array:24 [
  "pii" => "S2013251418300178"
  "issn" => "20132514"
  "doi" => "10.1016/j.nefroe.2018.01.005"
  "estado" => "S300"
  "fechaPublicacion" => "2018-01-01"
  "aid" => "407"
  "copyright" => "Sociedad Española de Nefrología"
  "copyrightAnyo" => "2017"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "sco"
  "cita" => "Nefrologia (English Version). 2018;38:1-3"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 2643
    "formatos" => array:3 [
      "EPUB" => 245
      "HTML" => 1817
      "PDF" => 581
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S021169951730142X"
      "issn" => "02116995"
      "doi" => "10.1016/j.nefro.2017.06.005"
      "estado" => "S300"
      "fechaPublicacion" => "2018-01-01"
      "aid" => "407"
      "copyright" => "Sociedad Española de Nefrología"
      "documento" => "article"
      "crossmark" => 0
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "sco"
      "cita" => "Nefrologia. 2018;38:1-3"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 8556
        "formatos" => array:3 [
          "EPUB" => 361
          "HTML" => 7086
          "PDF" => 1109
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
        "titulo" => "Seguridad en hemodi&#225;lisis&#58; paradigma del trabajo en equipo"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "1"
            "paginaFinal" => "3"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Safety on haemodialysis&#58; Team work paradigm"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "M&#46; Dolores Arenas Jim&#233;nez, Manuel Mac&#237;a-Heras"
            "autores" => array:2 [
              0 => array:2 [
                "nombre" => "M&#46; Dolores"
                "apellidos" => "Arenas Jim&#233;nez"
              ]
              1 => array:2 [
                "nombre" => "Manuel"
                "apellidos" => "Mac&#237;a-Heras"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2013251418300178"
          "doi" => "10.1016/j.nefroe.2018.01.005"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251418300178?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021169951730142X?idApp=UINPBA000064"
      "url" => "/02116995/0000003800000001/v1_201801090621/S021169951730142X/v1_201801090621/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S201325141830018X"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2018.01.006"
    "estado" => "S300"
    "fechaPublicacion" => "2018-01-01"
    "aid" => "416"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:4-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 8679
      "formatos" => array:3 [
        "EPUB" => 259
        "HTML" => 7235
        "PDF" => 1185
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
      "titulo" => "The dialyser in the year 2017&#58; Much more than a membrane"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "4"
          "paginaFinal" => "7"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "El dializador en el a&#241;o 2017&#58; mucho m&#225;s que una membrana"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1061
              "Ancho" => 1500
              "Tamanyo" => 145186
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Size and distribution of membrane pores&#46;</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">HCO&#58; high cut-off membranes&#59; HF&#58; high-flux plasma filters and dialysers&#59; MCO&#58; medium cut-off membranes&#47;intermediate pores&#59; s&#47;n&#58; standardised number of pores per each size&#44; out of one&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Rafael P&#233;rez-Garc&#237;a, Roberto Alc&#225;zar"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "P&#233;rez-Garc&#237;a"
            ]
            1 => array:2 [
              "nombre" => "Roberto"
              "apellidos" => "Alc&#225;zar"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699517301777"
        "doi" => "10.1016/j.nefro.2017.08.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517301777?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S201325141830018X?idApp=UINPBA000064"
    "url" => "/20132514/0000003800000001/v1_201802180616/S201325141830018X/v1_201802180616/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>"
    "titulo" => "Safety on haemodialysis&#58; Team work paradigm"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "1"
        "paginaFinal" => "3"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Maria Dolores Arenas Jim&#233;nez, Manuel Mac&#237;a-Heras"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "Maria Dolores"
            "apellidos" => "Arenas Jim&#233;nez"
            "email" => array:1 [
              0 => "lola&#64;olemiswebs&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Manuel"
            "apellidos" => "Mac&#237;a-Heras"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Vithas Hospital Perpetuo Internacional&#44; Alicante&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Hospital Universitario Nuestra Se&#241;ora de Candelaria&#44; Santa Cruz de Tenerife&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Seguridad en hemodi&#225;lisis&#58; paradigma del trabajo en equipo"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Safety in healthcare is the absence or the reduction to a minimum acceptable risk of unnecessary harm during the provision of healthcare &#40;source&#58; AMSP&#47;WHO&#58; International Classification for Patient Safety&#41;&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Haemodialysis &#40;HD&#41; entails a series of procedures and techniques&#44; some of which are complex&#44; involving cutting-edge technology &#40;water treatment&#44; monitors&#44; etc&#46;&#41;&#44; the administration of medicinal products and pharmacovigilance&#46; All this occurs in fragile elderly patients with many comorbidities&#44; who make use of healthcare systems in an intense and fragmented fashion&#44; meaning they are at an increased risk of suffering from significant effects&#46;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">1&#44;2</span></a> The likelihood of errors is therefore higher&#44;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">3</span></a> so it is necessary to establish prevention strategies for healthcare-related adverse events&#46; This should be done through a prioritisation system&#44; in accordance with their frequency&#44; severity of the effects and how detectable they are&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">4</span></a> Only close observation of the procedures can guarantee high quality healthcare with better clinical results&#44; fewer complications&#44; the elimination of inadequate procedures and greater patient satisfaction&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The most commonly reported adverse events in kidney diseases occur in hospitalised patients&#46; These include medication errors of up to 40&#46;7&#37;&#44; of which 30&#46;2&#37; were considered avoidable&#46;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">5</span></a> Overall&#44; inadequate monitoring &#40;28&#46;3&#37;&#41;&#44; excessive dosing &#40;21&#46;7&#37;&#41;&#44; selection of an inadequate drug &#40;15&#46;0&#37;&#41;&#44; failure to prescribe the required drug &#40;15&#46;0&#37;&#41; and drug interactions &#40;11&#46;7&#37;&#41; are the most common errors causing avoidable adverse events&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">6</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Few studies describe the type and frequency of adverse events and the errors made in HD units&#46;<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">7&#8211;9</span></a> The majority are based on notification by healthcare personnel&#44; thus requiring a higher degree of involvement in the culture of safety which is not always present&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">To identify the risk areas in HD and understand the prevailing attitudes and concerns&#44; questionnaires have been used which were designed specifically for patients and healthcare professionals&#46; The results of these surveys conclude that&#58; dialysis centres share significant safety risks&#59; patients are more concerned about safety practices than personnel had thought they would&#59; personnel believe units are safer than what the available data actually show&#59; and a specific safety team must be in place to focus on the different risk areas and establish objectives to improve safety&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">10</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Several studies summarise the most common HD safety problems into 5 groups<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">11&#8211;13</span></a>&#58; &#40;1&#41; patient failure&#59; &#40;2&#41; medication errors &#40;including deviation from prescribed dialysis&#44; allergic reactions and omission of medication&#41;&#59; &#40;3&#41; access-related events &#40;coagulation&#44; infiltrates&#44; limited blood flow&#44; difficult cannulation&#41;&#59; &#40;4&#41; technical errors &#40;incorrect dialyser or dialysis fluid and equipment-related sepsis&#41;&#59; and &#40;5&#41; blood loss or prolonged bleeding&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Strategies to prevent errors and adverse events</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Safety culture</span><p id="par0035" class="elsevierStylePara elsevierViewall">The most common causes of safety protocol violation in HD units are unintentional human errors and inadequate communication amongst healthcare personnel&#46; It is therefore crucial to educate healthcare personnel on the culture of safety&#44; so that they understand why these initiatives are necessary and how they can apply them&#46;<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">14</span></a> It is not only important for healthcare professionals to have skills and knowledge based on scientific evidence&#44; but they must also be able to communicate appropriately and know how to act and react in unexpected situations&#44;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">15</span></a> which is a key factor in healthcare safety&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The organisations that have developed a culture of safety generally agree that this has been a key element in achieving their objectives&#46;<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">16</span></a> In fact&#44; the lack of a positive culture towards patient safety favours the onset of adverse events&#44; drug administration errors&#44; patient complaints and more fistula thrombosis incidents&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">17</span></a> Some experiences have shown that hypotension&#44; venous needle disconnection and HD patient failure are associated with an unfavourable environment at work&#46; They also showed that the aspects with the biggest influence on the suitability of this environment were the doctor-nurse relationship&#44; the nurses&#8217; ability to provide healthcare and the quality of nursing care&#46;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">18</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The development of a culture of safety is a structural requirement for creating the conditions that allow personnel to learn from errors and to ensure they are not repeated&#46; However&#44; the results obtained do not provide sufficient evidence of the impact of the procedures for creating a culture of safety&#46; The investigations into the culture of safety have been primarily aimed at evaluating personnel and patient satisfaction and the climate of safety &#40;the personnel&#39;s attitudes and perceptions in this regard&#41;&#44; with less focus being placed on evaluating its association with different clinical results&#46;<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">19&#44;20</span></a> In this sense&#44; several instruments have been developed to measure the degree to which this culture has been implemented&#46; These questionnaires are designed to gain an understanding of the organisations&#8217; specific situation and to identify actions for improvement&#46; One of these questionnaires is created by the Agency for Health Care Research and Quality &#40;<a href="http://www.ahqr.gov/">www&#46;ahqr&#46;gov</a>&#41; and includes several indicators of patient safety&#44; one of which may be related to HD &#40;central venous catheter-related blood infection&#41;&#46; This agency also established a series of 22 safety practices&#58; ten of these are highly recommended&#44; including the real-time use of ultrasound for the placement of central venous catheters&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Coordination and communication amongst different working teams</span><p id="par0050" class="elsevierStylePara elsevierViewall">The collaboration of Hospital Pharmacy and the laboratory&#39;s measurement and incorporation of glomerular filtration rate have been some of the strategies implemented to reduce errors in hospitalised patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0240"><span class="elsevierStyleSup">21&#44;22</span></a> Other experiences have included the implementation of alert systems within the hospital&#44; which recommend adjusting the drug dose depending on the level of renal function during hospitalisation&#46; Furthermore&#44; a consensus guideline for the use of medicinal products in kidney failure has recently been published&#46; The work generating this guideline was funded by the College of Pharmacists of Barcelona &#40;Colegio de Farmac&#233;uticos de Barcelona&#44; 2010&#8211;2011 edition&#41; and the Supervised Traineeship Teaching Unit of Universidad de Barcelona&#46; Besides the obvious benefits of reducing errors&#44; all these actions illustrate the need for appropriate coordination and communication amongst the different teams involved in order to be successful&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Involvement of family members and patients</span><p id="par0055" class="elsevierStylePara elsevierViewall">It is important that the implementation of a safety plan does not only involve the participation of healthcare professionals&#44; but also that of healthy people &#40;family members&#41; and the patients themselves&#58; patient observations and their participation in reducing errors have shown to increase the efficacy of safety