array:21 [
  "pii" => "X2013251409005088"
  "issn" => "20132514"
  "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
  "estado" => "S300"
  "fechaPublicacion" => "2009-02-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia (English Version). 2009;29:30-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5608
    "formatos" => array:3 [
      "EPUB" => 251
      "HTML" => 4560
      "PDF" => 797
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699509005080"
      "issn" => "02116995"
      "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
      "estado" => "S300"
      "fechaPublicacion" => "2009-02-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2009;29:30-4"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 29772
        "formatos" => array:3 [
          "EPUB" => 246
          "HTML" => 27588
          "PDF" => 1938
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "titulo" => "Longitud renal por ultrasonografía en población mexicana adulta"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "30"
            "paginaFinal" => "34"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Renal length by ultrasound in Mexican adults"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Justo Oyuela-Carrasco, Franciso Rodríguez-Castellanos, Eric Kimura, Rosa Elena Delgado, Juan Pablo Herrera-Felix"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Justo"
                "apellidos" => "Oyuela-Carrasco"
              ]
              1 => array:2 [
                "nombre" => "Franciso"
                "apellidos" => "Rodríguez-Castellanos"
              ]
              2 => array:2 [
                "nombre" => "Eric"
                "apellidos" => "Kimura"
              ]
              3 => array:2 [
                "nombre" => "Rosa Elena"
                "apellidos" => "Delgado"
              ]
              4 => array:2 [
                "nombre" => "Juan Pablo"
                "apellidos" => "Herrera-Felix"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251409005088"
          "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005088?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005080?idApp=UINPBA000064"
      "url" => "/02116995/0000002900000001/v0_201502091413/X0211699509005080/v0_201502091413/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251409005096"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.2009.29.1.35.1.en.full.pdf"
    "estado" => "S300"
    "fechaPublicacion" => "2009-02-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2009;29:35-41"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3513
      "formatos" => array:3 [
        "EPUB" => 222
        "HTML" => 2765
        "PDF" => 526
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "Morphometric and immunohistochemical insight into focal segmental glomerulosclerosis in obese and non-obese patients."
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "35"
          "paginaFinal" => "41"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier España"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "22918078_t1_p36.jpg"
              "Alto" => 121
              "Ancho" => 827
              "Tamanyo" => 17277
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Clinical and laboratory findings at the time of biopsy in cases with O-FSGS and I-FSGS"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marian Danilewicz, Malgorzata Wagrowska-Danielwicz"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Marian"
              "apellidos" => "Danilewicz"
            ]
            1 => array:2 [
              "nombre" => "Malgorzata"
              "apellidos" => "Wagrowska-Danielwicz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "X0211699509005099"
        "doi" => "10.3265/Nefrologia.2009.29.1.35.1.en.full.pdf"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005099?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005096?idApp=UINPBA000064"
    "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005096/v0_201502091633/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251409005135"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.2009.29.1.20.1.en.full.pdf"
    "estado" => "S300"
    "fechaPublicacion" => "2009-02-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2009;29:20-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4121
      "formatos" => array:3 [
        "EPUB" => 214
        "HTML" => 3440
        "PDF" => 467
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "titulo" => "Metabolic syndrome and living renal donation: is this syndrome a contraindication for donation?"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "20"
          "paginaFinal" => "29"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Síndrome metabólico y donación renal de vivo: ¿contraindica la donación este síndrome?"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier España"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "22518078_t1_p21.jpg"
              "Alto" => 416
              "Ancho" => 827
              "Tamanyo" => 59876
