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"apellidos" => "Méndez-López" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "affb" ] ] ] 7 => array:3 [ "nombre" => "Luis" "apellidos" => "Budar-Fernandez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "affe" ] ] ] 8 => array:3 [ "nombre" => "Luis" "apellidos" => "Budar-Fernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "affb" ] ] ] 9 => array:3 [ "nombre" => "Felipe" "apellidos" => "González-Velázquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "afff" ] ] ] ] "afiliaciones" => array:6 [ 0 => array:3 [ "entidad" => "Servicio de Trasplantes, IMSS UMAE 189 ARC, Hospital Regional de Alta Especialidad de Veracruz, Veracruz, México, " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] 1 => array:3 [ "entidad" => "Servicio de Trasplantes, IMSS UMAE 189 ARC, Veracruz, México, " "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "affb" ] 2 => array:3 [ "entidad" => "Servicio de Trasplantes, Hospital Regional de Alta Especialidad de Veracruz, Veracruz, Mexico, " "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "affc" ] 3 => array:3 [ "entidad" => "Servicio de Trasplantes, Hospital Regional de Alta Especialidad de Veracruz, Veracruz, México, " "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "affd" ] 4 => array:3 [ "entidad" => "Servicio de Trasplantes, IMSS UMAE 189 ARC, Veracruz, Mexico, " "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "affe" ] 5 => array:3 [ "entidad" => "Servicio de Investigación, IMSS UMAE 189 ARC, Veracruz, México, " "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "afff" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Factores asociados con el cambio temprano de catéter de diálisis peritoneal en Veracruz, México" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig1" "etiqueta" => "Tab. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11295_16025_29775_en_t111295.jpg" "Alto" => 1468 "Ancho" => 2178 "Tamanyo" => 896479 ] ] "descripcion" => array:1 [ "en" => "Comparison of patients with peritoneal dialysis catheter dysfunction and those without" ] ] ] "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">INTRODUCTION</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">Continuous ambulatory peritoneal dialysis (PD) has become an established option for treating patients with end-stage renal disease. This therapy requires the insertion of a permanent PD catheter. An estimated 25% of the world population on PD lives in Latin America. In particular, Mexico is the country with the highest use of this technique in the world.<span class="elsevierStyleSup">1</span></p><p class="elsevierStylePara">PD catheters are inserted using various techniques. Open surgical approaches can involve midline,<span class="elsevierStyleSup">2-4</span> paramedian infra-umbilical laparotomy<span class="elsevierStyleSup">5,6</span> or multiple laparoscopic approaches.<span class="elsevierStyleSup">7-10</span> Although laparoscopy has become the surgical method of choice for placing PD catheters, open surgery techniques remain as an important option when laparoscopic resources are limited, whether due to the <span class="elsevierStyleBold">lack of laparoscopic equipment in different hospitals</span> due to costs, or due to operator limitations.</p><p class="elsevierStylePara">Complications associated with PD contribute significantly to morbidity and mortality rates, interruption of treatment, and decreased efficacy of dialysis, in addition to causing the need for conversion to haemodialysis, hospitalisation, and subsequent surgeries. Early and late complications such as surgical wound infection, peritonitis, and catheter dysfunction due to migration, obstruction, bleeding, granuloma, or post-incisional hernia limit the long-term survival of the PD catheter in 35%-51% of cases after 24 months.<span class="elsevierStyleSup">11</span> An 80% catheter survival rate after one year has been recommended as a target for PD centres,<span class="elsevierStyleSup">5,8,12</span> and can be reached using the most economical resources available and techniques appropriate for each PD unit. With the goal of minimising morbidity rates associated with this therapy,<span class="elsevierStyleSup">13</span> it is important to take into account patient characteristics that increase the risk of developing complications, making an examination of pre-existing conditions necessary.