efforts&#46;<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">23&#44;24</span></a></p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Information and communication technologies</span><p id="par0060" class="elsevierStylePara elsevierViewall">It is important to recognise the role of information and communication technologies as a tool for reducing errors and improving safety&#46; However they are not effective if they are not implemented correctly because they may even lead to errors &#40;&#8220;e-iatrogenesis&#8221;&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">25</span></a> Another aspect of patient safety is the safety of the information&#46; An organisation that implements a well developed safety policy will have no issues in terms of the safety of the information contained in the patients&#8217; medical records&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">25</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">To reduce adverse events&#44; emphasis needs to be placed on four aspects&#44; which can be summarised as follows&#58; &#40;1&#41; accept that we are fallible and can make mistakes&#59; &#40;2&#41; apply systems for detecting all errors and their causes&#59; &#40;3&#41; design care systems designed to reduce the likelihood of errors&#59; and &#40;4&#41; recognise quickly the emotional problems of those who care for patients&#46;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">26</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">To improve patient safety&#44; the magnitude and characteristics of the clinical risk should be assessed&#59; the factors contributing to the onset of incidents related to patient safety should be understood&#59; an assessment should be made of the impact of adverse effects on patients and the healthcare system&#59; and effective&#44; feasible and sustainable solutions should be identified in order to achieve a safer healthcare provision and prevent incidents and adverse effects&#46;<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">4&#44;27</span></a> Likewise&#44; it is also necessary to assume that actions aimed at attaining optimum conditions&#44; in which risks and errors are reduced to an absolute minimum&#44; should be effectively coordinated with all parties involved&#46; Given that the incorporation of any change is a complicated procedure&#44; such changes must constitute a clear improvement over what it was established&#59; then&#44; the proposed changes will be accepted and fully incorporated into the operating procedures of the organisation and will be recognised by all members&#46;</p></span></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:3 [
          "identificador" => "sec0005"
          "titulo" => "Strategies to prevent errors and adverse events"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "sec0010"
              "titulo" => "Safety culture"
            ]
            1 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Coordination and communication amongst different working teams"
            ]
            2 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Involvement of family members and patients"
            ]
            3 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Information and communication technologies"
            ]
          ]
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Arenas Jim&#233;nez MD&#44; Mac&#237;a-Heras M&#46; Seguridad en hemodi&#225;lisis&#58; paradigma del trabajo en equipo&#46; Nefrologia&#46; 2018&#59;38&#58;1&#8211;3&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:27 [
            0 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "M&#225;s all&#225; de la supervivencia en di&#225;lisis&#44; necesitamos cambiar el paradigma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Mac&#237;a-Heras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3265/Nefrologia.pre2013.Jul.12166"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrolog&#237;a"
                        "fecha" => "2013"
                        "volumen" => "33"
                        "paginaInicial" => "623"
                        "paginaFinal" => "628"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24089153"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patient safety&#58; what is it all about&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Schwappach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000365497"
                      "Revista" => array:6 [
                        "tituloSerie" => "Contrib Nephrol"
                        "fecha" => "2015"
                        "volumen" => "184"
                        "paginaInicial" => "1"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25676288"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessing risk&#58; the role of probabilistic risk assessment &#40;PRA&#41; in patient safety improvement"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Wreathall"
                            1 => "C&#46; Nemeth"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/qhc.13.3.206"
                      "Revista" => array:6 [
                        "tituloSerie" => "Qual Saf Health Care"
                        "fecha" => "2004"
                        "volumen" => "13"
                        "paginaInicial" => "206"
                        "paginaFinal" => "212"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15175492"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical risk analysis with failure mode and effect analysis &#40;FMEA&#41; model in a dialysis unit"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Bonfant"
                            1 => "P&#46; Belfanti"
                            2 => "G&#46; Paternoster"
                            3 => "D&#46; Gabrielli"
                            4 => "A&#46;M&#46; Gaiter"
                            5 => "M&#46; Manes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nephrol"
                        "fecha" => "2010"
                        "volumen" => "23"
                        "paginaInicial" => "111"
                        "paginaFinal" => "118"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20091494"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adverse drug events in hospitalized patients with chronic kidney disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Y&#46; Hassan"
                            1 => "R&#46;J&#46; Al-Ramahi"
                            2 => "N&#46;A&#46; Aziz"
                            3 => "R&#46; Ghazali"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Clin Pharmacol Ther"
                        "fecha" => "2010"
                        "volumen" => "48"
                        "paginaInicial" => "571"
                        "paginaFinal" => "576"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20860910"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "&#91;in Spanish&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Preventable adverse drug events in hospitalized patients&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;J&#46; Otero-L&#243;pez"
                            1 => "P&#46; Alonso-Hern&#225;ndez"
                            2 => "J&#46;A&#46; Maderuelo-Fern&#225;ndez"
