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Santos Nores, E. Novoa Fernández, O. Conde Rivera, E. Iglesias Lamas, C. Pérez Melón" "autores" => array:5 [ 0 => array:4 [ "Iniciales" => "J." "apellidos" => "Santos Nores" "email" => array:1 [ 0 => "juansn_5@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 1 => array:3 [ "Iniciales" => "E." "apellidos" => "Novoa Fernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 2 => array:3 [ "Iniciales" => "O." "apellidos" => "Conde Rivera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 3 => array:3 [ "Iniciales" => "E." "apellidos" => "Iglesias Lamas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 4 => array:3 [ "Iniciales" => "C." "apellidos" => "Pérez Melón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Nefrología, Complexo Hospitalario de Ourense, " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Revisión de los protocolos y patrones propios de infección: una herramienta útil en el tratamiento de las peritonitis" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig1" "etiqueta" => "Tab. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11003_108_25061_en_11003_t1.jpg" "Alto" => 472 "Ancho" => 600 "Tamanyo" => 185858 ] ] "descripcion" => array:1 [ "en" => "Micro-organisms responsible for cases of peritonitis in 2009 and 2010" ] ] ] "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">To the Editor, </span></p><p class="elsevierStylePara">Peritonitis continues to be one of the primary complications associated with peritoneal dialysis (PD), as well as being an important cause of morbidity, mortality, and technique failure.<span class="elsevierStyleSup">1</span></p><p class="elsevierStylePara">Cases of peritonitis produced by gram-negative bacteria are frequently more severe than others, implying a worse clinical prognosis and time on PD.<span class="elsevierStyleSup">2</span></p><p class="elsevierStylePara">This is fundamentally due to a number of intrinsic properties of gram-negative bacteria. Firstly, we should mention the high virulence inherent to gram-negative bacteria. Infections from <span class="elsevierStyleItalic">Pseudomonas</span> are the most common cause of severe cases of peritonitis, with high percentages of catheter loss and technique failure,<span class="elsevierStyleSup">3</span> and the same can be said for those caused by <span class="elsevierStyleItalic">Escherichia coli </span>and enterobacteria, with complete recovery of less than 60% of cases in some studies.<span class="elsevierStyleSup">4</span></p><p class="elsevierStylePara">A second important factor is the origin of the infection, since peritonitis caused by gram-negative bacteria is associated with contamination, infections of the outflow site, and intra-abdominal contamination. Finally, we should also point out the ability of gram-negative bacteria to protect themselves from antibiotic treatment thanks to a biofilm that forms in the catheter.<span class="elsevierStyleSup">1</span></p><p class="elsevierStylePara">In order to improve the results of treating these infections, a PD programme must have protocols for preventive care and the treatment of infectious complications, both peritonitis and infections related to the orifices and catheter. The patterns of infection at each centre should also be monitored (causative organisms and sensitivities); some guidelines recommend these reviews at least on an annual basis.<span class="elsevierStyleSup">5</span></p><p class="elsevierStylePara">At our institution, we performed a retrospective study in June 2008 of the cases of peritonitis that occurred between January 2006 and June 2008. In this period, it was observed that the resistance of gram-negative bacteria to ampicillin was increasing progressively, reaching 77% in 2008.<span class="elsevierStyleSup">6</span> Given these results, we decided to replace ampicillin and tobramycin with oral ciprofloxacin in our treatment protocol (ampicillin, tobramycin, vancomycin, and fluconazole), according to the recommendations of the Spanish Society of Nephrology [SEN, for its initials in Spanish] from 2004), since the sensitivity to this drug during the same time period was practically 100%.</p><p class="elsevierStylePara">Given the increase of cases of peritonitis from gram-negative bacteria, our institution also decided in February 2009 to change the protocol for treating the outflow orifices of peritoneal catheters to the application of topical gentamicin once per day. The primary objective of this modification was to prevent cases of peritonitis caused by gram-negative bacteria, avoiding the colonisation and infection by gram-negative bacteria of the peritoneal catheter outflow orifice.