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Coronary artery calcification is more frequent, more extensive and progresses more rapidly in CKD than in general population. They are also considered a marker of coronary heart disease, with high prevalence and functional significance. It suggests that detection and surveillance may be worthwhile in general clinical practice. New non-invasive image techniques, like Multi-detector row CT, a type of spiral scanner, assess density and volume of calcification at multiple sites and allow quantitative scoring of vascular calcification using calcium scores analogous to those from electron-beam CT. We have assessed and quantified coronary artery calcification with 16 multidetector row CT in 44 patients on hemodialysis and their relationship with several cardiovascular risk factors. Coronary artery calcification prevalence was of 84 % with mean calcium score of 1580 ± 2010 ( r 0-9844) with calcium score > 400 in 66% of patients. It was usually multiple, affecting more than two vessels in more than 50%. In all but one patient, left anterior descending artery was involved with higher calcium score level at right coronary artery. Advanced age, male, diabetes, smoking, more morbidity, cerebrovascular disease previous, and calcium-binders phosphate and analogous vitamin D treatment would seem to be associated with coronary artery calcification. Coronary artery calcification is very frequent and extensive, usually multiple and associated to modifiable risk factors in hemodialysis patients. Multi-detector-row CT seems an effective, suitable, readily applicable method to assess and quantify coronary artery calcification. " ] "es" => array:1 [ "resumen" => "lobal. Las calcificaciones de las arterias coronarias en pacientes renales son más frecuentes, más extensas y progresan más rápidamente que en la población general y constituyen un marcador de enfermedad coronaria de elevada prevalencia y significación funcional. La aparición de nuevas técnicas de imagen, como el TAC multidetector, permiten detectar y cuantificar las calcificaciones vasculares utilizando un score de calcificación similar al score de calcio del TAC emisor de electrones. Mediante TAC helicoidal de 16 filas de detectores hemos evaluado y cuantificado la presencia de calcificación de arterias coronarias y su relación con diferentes factores de riesgo cardiovascular en 44 pacientes en hemodiálisis. La prevalencia de calcificación fue del 84%, con un score de calcio medio de 1.580 ± 2.010 (r 0-9.844). El 66% de los pacientes presentaban valores de score de calcio > 400. La calcificación coronaria era por lo general múltiple, afectando a más de 2 vasos y de manera prácticamente constante a la arteria descendente anterior (97%) aunque la arteria coronaria derecha presentó valores de score de calcio más elevados. La calcificación coronaria se relacionó con edad avanzada, sexo masculino, diabetes, mayor comorbilidad, tabaquismo, antecedentes de enfermedad cerebrovascular y tratamiento con quelantes del fósforo que contenían calcio y análogos de la vitamina D. La calcificación de las arterias coronarias es muy frecuente y extensa, normalmente múltiple y asociada a factores de riesgo cardiovascular modificables en los pacientes en hemodiálisis. El TAC Multidetector parece un método eficaz, fácil de reproducir y cómodo para el paciente que permite detectar y cuantificar las calcificaciones coronarias." ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002700000006/v0_201502091551/X2013251407022157/v0_201502091551/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002700000006/v0_201502091551/X2013251407022157/v0_201502091551/en/P-E-S-A4648-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251407022157?idApp=UINPBA000064" ]
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Multidetector Row CT in assessment of coronary artery calcification on hemodialisis
Valoración de las calcificaciones coronarias
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Pilar Caro Acevedo, Ramon Delgado Lillo, Fabiola Dapena Vielba, Almudena Njuñez Sanchez
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SUMMARY Vascular calcification is a strong predictor of cardiovascular and all-cause mortality. Coronary artery calcification is more frequent, more extensive and progresses more rapidly in CKD than in general population. They are also considered a marker of coronary heart disease, with high prevalence and functional significance. It suggests that detection and surveillance may be worthwhile in general clinical practice. New non-invasive image techniques, like Multi-detector row CT, a type of spiral scanner, assess density and volume of calcification at multiple sites and allow quantitative scoring of vascular calcification using calcium scores analogous to those from electron-beam CT. We have assessed and quantified coronary artery calcification with 16 multidetector row CT in 44 patients on hemodialysis and their relationship with several cardiovascular risk factors. Coronary artery calcification prevalence was of 84 % with mean calcium score of 1580 ± 2010 ( r 0-9844) with calcium score > 400 in 66% of patients. It was usually multiple, affecting more than two vessels in more than 50%. In all but one patient, left anterior descending artery was involved with higher calcium score level at right coronary artery. Advanced age, male, diabetes, smoking, more morbidity, cerebrovascular disease previous, and calcium-binders phosphate and analogous vitamin D treatment would seem to be associated with coronary artery calcification. Coronary artery calcification is very frequent and extensive, usually multiple and associated to modifiable risk factors in hemodialysis patients. Multi-detector-row CT seems an effective, suitable, readily applicable method to assess and quantify coronary artery calcification.
Keywords:
Key words: Coronary artery calcification, Multidetector row CT, calcium score, cardiovascular disease, hemodialysis
lobal. Las calcificaciones de las arterias coronarias en pacientes renales son más frecuentes, más extensas y progresan más rápidamente que en la población general y constituyen un marcador de enfermedad coronaria de elevada prevalencia y significación funcional. La aparición de nuevas técnicas de imagen, como el TAC multidetector, permiten detectar y cuantificar las calcificaciones vasculares utilizando un score de calcificación similar al score de calcio del TAC emisor de electrones. Mediante TAC helicoidal de 16 filas de detectores hemos evaluado y cuantificado la presencia de calcificación de arterias coronarias y su relación con diferentes factores de riesgo cardiovascular en 44 pacientes en hemodiálisis. La prevalencia de calcificación fue del 84%, con un score de calcio medio de 1.580 ± 2.010 (r 0-9.844). El 66% de los pacientes presentaban valores de score de calcio > 400. La calcificación coronaria era por lo general múltiple, afectando a más de 2 vasos y de manera prácticamente constante a la arteria descendente anterior (97%) aunque la arteria coronaria derecha presentó valores de score de calcio más elevados. La calcificación coronaria se relacionó con edad avanzada, sexo masculino, diabetes, mayor comorbilidad, tabaquismo, antecedentes de enfermedad cerebrovascular y tratamiento con quelantes del fósforo que contenían calcio y análogos de la vitamina D. La calcificación de las arterias coronarias es muy frecuente y extensa, normalmente múltiple y asociada a factores de riesgo cardiovascular modificables en los pacientes en hemodiálisis. El TAC Multidetector parece un método eficaz, fácil de reproducir y cómodo para el paciente que permite detectar y cuantificar las calcificaciones coronarias.
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Palabras clave: Calcificación coronaria, TAC multidetector, score de calcio, enfermedad cardiovascular, hemodiálisis
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