                            3 => "B&#46; Garrido-Corro"
                            4 => "A&#46; Dom&#237;nguez-Gil"
                            5 => "A&#46; S&#225;nchez-Rodr&#237;guez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2006"
                        "volumen" => "126"
                        "paginaInicial" => "81"
                        "paginaFinal" => "87"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "&#91;in Spanish&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Analysis of clinical risk and adoption of shared procedures&#58; experience of nephrology and dialysis unit of ASL BA&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Mancini"
                            1 => "P&#46; Angelini"
                            2 => "M&#46; Bozzi"
                            3 => "C&#46; Cuzzola"
                            4 => "V&#46; Giancaspro"
                            5 => "E&#46; Laraia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "G Ital Nefrol"
                        "fecha" => "2015"
                        "paginaInicial" => "32"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Incidencia y tipo de efectos adversos durante el procedimiento de hemodi&#225;lisis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Matar&#225;n Robles"
                            1 => "R&#46; Aguilar Garc&#237;a"
                            2 => "M&#46; Mu&#241;oz Becerra"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Enferm Nefrol"
                        "fecha" => "2013"
                        "volumen" => "16"
                        "paginaInicial" => "36"
                        "paginaFinal" => "40"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A descriptive report of errors and adverse events in chronic hemodialysis units"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;L&#46; Holley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nephrol News Issues"
                        "fecha" => "2006"
                        "volumen" => "20"
                        "paginaInicial" => "57"
                        "paginaFinal" => "58"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17168059"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patient and facility safety in hemodialysis&#58; opportunities and strategies to develop a culture of safety"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Garrick"
                            1 => "A&#46; Kliger"
                            2 => "B&#46; Stefanchik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2215/CJN.06530711"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin J Am Soc Nephrol"
                        "fecha" => "2012"
                        "volumen" => "7"
                        "paginaInicial" => "680"
                        "paginaFinal" => "688"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22282480"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "DeVivo R&#46; National ESRD Patient Safety Initiative&#46; Phase II Report&#46; December 2001&#46; A partnership between&#58; the Renal Physicians Association&#44; the Forum of End Stage Renal Disease Networks&#44; and the National Patient Safety Foundation&#46; Available from&#58; <a href="http://www.renalmd.org/WorkArea/DownloadAsset.aspx?id=515">www&#46;renalmd&#46;org&#47;WorkArea&#47;DownloadAsset&#46;aspx&#63;id&#61;515</a> &#91;accessed 29&#46;12&#46;16&#93;&#46;"
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "p&#46; 87&#8211;96&#46; Available from&#58; <span class="elsevierStyleInterRef" id="intr0020" href="http://patientsafetyauthority.org/ADVISORIES/AdvisoryLibrary/2010/Sep73/Pages/87.aspx">http&#58;&#47;&#47;patientsafetyauthority&#46;org&#47;ADVISORIES&#47;AdvisoryLibrary&#47;2010&#47;Sep73&#47;Pages&#47;87&#46;aspx</span> &#91;accessed 29&#46;12&#46;16&#93;"
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "titulo" => "Hemodialysis Administration Strategies to ensure safe patient care&#46; Pennsylvania Patient Safety Advisory 3&#46; The Pennsylvania Patient Safety Authority"
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:1 [
                        "fecha" => "2010"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "Available from&#58; <span class="elsevierStyleInterRef" id="intr0025" href="http://www.kidneypatientsafety.org/aboutaspx">http&#58;&#47;&#47;www&#46;kidneypatientsafety&#46;org&#47;aboutaspx</span> &#91;accessed 4&#46;6&#46;17&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Health and safety survey to improve patient safety in end stage renal disease&#58; Report of findings from the ESRD patient survey"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "Renal Physicians Association"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:1 [
                        "fecha" => "2007"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Oficina de Planificaci&#243;n Sanitaria y Calidad&#46; Desarrollo de la Estrategia Nacional en Seguridad del Paciente 2015-2020&#46; &#91;Internet&#93; Madrid&#58; Ministerio de Sanidad y Pol&#237;tica Social&#59; Agencia de Calidad del Sistema Nacional de Salud&#46; Aprobado por el Consejo Interterritorial del Sistema Nacional de Salud del di¿a 29 de julio de 2015&#46; Available from&#58; <a href="http://www.seguridaddelpaciente.es/resources/documentos/estrategia_sp_sns_2015_2020.pdf">http&#58;&#47;&#47;www&#46;seguridaddelpaciente&#46;es&#47;resources&#47;documentos&#47;estrategia&#95;sp&#95;sns&#95;2015&#95;2020&#46;pdf</a> &#91;accessed 21&#46;10&#46;16&#93;&#46;"
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An overview on cognitive aspects implicated in medical decisions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Gorini"
                            1 => "G&#46; Pravettoni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ejim.2011.06.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Intern Med"
                        "fecha" => "2011"
                        "volumen" => "22"
                        "paginaInicial" => "547"
                        "paginaFinal" => "553"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22075278"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "Available from&#58; <span class="elsevierStyleInterRef" id="intr0035" href="http://www.jointcommission.org/assets/1/18/tjc-improvingpatientandworkersafety-monograph.pdf">http&#58;&#47;&#47;www&#46;jointcommission&#46;org&#47;assets&#47;1&#47;18&#47;tjc-improvingpatientandworkersafety-monograph&#46;pdf</span> &#91;accessed 25&#46;1&#46;15&#93;"
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "titulo" => "Improving patient and worker safety&#46; Opportunities for sinergy&#44; collaboration and innovation&#46; &#91;Internet&#93;"
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:2 [
                        "fecha" => "2012"
                        "editorial" => "Joint Commission"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patient safety culture and nurse-reported adverse events in outpatient hemodialysis units"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Thomas-Hawkins"
                            1 => "L&#46; Flynn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Res Theory Nurs Pract"
                        "fecha" => "2015"
