array:21 [
  "pii" => "X2013251412001806"
  "issn" => "20132514"
  "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
  "estado" => "S300"
  "fechaPublicacion" => "2012-09-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia (English Version). 2012;32:682"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3677
    "formatos" => array:3 [
      "EPUB" => 313
      "HTML" => 2793
      "PDF" => 571
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699512001809"
      "issn" => "02116995"
      "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
      "estado" => "S300"
      "fechaPublicacion" => "2012-09-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2012;32:682"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6708
        "formatos" => array:3 [
          "EPUB" => 318
          "HTML" => 5810
          "PDF" => 580
        ]
      ]
      "es" => array:9 [
        "idiomaDefecto" => true
        "titulo" => "Insuficiencia renal crónica y enfermedad arterial periférica"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "682"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Chronic renal failure and peripheral arterial disease"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Santiago Suria-González, Noemí Esparza-Martín, Pablo Braillard-Poccard, Antonio Calderín-Ortega, M. Dolores Checa-Andrés"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Santiago"
                "apellidos" => "Suria-González"
              ]
              1 => array:2 [
                "nombre" => "Noemí"
                "apellidos" => "Esparza-Martín"
              ]
              2 => array:2 [
                "nombre" => "Pablo"
                "apellidos" => "Braillard-Poccard"
              ]
              3 => array:2 [
                "nombre" => "Antonio"
                "apellidos" => "Calderín-Ortega"
              ]
              4 => array:2 [
                "nombre" => "M. Dolores"
                "apellidos" => "Checa-Andrés"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251412001806"
          "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001806?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001809?idApp=UINPBA000064"
      "url" => "/02116995/0000003200000005/v0_201502091343/X0211699512001809/v0_201502091344/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251412001791"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.pre2012.Jun.11508"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2012;32:683-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5418
      "formatos" => array:3 [
        "EPUB" => 304
        "HTML" => 4498
        "PDF" => 616
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Disseminated histoplasmosis and haemophagocytic syndrome in two kidney transplant patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "683"
          "paginaFinal" => "684"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Histoplasmosis diseminada y síndrome hemofagocítico en dos pacientes trasplantados renales"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier España"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "11508_16025_36073_en_t111508.jpg"
              "Alto" => 531
              "Ancho" => 1442
              "Tamanyo" => 279620
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Diagnostic criteria for haemophagocytic syndrome"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jhon F. Nieto-Ríos, Arbey Aristizabal-Alzate, Catalina Ocampo, Ana K. Serrano-Gayubo, Lina M. Serna-Higuita, Gustavo Zuluaga-Valencia"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Jhon F."
              "apellidos" => "Nieto-Ríos"
            ]
            1 => array:2 [
              "nombre" => "Arbey"
              "apellidos" => "Aristizabal-Alzate"
            ]
            2 => array:2 [
              "nombre" => "Catalina"
              "apellidos" => "Ocampo"
            ]
            3 => array:2 [
              "nombre" => "Ana K."
              "apellidos" => "Serrano-Gayubo"
            ]
            4 => array:2 [
              "nombre" => "Lina M."
              "apellidos" => "Serna-Higuita"
            ]
            5 => array:2 [
              "nombre" => "Gustavo"
              "apellidos" => "Zuluaga-Valencia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699512001794"
        "doi" => "10.3265/Nefrologia.pre2012.Jun.11508"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001794?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001791?idApp=UINPBA000064"
    "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001791/v0_201502091606/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251412001814"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.pre2012.Jun.11528"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2012;32:680-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3755
      "formatos" => array:3 [
        "EPUB" => 303
        "HTML" => 2947
        "PDF" => 505
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "On-Line haemodialfiltration versus high flux haemodialysis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "680"
          "paginaFinal" => "682"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Hemodiafiltración on-line frente a hemodiálisis de alto flujo"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier España"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "11528_16025_36080_en_t111528.jpg"
              "Alto" => 517
              "Ancho" => 1443
              "Tamanyo" => 284388
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Patient Data"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Antonio Gomis-Couto, Sandra Elías, Milagros Fernández-Lucas, Gloria Ruiz-Roso, Martha Díaz-Domínguez, José L. Teruel, Carlos Quereda"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Antonio"
              "apellidos" => "Gomis-Couto"
            ]
            1 => array:2 [
              "nombre" => "Sandra"
              "apellidos" => "Elías"
            ]
            2 => array:2 [
              "nombre" => "Milagros"
              "apellidos" => "Fernández-Lucas"
            ]
            3 => array:2 [
              "nombre" => "Gloria"
              "apellidos" => "Ruiz-Roso"
            ]
            4 => array:2 [
              "nombre" => "Martha"
              "apellidos" => "Díaz-Domínguez"
            ]
            5 => array:2 [
              "nombre" => "José L."