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Clinical criteria for diagnosis of metabolic syndrome according to ATPIII-NCEP criteria (The Adult Panel of the National Cholesterol Education Program) and the World Health Organization (WHO)"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Domingo Hernandez, Alejandra Alvarez, Ana Maria Armas, Margarita Rufino, Esteban Porrini, Armando Torres"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Domingo"
              "apellidos" => "Hernandez"
            ]
            1 => array:2 [
              "nombre" => "Alejandra"
              "apellidos" => "Alvarez"
            ]
            2 => array:2 [
              "nombre" => "Ana Maria"
              "apellidos" => "Armas"
            ]
            3 => array:2 [
              "nombre" => "Margarita"
              "apellidos" => "Rufino"
            ]
            4 => array:2 [
              "nombre" => "Esteban"
              "apellidos" => "Porrini"
            ]
            5 => array:2 [
              "nombre" => "Armando"
              "apellidos" => "Torres"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699509005138"
        "doi" => "10.3265/Nefrologia.2009.29.1.20.1.en.full.pdf"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005138?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005135?idApp=UINPBA000064"
    "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005135/v0_201502091633/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "titulo" => "Renal length by ultrasound in Mexican adults"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "30"
        "paginaFinal" => "34"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Justo Oyuela-Carrasco, Franciso Rodríguez-Castellanos, Eric Kimura, Rosa Elena Delgado, Juan Pablo Herrera-Felix"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Justo"
            "apellidos" => "Oyuela-Carrasco"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Franciso"
            "apellidos" => "Rodr&#237;guez-Castellanos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Eric"
            "apellidos" => "Kimura"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Rosa Elena"
            "apellidos" => "Delgado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Juan Pablo"
            "apellidos" => "Herrera-Felix"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Departamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chavez Cuidad de México, México, México, "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Longitud renal por ultrasonograf&#237;a en poblaci&#243;n mexicana adulta"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig1"
        "etiqueta" => "Fig. 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f1_p32.jpg"
            "Alto" => 312
            "Ancho" => 397
            "Tamanyo" => 12689
          ]
        ]
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">INTRODUCTION</span></p><p class="elsevierStylePara">Renal length estimation by ultrasound is an important parameter in clinical evaluation of adult patients kidney disease and healthy adult donors<span class="elsevierStyleSup">1&#44;2</span> and has replaced radiography as the common standard&#46; Ultrasound is a useful&#44; accessible&#44; non-invasive&#44; inexpensive method to reliably measure renal size&#46;<span class="elsevierStyleSup">3</span></p><p class="elsevierStylePara">Some renal diseases can change the morphological characteristics of the kidney seen by ultrasound&#46; Renal size can also be a decisive factor for performing renal biopsy or avoiding immunosuppressive therapy&#46;<span class="elsevierStyleSup">2</span> Estimating renal size by ultrasound can be done by measuring the length&#44; total volume or cortical thickness&#46; The most accurate measurement of renal size is the total renal volume&#44; which is correlated with height&#44; weight and total body area&#46; This measurement requires expensive&#44; highly complex studies with specific protocols&#44; such as axial tomography and magnetic resonance&#46; However&#44; renal length has also been shown to be a reliable parameter<span class="elsevierStyleSup">2</span> with a high level of interand intra-observer reproducibility in comparison to volumetric renal estimation&#44; which correlates appropriately with function and different anthropometric variables&#46;<span class="elsevierStyleSup">4</span></p><p class="elsevierStylePara">Renal size depends on different factors&#44; which include size&#44; body mass index and gender&#46; However&#44; race has particular connotations&#44; which directly determines all the previous variables&#46; The change in renal size can be very suggestive evidence of disease&#44; whose interpretation requires specific parameters for the population to study&#46; It is therefore necessary to have benchmark parameters in our population group&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">MATERIALS AND METHODS</span></p><p class="elsevierStylePara">Prospective observational study carried out during the period between April and June 2008&#46; An ultrasound screening was carried out on 153 healthy volunteers who complied with the following criteria for inclusion&#58; serum creatinin &#8804; 1&#46;5mg&#47;dl&#44; glycaemia &#8804; 110mg&#47;dl in