                        "volumen" => "29"
                        "paginaInicial" => "53"
                        "paginaFinal" => "65"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25799696"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The work environment of haemodialysis nurses and its impact on patients&#8217; outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Prezerakos"
                            1 => "P&#46; Galanis"
                            2 => "I&#46; Moisoglou"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/ijn.12373"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Nurs Pract"
                        "fecha" => "2015"
                        "volumen" => "21"
                        "paginaInicial" => "132"
                        "paginaFinal" => "140"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26125580"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring safety climate&#58; Identifying the common features &#91;Internet&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Flin"
                            1 => "K&#46; Mearns"
                            2 => "P&#46; O&#8217;Connor"
                            3 => "R&#46; Bryden"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Saf Sci"
                        "fecha" => "2000"
                        "volumen" => "34"
                        "paginaInicial" => "177"
                        "paginaFinal" => "192"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Predictors and outcomes of patient safety culture in hospitals"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "F&#46; l-Jardali"
                            1 => "L&#46; Dimassi"
                            2 => "D&#46; Jamai"
                            3 => "M&#46; Jaafar"
                            4 => "N&#46; Hemadeh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Health Serv Res"
                        "fecha" => "2011"
                        "volumen" => "24"
                        "paginaInicial" => "11"
                        "paginaFinal" => "45"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dosing errors in prescribed antibiotics for older persons with CKD&#58; a retrospective time series analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Farag"
                            1 => "A&#46;X&#46; Garg"
                            2 => "L&#46; Li"
                            3 => "A&#46;K&#46; Jain"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/j.ajkd.2013.09.009"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
                        "fecha" => "2014"
                        "volumen" => "63"
                        "paginaInicial" => "422"
                        "paginaFinal" => "428"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24189475"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Medication errors in chronic kidney disease&#58; one piece in the patient safety puzzle"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;C&#46; Fink"
                            1 => "G&#46;M&#46; Chertow"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/ki.2009.315"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2009"
                        "volumen" => "76"
                        "paginaInicial" => "1123"
                        "paginaFinal" => "1125"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19910946"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maintaining safety in the dialysis facility"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;S&#46; Kliger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2215/CJN.08960914"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin J Am Soc Nephrol"
                        "fecha" => "2015"
                        "volumen" => "10"
                        "paginaInicial" => "688"
                        "paginaFinal" => "695"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25376767"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Key points for patient safety in dialysis access"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;K&#46; Widmer"
                            1 => "D&#46; Schwappach"
                            2 => "J&#46; Schmidli"
                            3 => "T&#46;R&#46; Wyss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5301/jva.5000375"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Vasc Access"
                        "fecha" => "2015"
                        "volumen" => "16"
                        "numero" => "Suppl 9"
                        "paginaInicial" => "S114"
                        "paginaFinal" => "S117"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25751564"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "XI informe SEIS &#40;Sociedad Espa&#241;ola de Inform&#225;tica de la Salud&#41;&#58; Las TIC y la seguridad de los pacientes &#40;primum non nocere&#41;&#46; Carnicero Gim&#233;nez de Azc&#225;rate J&#44; Rojas de la Escalera D&#44; Mart&#237;nez Santiago R&#44; &#40;coords&#41;&#59; 2016&#46; Available from&#58; <a href="http://www.seis.es/Informes.html">http&#58;&#47;&#47;www&#46;seis&#46;es&#47;Informes&#46;html</a> &#91;accessed 3&#46;6&#46;17&#93;&#46;"
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dialysis facility safety&#58; processes and opportunities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Garrick"
                            1 => "R&#46; Morey"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/sdi.12395"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Dial"
                        "fecha" => "2015"
                        "volumen" => "28"
                        "paginaInicial" => "514"
                        "paginaFinal" => "524"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26073909"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La investigaci&#243;n sobre seguridad del paciente&#58; necesidades y perspectivas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Aibar-Rem&#243;na"
                            1 => "J&#46;M&#46; Aranaz-Andr&#233;s"
                            2 => "J&#46;L&#46; Garc&#237;a-Monteroc"
                            3 => "R&#46; Mareca-Do&#241;atea"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2008"
                        "volumen" => "131"
                        "numero" => "Supl 3"
                        "paginaInicial" => "12"
                        "paginaFinal" => "17"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003800000001/v1_201802180616/S2013251418300178/v1_201802180616/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35429"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Editorials"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003800000001/v1_201802180616/S2013251418300178/v1_201802180616/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251418300178?idApp=UINPBA000064"
]
Share
Journal Information
Vol. 38. Issue. 1.January - February 2018
Pages 1-108
Vol. 38. Issue. 1.January - February 2018
Pages 1-108
Editorial
Open Access
Safety on haemodialysis: Team work paradigm
Seguridad en hemodiálisis: paradigma del trabajo en equipo
Visits
8896
Maria Dolores Arenas Jiméneza,
Corresponding author
lola@olemiswebs.com