              "apellidos" => "Teruel"
            ]
            6 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Quereda"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699512001817"
        "doi" => "10.3265/Nefrologia.pre2012.Jun.11528"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001817?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001814?idApp=UINPBA000064"
    "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001814/v0_201502091606/en/main.assets"
  ]
  "en" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Chronic renal failure and peripheral arterial disease"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "682"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Santiago Suria-González, Noemí Esparza-Martín, Pablo Braillard-Poccard, Antonio Calderín-Ortega, M. Dolores Checa-Andrés"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Santiago"
            "apellidos" => "Suria-González"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Noem&#237;"
            "apellidos" => "Esparza-Mart&#237;n"
            "email" => array:1 [
              0 => "noemiesparza&#64;telefonica&#46;net"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Pablo"
            "apellidos" => "Braillard-Poccard"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Antonio"
            "apellidos" => "Calder&#237;n-Ortega"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "affb"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "M&#46; Dolores"
            "apellidos" => "Checa-Andr&#233;s"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria   "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Angiología y Cirugía Vascular, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria   "
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "affb"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Insuficiencia renal cr&#243;nica y enfermedad arterial perif&#233;rica"
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">To the Editor&#58;</span></p><p class="elsevierStylePara">It has been well established that both patients with chronic renal failure &#40;CRF&#41; and those with peripheral arterial disease &#40;PAD&#41; have increased the risk of death due to cardiovascular disease&#46; Red blood cell distribution width &#40;RDW&#41; is a marker for mortality in patients with established cardiovascular disease&#46; It has been demonstrated that for every 1&#37; increase in RDW&#44; the risk of death increases by 14&#37;&#46;<span class="elsevierStyleSup">1</span> Increased levels of N-terminal pro-brain natriuretic peptide &#40;NT-proBNP&#41; are also associated with increased cardiovascular mortality and morbidity rates in the general population&#46;<span class="elsevierStyleSup">2</span> With this in mind&#44; we sought to evaluate RDW percentage and NT-proBNP levels in patients with peripheral arterial disease &#40;PAD&#41; with or without CRF&#46;</p><p class="elsevierStylePara">We performed a cross-sectional observational study involving 40 patients with PAD &#40;all in stage III or IV on the Fontaine scale&#41;&#44; with no signs of heart failure&#46; Of these&#44; 17 had CRF and 23 did not&#44; 33 were male and 7 were female&#44; and the mean age was 68&#46;03&#177;11&#46;10&#46; The patients were evaluated upon admission to the vascular surgery department&#46; After signing an informed consent form &#40;study approved by the ethics committee&#41;&#44; we compiled clinical&#44; pharmacological&#44; and laboratory values for each patient&#46; NT-proBNP was measured using a solid phase radial partition immunoassay &#40;Acute Care<span class="elsevierStyleSup">&#174; </span>for Stratus<span class="elsevierStyleSup">&#174;</span> CS&#44; Siemens&#41;&#46; Statistical analyses were performed using SPSS statistical software&#44; version 15&#46;0&#46;</p><p class="elsevierStylePara">The 40 patients with PAD had the following mean values&#58; body mass index&#58; 26&#46;32&#177;4&#46;71kg&#47;m<span class="elsevierStyleSup">2</span>&#59; systolic blood pressure&#58; 133&#46;82&#177;19&#46;10mm Hg&#59; diastolic blood pressure&#58; 75&#46;78&#177;11&#46;30mm Hg&#59; and heart rate&#58; 78&#46;18&#177;10&#46;95bpm&#46; Fifty percent of the patients were active smokers&#44; 82&#46;5&#37; were ex-smokers&#44; 27 were diabetics&#44; and 27 had hypertension&#46; Upon dividing the patients based on the presence or absence of CRF&#44; we found that patients with an MDRD4 score &#60;60ml&#47;min &#40;mean&#58; 41&#46;57&#177;11&#46;38ml&#47;min&#41; were older &#40;73&#46;75&#177;10&#46;84 years vs 63&#46;87&#177;9&#46;51 years&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;007&#41;&#44; more prone to hypertension &#40;88&#46;23&#37; vs 57&#46;14&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;02&#41;&#44; and received treatment with beta blockers &#40;52&#46;94&#37; vs 21&#46;74&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;041&#41; and angiotensin II receptor blockers &#40;ARBs&#41; &#40;35&#46;29&#37; vs 21&#46;74&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;038&#41; at a greater rate than patients with an MDRD4&#62;60ml&#47;min &#40;81&#46;54&#177;20&#46;90ml&#47;min&#41;&#44; with no other differences found in terms of drugs administered&#46; There were also no differences in terms of sex distribution&#44; frequency of diabetes&#44; or tobacco use between these two sub-groups&#46; As regards the objectives of our study&#44; we found that patients with CRF had higher levels of NT-proBNP &#40;2561&#46;18&#177;2526&#46;95mg&#47;dl vs&#46; 805&#46;48&#177;1036&#46;02mg&#47;dl&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;01&#41; and a higher RDW percentage &#40;15&#46;54&#177;2&#46;27&#37; vs 14&#46;74&#177;2&#46;11&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;044&#41; than patients with PAD and without CRF&#46; The percentage of RDW was positively correlated with NT-proBNP levels &#40;r&#61;0&#46;56&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;001&#41;&#46;</p><p class="elsevierStylePara">Based on these results&#44; and despite the small number of patients examined&#44; we could affirm that patients with PAD and CRF have higher levels of biological markers of morbidity&#47;mortality than those with PAD and without CRF&#44; which would imply a greater associated cardiovascular risk and perioperative risk<span class="elsevierStyleSup">3</span> than in patients without CRF&#46;<span class="elsevierStyleSup">3</span> The finding of a positive correlation between RDW and NT-proBNP in these patients could suggest a possible association with cardiorenal syndrome&#46; Further studies with more patients could affirm whether patients with PAD treated with beta blockers or ARBs have a higher rate of CRF&#46;</p><p class="elsevierStylePara">&#160;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">Conflicts of interest</span></p><p class="elsevierStylePara">&#160;</p><p class="elsevierStylePara">The authors have no conflicts of interest to declare&#46;</p>"
    "pdfFichero" => "P1-E543-S3702-A11569-EN.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Patel KV,\u{A0}Ferrucci L,\u{A0}Ershler WB,\u{A0}Longo DL,\u{A0}Guralnik JM.\u{A0}Red Cell Distribution Width and the Risk of Death in Middle-aged and Older Adults. Arch Intern Med 2009;169(5):515-23. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19273783" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Daniels LB. Natriuretic Peptides and Assessment of Cardiovascular Disease Risk in Asymptomatic Persons. Curr Cardiovasc Risk Rep 2010;4(2):120-7."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Wazni OM, Martin DO, Marrouche NF, Latif AA, Ziada K, Shaaraoui M, et al. Plasma B-type natriuretic peptide levels predict postoperative atrial fibrillation in patients undergoing cardiac surgery. Circulation 2004;110:124-7. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15210589" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001806/v0_201502091606/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35438"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor - Brief papers about basic research or clinical experiences"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003200000005/v0_201502091606/X2013251412001806/v0_201502091606/en/P1-E543-S3702-A11569-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001806?idApp=UINPBA000064"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Chronic renal failure and peripheral arterial disease
Insuficiencia renal crónica y enfermedad arterial periférica
Santiago Suria-Gonzáleza, Noemí Esparza-Martína, Pablo Braillard-Poccarda, Antonio Calderín-Ortegab, M. Dolores Checa-Andrésa
a Servicio de Nefrología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria
b Servicio de Angiología y Cirugía Vascular, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria
Read
6889
Times
was read the article
2141
Total PDF