patients aged over 40 years or with BMI &#62; 30kg&#47;mt<span class="elsevierStyleSup">2</span>&#44; arterial normotensive &#40;systolic blood pressure &#60; 140mmHg and diastolic blood pressure &#60; 90mmHg&#41;&#44; no existence of acute or chronic disease capable of causing damage to renal function and normal appearance of the kidneys by ultrasound &#40;thickness of renal parenchyma &#62; 1cm and corticomedullary ratio detectable by ultrasound&#46;&#41; Patients with the following conditions were excluded&#58; cysts greater than 4cm&#44; polycystic kidney disease&#44; multiple cysts &#40;&#62; 4&#41;&#44; sole kidney&#44; hydronephrosis&#44; poor ultrasound examination window &#40;automatically elevated kidney&#44; with interference in costal arches&#41;&#44; pregnancy&#44; extreme obesity&#44; renal tumours and horseshoe kidney&#46;</p><p class="elsevierStylePara">Height was measured without shoes or hat&#44; using a stadiometer&#46; The ultrasound measurement was made by a single observer&#44; using a TITAN Sonosite high resolution device&#44; with a 3&#46;5MHz convex transductor&#46; All the participants emptied their bladders prior to the examination&#44; to avoid an increase in renal length caused by oral hydration&#46;<span class="elsevierStyleSup">5</span> Renal length was measured as the longest longitudinal diameter&#44; with the patient fasting and in three positions &#40;supine&#44; supine lateral and prone&#46;&#41; Three measurements were taken for each kidney&#44; registering the longest length in absolute terms&#46;</p><p class="elsevierStylePara">The results were expressed as an average &#43; DS&#46; The averages of the different numerical variables were compared by gender using the t-Student test for independent samples&#46; An association test was performed between the different renal lengths and the anthropometric variables using the Pearson correlation coefficient&#46; Finally&#44; the total student population was divided into age groups with 10-year intervals and a comparison was LRL and RRL between the different age groups using a one-way analysis of variance&#44; followed by Bonferroni&#8217;s multiple-comparison test &#40;<span class="elsevierStyleItalic">post hoc</span>&#46;&#41; A value of p &#60; 0&#46;05 was considered statistically significant&#46; The SPSS version 15 statistical packet for Windows was used&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">RESULTS</span></p><p class="elsevierStylePara">A total of 157 subjects were included&#44; four of whom were excluded due to the presence of solid cysts over 4cm long &#40;two subjects&#41;&#44; morbid obesity &#40;one subject&#41; and one case with a very thin renal cortex &#40;&#60; 1cm&#41;&#46; Of the 153 individuals evaluated&#44; 77 were male and 76 female&#44; with an average age of 46&#46;12 &#43; 15&#46;44 years &#40;range between 20 and 79 years&#46;&#41; The average for the different anthropometric measurements in the total study population &#40;weight&#44; height and BMI&#41; was&#58; 68&#46;87 &#177; 11&#46;69kg&#44; 160 &#177; 8&#46;62cm and 26&#46;7 &#177; 3&#46;82kg&#47;mt<span class="elsevierStyleSup">2</span>&#44; respectively&#46; The left renal length in the total group was an average of 105&#46;8 &#177; 7&#46;56mm&#44; and the right renal length 104&#46;3 &#177; 6&#46;45mm &#40;p &#61; 0&#46;000&#46;&#41; With regard to the Cr S&#44; the average value for the total group 0&#46;86 &#177; 0&#46;17&#44; with a range of 0&#46;5 to 1&#46;3mg&#47;dl&#59; and specifically for the 60 to 70 years age group the average value was 0&#46;94 &#177; 0&#46;17&#44; with a range of 0&#46;63 to 1&#46;3mg&#47;dl&#46; The glomerular filtration for this age group&#44; estimated with the Cockroft-Gault formula&#44; corresponds to 66 &#177; 14&#46;8ml&#47;min&#44; with a range of 42 to 93ml&#47;min&#46;</p><p class="elsevierStylePara">When the study population was divided by gender&#44; the following data was found&#58; the average weight was 73&#46;77 &#177; 11&#46;29kg for males &#40;range of 52 to 111kg&#41; and 63&#46;9 &#177; 9&#46;90kg for women &#40;range of 43&#46;5 to 85kg&#41; &#40;p &#61; 0&#46;00&#46;&#41; The average height was 166 &#177; 6&#46;15cm for males &#40;range of 155 to 185cm&#41; and 154&#46;7 &#177; 5&#46;97cm for women &#40;range of 139 to 167cm&#41; &#40;p &#61; 0&#46;00&#46;&#41;</p><p class="elsevierStylePara">The average LRL in men was 107&#46;16 &#177; 6&#46;97mm &#40;range of 90 or 121mm&#41;&#44; and in women&#44; from 104&#46;6 &#177; 7&#46;96mm &#40;range from 88 to 122mm&#41; &#40;p &#61; 0&#46;036&#46;&#41; The average RRL in men was 105&#46;74 &#177; 5&#46;74mm &#40;range of 93 or 120mm&#41;&#44; and in women&#44; from 102&#46;99 &#177; 6&#46;85mm &#40;range from 89 to 120mm&#41; &#40;p &#61; 0&#46;008&#46;&#41;</p><p class="elsevierStylePara">When the total study population was divided up according to age groups &#40;group 1&#58; 20-29 years&#59; group 2&#58; 30-39 years&#59; group 3&#58; 40-49 years&#59; group 4&#58; 50-59 years&#59; group 5&#58; 60-69 years&#59; group 6&#58; 70-79 years&#41;&#44; and when their LRL are compared&#44; the following measurements were found by