Corresponding author.
, Manuel Macía-Herasb
a Servicio de Nefrología, Vithas Hospital Perpetuo Internacional, Alicante, Spain
b Servicio de Nefrología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain
This item has received

Under a Creative Commons license
Article information
Full Text
Bibliography
Download PDF
Statistics
Full Text

Safety in healthcare is the absence or the reduction to a minimum acceptable risk of unnecessary harm during the provision of healthcare (source: AMSP/WHO: International Classification for Patient Safety).

Haemodialysis (HD) entails a series of procedures and techniques, some of which are complex, involving cutting-edge technology (water treatment, monitors, etc.), the administration of medicinal products and pharmacovigilance. All this occurs in fragile elderly patients with many comorbidities, who make use of healthcare systems in an intense and fragmented fashion, meaning they are at an increased risk of suffering from significant effects.1,2 The likelihood of errors is therefore higher,3 so it is necessary to establish prevention strategies for healthcare-related adverse events. This should be done through a prioritisation system, in accordance with their frequency, severity of the effects and how detectable they are.4 Only close observation of the procedures can guarantee high quality healthcare with better clinical results, fewer complications, the elimination of inadequate procedures and greater patient satisfaction.

The most commonly reported adverse events in kidney diseases occur in hospitalised patients. These include medication errors of up to 40.7%, of which 30.2% were considered avoidable.5 Overall, inadequate monitoring (28.3%), excessive dosing (21.7%), selection of an inadequate drug (15.0%), failure to prescribe the required drug (15.0%) and drug interactions (11.7%) are the most common errors causing avoidable adverse events.6

Few studies describe the type and frequency of adverse events and the errors made in HD units.7–9 The majority are based on notification by healthcare personnel, thus requiring a higher degree of involvement in the culture of safety which is not always present.

To identify the risk areas in HD and understand the prevailing attitudes and concerns, questionnaires have been used which were designed specifically for patients and healthcare professionals. The results of these surveys conclude that: dialysis centres share significant safety risks; patients are more concerned about safety practices than personnel had thought they would; personnel believe units are safer than what the available data actually show; and a specific safety team must be in place to focus on the different risk areas and establish objectives to improve safety.10

Several studies summarise the most common HD safety problems into 5 groups11–13: (1) patient failure; (2) medication errors (including deviation from prescribed dialysis, allergic reactions and omission of medication); (3) access-related events (coagulation, infiltrates, limited blood flow, difficult cannulation); (4) technical errors (incorrect dialyser or dialysis fluid and equipment-related sepsis); and (5) blood loss or prolonged bleeding.

Strategies to prevent errors and adverse eventsSafety culture

The most common causes of safety protocol violation in HD units are unintentional human errors and inadequate communication amongst healthcare personnel. It is therefore crucial to educate healthcare personnel on the culture of safety, so that they understand why these initiatives are necessary and how they can apply them.14 It is not only important for healthcare professionals to have skills and knowledge based on scientific evidence, but they must also be able to communicate appropriately and know how to act and react in unexpected situations,15 which is a key factor in healthcare safety.

