SureClick® (darbepoetina alfa) puede mejorar la satisfacción percibida y la competencia para el tratamiento de la anemia y aumentar la tasa de autoadministración en pacientes con enfermedad renal crónica no dializados

Grupo del Estudio PREFERENCE; Bonafont, Xavier; Romero, Ramón; Romero, R.; Martínez, Isabel; Martínez, I.; del Pino, María D.; del Pino, M.D.; Gil, José M.; Gil, J.M.; Aranda, Pedro; Aranda, P.; Roca, Ramón; Claverol, J.; Claverol, Joana; Cucala, M.; Cucala, Mercedes

doi:10.3265/Nefrologia.pre2012.Oct.11535

Información del artículo

Antecedentes y objetivos: SureClick® es una pluma precargada para la administración de darbepoetina alfa (DA), que está lista para usar. Se exploró la satisfacción del paciente con SureClick® en comparación con las jeringas precargadas. Métodos: Estudio observacional multicéntrico, prospectivo, de 6 meses, en el que se incluyeron pacientes no dializados con enfermedad renal crónica (ERC) tratados con DA en jeringas precargadas que cambiaron a SureClick® al inicio del estudio. Las principales variables fueron: cambios en el Cuestionario de Satisfacción con el Tratamiento de la Anemia (ATSQ-S), Escala de Competencia Percibida en el Manejo de la Anemia (PCAS) y el porcentaje de autoadministración. Resultados: Se incluyeron 132 pacientes con una media (± desviación estándar [DE]) de 71,3 (14,6) años y un 57,6 % de mujeres. Las puntuaciones basales y finales medias (DE) en la ATSQ-S fueron, respectivamente, 25,5 (7,9) y 31,6 (4,9) (en una escala de 0 a 36-máxima satisfacción, cambio medio: 6,2, intervalo de confianza [IC] 95%: 4,6-7,8, p < 0,0001). La puntuación de la PCAS también aumentó significativamente (4,3 [2,0] vs. 5,6 [1,6], en una escala de 1 a 7-máxima competencia, p < 0,0001). Al inicio del estudio, el 47,7 % de los pacientes se autoadministraba DA con jeringas precargadas, frente al 74,2 % con SureClick® (p < 0,001). No hubo cambios significativos en el nivel medio de hemoglobina (11,4 [0,5] vs. 11,6 [1,3] g/dl, p = 0,193). Dos pacientes (1,5 %) presentaron reacciones adversas a SureClick® (dolor en el lugar de aplicación). Conclusiones: Los resultados sugieren que el cambio de jeringas precargadas a SureClick® podría aumentar la satisfacción del paciente y la percepción de la competencia en el manejo de la anemia en pacientes con ERC no dializados, y podría aumentar la tasa de autoadministración, lo que reduciría el uso de recursos sanitarios.

Palabras clave:

Anemia

Palabras clave:

Competencia

Palabras clave:

Enfermedad renal crónica

Palabras clave:

Satisfacción

Palabras clave:

Darbepoetina alfa

Background and aims: SureClick® is a prefilled pen for administration of darbepoetin alfa (DA) that is ready-to-use. We explored patient satisfaction with SureClick® compared with prefilled syringes (PFS). Methods: Multicenter, prospective, 6-months, observational study in non-dialyzed patients with chronic kidney disease (CKD) treated with DA in PFS who switched to SureClick® at baseline. Main outcomes were: change in Anemia Treatment Satisfaction Questionnaire (ATSQ-S), Perceived Competence for Anemia Scale (PCAS) and self-administration rate. Results: We enrolled 132 patients with a mean(SD) age of 71.3 (14.6) years, 57.6% women. Mean(SD) ATSQ-S scores at baseline and final records were 25.5 (7.9) and 31.6 (4.9) (on a scale from 0 to 36 –maximum satisfaction-, mean change: 6.2, 95%CI: 4.6-7.8, p<0.0001). The PCAS also increased significantly (4.3 (2.0) vs 5.6 (1.6), on a scale from 1 to 7 –maximum competence, p<0.0001). At baseline 47.7% of patients self-administered DA with PFS, vs 74.2% with SureClick® (p<0.001). No significant changes in hemoglobin were observed (11.4 (0.5) vs 11.6 (1.3) g/dl, p=0.193). Two patients (1.5%) had adverse reactions to SureClick® (pain on application). Conclusions: Our results suggest that the change from PFS to SureClick® could increase patient satisfaction and perceived competence in anemia management in non-dialyzed CKD patients, and could increase the self-administration rate, thereby reducing use of health resources.

Keywords:

Anemia

Keywords:

Competence

Keywords:

Chronic kidney disease

Keywords:

Satisfaction

Keywords:

Darbepoetin alfa

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