group&#58; 106 &#177; 6&#46;53mm &#40;range from 95 to 119mm&#41;&#44; 106&#46;9 &#177; 6&#46;20mm &#40;range from 93 to 119mm&#41;&#44; 107&#46;6 &#177; 8&#46;3mm &#40;range from 91 to 122mm&#41;&#44; 106 &#177; 6&#46;9mm &#40;range from 92 to 120mm&#41;&#44; 102&#46;9 &#177; 8mm &#40;range from 88 to 116mm&#41; and 99 &#177; 7&#46;92mm &#40;range from 89 to 118mm&#41; from groups 1 to 6&#44; respectively&#44; significantly different in form for 6 vs&#46; groups 2 and 3 &#40;p &#60; 0&#46;05&#41; &#40;table 1 and figure 1&#46;&#41;</p><p class="elsevierStylePara">With regard to the RRL&#44; the following measurements were observed per group&#58; 103 &#177; 6&#46;06mm &#40;range from 92 to 120mm&#41;&#44; 105 &#177; 5&#46;57mm &#40;range from 94 to 116mm&#41;&#44; 105&#46;8 &#177; 7mm &#40;range from 90 to 120mm&#41;&#44; 106 &#177; 6&#46;0mm &#40;range from 95 to 116mm&#41;&#44; 102 &#177; 6&#46;5mm &#40;range from 92 to 114mm&#41; y 100 &#177; 6&#46;93mm &#40;range from 89 to 110mm&#41; for groups 1 to 6&#44; respectively&#44; which were not significantly different &#40;p &#61; NS&#41; &#40;table 1&#46;&#41; The association test performed using the Pearson correlation coefficient showed a significant positive correlation between both renal lengths and the different anthropometric measurements &#40;weight&#44; BMI and height&#41;&#44; for the LRL &#40;r&#61;0&#46;516&#44; p&#61;0&#46;000&#59; r &#61; 0&#46;408&#59; p &#61; 0&#46;000&#59; and r &#61; 0&#46;260&#44; p &#61; 0&#46;001&#44; respectively&#41; and for the RRL &#40;r &#61; 0&#46;501&#44; p &#61; 0&#46;000&#59; r &#61; 0&#46;363&#44; p &#61; 0&#46;000&#59; and r &#61; 0&#46;289&#44; p &#61; 0&#46;000&#44; respectively&#41; &#40;table 2 and figure 2&#46;&#41;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">DISCUSSION</span></p><p class="elsevierStylePara">Renal disease can increase or decrease renal size&#44; and may or may not be accompanied by changes to the normal organ structure&#46; Ultrasound has been shown to be a diagnostic method for taking these measurements&#44; which offers the advantage of being a non-invasive&#44; innocuous method for the patient in comparison to other measurement methods such as simple radiography or intravenous urography&#44; which have also shown their effectiveness in renal size evaluation&#46;</p><p class="elsevierStylePara">Renal length and volume are important parameters in the clinical scenario&#46; Specifically&#44; renal length measurement is more valuable in adults due to its reproducibility and accuracy&#46; Because of this&#44; it is essential to know the normal limits of renal size in patients for the purposes of correctly interpreting the study&#46;</p><p class="elsevierStylePara">In this study a significant difference in weight and height was observed when gender comparisons were made &#40;p &#61; 0&#46;00&#46;&#41; At the same time&#44; gender-related differences related to the RL were confirmed&#44; showing that the length of both kidneys was significantly greater in men than in women&#46; Similar data to that shown in earlier studies has been shown&#44;<span class="elsevierStyleSup">8&#44;9</span> in contrast to the paediatric population&#44; where generally speaking no significant differences have been seen in renal length&#44; probably related to the size of the sample and the strength of each study&#46;<span class="elsevierStyleSup">10</span></p><p class="elsevierStylePara">It is of great relevance that the decrease in both renal lengths &#40;LRL&#44; RRL&#41; from 60 years&#44; which was significant from 70 years on&#44; mainly for the LRL &#40;p &#60; 0&#46;05&#41;&#44; while the renal lengths in subjects aged between 20 and 59 years remained relatively homogeneous&#46; Therefore&#44; it would appear that renal length decreases considerably with age and that the rate of decrease accelerates with age&#44; especially after 60 years&#44; but above all after 70 years&#46; Other authors have shown results&#44; showing that the length and renal volume in subjects aged between 30 to 60 years showed slight differences and a clear decrease in both parameters after 70 years&#46;<span class="elsevierStyleSup">9</span> In this context&#44; the changes in renal structure and shape that take place in human beings with age&#44; decreased renal mass and renal weight and size&#44; are well known&#46;<span class="elsevierStyleSup">11</span> Post mortem studies have shown that the weight of the kidney is between 250 and 270g in young adults&#44; which falls over the years to 200g in the ninth decade of life&#46;<span class="elsevierStyleSup">12</span> Factors such as glomerulosclerosis and tubulointerstitial fibrosis could lead to a decrease in renal size and weight&#44; as histological data reveals a decrease in the number of cortical glomerules by 30-50&#37; at the age of 70 years&#44; as well as observing a loss of glomerular lobulation&#44; increasing mesangial volume and glomerular collapse&#44; as well as intimal thickening hyalinosis of both the arteries and the arteriola&#46;<span class="elsevierStyleSup">13-15</span> The latter can be explained by a decrease in the proangiogenic vascular endothelial