</p><p class="elsevierStylePara">In this context, we carried out a retrospective analysis of all cases of peritonitis that occurred at our centre during 2009-2010 in order to evaluate the results of the changes mentioned to the treatment protocols. The micro-organisms responsible for the infections are compiled in Table 1.</p><p class="elsevierStylePara">In this study, we have focused on analysing the percentage of cases of peritonitis caused by gram-negative bacteria and the resistance these infections have to our empirical treatment protocol, comparing this data from the 2007-2008 study, which were from before the protocols were modified. We also calculated and compared ratios of peritonitis/patient and year.</p><p class="elsevierStylePara">As shown in Figure 1, the results have been favourable since the changes in treatment protocols. Cases of peritonitis caused by gram-negative bacteria decreased by 17.5% in 2009 and 26.5% in 2010, and the resistance of these bacteria to ciprofloxacin decreased by 14.3% and 33.3%, respectively.</p><p class="elsevierStylePara">The ratio of cases of peritonitis/patient and year were 0.65 in 2009 and 0.6 in 2010, which is an improvement over the results from 2007 and 2008 (1.01 and 0.86, respectively).</p><p class="elsevierStylePara">Another result that highlights the new treatment in caring for the outflow orifice is that the same micro-organism was encountered both in the outflow orifice and from cultures of the peritoneal fluid in only 7 cases, and 100% of these were gram-positive bacteria.</p><p class="elsevierStylePara">In our opinion, these data support the idea that performing periodical reviews of treatment protocols and sensitivities to medication at each centre is a very important tool, both in the prevention and treatment of infectious complications of PD.</p><p class="elsevierStylePara"><span class="elsevierStyleBold">Conflicts of interest</span></p><p class="elsevierStylePara">The authors have no conflicts of interest to declare.</p><p class="elsevierStylePara"><a href="grande/11003_108_25061_en_11003_t1.jpg" class="elsevierStyleCrossRefs"><img src="11003_108_25061_en_11003_t1.jpg" alt="Micro-organisms responsible for cases of peritonitis in 2009 and 2010 "></img></a></p><p class="elsevierStylePara">Table 1. Micro-organisms responsible for cases of peritonitis in 2009 and 2010 </p><p class="elsevierStylePara"><a href="grande/11003_108_25062_en_11003_f1.jpg" class="elsevierStyleCrossRefs"><img src="11003_108_25062_en_11003_f1.jpg" alt="Description of the ratio of peritonitis/patients and year, percentage of peritonitis due to gram-negative bacteria, and resistance to antibiotic treatment. Comparison of the two-year period of 2007-2009 and 2009-2010"></img></a></p><p class="elsevierStylePara">Figure 1. Description of the ratio of peritonitis/patients and year, percentage of peritonitis due to gram-negative bacteria, and resistance to antibiotic treatment. Comparison of the two-year period of 2007-2009 and 2009-2010</p>" "pdfFichero" => "P1-E528-S3223-A11003-EN.pdf" "tienePdf" => true "PalabrasClave" => array:1 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec439510" "palabras" => array:1 [ 0 => "Peritonitis" ] ] ] ] "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig1" "etiqueta" => "Tab. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11003_108_25061_en_11003_t1.jpg" "Alto" => 472 "Ancho" => 600 "Tamanyo" => 185858 ] ] "descripcion" => array:1 [ "en" => "Micro-organisms responsible for cases of peritonitis in 2009 and 2010" ] ] 1 => array:8 [ "identificador" => "fig2" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11003_108_25062_en_11003_f1.jpg" "Alto" => 201 "Ancho" => 600 "Tamanyo" => 98153 ] ] "descripcion" => array:1 [ "en" => "Description of the ratio of peritonitis/patients and year, percentage of peritonitis due to gram-negative bacteria, and resistance to antibiotic treatment. Comparison of the two-year period of 2007-2009 and 2009-2010" ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Troidle L, Gorban-Brennan N, Kliger A, Finkelstein F. Continuous peritoneal dialysis associated peritonitis: a review and current concepts. Semin Dial 2003;16:428-37. <a href="http://www.ncbi.nlm.nih.gov/pubmed/14629601" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Kim DK, Yoo TH, Ryu DR, Xu ZG, Kim HJ, Choi KH, et al. Changes in causative organisms and their antimicrobial susceptibilities in CAPD peritonitis: a single experience over one decade. Perit Dial Int 2004;24:424-32. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15490981" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Szeto CC, Chou KM, Leung CB, Wong TY, Wu AK, Wang AY. Clinical course of peritonitis due to pseudomonas species complicating peritoneal dialysis: a review of 104 cases. Kidney Int 2001;59:2309-15. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11380835" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Szeto CC, Chow VY, Chow KM, Lai RM, Chung KY, Leung CB, et al. Enterobacteriaceae peritonitis complicating peritoneal dialysis: a review of 210 consecutive cases. Kidney Int 2006;69:1245-52. <a href="http://www.ncbi.nlm.nih.gov/pubmed/16467787" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Li PK, Szeto CC, Piraino B, Bernardini J, Figueiredo AE, Gupta A, et al.\u{A0}Peritoneal dialysis-related infections recommendations: 2010 update. Perit Dial Int 2010;30:393-423. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20628102" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Novoa E, Pérez C, Borrajo M, Santos J. Individualización del protocolo de peritonitis en diálisis peritoneal. Nefrologia 2009;29(1):85-6. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19240782" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000003100000006/v0_201502091623/X2013251411000137/v0_201502091623/en/main.assets" "Apartado" => array:4 [ "identificador" => "35438" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor - Brief papers about basic research or clinical experiences" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003100000006/v0_201502091623/X2013251411000137/v0_201502091623/en/P1-E528-S3223-A11003-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251411000137?idApp=UINPBA000064" ]
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2024 May | 52 | 28 | 80 |
2024 April | 54 | 37 | 91 |
2024 March | 63 | 18 | 81 |
2024 February | 49 | 41 | 90 |
2024 January | 41 | 26 | 67 |
2023 December | 34 | 23 | 57 |
2023 November | 37 | 33 | 70 |
2023 October | 45 | 28 | 73 |
2023 September | 27 | 31 | 58 |
2023 August | 28 | 18 | 46 |
2023 July | 43 | 28 | 71 |
2023 June | 40 | 25 | 65 |
2023 May | 33 | 34 | 67 |
2023 April | 26 | 10 | 36 |
2023 March | 33 | 12 | 45 |
2023 February | 40 | 20 | 60 |
2023 January | 22 | 16 | 38 |
2022 December | 45 | 36 | 81 |
2022 November | 55 | 36 | 91 |
2022 October | 53 | 37 | 90 |
2022 September | 53 | 36 | 89 |
2022 August | 44 | 43 | 87 |
2022 July | 29 | 47 | 76 |
2022 June | 46 | 29 | 75 |
2022 May | 61 | 23 | 84 |
2022 April | 47 | 52 | 99 |
2022 March | 55 | 42 | 97 |
2022 February | 27 | 43 | 70 |
2022 January | 28 | 28 | 56 |
2021 December | 34 | 34 | 68 |
2021 November | 34 | 37 | 71 |
2021 October | 62 | 34 | 96 |
2021 September | 61 | 35 | 96 |
2021 August | 34 | 48 | 82 |
2021 July | 87 | 18 | 105 |
2021 June | 32 | 28 | 60 |
2021 May | 34 | 36 | 70 |
2021 April | 82 | 34 | 116 |
2021 March | 66 | 37 | 103 |
2021 February | 51 | 18 | 69 |
2021 January | 50 | 16 | 66 |
2020 December | 34 | 15 | 49 |
2020 November | 26 | 10 | 36 |
2020 October | 25 | 16 | 41 |
2020 September | 12 | 3 | 15 |
2020 August | 32 | 16 | 48 |
2020 July | 24 | 9 | 33 |
2020 June | 20 | 11 | 31 |
2020 May | 40 | 7 | 47 |
2020 April | 20 | 18 | 38 |
2020 March | 38 | 13 | 51 |
2020 February | 24 | 18 | 42 |
2020 January | 28 | 22 | 50 |
2019 December | 30 | 11 | 41 |
2019 November | 31 | 23 | 54 |
2019 October | 16 | 7 | 23 |
2019 September | 30 | 24 | 54 |
2019 August | 15 | 9 | 24 |
2019 July | 28 | 25 | 53 |
2019 June | 26 | 11 | 37 |
2019 May | 26 | 10 | 36 |
2019 April | 92 | 29 | 121 |
2019 March | 33 | 15 | 48 |
2019 February | 27 | 14 | 41 |
2019 January | 38 | 19 | 57 |
2018 December | 70 | 34 | 104 |
2018 November | 113 | 16 | 129 |
2018 October | 98 | 8 | 106 |
2018 September | 92 | 34 | 126 |
2018 August | 69 | 23 | 92 |
2018 July | 44 | 16 | 60 |
2018 June | 52 | 11 | 63 |
2018 May | 56 | 14 | 70 |
2018 April | 68 | 9 | 77 |
2018 March | 53 | 11 | 64 |
2018 February | 52 | 5 | 57 |
2018 January | 55 | 10 | 65 |
2017 December | 49 | 6 | 55 |
2017 November | 42 | 8 | 50 |
2017 October | 23 | 6 | 29 |
2017 September | 33 | 7 | 40 |
2017 August | 40 | 4 | 44 |
2017 July | 39 | 5 | 44 |
2017 June | 48 | 7 | 55 |
2017 May | 56 | 3 | 59 |
2017 April | 44 | 5 | 49 |
2017 March | 39 | 2 | 41 |
2017 February | 30 | 2 | 32 |
2017 January | 26 | 7 | 33 |
2016 December | 44 | 8 | 52 |
2016 November | 46 | 9 | 55 |
2016 October | 63 | 11 | 74 |
2016 September | 105 | 1 | 106 |
2016 August | 191 | 5 | 196 |
2016 July | 181 | 6 | 187 |
2016 June | 108 | 0 | 108 |
2016 May | 116 | 0 | 116 |
2016 April | 80 | 0 | 80 |
2016 March | 83 | 0 | 83 |
2016 February | 101 | 0 | 101 |
2016 January | 103 | 0 | 103 |
2015 December | 88 | 0 | 88 |
2015 November | 85 | 0 | 85 |
2015 October | 97 | 0 | 97 |
2015 September | 55 | 0 | 55 |
2015 August | 65 | 0 | 65 |
2015 July | 57 | 0 | 57 |
2015 June | 39 | 0 | 39 |
2015 May | 54 | 0 | 54 |
2015 April | 7 | 0 | 7 |