</p><p class="elsevierStylePara">Several studies associated complications with different factors including age, gender, diabetes, sepsis, prolonged duration of surgery, and previous abdominal surgery<span class="elsevierStyleSup">5,14-17</span>. Several authors observed that an omentectomy and/or omental wrapping prevents catheter dysfunction, while other studies showed no correlation between previous omentectomy or abdominal surgery and postoperative complications.<span class="elsevierStyleSup">3,7,18-20</span></p><p class="elsevierStylePara">The aim of this article was to present the results from our experience in the insertion of PD catheters and to determine which factors involve a higher risk for early catheter dysfunction and affect 1-year survival rates.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">METHODS</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Patients</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">We performed a retrospective review of clinical histories from patients with end-stage renal disease that underwent open surgery for catheter placement in preparation for the start of PD.</p><p class="elsevierStylePara">All procedures were performed by a single surgeon between January 2004 and January 2010. Demographical data, patient characteristics, surgical records, and catheter complications during the first year requiring catheter replacement were collected and analysed. We received approval from the Institutional Review Board and the Bioethics Committee for data collection and analysis, respectively.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Surgical procedure</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">Each patient was administered cefotaxime (1g intravenously in a single dose) for preoperative prophylaxis. All catheters used were standard Dacron double-cuff straight Tenckhoff catheters. Anaesthetic technique was determined on a case-by-case basis by the attending anaesthesiologist. Each catheter was inserted by mini-laparotomy through a vertical midline infra-umbilical incision of approximately 3cm-4cm. The peritoneum was exposed using an open surgical technique, and the catheter was placed directly in the pelvic cavity. After placement, the internal cuff was joined to the peritoneum with a 2/0 chromic suture and permeability was verified. The linea alba was closed using size 1 polyglycolic acid suture. The catheter was removed from the peritoneal cavity through the wound, and the end of the catheter was tunnelled subcutaneously, passing through the skin in a small para-umbilical incision with the external Dacron cuff in the subcutaneous tissue. The subcutaneous tissue and skin were closed using standard procedure. Dialysate solution was immediately infused into the peritoneal cavity while in the operating room in order to ensure there was no leakage of dialysate fluid. The decision to perform an omentectomy was left to the surgeon’s judgement, depending on whether the omentum was accessible through the incision, the size of the omentum, and whether it could reach the catheter and obstruct it. Recently (since 2010), omentopexy has been performed using the same criteria as omentectomy. Omentopexy involves anchoring the omentum to the abdominal wall above the infra-umbilical incision with interrupted absorbable sutures (2/0 chromic) from the omentum to the peritoneum wall and bilaterally around the navel. The majority of patients started on PD within 24 hours of catheter placement, <span class="elsevierStyleBold">using continuous ambulatory PD with a predetermined infusion volume of 2000cc in all cases</span>. Catheter replacement was requested by the nephrology department, once salvage treatment was determined to have failed.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Statistical analysis</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">We performed a simple descriptive analysis of the data. Categorical variables were described using proportions, and continuous variables with a normal distribution were described using mean (standard deviation). We used Student’s t-tests and Mann-Whitney U-tests to evaluate differences for catheter dysfunction between continuous variables with normal and non-normal distribution, respectively. Categorical variables were analysed using chi-square tests or Fisher’s exact tests to identify variables associated with catheter dysfunction. We determined odds ratios (OR) and created a logistic regression model in order to determine the risk factors in the univariate analysis. We considered a <span class="elsevierStyleItalic">P</span>-value <0.05 to be statistically significant, and used SPSS™ software, version 17.0, for all statistical analyses (SPSS, Chicago, IL, USA).