growth&#44; as well as an increase in the expression of the antiangiogenic factor thrombospondin 1&#44; as has been shown in elderly rats&#46; Among other factors associated as potential modulators of renal fibrosis in elderly animals&#44; angiotensin II has been mentioned&#44; which is the beta transformer growth factor &#40;TGF-&#946;&#41;&#44; changes in the expression de Nitrous Oxide &#40;NO&#41;&#44; final products of advanced glycosylation &#40;AGE&#41;&#44; oxidative stress and changes in lipids&#44; may be future targets to modulate the progression of sclerosis and the decrease in renal size&#46;<span class="elsevierStyleSup">12</span></p><p class="elsevierStylePara">The decrease in renal length at 60 years&#44; and in particular from 70 years&#44; was significant for LRL&#44; not for RRL&#44; which showed no significant difference between the age groups in our study&#44; in contrast to the results published by other authors&#46; The left kidney was significantly larger than the right&#44; which was similar to the results of the majority of studies published&#46; This difference could be explained by the fact that the liver is bigger than the spleen&#44; which means that the right kidney has less space to grow&#46; Another possible explanation is related to the shorter length of the left renal artery&#44; which increases blood flow to the left kidney&#44; with the corresponding increase with regard to the volume and size of the kidney&#46; Finally&#44; the height &#40;shorter in our population&#41; may limit the free longitudinal growth of both kidneys&#46;</p><p class="elsevierStylePara">On the other hand&#44; the two renal lengths correlate in a significantly positive manner with weight and BMI&#44; and weakly with height&#44; in contrast to other studies in adults where the strength of this association has been significantly greater with height&#46;<span class="elsevierStyleSup">8&#44;9</span> On the other hand&#44; in the paediatric population a greater association with renal length has been found with the average TFG with inulin6 and with body surface area&#46;<span class="elsevierStyleSup">16</span></p><p class="elsevierStylePara">We consider it pertinent to explore the association of renal lengths in the future&#44; or their sum &#40;total renal length&#41;&#44; with different anthropometric measurements&#44; as well as with renal function parameters&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">CONCLUSIONS</span></p><p class="elsevierStylePara">In conclusion&#44; LRL was significantly greater than RRL in our population&#44; and both renal lengths were greater in men than in women&#46; Renal size and height were shorter in this population in comparison with figures published in European populations&#46; A fall in the RL was observed with age&#44; especially after 60 years&#44; but significantly after the age of 70 years&#46; Both RL correlated positively with weight&#44; the BMI and height&#46;</p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;f1&#95;p32&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_f1_p32.jpg"></img></a></p><p class="elsevierStylePara">Figure 1&#46; </p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;t1&#95;p32&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_t1_p32.jpg" alt="Distribution of renal length according to age group &#40;years&#41;"></img></a></p><p class="elsevierStylePara">Table 1&#46; Distribution of renal length according to age group &#40;years&#41;</p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;f2&#95;p33&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_f2_p33.jpg"></img></a></p><p class="elsevierStylePara">Figure 2&#46; </p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;t2&#95;p33&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_t2_p33.jpg" alt="Correlation of anthropometric measurements with renal length"></img></a></p><p class="elsevierStylePara">Table 2&#46; Correlation of anthropometric measurements with renal length</p>"
    "pdfFichero" => "P-E-S-A228-EN.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:2 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440355"
          "palabras" => array:1 [
            0 => "Longitud renal"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440357"
          "palabras" => array:1 [
            0 => "Ultrasonido renal"
          ]
        ]
      ]
      "en" => array:2 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440356"
          "palabras" => array:1 [
            0 => "Renal length"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440358"
          "palabras" => array:1 [