4748
Total HTML
Share statistics
 array:21 [
  "pii" => "X2013251412001806"
  "issn" => "20132514"
  "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
  "estado" => "S300"
  "fechaPublicacion" => "2012-09-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia &#40;English Version&#41;. 2012;32:682"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3677
    "formatos" => array:3 [
      "EPUB" => 313
      "HTML" => 2793
      "PDF" => 571
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699512001809"
      "issn" => "02116995"
      "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
      "estado" => "S300"
      "fechaPublicacion" => "2012-09-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2012;32:682"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6708
        "formatos" => array:3 [
          "EPUB" => 318
          "HTML" => 5810
          "PDF" => 580
        ]
      ]
      "es" => array:9 [
        "idiomaDefecto" => true
        "titulo" => "Insuficiencia renal cr&#243;nica y enfermedad arterial perif&#233;rica"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "682"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Chronic renal failure and peripheral arterial disease"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Santiago Suria-Gonz&#225;lez, Noem&#237; Esparza-Mart&#237;n, Pablo Braillard-Poccard, Antonio Calder&#237;n-Ortega, M&#46; Dolores Checa-Andr&#233;s"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Santiago"
                "apellidos" => "Suria-Gonz&#225;lez"
              ]
              1 => array:2 [
                "nombre" => "Noem&#237;"
                "apellidos" => "Esparza-Mart&#237;n"
              ]
              2 => array:2 [
                "nombre" => "Pablo"
                "apellidos" => "Braillard-Poccard"
              ]
              3 => array:2 [
                "nombre" => "Antonio"
                "apellidos" => "Calder&#237;n-Ortega"
              ]
              4 => array:2 [
                "nombre" => "M&#46; Dolores"
                "apellidos" => "Checa-Andr&#233;s"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251412001806"
          "doi" => "10.3265/Nefrologia.pre2012.Jun.11569"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001806?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001809?idApp=UINPBA000064"
      "url" => "/02116995/0000003200000005/v0_201502091343/X0211699512001809/v0_201502091344/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251412001791"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.pre2012.Jun.11508"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2012;32:683-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5418
      "formatos" => array:3 [
        "EPUB" => 304
        "HTML" => 4498
        "PDF" => 616
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Disseminated histoplasmosis and haemophagocytic syndrome in two kidney transplant patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "683"
          "paginaFinal" => "684"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Histoplasmosis diseminada y s&#237;ndrome hemofagoc&#237;tico en dos pacientes trasplantados renales"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier Espa&#241;a"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "11508_16025_36073_en_t111508.jpg"
              "Alto" => 531
              "Ancho" => 1442
              "Tamanyo" => 279620
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Diagnostic criteria for haemophagocytic syndrome"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jhon F&#46; Nieto-R&#237;os, Arbey Aristizabal-Alzate, Catalina Ocampo, Ana K&#46; Serrano-Gayubo, Lina M&#46; Serna-Higuita, Gustavo Zuluaga-Valencia"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Jhon F&#46;"
              "apellidos" => "Nieto-R&#237;os"
            ]
            1 => array:2 [
              "nombre" => "Arbey"
              "apellidos" => "Aristizabal-Alzate"
            ]
            2 => array:2 [
              "nombre" => "Catalina"
              "apellidos" => "Ocampo"
            ]
            3 => array:2 [
              "nombre" => "Ana K&#46;"
              "apellidos" => "Serrano-Gayubo"
            ]
            4 => array:2 [
              "nombre" => "Lina M&#46;"
              "apellidos" => "Serna-Higuita"
            ]
            5 => array:2 [
              "nombre" => "Gustavo"
