array:22 [
  "pii" => "S0211699524001085"
  "issn" => "02116995"
  "doi" => "10.1016/j.nefro.2024.10.007"
  "estado" => "S5"
  "fechaPublicacion" => "2024-10-25"
  "aid" => "1298"
  "copyright" => "Sociedad Española de Nefrología"
  "copyrightAnyo" => "2024"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:17 [
    "pii" => "S0211699524000961"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2024.10.002"
    "estado" => "S100"
    "fechaPublicacion" => "2024-10-28"
    "aid" => "1293"
    "copyright" => "Sociedad Española de Nefrología"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "La litiasis renal en los reyes de la casa de Austria&#46; &#191;El primer caso conocido de pielonefritis xantogranulomatosa&#63;"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "V&#237;ctor M&#46; Garc&#237;a Nieto, Justo Hern&#225;ndez Gonz&#225;lez, Matilde Clara Gil Villena"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "V&#237;ctor M&#46;"
              "apellidos" => "Garc&#237;a Nieto"
            ]
            1 => array:2 [
              "nombre" => "Justo"
              "apellidos" => "Hern&#225;ndez Gonz&#225;lez"
            ]
            2 => array:2 [
              "nombre" => "Matilde Clara"
              "apellidos" => "Gil Villena"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699524000961?idApp=UINPBA000064"
    "url" => "/02116995/unassign/S0211699524000961/v1_202410280408/es/main.assets"
  ]
  "itemAnterior" => array:16 [
    "pii" => "S0211699521002150"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2021.09.007"
    "estado" => "S5"
    "fechaPublicacion" => "2022-10-28"
    "aid" => "976"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "ret"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "WITHDRAWN&#58; Carta al editor&#58; Factores de riesgo de lesi&#243;n renal aguda en adultos con covid-19"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => "en"
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Xiaoyue Cai, Guiming Wu, Jie Zhang, Lichuan Yang"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Xiaoyue"
              "apellidos" => "Cai"
            ]
            1 => array:2 [
              "nombre" => "Guiming"
              "apellidos" => "Wu"
            ]
            2 => array:2 [
              "nombre" => "Jie"
              "apellidos" => "Zhang"
            ]
            3 => array:2 [
              "nombre" => "Lichuan"
              "apellidos" => "Yang"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699521002150?idApp=UINPBA000064"
    "url" => "/02116995/unassign/S0211699521002150/v2_202302211535/en/main.assets"
  ]
  "en" => array:11 [
    "idiomaDefecto" => true
    "titulo" => "The Role of Strain Wave Elastography in The Evaluation of Renal Fibrosis in Patients with Kidney Diseases"
    "tieneTextoCompleto" => 0
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Hanaa Ibrahim Okda, Rabab Alaa Eldin Keshk, Noha Elanwar, Ahmed Mohammed El Behiry, Sally Maher Gamaleldin"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Hanaa Ibrahim"
            "apellidos" => "Okda"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Rabab Alaa Eldin"
            "apellidos" => "Keshk"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Noha"
            "apellidos" => "Elanwar"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Ahmed Mohammed El"
            "apellidos" => "Behiry"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">3</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          4 => array:4 [
            "nombre" => "Sally Maher"
            "apellidos" => "Gamaleldin"
            "email" => array:1 [
              0 => "Drsally2000@yahoo.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Department of Internal Medicine&#44; Faculty of Medicine&#44; Tanta University&#44; Egypt"
            "etiqueta" => "1"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Department of Pathology&#44; Faculty of Medicine&#44; Tanta University&#44; Egypt"
            "etiqueta" => "2"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Department of Radiology&#44; Faculty of Medicine&#44; Tanta University&#44; Egypt"
            "etiqueta" => "3"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#58; Department of Internal Medicine&#44; Faculty of Medicine&#44; Tanta University&#44; Egypt"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2024-07-27"
    "fechaAceptado" => "2024-10-20"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1898706"
          "palabras" => array:4 [
            0 => "Strain wave"
            1 => "Elastography"
            2 => "Renal biopsy"
            3 => "Fibrosis"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Background&#58; A renal biopsy represents the gold standard in the diagnosis&#44; prognosis and management of patients with chronic kidney disease and glomerulonephritis&#46; Strain wave elastography &#40;SE&#41; is a developing technique to assess tissue elasticity&#46; The aim of this study was to correlate between the strain index value of renal parenchyma and degree of renal fibrosis detected with renal biopsy&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Method&#58; For 68 patients who were referred for a kidney biopsy&#44; SE test was performed&#46; The Banff scoring system was utilized to classify the IFTA grading of kidney fibrosis that assigns a severity level of mild&#44; moderate&#44; or severe&#46; Receiver operating characteristic curve &#40;ROC&#41; was utilized to correlate between the severity of renal fibrosis and the grade of renal elasticity determined by SE&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Results&#58; In total&#44; 38 males and 30 females&#44; the echogenicity&#44; qualitative and semiquantitative elastography showed significant positive correlation with serum creatinine&#44; percentage of fibrosis&#44; G score and tubular atrophy and significant negative correlation with eGFR&#46; ROC curve of SE for diagnosis of interstitial fibrosis shown that echogenicity has sensitivity 100&#46;0&#37;&#44; Specificity 62&#46;5&#37;&#44; positive predictive value &#40;PPV&#41; 75&#46;0&#37;&#44; negative predictive value &#40;NPV&#41; 100&#46;0&#37; with area under curve &#40;AUC&#41; 0&#46;906&#44; while qualitative elastography has sensitivity 77&#46;8&#37;&#44; specificity 75&#46;0&#37;&#44; PPV 77&#46;8&#37;&#44; NPV 75&#46;0&#37; AUC 0&#46;833&#44; semi quantitative elastography has sensitivity 83&#46;3&#37;&#44; specificity 93&#46;8&#37;&#44; PPV 93&#46;8&#37;&#44; NPV 83&#46;3&#37; with AUC 0&#46;915&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Conclusion&#58; SE approach is simple to use&#44; and can differentiate between varying stages of renal fibrosis&#46; However&#44; further research is required before it can be frequently used in clinical practice&#46;</p></span>"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/02116995/unassign/S0211699524001085/v1_202410250436/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/02116995/unassign/S0211699524001085/v1_202410250436/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699524001085?idApp=UINPBA000064"
]
Compartir
Información de la revista
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Acceso a texto completo
Pruebas previas, online el 25 de octubre de 2024
The Role of Strain Wave Elastography in The Evaluation of Renal Fibrosis in Patients with Kidney Diseases
Visitas
51
Hanaa Ibrahim Okda1, Rabab Alaa Eldin Keshk1, Noha Elanwar2, Ahmed Mohammed El Behiry3, Sally Maher Gamaleldin1,
Autor para correspondencia
Drsally2000@yahoo.com