            0 => "Renal ultrasound"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<p class="elsevierStylePara">Introducci&#243;n&#58; la estimaci&#243;n del tama&#241;o renal por ultrasonograf&#237;a es un par&#225;metro importante en la evaluaci&#243;n cl&#237;nica y en el manejo de pacientes adultos con enfermedad renal y adultos sanos donadores&#46; El cambio en el tama&#241;o renal puede ser una evidencia muy sugerente de enfermedad&#44; por lo que su interpretaci&#243;n requiere de par&#225;metros espec&#237;ficos para la poblaci&#243;n a estudiar&#46; En el caso de Am&#233;rica Latina&#44; no se han descrito par&#225;metros normales&#46; Objetivo&#58; describir par&#225;metros normales de Longitud Renal &#40;LR&#41; por ultrasonograf&#237;a en una poblaci&#243;n mexicana adulta&#46; M&#233;todos&#58; medici&#243;n ultrasonogr&#225;fica de LR en 153 adultos sanos estratificados por edad&#46; Se investig&#243; la posible asociaci&#243;n de la LR con par&#225;metros antropom&#233;tricos&#46; Resultados&#58; se estudiaron 77 varones y 76 mujeres&#59; la edad promedio fue de 44&#44;12 &#177; 15&#44;44 a&#241;os&#46; El promedio de peso&#44; &#205;ndice de Masa Corporal &#40;IMC&#41; y talla fue de 68&#44;87 &#177; 11&#44;69 kg&#44; 26&#44;77 &#177; 3&#44;82 kg&#47;m2 y 160 &#177; 8&#44;62 cm&#44; respectivamente&#46; Al dividir a la poblaci&#243;n estudiada por g&#233;nero&#44; encontramos que la talla fue de 166 &#177; 6&#44;15 cm para varones y 154&#44;7 &#177; 5&#44;97 cm para mujeres&#44; &#40;p &#61; 0&#44;00&#41;&#46; La Longitud Renal Izquierda &#40;LRI&#41; en el grupo total fue de 105&#44;8 &#177; 7&#44;56 mm&#44; y la Longitud Renal Derecha &#40;LRD&#41;&#44; de 104&#44;3 &#177; 6&#44;45 mm &#40;p &#61; 0&#44;000&#41;&#46; La LRI en varones fue de 107&#44;16 &#177; 6&#44;97 mm&#44; y en mujeres&#44; de 104&#44;6 &#177; 7&#44;96 mm&#46; La media de la LRD en varones fue de 105&#44;74 &#177; 5&#44;74 mm y en mujeres&#44; de 102&#44;99 &#177; 6&#44;85 mm&#44; &#40;p &#61; 0&#44;008&#41;&#46; La LR disminuy&#243; con la edad&#44; y la tasa de disminuci&#243;n parece aumentar despu&#233;s de los 60 a&#241;os&#46; Las LR se correlacionaron de forma significativa y positiva con el peso&#44; el IMC y la talla&#46; Conclusiones&#58; la LR fue significativamente mayor en varones que en mujeres para ambos ri&#241;ones &#40;p &#61; 0&#44;036&#41;&#46; La LR disminuy&#243; continuamente con la edad&#44; especialmente despu&#233;s de los 60 a&#241;os y de forma significativa despu&#233;s de los 70 a&#241;os&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<p class="elsevierStylePara">Introduction&#58; Renal length estimation by ultrasound is an important parameter in clinical evaluation of kidney disease and healthy donors&#46; Changes in renal volume may be a sign of kidney disease&#46; Correct interpretation of renal length requires the knowledge of normal limits&#44; these have not been described for Latin American population&#46; Objective&#58; To describe normal renal length &#40;RL&#41; by ultrasonography in a group of Mexican adults&#46; Methods&#58; Ultrasound measure of RL in 153 healthy Mexican adults stratified by age&#46; Describe the association of RL to several anthropometric variables&#46; Results&#58; A total of 77 males and 76 females were scanner&#46; The average age for the group was 44&#46;12 &#177; 15&#46;44 years&#46; The mean weight&#44; body mass index &#40;BMI&#41; and height were 68&#46;87 &#177; 11&#46;69 Kg&#44; 26&#46;77 &#177; 3&#46;82 kg&#47;m2 and 160 &#177; 8&#46;62 cm respectively&#46; Dividing the population by gender&#44; showed a height of 166 &#177; 6&#46;15 cm for males and 154&#46;7 &#177; 5&#46;97 cm for females &#40;p &#61;0&#46;00&#41;&#46; Left renal length &#40;LRL&#41; in the whole group was 105&#46;8 &#177; 7&#46;56 mm and right renal length &#40;RRL&#41; was 104&#46;3 &#177; 6&#46;45 mm &#40;p &#61; 0&#46;000&#41;&#46; The LRL for males was 107&#46;16 &#177; 6&#46;97 mm and for females was 104&#46;6 &#177; 7&#46;96 mm&#46; The average RRL for males was 105&#46;74 &#177; 5&#46;74 mm and for females 102&#46;99 &#177; 6&#46;85 mm &#40;p &#61; 0&#46;008&#41;&#46; We noted that RL decreased with age and the rate of decline accelerates alter 60 years of age&#46; Both lengths correlated significantly and positively with weight&#44; BMI and height&#46; Conclusions&#58; The RL was significantly larger in males than in females in both kidneys &#40;p &#61; 0&#46;036&#41; in this Mexican population&#46; Renal length declines after 60 years of age and specially after 70 years&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:7 [
        "identificador" => "fig1"
        "etiqueta" => "Fig. 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f1_p32.jpg"
            "Alto" => 312
            "Ancho" => 397
            "Tamanyo" => 12689
          ]
        ]
      ]
      1 => array:8 [
        "identificador" => "fig2"
        "etiqueta" => "Tab.  1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_t1_p32.jpg"
            "Alto" => 172
            "Ancho" => 827
            "Tamanyo" => 30525
          ]
        ]
        "descripcion" => array:1 [
          "en" => "Distribution of renal length according to age group &#40;years&#41;"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig3"
        "etiqueta" => "Fig. 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f2_p33.jpg"
            "Alto" => 277
            "Ancho" => 397
            "Tamanyo" => 16452
          ]
        ]
      ]
      3 => array:8 [
        "identificador" => "fig4"
        "etiqueta" => "Tab.  2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_t2_p33.jpg"
            "Alto" => 119
            "Ancho" => 400