              "apellidos" => "Zuluaga-Valencia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699512001794"
        "doi" => "10.3265/Nefrologia.pre2012.Jun.11508"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001794?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001791?idApp=UINPBA000064"
    "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001791/v0_201502091606/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251412001814"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.pre2012.Jun.11528"
    "estado" => "S300"
    "fechaPublicacion" => "2012-09-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2012;32:680-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3755
      "formatos" => array:3 [
        "EPUB" => 303
        "HTML" => 2947
        "PDF" => 505
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "On-Line haemodialfiltration versus high flux haemodialysis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "680"
          "paginaFinal" => "682"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Hemodiafiltraci&#243;n on-line frente a hemodi&#225;lisis de alto flujo"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier Espa&#241;a"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "11528_16025_36080_en_t111528.jpg"
              "Alto" => 517
              "Ancho" => 1443
              "Tamanyo" => 284388
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Patient Data"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Antonio Gomis-Couto, Sandra El&#237;as, Milagros Fern&#225;ndez-Lucas, Gloria Ruiz-Roso, Martha D&#237;az-Dom&#237;nguez, Jos&#233; L&#46; Teruel, Carlos Quereda"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Antonio"
              "apellidos" => "Gomis-Couto"
            ]
            1 => array:2 [
              "nombre" => "Sandra"
              "apellidos" => "El&#237;as"
            ]
            2 => array:2 [
              "nombre" => "Milagros"
              "apellidos" => "Fern&#225;ndez-Lucas"
            ]
            3 => array:2 [
              "nombre" => "Gloria"
              "apellidos" => "Ruiz-Roso"
            ]
            4 => array:2 [
              "nombre" => "Martha"
              "apellidos" => "D&#237;az-Dom&#237;nguez"
            ]
            5 => array:2 [
              "nombre" => "Jos&#233; L&#46;"
              "apellidos" => "Teruel"
            ]
            6 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Quereda"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699512001817"
        "doi" => "10.3265/Nefrologia.pre2012.Jun.11528"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699512001817?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001814?idApp=UINPBA000064"
    "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001814/v0_201502091606/en/main.assets"
  ]
  "en" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Chronic renal failure and peripheral arterial disease"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "682"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Santiago Suria-Gonz&#225;lez, Noem&#237; Esparza-Mart&#237;n, Pablo Braillard-Poccard, Antonio Calder&#237;n-Ortega, M&#46; Dolores Checa-Andr&#233;s"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Santiago"
            "apellidos" => "Suria-Gonz&#225;lez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Noem&#237;"
            "apellidos" => "Esparza-Mart&#237;n"
            "email" => array:1 [
              0 => "noemiesparza&#64;telefonica&#46;net"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Pablo"
            "apellidos" => "Braillard-Poccard"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Antonio"
            "apellidos" => "Calder&#237;n-Ortega"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "affb"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "M&#46; Dolores"
            "apellidos" => "Checa-Andr&#233;s"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria   "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Angiología y Cirugía Vascular, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria   "
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "affb"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Insuficiencia renal cr&#243;nica y enfermedad arterial perif&#233;rica"
