">128&#44;32 &#43;&#47;- 127&#44;58 UI&#47;kg&#47;semana&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#205;ndice de resistencia a la EPO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;72 &#43;&#47;- 6&#44;04 dosis de EPO semanal&#47;peso&#47;g hemoglobina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">N&#250;mero de f&#225;rmacos antihipertensivos&#58;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>1-2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>3 o m&#225;s&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">52&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Tipos de antihipertensivos utilizados&#58;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Antagonistas c&#225;lcicos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Beta bloqueantes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">54&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>ARA II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">42&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Alfa bloqueantes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>IECAS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Simpaticol&#237;ticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Vasodilatador arterial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Antagonista central&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Tensiones pre-HD&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Tensiones post-HD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA sist&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">53&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA diast&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA sistodiast&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No HTA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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          "es" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Porcentaje de pacientes hipertensos en las sesiones de di&#225;lisis</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Tensiones diurnas&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA sist&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA diast&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HTA sistodiast&#243;lica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">66&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">39&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">No HTA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
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                0 => "xTab2600699.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Porcentaje de pacientes hipertensos seg&#250;n MAPA</p>"
        ]
      ]
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        "etiqueta" => "Tabla 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at4"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Di&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="2" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Tensi&#243;n Arterial Sist&#243;lica</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Coeficiente de correlaci&#243;n intraclase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Interpretaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;605 &#91;0&#44;465-0&#44;716&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;480 &#91;0&#44;313-0&#44;617&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mediocre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;596 &#91;0&#44;453-0&#44;709&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;455 &#91;0&#44;285-0&#44;597&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mediocre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;616 &#91;0&#44;478-0&#44;724&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;484 &#91;0&#44;319-0&#44;621&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mediocre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2600696.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Concordancia entre tensiones arteriales sist&#243;licas de las sesiones y del MAPA</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0025"
        "etiqueta" => "Tabla 5"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at5"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Di&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="2" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">Tensi&#243;n arterial diast&#243;lica</span></th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Coeficiente de correlaci&#243;n intraclase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Interpretaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;744 &#91;0&#44;642-0&#44;820&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Buena&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;649 &#91;0&#44;520-0&#44;750&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;696 &#91;0&#44;579-0&#44;785&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;599 &#91;0&#44;457-0&#44;711&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;743 &#91;0&#44;641-0&#44;820&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Buena&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Post&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;640 &#91;0&#44;508-0&#44;742&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Moderada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2600693.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Concordancia entre tensiones arteriales diast&#243;licas de las sesiones y del MAPA</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0030"
        "etiqueta" => "Tabla 6"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at6"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAS diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAD diurna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAS nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAD nocturna&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAS promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAD promedio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MAPA 1 &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">149&#44;86 &#43;&#47;- 15&#44;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">86&#44;07 &#43;&#47;-13&#44;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">144&#44;86 &#43;&#47;- 20&#44;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81&#44;57 &#43;&#47;-16&#44;52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">148&#44;57&#43;&#47;-16&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">84&#44;64 &#43;&#47;-13&#44;99&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MAPA 2 &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">137&#44;14 &#43;&#47;- 15&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">79&#44;29 &#43;&#47;-9&#44;78&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">129&#44;14 &#43;&#47;-12&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">71&#44;93 &#43;&#47;-9&#44;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">135&#44;71 &#43;&#47;-12&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">77&#44;93 &#43;&#47;- 8&#44;88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Porcentaje de descenso &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;12 &#43;&#47;- 9&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;25 &#43;&#47;-7&#44;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;67 &#43;&#47;-11&#44;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;36 &#43;&#47;-9&#44;94&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;13 &#43;&#47;-9&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;04 &#43;&#47;- 7&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">P&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2600700.png"
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            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Cambios en las cifras de tensiones tras ajustes de peso seco</p>"
        ]
      ]
      6 => array:8 [
        "identificador" => "tbl0035"
        "etiqueta" => "Tabla 7"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at7"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">OH&#58; Sobrehidrataci&#243;n&#46; ECW&#58; Agua extracelular&#46; TBW&#58; Agua corporal total&#46; ICW&#58; Agua intracelular&#46; E&#47;I&#58; Relaci&#243;n&#58; agua extracelular&#47;agua intracellular&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">OH2-OH1</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">ECW2-ECW1</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">TBW2-TBW1</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">ICW2-ICW1</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleBold">E&#47;I2- E&#47;I1</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diferencia &#40;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-3&#44;182&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-3&#44;190&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-2&#44;098&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;535&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-2&#44;841&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;036&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;593&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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                0 => "xTab2600695.png"