</p><p class="elsevierStylePara"><span class="elsevierStyleBold"> </span></p><p class="elsevierStylePara"><span class="elsevierStyleBold">RESULTS</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Patient and surgical registry characteristics</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">During the study period, a total of 235 patients were placed catheters (118 women and 117 men). Mean patient age was 51.4±17.5 years (range: 13-86 years), mean body mass index (BMI) was 26.3±4.2kg/m<span class="elsevierStyleSup">2</span> (range: 14.4-40), and mean body surface area<span class="elsevierStyleSup">21</span> (BSA; Mosteller) was 1.7±0.1m<span class="elsevierStyleSup">2</span> (range: 1.06-2.1). Some 43% of patients (n=101) had diabetic nephropathy, and only 3% (n=7) had autosomal dominant polycystic kidney disease.</p><p class="elsevierStylePara">Forty-six of the 235 patients (19.6%) had a history of previous abdominal surgery. Of these, only 26 had previously undergone one surgical procedure before, 12 patients had undergone two previous surgical procedures, 4 had undergone three previous surgical procedures, and 4 patients had undergone more than 3 previous surgical procedures. Regional anaesthesia was used in 95.8% of cases (n=225) during catheter placement; and general and local anaesthesia protocols were used evenly (2.1%, n=5 each). Mean duration of surgery was 43.7±14 minutes (range: 15-120). An omentectomy was performed in 37.9% of catheter placements (n=89), and an omentopexy was performed in 10 patients (4.3%). <span class="elsevierStyleBold">Dialysis was started within 24 hours of catheter placement in 97% of patients (n=230)</span>.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Peritoneal dialysis catheter complications and results</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">Catheter dysfunction that eventually required catheter replacement occurred in 47 patients (20%), and 80% of catheters were incident-free after one year.</p><p class="elsevierStylePara">Catheter dysfunction appeared after a mean 6.8±22.6 days (range: 0-120). The most common causes of catheter dysfunction were migration (4.3%, n=10) and peritonitis (4.3%, n=10), followed by obstruction of the catheter by omental wrapping in 9 patients (3.7%). Eight patients (3.4%) suffered surgical wound infection, and all of them required catheter replacement at some point. Other causes for changing the catheter included bleeding (haemoperitoneum) (2.1%, n=5) and fibrin clots in the catheter (2.1%, n=5). <span class="elsevierStyleBold">The 8 patients with surgical wound infections (3.4%) also had dialysate fluid leaks. Four patients (1.7%) had only one dialysate fluid leak and did not require PD catheter replacement</span>. Another complication that did not require catheter replacement was granuloma in the exit site with subcutaneous tunnel infection in 1.7% of patients (n=4). Ten patients developed post-incisional hernias <span class="elsevierStyleBold">during the first year after catheter placement</span>.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Factors associated with catheter dysfunction</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">We compared patients with and without catheter dysfunction, searching for factors associated with this phenomenon (Table 1). Patients with dysfunction were younger, with lower BMI and BSA than those without dysfunction (<span class="elsevierStyleItalic">P</span><.05). There were no differences between groups with and without diabetes and autosomal <span class="elsevierStyleBold">dominant</span> polycystic kidney disease. We did not find any correlation between previous abdominal surgery and catheter dysfunction, or the duration of the surgical procedure when using a 45-minute cut-off point. Patients that underwent an omentectomy had a lower incidence of catheter dysfunction (11.2%) than patients that did not undergo an omentectomy (25.3%) (<span class="elsevierStyleItalic">P</span><.009). We did not observe a similar association for omentopexy. Patients that developed a post-incisional hernia developed catheter dysfunction in half of all cases (<span class="elsevierStyleItalic">P</span><.03), and all patients with surgical wound infection required catheter replacement (<span class="elsevierStyleItalic">P</span><.0001). The logistic regression analysis showed that having undergone an omentectomy was a statistically significant protective factor against catheter dysfunction (<span class="elsevierStyleItalic">P</span><.05). No other variables that were significant in the univariate analysis for catheter dysfunction had a significant positive or negative impact on risk factors in the multivariate analysis (Table 2).