The organisations that have developed a culture of safety generally agree that this has been a key element in achieving their objectives.16 In fact, the lack of a positive culture towards patient safety favours the onset of adverse events, drug administration errors, patient complaints and more fistula thrombosis incidents.17 Some experiences have shown that hypotension, venous needle disconnection and HD patient failure are associated with an unfavourable environment at work. They also showed that the aspects with the biggest influence on the suitability of this environment were the doctor-nurse relationship, the nurses’ ability to provide healthcare and the quality of nursing care.18

The development of a culture of safety is a structural requirement for creating the conditions that allow personnel to learn from errors and to ensure they are not repeated. However, the results obtained do not provide sufficient evidence of the impact of the procedures for creating a culture of safety. The investigations into the culture of safety have been primarily aimed at evaluating personnel and patient satisfaction and the climate of safety (the personnel's attitudes and perceptions in this regard), with less focus being placed on evaluating its association with different clinical results.19,20 In this sense, several instruments have been developed to measure the degree to which this culture has been implemented. These questionnaires are designed to gain an understanding of the organisations’ specific situation and to identify actions for improvement. One of these questionnaires is created by the Agency for Health Care Research and Quality (www.ahqr.gov) and includes several indicators of patient safety, one of which may be related to HD (central venous catheter-related blood infection). This agency also established a series of 22 safety practices: ten of these are highly recommended, including the real-time use of ultrasound for the placement of central venous catheters.

Coordination and communication amongst different working teams

The collaboration of Hospital Pharmacy and the laboratory's measurement and incorporation of glomerular filtration rate have been some of the strategies implemented to reduce errors in hospitalised patients.21,22 Other experiences have included the implementation of alert systems within the hospital, which recommend adjusting the drug dose depending on the level of renal function during hospitalisation. Furthermore, a consensus guideline for the use of medicinal products in kidney failure has recently been published. The work generating this guideline was funded by the College of Pharmacists of Barcelona (Colegio de Farmacéuticos de Barcelona, 2010–2011 edition) and the Supervised Traineeship Teaching Unit of Universidad de Barcelona. Besides the obvious benefits of reducing errors, all these actions illustrate the need for appropriate coordination and communication amongst the different teams involved in order to be successful.

Involvement of family members and patients

It is important that the implementation of a safety plan does not only involve the participation of healthcare professionals, but also that of healthy people (family members) and the patients themselves: patient observations and their participation in reducing errors have shown to increase the efficacy of safety efforts.23,24

Information and communication technologies

It is important to recognise the role of information and communication technologies as a tool for reducing errors and improving safety. However they are not effective if they are not implemented correctly because they may even lead to errors (“e-iatrogenesis”).25 Another aspect of patient safety is the safety of the information. An organisation that implements a well developed safety policy will have no issues in terms of the safety of the information contained in the patients’ medical records.25

To reduce adverse events, emphasis needs to be placed on four aspects, which can be summarised as follows: (1) accept that we are fallible and can make mistakes; (2) apply systems for detecting all errors and their causes; (3) design care systems designed to reduce the likelihood of errors; and (4) recognise quickly the emotional problems of those who care for patients.26

To improve patient safety, the magnitude and characteristics of the clinical risk should be assessed; the factors contributing to the onset of incidents related to patient safety should be understood; an assessment should be made of the impact of adverse effects on patients and the healthcare system; and effective, feasible and sustainable solutions should be identified in order to achieve a safer healthcare provision and prevent incidents and adverse effects.4,27 Likewise, it is also necessary to assume that actions aimed at attaining optimum conditions, in which risks and errors are reduced to an absolute minimum, should be effectively coordinated with all parties involved. Given that the incorporation of any change is a complicated procedure, such changes must constitute a clear improvement over what it was established; then, the proposed changes will be accepted and fully incorporated into the operating procedures of the organisation and will be recognised by all members.