            "Tamanyo" => 11031
          ]
        ]
        "descripcion" => array:1 [
          "en" => "Correlation of anthropometric measurements with renal length"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:1 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "- Yong Kang K, Joon Lee Y, Chul Park S, Woo Yang C, Soo Kim Y, Sung Moom I, Bok Koh Y, Kee Bang B, Soon Choi B. A comparative study of methods of estimating kidney length in kidney transplantation donors. Nephrol Dial Transplant. 2007, 22(8): 2322-2327.2. - Ablett MJ, Coulthard A, Lee RE, et al: How reliableare ultrasound measurements of renal length inadults? Br J Radiol 1995; 68:1087- 1089.3. - GavelaT, Sánchez Bayle M, Gómez Mardones G, Gallego S, Martínez-Pérez J, Moya MT, Ecographic study of kidney size in children. Nefrologia, 2006;26 (3): 325-9.4. - Emanan SA, Nielsen MB, Pedersen JF, Intraobserver and interobserver variations in sonographic measurements of kidney size in adults volunteers. A comparison of linear measurements and volumetric estimates. Acta Radiol 1995: 36 (4) 399-401. \u{A0}5.- Kantarci F, Mihmanli I, Adaleti I, Ozer H, Gulsen F, Kadioglu A, Altug A, Uysal O: The effect of fluid on renal length measurement in adults: Journal of Clinical Ultrasound. 2006; 34 (3): 128-1336.- Adibi, Khosravi. Do kidney sizes in ultrasonography correlate to glomerular filtration rate in healthy children?. Australasian Radiology,Dec 2007; 51(6): 555-595\u{A0}7.- Van Den Noortgate N, Velghe A, Petrovic M et al. The role of ultrasonography in the assessment of renal function in the elderly. J Nephrol 2003; 16: 658-628.-Miletic D, Fuckar Z, Sustic A, Mozetic V, Stimac D,Zauhar G: Sonographic measurement of absolute and relativerenal length in adults. J Clin Ultrasound. 1998; 26:185-189.9. - Emamian SA, Nielsen MB, Pedersen JF, et al: Kidneydimensions at sonography: correlation withage, sex, and habitus in 665 adult volunteers. AJRAm J Roentgenol 1993; 160:83.10.- Ece A, Gözü A, Bükte Y, Tutanc M, Kocamaz H. The effect of malnutrition on kidney size in children. Pediatr Nephrol. 2007; 22(6): 857-6311.- Gourtsoyiannis N, Prassopoulos P, Cavouras D, Pantelidis N: The thickness of the renal parenchyma decreases with age: A CT study of 360 patients. AJR Am J Roentgenol 1990; 155:541-544.12.- Brenner and Rector's The Kidney. 8th ed. Philadelphia, Pa: Saunders; 2008. P 686\u{A0}13.-Tracy RE, Berenson G, Wattigney W, Barrett TJ: The evolution of benign arterionephrosclerosis from age 6 to 70 years. Am J Pathol 1990; 136:429-439.\u{A0}14. - Melk A, Halloran PF: Cell senescence and its implications for nephrology. J Am Soc Nephrol 2001; 12:385-393.\u{A0}15. - Hill GS, Heudes D, Bariety J: Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulation. Kidney Int 2003; 63:1027-1036.16. - Wilson BE, Davies P, Shah K, Wong W, Taylor CM. Renal length and inulin in the radiologically single kidney. Pediatr Nephrol. 2003; 18(11): 1147-51."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:1 [
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109711017025"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005088/v0_201502091633/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35441"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originals"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002900000001/v0_201502091632/X2013251409005088/v0_201502091633/en/P-E-S-A228-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005088?idApp=UINPBA000064"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Renal length by ultrasound in Mexican adults
Longitud renal por ultrasonografía en población mexicana adulta
Justo Oyuela-Carrascoa, Franciso Rodríguez-Castellanosa, Eric Kimuraa, Rosa Elena Delgadoa, Juan Pablo Herrera-Felixa
a Departamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chavez Cuidad de México, México, México,
Read
11434
Times
was read the article
2720
Total PDF
8714
Total HTML
Share statistics
 array:21 [
  "pii" => "X2013251409005088"
  "issn" => "20132514"
  "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
  "estado" => "S300"
  "fechaPublicacion" => "2009-02-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia &#40;English Version&#41;. 2009;29:30-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 5608
    "formatos" => array:3 [
      "EPUB" => 251
      "HTML" => 4560
      "PDF" => 797
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699509005080"
      "issn" => "02116995"
      "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
      "estado" => "S300"
      "fechaPublicacion" => "2009-02-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2009;29:30-4"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 29772
        "formatos" => array:3 [
          "EPUB" => 246
          "HTML" => 27588
          "PDF" => 1938
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "titulo" => "Longitud renal por ultrasonograf&#237;a en poblaci&#243;n mexicana adulta"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "30"
            "paginaFinal" => "34"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Renal length by ultrasound in Mexican adults"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Justo Oyuela-Carrasco, Franciso Rodr&#237;guez-Castellanos, Eric Kimura, Rosa Elena Delgado, Juan Pablo Herrera-Felix"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Justo"