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">To the Editor&#58;</span></p><p class="elsevierStylePara">It has been well established that both patients with chronic renal failure &#40;CRF&#41; and those with peripheral arterial disease &#40;PAD&#41; have increased the risk of death due to cardiovascular disease&#46; Red blood cell distribution width &#40;RDW&#41; is a marker for mortality in patients with established cardiovascular disease&#46; It has been demonstrated that for every 1&#37; increase in RDW&#44; the risk of death increases by 14&#37;&#46;<span class="elsevierStyleSup">1</span> Increased levels of N-terminal pro-brain natriuretic peptide &#40;NT-proBNP&#41; are also associated with increased cardiovascular mortality and morbidity rates in the general population&#46;<span class="elsevierStyleSup">2</span> With this in mind&#44; we sought to evaluate RDW percentage and NT-proBNP levels in patients with peripheral arterial disease &#40;PAD&#41; with or without CRF&#46;</p><p class="elsevierStylePara">We performed a cross-sectional observational study involving 40 patients with PAD &#40;all in stage III or IV on the Fontaine scale&#41;&#44; with no signs of heart failure&#46; Of these&#44; 17 had CRF and 23 did not&#44; 33 were male and 7 were female&#44; and the mean age was 68&#46;03&#177;11&#46;10&#46; The patients were evaluated upon admission to the vascular surgery department&#46; After signing an informed consent form &#40;study approved by the ethics committee&#41;&#44; we compiled clinical&#44; pharmacological&#44; and laboratory values for each patient&#46; NT-proBNP was measured using a solid phase radial partition immunoassay &#40;Acute Care<span class="elsevierStyleSup">&#174; </span>for Stratus<span class="elsevierStyleSup">&#174;</span> CS&#44; Siemens&#41;&#46; Statistical analyses were performed using SPSS statistical software&#44; version 15&#46;0&#46;</p><p class="elsevierStylePara">The 40 patients with PAD had the following mean values&#58; body mass index&#58; 26&#46;32&#177;4&#46;71kg&#47;m<span class="elsevierStyleSup">2</span>&#59; systolic blood pressure&#58; 133&#46;82&#177;19&#46;10mm Hg&#59; diastolic blood pressure&#58; 75&#46;78&#177;11&#46;30mm Hg&#59; and heart rate&#58; 78&#46;18&#177;10&#46;95bpm&#46; Fifty percent of the patients were active smokers&#44; 82&#46;5&#37; were ex-smokers&#44; 27 were diabetics&#44; and 27 had hypertension&#46; Upon dividing the patients based on the presence or absence of CRF&#44; we found that patients with an MDRD4 score &#60;60ml&#47;min &#40;mean&#58; 41&#46;57&#177;11&#46;38ml&#47;min&#41; were older &#40;73&#46;75&#177;10&#46;84 years vs 63&#46;87&#177;9&#46;51 years&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;007&#41;&#44; more prone to hypertension &#40;88&#46;23&#37; vs 57&#46;14&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;02&#41;&#44; and received treatment with beta blockers &#40;52&#46;94&#37; vs 21&#46;74&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;041&#41; and angiotensin II receptor blockers &#40;ARBs&#41; &#40;35&#46;29&#37; vs 21&#46;74&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;038&#41; at a greater rate than patients with an MDRD4&#62;60ml&#47;min &#40;81&#46;54&#177;20&#46;90ml&#47;min&#41;&#44; with no other differences found in terms of drugs administered&#46; There were also no differences in terms of sex distribution&#44; frequency of diabetes&#44; or tobacco use between these two sub-groups&#46; As regards the objectives of our study&#44; we found that patients with CRF had higher levels of NT-proBNP &#40;2561&#46;18&#177;2526&#46;95mg&#47;dl vs&#46; 805&#46;48&#177;1036&#46;02mg&#47;dl&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;01&#41; and a higher RDW percentage &#40;15&#46;54&#177;2&#46;27&#37; vs 14&#46;74&#177;2&#46;11&#37;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;044&#41; than patients with PAD and without CRF&#46; The percentage of RDW was positively correlated with NT-proBNP levels &#40;r&#61;0&#46;56&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;001&#41;&#46;</p><p class="elsevierStylePara">Based on these results&#44; and despite the small number of patients examined&#44; we could affirm that patients with PAD and CRF have higher levels of biological markers of morbidity&#47;mortality than those with PAD and without CRF&#44; which would imply a greater associated cardiovascular risk and perioperative risk<span class="elsevierStyleSup">3</span> than in patients without CRF&#46;<span class="elsevierStyleSup">3</span> The finding of a positive correlation between RDW and NT-proBNP in these patients could suggest a possible association with cardiorenal syndrome&#46; Further studies with more patients could affirm whether patients with PAD treated with beta blockers or ARBs have a higher rate of CRF&#46;</p><p class="elsevierStylePara">&#160;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">Conflicts of interest</span></p><p class="elsevierStylePara">&#160;</p><p class="elsevierStylePara">The authors have no conflicts of interest to declare&#46;</p>"