Corresponding author: Department of Internal Medicine, Faculty of Medicine, Tanta University, Egypt
1 Department of Internal Medicine, Faculty of Medicine, Tanta University, Egypt
2 Department of Pathology, Faculty of Medicine, Tanta University, Egypt
3 Department of Radiology, Faculty of Medicine, Tanta University, Egypt
Este artículo ha recibido
Información del artículo
Abstract

Background: A renal biopsy represents the gold standard in the diagnosis, prognosis and management of patients with chronic kidney disease and glomerulonephritis. Strain wave elastography (SE) is a developing technique to assess tissue elasticity. The aim of this study was to correlate between the strain index value of renal parenchyma and degree of renal fibrosis detected with renal biopsy.

Method: For 68 patients who were referred for a kidney biopsy, SE test was performed. The Banff scoring system was utilized to classify the IFTA grading of kidney fibrosis that assigns a severity level of mild, moderate, or severe. Receiver operating characteristic curve (ROC) was utilized to correlate between the severity of renal fibrosis and the grade of renal elasticity determined by SE.

Results: In total, 38 males and 30 females, the echogenicity, qualitative and semiquantitative elastography showed significant positive correlation with serum creatinine, percentage of fibrosis, G score and tubular atrophy and significant negative correlation with eGFR. ROC curve of SE for diagnosis of interstitial fibrosis shown that echogenicity has sensitivity 100.0%, Specificity 62.5%, positive predictive value (PPV) 75.0%, negative predictive value (NPV) 100.0% with area under curve (AUC) 0.906, while qualitative elastography has sensitivity 77.8%, specificity 75.0%, PPV 77.8%, NPV 75.0% AUC 0.833, semi quantitative elastography has sensitivity 83.3%, specificity 93.8%, PPV 93.8%, NPV 83.3% with AUC 0.915.

Conclusion: SE approach is simple to use, and can differentiate between varying stages of renal fibrosis. However, further research is required before it can be frequently used in clinical practice.

Keywords:
Strain wave
Elastography
Renal biopsy
Fibrosis
El Texto completo está disponible en PDF
Copyright © 2024. Sociedad Española de Nefrología
Descargar PDF
Idiomas
Nefrología
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?