References
[1]
M. Macía-Heras.
Más allá de la supervivencia en diálisis, necesitamos cambiar el paradigma.
[2]
D. Schwappach.
Patient safety: what is it all about?.
Contrib Nephrol, 184 (2015), pp. 1-12
[3]
J. Wreathall, C. Nemeth.
Assessing risk: the role of probabilistic risk assessment (PRA) in patient safety improvement.
Qual Saf Health Care, 13 (2004), pp. 206-212
[4]
G. Bonfant, P. Belfanti, G. Paternoster, D. Gabrielli, A.M. Gaiter, M. Manes, et al.
Clinical risk analysis with failure mode and effect analysis (FMEA) model in a dialysis unit.
J Nephrol, 23 (2010), pp. 111-118
[5]
Y. Hassan, R.J. Al-Ramahi, N.A. Aziz, R. Ghazali.
Adverse drug events in hospitalized patients with chronic kidney disease.
Int J Clin Pharmacol Ther, 48 (2010), pp. 571-576
[6]
M.J. Otero-López, P. Alonso-Hernández, J.A. Maderuelo-Fernández, B. Garrido-Corro, A. Domínguez-Gil, A. Sánchez-Rodríguez.
[Preventable adverse drug events in hospitalized patients].
Med Clin (Barc), 126 (2006), pp. 81-87
[in Spanish]
[7]
A. Mancini, P. Angelini, M. Bozzi, C. Cuzzola, V. Giancaspro, E. Laraia, et al.
[Analysis of clinical risk and adoption of shared procedures: experience of nephrology and dialysis unit of ASL BA].
G Ital Nefrol, (2015), pp. 32
[in Spanish]
[8]
M. Matarán Robles, R. Aguilar García, M. Muñoz Becerra.
Incidencia y tipo de efectos adversos durante el procedimiento de hemodiálisis.
Enferm Nefrol, 16 (2013), pp. 36-40
[9]
J.L. Holley.
A descriptive report of errors and adverse events in chronic hemodialysis units.
Nephrol News Issues, 20 (2006), pp. 57-58
[10]
R. Garrick, A. Kliger, B. Stefanchik.
Patient and facility safety in hemodialysis: opportunities and strategies to develop a culture of safety.
Clin J Am Soc Nephrol, 7 (2012), pp. 680-688
[11]
DeVivo R. National ESRD Patient Safety Initiative. Phase II Report. December 2001. A partnership between: the Renal Physicians Association, the Forum of End Stage Renal Disease Networks, and the National Patient Safety Foundation. Available from: www.renalmd.org/WorkArea/DownloadAsset.aspx?id=515 [accessed 29.12.16].
[12]
Hemodialysis Administration Strategies to ensure safe patient care. Pennsylvania Patient Safety Advisory 3. The Pennsylvania Patient Safety Authority.
(2010),
p. 87–96. Available from: http://patientsafetyauthority.org/ADVISORIES/AdvisoryLibrary/2010/Sep73/Pages/87.aspx [accessed 29.12.16]
[13]
Renal Physicians Association.
Health and safety survey to improve patient safety in end stage renal disease: Report of findings from the ESRD patient survey.
(2007),
Available from: http://www.kidneypatientsafety.org/aboutaspx [accessed 4.6.17]
[14]
Oficina de Planificación Sanitaria y Calidad. Desarrollo de la Estrategia Nacional en Seguridad del Paciente 2015-2020. [Internet] Madrid: Ministerio de Sanidad y Política Social; Agencia de Calidad del Sistema Nacional de Salud. Aprobado por el Consejo Interterritorial del Sistema Nacional de Salud del di¿a 29 de julio de 2015. Available from: http://www.seguridaddelpaciente.es/resources/documentos/estrategia_sp_sns_2015_2020.pdf [accessed 21.10.16].
[15]
A. Gorini, G. Pravettoni.
An overview on cognitive aspects implicated in medical decisions.
Eur J Intern Med, 22 (2011), pp. 547-553
[16]
Improving patient and worker safety. Opportunities for sinergy, collaboration and innovation. [Internet].
Joint Commission, (2012),
Available from: http://www.jointcommission.org/assets/1/18/tjc-improvingpatientandworkersafety-monograph.pdf [accessed 25.1.15]
[17]
C. Thomas-Hawkins, L. Flynn.
Patient safety culture and nurse-reported adverse events in outpatient hemodialysis units.
Res Theory Nurs Pract, 29 (2015), pp. 53-65
[18]
P. Prezerakos, P. Galanis, I. Moisoglou.
The work environment of haemodialysis nurses and its impact on patients’ outcomes.
Int J Nurs Pract, 21 (2015), pp. 132-140
[19]
R. Flin, K. Mearns, P. O’Connor, R. Bryden.
Measuring safety climate: Identifying the common features [Internet].
Saf Sci, 34 (2000), pp. 177-192
[20]
F. l-Jardali, L. Dimassi, D. Jamai, M. Jaafar, N. Hemadeh.
Predictors and outcomes of patient safety culture in hospitals.
BMC Health Serv Res, 24 (2011), pp. 11-45
[21]
A. Farag, A.X. Garg, L. Li, A.K. Jain.
Dosing errors in prescribed antibiotics for older persons with CKD: a retrospective time series analysis.
Am J Kidney Dis, 63 (2014), pp. 422-428
[22]
J.C. Fink, G.M. Chertow.
Medication errors in chronic kidney disease: one piece in the patient safety puzzle.
Kidney Int, 76 (2009), pp. 1123-1125
[23]
A.S. Kliger.
Maintaining safety in the dialysis facility.
Clin J Am Soc Nephrol, 10 (2015), pp. 688-695
[24]
M.K. Widmer, D. Schwappach, J. Schmidli, T.R. Wyss.
Key points for patient safety in dialysis access.
J Vasc Access, 16 (2015), pp. S114-S117
[25]
XI informe SEIS (Sociedad Española de Informática de la Salud): Las TIC y la seguridad de los pacientes (primum non nocere). Carnicero Giménez de Azcárate J, Rojas de la Escalera D, Martínez Santiago R, (coords); 2016. Available from: http://www.seis.es/Informes.html [accessed 3.6.17].
[26]
R. Garrick, R. Morey.
Dialysis facility safety: processes and opportunities.
Semin Dial, 28 (2015), pp. 514-524
[27]
C. Aibar-Remóna, J.M. Aranaz-Andrés, J.L. García-Monteroc, R. Mareca-Doñatea.
La investigación sobre seguridad del paciente: necesidades y perspectivas.
Med Clin (Barc), 131 (2008), pp. 12-17

Please cite this article as: Arenas Jiménez MD, Macía-Heras M. Seguridad en hemodiálisis: paradigma del trabajo en equipo. Nefrologia. 2018;38:1–3.

Copyright © 2017. Sociedad Española de Nefrología
Download PDF
Idiomas
Nefrología (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?