    "pdfFichero" => "P1-E543-S3702-A11569-EN.pdf"
    "tienePdf" => true
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Patel KV,\u{A0}Ferrucci L,\u{A0}Ershler WB,\u{A0}Longo DL,\u{A0}Guralnik JM.\u{A0}Red Cell Distribution Width and the Risk of Death in Middle-aged and Older Adults. Arch Intern Med 2009;169(5):515-23. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19273783" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Daniels LB. Natriuretic Peptides and Assessment of Cardiovascular Disease Risk in Asymptomatic Persons. Curr Cardiovasc Risk Rep 2010;4(2):120-7."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Wazni OM, Martin DO, Marrouche NF, Latif AA, Ziada K, Shaaraoui M, et al. Plasma B-type natriuretic peptide levels predict postoperative atrial fibrillation in patients undergoing cardiac surgery. Circulation 2004;110:124-7. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15210589" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003200000005/v0_201502091606/X2013251412001806/v0_201502091606/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35438"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor - Brief papers about basic research or clinical experiences"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003200000005/v0_201502091606/X2013251412001806/v0_201502091606/en/P1-E543-S3702-A11569-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001806?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 5 5 10
2024 October 35 44 79
2024 September 41 26 67
2024 August 56 56 112
2024 July 35 29 64
2024 June 51 38 89
2024 May 49 30 79
2024 April 41 29 70
2024 March 38 20 58
2024 February 34 35 69
2024 January 27 35 62
2023 December 22 24 46
2023 November 25 34 59
2023 October 57 25 82
2023 September 65 36 101
2023 August 59 13 72
2023 July 42 22 64
2023 June 55 22 77
2023 May 71 31 102
2023 April 50 19 69
2023 March 53 15 68
2023 February 53 26 79
2023 January 31 18 49
2022 December 32 32 64
2022 November 41 38 79
2022 October 37 40 77
2022 September 48 19 67
2022 August 39 47 86
2022 July 26 39 65
2022 June 35 41 76
2022 May 19 33 52
2022 April 35 42 77
2022 March 33 34 67
2022 February 27 46 73
2022 January 28 22 50
2021 December 24 45 69
2021 November 29 34 63
2021 October 29 33 62
2021 September 27 40 67
2021 August 24 34 58
2021 July 33 36 69
2021 June 17 16 33
2021 May 28 28 56
2021 April 37 47 84
2021 March 32 36 68
2021 February 26 13 39
2021 January 19 21 40
2020 December 17 9 26
2020 November 27 12 39
2020 October 20 17 37
2020 September 16 11 27
2020 August 24 9 33
2020 July 33 7 40
2020 June 19 12 31
2020 May 21 11 32
2020 April 23 14 37
2020 March 20 13 33
2020 February 30 16 46
2020 January 26 19 45
2019 December 33 18 51
2019 November 19 21 40
2019 October 17 8 25
2019 September 23 14 37
2019 August 12 10 22
2019 July 16 18 34
2019 June 18 14 32
2019 May 16 17 33
2019 April 33 43 76
2019 March 30 27 57
2019 February 14 20 34
2019 January 26 19 45
2018 December 63 38 101
2018 November 81 11 92
2018 October 60 13 73
2018 September 53 14 67
2018 August 43 15 58
2018 July 54 11 65
2018 June 47 11 58
2018 May 60 17 77
2018 April 57 10 67
2018 March 63 11 74
2018 February 58 7 65
2018 January 52 8 60
2017 December 48 13 61
2017 November 33 6 39
2017 October 26 7 33
2017 September 37 14 51
2017 August 32 12 44
2017 July 26 12 38
2017 June 26 13 39
2017 May 30 13 43
2017 April 39 7 46
2017 March 17 3 20
2017 February 19 9 28
2017 January 19 5 24
2016 December 38 4 42
2016 November 39 8 47
2016 October 50 8 58
2016 September 69 5 74
2016 August 125 3 128
2016 July 118 6 124
2016 June 101 0 101
2016 May 97 0 97
2016 April 69 0 69
2016 March 68 0 68
2016 February 72 0 72
2016 January 65 0 65
2015 December 103 0 103
2015 November 75 0 75
2015 October 71 0 71
2015 September 64 0 64
2015 August 76 0 76
2015 July 67 0 67
2015 June 39 0 39
2015 May 41 0 41
2015 April 5 0 5
Show all

Follow this link to access the full text of the article

Idiomas
Nefrología (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?