</p><p class="elsevierStylePara"><span class="elsevierStyleBold"> </span></p><p class="elsevierStylePara"><span class="elsevierStyleBold">DISCUSSION</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">Our study showed a considerable level of effectiveness and safety in PD catheter placement using an open surgical approach with an infra-umbilical midline incision. In addition, certain patient variables, such as age, BMI, BSA, and surgical aspects, such as wound infection and post-incisional hernia, were associated with <span class="elsevierStyleBold">early</span> catheter dysfunction and catheter <span class="elsevierStyleBold">replacement</span>, <span class="elsevierStyleBold">contrasting with the protective effect of an omentectomy, which reduced the probability of catheter dysfunction</span>.</p><p class="elsevierStylePara">We observed a wide range of complications that affected the incidence of catheter replacement. The incidence of catheter migration (4.3%) was lower than that of 7.6% reported by Liu et al,<span class="elsevierStyleSup">4</span> and those high rates (22%-24%) reported in other studies.<span class="elsevierStyleSup">5,8</span> In a similar manner, omentum or fibrin obstruction occurred at a combined incidence of 5.8%, lower or similar to rates reported in other studies.<span class="elsevierStyleSup">4,5</span></p><p class="elsevierStylePara">As regards infectious complications, our rate of surgical wound infection was lower than in other studies, and few patients in our study had peritonitis, as compared to an unusual rate of 30% reported in other studies.<span class="elsevierStyleSup">3,5</span> However, we must be cautious in interpreting our results, taking into account that the majority of our complications resulted in catheter replacement, except for 4 patients with dialysate fluid leaks and those patients with complications at the catheter exit site. This may reveal suboptimal salvage manoeuvres, such as anti-infection treatment and catheter recovery using fluoroscopic guidance.</p><p class="elsevierStylePara">One of the intrinsic properties of the omentum is that, when it comes into contact with a foreign body, it attempts to surround and isolate it. Omental wrapping was a very common cause of catheter dysfunction in our study (3.7%). Some authors have suggested performing an omentectomy during catheter placement to avoid wrapping and the need for secondary interventions,<span class="elsevierStyleSup">19</span> since 27% of patients that do not undergo an omentectomy develop catheter obstruction. We also observed a significant difference in catheter dysfunction and replacement when an omentectomy was performed. In our study, omentectomy had a protective effect against catheter dysfunction and replacement in both univariate and multivariate analyses, <span class="elsevierStyleBold">probably due to the reduced rate of obstruction from omental wrapping</span>.</p><p class="elsevierStylePara">The majority of studies assessing PD catheter placement place special emphasis on a previous history of abdominal surgery as a potential risk for PD complications. Tiong et al<span class="elsevierStyleSup">5</span> analysed several factors related to catheter dysfunction and found that patients with a background of diabetes, glomerulonephritis, or previous abdominal surgery had a higher probability (OR: 3.24; 6.52; 3.42, respectively) of early complications (within 30 days after catheter placement) in a population with a prevalence rate of 43.8% for previous surgery. A longer duration of the surgical procedure was also associated with early complications. Another study examining hernias as a potential complication of PD catheter placement<span class="elsevierStyleSup">17</span> found that patients with polycystic kidney disease had a 2.5 times higher risk of complications, and that female sex was a protective factor against the occurrence of hernias. Although we observed several factors, including age, BMI, BSA, wound infection, and post-incisional hernia that were associated with catheter dysfunction in the univariate analysis, none were associated with a higher risk of catheter dysfunction and replacement in the logistic regression analysis. Crabtree et al<span class="elsevierStyleSup">22</span> observed that abdominal scarring and previous history of peritonitis did not predict the severity of adherences and should not be used for deciding whether or not to use PD. We did not observe any relationship with other aspects of surgery, such as previous abdominal surgery or pre-existing medical conditions (for example, diabetes mellitus, polycystic kidney disease) that might affect selection criteria for entering our PD programme in the future. Currently, we do not assess patients based on previous abdominal surgery in order to use PD as a renal replacement therapy, despite the low prevalence of previous abdominal surgery (19.6%) as compared to other studies.