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Vol. 26. Issue. 6.December 2006
Pages 651-759
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Vol. 26. Issue. 6.December 2006
Pages 651-759
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Secondary Amyloidosis with Irreversible Acute Renal Failure Caused by Visceral Leishmaniasis in a Patient with AIDS
AMILOIDOSIS SECUNDARIA POR LEISHMANIASIS VISCERAL COMO CAUSA DE FRACASO RENAL AGUDO IRREVERSIBLE EN PACIENTE CON SIDA
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Maruja Navarro Díaz Nefrología Hospital Universitario Germans Trias i Pujol, Josep Bonet Sol Nefrología Hospital Universitario Germans Trias i Pujol,
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We report a case of visceral leishmaniasis and acute renal failure in a white male patient, 28 years of age, infected with the human immunodeficiency virus (HIV). The clinical presentation of the patient was diarrheic syndrome of long evolution, fever, hepatosplenomegaly and pancytopenia, accompanied by nephrotic syndrome and irreversible acute renal failure. Renal biopsy showed glomerular AA amyloid deposits. This is the first case described in humans of secondary amyloidosis caused by visceral leishmaniasis.
Keywords:
amyloidosis, leishmaniasis, irreversible acute renal failure and HIV
Describimos el caso de un varón de raza blanca de 28 años de edad con infección por el virus de la inmunodeficiencia humana, que presenta leishmaniasis visceral y fracaso renal agudo. Clínicamente se presenta como síndrome diarreico de larga evolución, fiebre, hepatoesplenomegalia y pancitopenia, junto con síndrome nefrótico y fracaso renal agudo irreversible. La biopsia renal demuestra depósitos de amiloide AA glomerulares. Es el primer caso descrito en humanos de amiloidosis secundaria por leishmaniasis visceral.
Palabras clave:
amiloidosis, leishmaniasis, fracaso renal agudo irreversible, VIH

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