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        "descripcion" => array:1 [
          "es" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Variaci&#243;n de los par&#225;metros entre la primera y segunda bioimpedancia</p>"
        ]
      ]
      7 => array:8 [
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        "etiqueta" => "Tabla 8"
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        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at8"
            "detalle" => "Tabla "
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        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="4" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variables relacionadas con los pacientes</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Coeficiente de correlaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAS promedio de MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Valor de P&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Edad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pearson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;97&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">IMC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pearson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Charlson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;84&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tiempo en HD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;078&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;441&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diuresis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;013&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;896&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">N&#250;m&#46; de f&#225;rmacos antihipertensivos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;255&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Variables relacionadas con la di&#225;lisis</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Coeficiente de correlaci&#243;n</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">TAS promedio de MAPA</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Valor de p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Promedio de ultrafiltraci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;073&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ganancia de peso interdi&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;087&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Variables relacionadas con la anemia</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Coeficiente de correlaci&#243;n</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">TAS promedio de MAPA</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Valor de p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EPO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;265&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;008&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hb&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;073&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;468&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Resistencia a la EPO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;172&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;087&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="4" align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variables relacionadas con los pacientes</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Coeficiente de correlaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">TAD promedio de MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Edad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pearson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">IMC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pearson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Charlson&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;004&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tiempo en HD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diuresis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;027&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">N&#250;m&#46; de f&#225;rmacos antihipertensivos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;073&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Variables relacionadas con la di&#225;lisis</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Coeficiente de correlaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TAD promedio de MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Promedio de ultrafiltraci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;057&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;57&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ganancia de peso interdi&#225;lisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;028&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;78&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Variables relacionadas con la anemia</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Coeficiente de correlaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TAD promedio de MAPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EPO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;009&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hb&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-0&#44;11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Resistencia a la EPO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Spearman&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;056&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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        "descripcion" => array:1 [
          "es" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">Variables cuantitativas y su relaci&#243;n con TAD promedio seg&#250;n MAPA</p>"
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                            5 => "M&#46;R&#46; Weir"
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                      "titulo" => "Prevalence&#44; treatment&#44; and control of hypertension in chronic hemodialysis patients in the United States"
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                            3 => "D&#46;W&#46; Coyne"
                            4 => "J&#46;R&#46; Trout"
                            5 => "D&#46;G&#46; Warnock"
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Med&#46;"
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                        "volumen" => "115"
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                        "paginaFinal" => "297"
                      ]
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            2 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertension and survival in chronic hemodialysis patients&#8211; past lessons and future opportunities"
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                    0 => array:2 [
                      "doi" => "10.1111/j.1523-1755.2005.00050.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int&#46;"
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                        "volumen" => "67"
                        "paginaInicial" => "1"
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                        "link" => array:1 [
                          0 => array:2 [
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypertension in the hemodialysis population&#58; a survey of 649 patients"
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                        0 => array:2 [
                          "etal" => false
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                            0 => "M&#46;M&#46; Salem"
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                      "doi" => "10.1016/0272-6386(95)90492-1"
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                        "tituloSerie" => "Am J Kidney Dis&#46;"
                        "fecha" => "1995"
                        "volumen" => "26"
                        "paginaInicial" => "461"
                        "paginaFinal" => "468"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7645554"
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                      "titulo" => "Factors associated with inadequate blood pressure control in hypertensive hemodialysis patients"
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                            0 => "M&#46; Rahman"
                            1 => "A&#46; Dixit"
                            2 => "V&#46; Donley"
                            3 => "S&#46; Gupta"
                            4 => "T&#46; Hanslik"
                            5 => "E&#46; Lacson"
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                    0 => array:2 [
                      "doi" => "10.1016/s0272-6386(99)70187-3"
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                        "tituloSerie" => "Am J Kidney Dis&#46;"
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                        "volumen" => "33"
                        "paginaInicial" => "498"
                        "paginaFinal" => "506"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10070914"
                            "web" => "Medline"
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