<span class="elsevierStyleSup">5,22</span> We should point out that in several of the previously mentioned studies the PD catheters were placed by several different surgical teams, whereas in our study only one surgical team performed all procedures, <span class="elsevierStyleBold">which partially standardises the results, ensuring that the same criteria were used for performing an omentectomy or omentopexy and that the procedure was systematic</span>.</p><p class="elsevierStylePara">Our study had several limitations, primarily those related to the retrospective design of the study, such as a biased sample selection, no control group, and difficulties in measuring and recording data for the different variables assessed. Another issue in our results lies in the open approach used for catheter placement: laparoscopic techniques are used more and more frequently<span class="elsevierStyleSup">7,9,10,19,20,22</span>; however, several centres, mainly from Asia, still use open techniques with good results.<span class="elsevierStyleSup">2-6,17 </span>In particular, we used an open approach for several reasons: firstly, we have limited use of laparoscopic techniques due to equipment and financial limitations, and secondly, both the open technique using a midline incision and the subjective criteria used for deciding to perform an omentectomy are easy to learn and reproduce by the residents at our hospital. In addition, our results are similar or better than the results from Asian studies involving open techniques in terms of mechanical complications<span class="elsevierStyleSup">4,5,8</span> and even better than results from laparoscopic techniques,<span class="elsevierStyleSup">7,9,10</span> so we have continued to use an open surgical approach.</p><p class="elsevierStylePara">In conclusion, PD catheter placement using an open surgical approach with an infra-umbilical midline incision offers good results with few surgical complications after one year. In our study, we did not find significant risk factors for <span class="elsevierStyleBold">early</span> catheter replacement. Omentectomy had a protective effect against catheter dysfunction and replacement. A prospective, randomised study evaluating omentectomy and PD catheter placement would confirm our conclusions.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Conflicts of interest</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">The authors affirm that they have no conflicts of interest related to the content of this article.</p><p class="elsevierStylePara"><a href="grande/11295_16025_29775_en_t111295.jpg" class="elsevierStyleCrossRefs"><img src="11295_16025_29775_en_t111295.jpg" alt="Comparison of patients with peritoneal dialysis catheter dysfunction and those without"></img></a></p><p class="elsevierStylePara">Table 1. Comparison of patients with peritoneal dialysis catheter dysfunction and those without</p><p class="elsevierStylePara"><a href="grande/11295_16025_29776_en_t211295.jpg" class="elsevierStyleCrossRefs"><img src="11295_16025_29776_en_t211295.jpg" alt="Predictive factors for peritoneal dialysis catheter dysfunction"></img></a></p><p class="elsevierStylePara">Table 2. Predictive factors for peritoneal dialysis catheter dysfunction</p>" "pdfFichero" => "P1-E536-S3491-A11295-EN.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:5 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438377" "palabras" => array:1 [ 0 => "Resultados" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438379" "palabras" => array:1 [ 0 => "Complicaciones" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438381" "palabras" => array:1 [ 0 => "Factores de riesgo" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438383" "palabras" => array:1 [ 0 => "Cirugía" ] ] 4 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438385" "palabras" => array:1 [ 0 => "Diálisis peritoneal" ] ] ] "en" => array:5 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438378" "palabras" => array:1 [ 0 => "Outcome" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438380" "palabras" => array:1 [ 0 => "Complications" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438382" "palabras" => array:1 [ 0 => "Risk factors" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438384" "palabras" => array:1 [ 0 => "Surgery" ] ] 4 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438386" "palabras" => array:1 [ 0 => "Peritoneal dialysis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Antecedentes</span>: Las complicaciones asociadas con el catéter en diálisis peritoneal causan disminución en su eficacia e interrupción de ésta, conversión a hemodiálisis, hospitalizaciones y necesidad de cirugía para cambiar el catéter. <span class="elsevierStyleBold">Objetivos:</span> Determinar factores de riesgo para la disfunción <span class="elsevierStyleBold">temprana</span> del catéter que hace necesario su cambio. <span class="elsevierStyleBold">Métodos:</span> Se incluyeron 235 catéteres colocados con técnica quirúrgica abierta en línea media infraumbilical. Dentro de los posibles factores de riesgo se incluyó: edad, género, índice de masa corporal, área de superficie corporal, diabetes, enfermedad poliquística renal, cirugía previa, tiempo quirúrgico, omentectomía, omentopexia, infección de la herida y hernia posincisional. <span class="elsevierStyleBold">Resultados:</span> El cambio del catéter por disfuncionalidad ocurrió en 47 pacientes (20%) durante el primer año. La complicación más frecuente fue: migración del catéter y peritonitis (4,3% en ambos casos), además de obstrucción por el omento (3,7%). En el análisis univariado, los pacientes que presentaron disfunción del catéter/cambio eran jóvenes con índice de masa corporal y área de superficie corporal bajos (p < 0,05). La infección de la herida y la hernia posincisional estaban asociados significativamente con el cambio de catéter. La omentectomía fue asociada a baja incidencia de disfunción de catéter/cambio en el análisis univariado y regresión logística (razón de momios: 0,275, intervalo de confianza: 95%, 0,101-0,751, p < 0,012). <span class="elsevierStyleBold">Conclusiones</span>: Nuestra técnica de inserción de catéter ofrece bajas tasas de complicaciones y buenos resultados el primer año posquirúrgico. Además de la omentectomía, en nuestro estudio no se encontró un factor de riesgo para cambio de catéter en nuestra población. La omentectomía tuvo un efecto protector en términos de cambio de catéter.</p>" ] "en" => array:1 [ "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Introduction: </span>Catheter-related complications in patients on peritoneal dialysis lead to decreased effectiveness and discontinuation of the technique, conversion to haemodialysis, hospitalisation, and surgical interventions to replace the catheter. <span class="elsevierStyleBold">Objectives:</span> Determine risk factors for early catheter dysfunction that result in the need for replacement. <span class="elsevierStyleBold">Methods:</span> We analysed 235 catheters placed by open surgery using an infra-umbilical midline incision. Possible risk factors included the following: age, sex, body mass index, body surface area, diabetes, polycystic kidney disease, previous surgery, time of surgical procedure, omentectomy, omentopexy, wound infection and postoperative incisional hernia. <span class="elsevierStyleBold">Results:</span> During the first year, 47 patients (20%) required a catheter replacement due to poor function. The most common complications were catheter migration and peritonitis (4.3% in both cases), followed by obstruction from omental wrapping (3.7%). Univariate analysis showed that patients with catheter dysfunction or requiring catheter replacement were younger, with a lower body mass index and body surface area (<span class="elsevierStyleItalic">P</span><.05). There was a significant association of wound infection and post-operative incisional hernia with catheter replacement. Omentectomy was associated with a low incidence rate of catheter dysfunction/replacement in the univariate and logistical regression analyses (odds ratio: 0.275; 95% confidence interval: 0.101-0.751; <span class="elsevierStyleItalic">P</span><.012). <span class="elsevierStyleBold">Conclusions:</span> Our catheter placement technique offers a low complication rate and good results in the first year after surgery. Except for omentectomy, we did not discover any risk factors for catheter replacement in our study population. Omentectomy had a protective effect in terms of catheter replacement.</p>" ] ] "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig1" "etiqueta" => "Tab. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11295_16025_29775_en_t111295.jpg" "Alto" => 1468 "Ancho" => 2178 "Tamanyo" => 896479 ] ] "descripcion" => array:1 [ "en" => "Comparison of patients with peritoneal dialysis catheter dysfunction and those without" ] ] 1 => array:8 [ "identificador" => "fig2" "etiqueta" => "Tab. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11295_16025_29776_en_t211295.jpg" "Alto" => 459 "Ancho" => 2186 "Tamanyo" => 318824 ] ] "descripcion" => array:1 [ "en" => "Predictive factors for peritoneal dialysis catheter dysfunction" ] ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000003200000003/v0_201502091613/X2013251412001258/v0_201502091613/en/main.assets" "Apartado" => array:4 [ "identificador" => "35441" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originals" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003200000003/v0_201502091613/X2013251412001258/v0_201502091613/en/P1-E536-S3491-A11295-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251412001258?idApp=UINPBA000064" ]
Year/Month | Html | Total | |
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2024 November | 9 | 10 | 19 |
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2024 August | 73 | 54 | 127 |
2024 July | 49 | 46 | 95 |
2024 June | 78 | 48 | 126 |
2024 May | 79 | 48 | 127 |
2024 April | 56 | 39 | 95 |
2024 March | 63 | 29 | 92 |
2024 February | 59 | 46 | 105 |
2024 January | 54 | 26 | 80 |
2023 December | 31 | 25 | 56 |
2023 November | 49 | 41 | 90 |
2023 October | 49 | 36 | 85 |
2023 September | 59 | 32 | 91 |
2023 August | 75 | 25 | 100 |
2023 July | 92 | 40 | 132 |
2023 June | 51 | 42 | 93 |
2023 May | 82 | 45 | 127 |
2023 April | 68 | 21 | 89 |
2023 March | 57 | 22 | 79 |
2023 February | 51 | 14 | 65 |
2023 January | 51 | 38 | 89 |
2022 December | 72 | 29 | 101 |
2022 November | 52 | 40 | 92 |
2022 October | 70 | 36 | 106 |
2022 September | 57 | 44 | 101 |
2022 August | 44 | 52 | 96 |
2022 July | 39 | 38 | 77 |
2022 June | 59 | 44 | 103 |
2022 May | 46 | 31 | 77 |
2022 April | 60 | 61 | 121 |
2022 March | 62 | 57 | 119 |
2022 February | 72 | 38 | 110 |
2022 January | 71 | 44 | 115 |
2021 December | 50 | 42 | 92 |
2021 November | 50 | 48 | 98 |
2021 October | 48 | 42 | 90 |
2021 September | 54 | 32 | 86 |
2021 August | 38 | 37 | 75 |
2021 July | 58 | 29 | 87 |
2021 June | 52 | 23 | 75 |
2021 May | 75 | 54 | 129 |
2021 April | 133 | 69 | 202 |
2021 March | 119 | 41 | 160 |
2021 February | 77 | 24 | 101 |
2021 January | 53 | 21 | 74 |
2020 December | 43 | 22 | 65 |
2020 November | 46 | 13 | 59 |
2020 October | 25 | 19 | 44 |
2020 September | 49 | 7 | 56 |
2020 August | 48 | 12 | 60 |
2020 July | 42 | 6 | 48 |
2020 June | 58 | 12 | 70 |
2020 May | 61 | 13 | 74 |
2020 April | 57 | 22 | 79 |
2020 March | 46 | 20 | 66 |
2020 February | 47 | 22 | 69 |
2020 January | 73 | 15 | 88 |
2019 December | 72 | 44 | 116 |
2019 November | 57 | 26 | 83 |
2019 October | 71 | 21 | 92 |
2019 September | 65 | 21 | 86 |
2019 August | 37 | 16 | 53 |
2019 July | 68 | 27 | 95 |
2019 June | 61 | 23 | 84 |
2019 May | 68 | 23 | 91 |
2019 April | 104 | 41 | 145 |
2019 March | 50 | 27 | 77 |
2019 February | 59 | 24 | 83 |
2019 January | 53 | 24 | 77 |
2018 December | 159 | 42 | 201 |
2018 November | 144 | 24 | 168 |
2018 October | 143 | 16 | 159 |
2018 September | 111 | 12 | 123 |
2018 August | 95 | 27 | 122 |
2018 July | 87 | 17 | 104 |
2018 June | 89 | 19 | 108 |
2018 May | 116 | 17 | 133 |
2018 April | 103 | 11 | 114 |
2018 March | 121 | 8 | 129 |
2018 February | 135 | 15 | 150 |
2018 January | 94 | 9 | 103 |
2017 December | 146 | 11 | 157 |
2017 November | 97 | 17 | 114 |
2017 October | 54 | 12 | 66 |
2017 September | 68 | 15 | 83 |
2017 August | 66 | 16 | 82 |
2017 July | 75 | 20 | 95 |
2017 June | 78 | 13 | 91 |
2017 May | 91 | 10 | 101 |
2017 April | 51 | 15 | 66 |
2017 March | 59 | 18 | 77 |
2017 February | 124 | 10 | 134 |
2017 January | 48 | 9 | 57 |
2016 December | 81 | 8 | 89 |
2016 November | 73 | 15 | 88 |
2016 October | 167 | 12 | 179 |
2016 September | 233 | 8 | 241 |
2016 August | 290 | 8 | 298 |
2016 July | 199 | 21 | 220 |
2016 June | 129 | 0 | 129 |
2016 May | 168 | 0 | 168 |
2016 April | 141 | 0 | 141 |
2016 March | 120 | 0 | 120 |
2016 February | 154 | 0 | 154 |
2016 January | 138 | 0 | 138 |
2015 December | 148 | 0 | 148 |
2015 November | 119 | 0 | 119 |
2015 October | 114 | 0 | 114 |
2015 September | 102 | 0 | 102 |
2015 August | 89 | 0 | 89 |
2015 July | 86 | 0 | 86 |
2015 June | 53 | 0 | 53 |
2015 May | 59 | 0 | 59 |
2015 April | 7 | 0 | 7 |