                "apellidos" => "Oyuela-Carrasco"
              ]
              1 => array:2 [
                "nombre" => "Franciso"
                "apellidos" => "Rodr&#237;guez-Castellanos"
              ]
              2 => array:2 [
                "nombre" => "Eric"
                "apellidos" => "Kimura"
              ]
              3 => array:2 [
                "nombre" => "Rosa Elena"
                "apellidos" => "Delgado"
              ]
              4 => array:2 [
                "nombre" => "Juan Pablo"
                "apellidos" => "Herrera-Felix"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251409005088"
          "doi" => "10.3265/Nefrologia.2009.29.1.30.1.en.full.pdf"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005088?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005080?idApp=UINPBA000064"
      "url" => "/02116995/0000002900000001/v0_201502091413/X0211699509005080/v0_201502091413/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251409005096"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.2009.29.1.35.1.en.full.pdf"
    "estado" => "S300"
    "fechaPublicacion" => "2009-02-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2009;29:35-41"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3513
      "formatos" => array:3 [
        "EPUB" => 222
        "HTML" => 2765
        "PDF" => 526
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "Morphometric and immunohistochemical insight into focal segmental glomerulosclerosis in obese and non-obese patients&#46;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "35"
          "paginaFinal" => "41"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier Espa&#241;a"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "22918078_t1_p36.jpg"
              "Alto" => 121
              "Ancho" => 827
              "Tamanyo" => 17277
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Clinical and laboratory findings at the time of biopsy in cases with O-FSGS and I-FSGS"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marian Danilewicz, Malgorzata Wagrowska-Danielwicz"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Marian"
              "apellidos" => "Danilewicz"
            ]
            1 => array:2 [
              "nombre" => "Malgorzata"
              "apellidos" => "Wagrowska-Danielwicz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "X0211699509005099"
        "doi" => "10.3265/Nefrologia.2009.29.1.35.1.en.full.pdf"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005099?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005096?idApp=UINPBA000064"
    "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005096/v0_201502091633/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251409005135"
    "issn" => "20132514"
    "doi" => "10.3265/Nefrologia.2009.29.1.20.1.en.full.pdf"
    "estado" => "S300"
    "fechaPublicacion" => "2009-02-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2009;29:20-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4121
      "formatos" => array:3 [
        "EPUB" => 214
        "HTML" => 3440
        "PDF" => 467
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "titulo" => "Metabolic syndrome and living renal donation&#58; is this syndrome a contraindication for donation&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "20"
          "paginaFinal" => "29"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome metab&#243;lico y donaci&#243;n renal de vivo&#58; &#191;contraindica la donaci&#243;n este s&#237;ndrome&#63;"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig1"
          "etiqueta" => "Tab.  1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "copyright" => "Elsevier Espa&#241;a"
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "22518078_t1_p21.jpg"
              "Alto" => 416
              "Ancho" => 827
              "Tamanyo" => 59876
            ]
          ]
          "descripcion" => array:1 [
            "en" => "Clinical criteria for diagnosis of metabolic syndrome according to ATPIII-NCEP criteria &#40;The Adult Panel of the National Cholesterol Education Program&#41; and the World Health Organization &#40;WHO&#41;"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Domingo Hernandez, Alejandra Alvarez, Ana Maria Armas, Margarita Rufino, Esteban Porrini, Armando Torres"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Domingo"
              "apellidos" => "Hernandez"
            ]
            1 => array:2 [
              "nombre" => "Alejandra"
              "apellidos" => "Alvarez"
            ]
            2 => array:2 [
              "nombre" => "Ana Maria"
              "apellidos" => "Armas"
            ]
            3 => array:2 [
              "nombre" => "Margarita"
              "apellidos" => "Rufino"
            ]
            4 => array:2 [
              "nombre" => "Esteban"
              "apellidos" => "Porrini"
            ]
            5 => array:2 [
              "nombre" => "Armando"
              "apellidos" => "Torres"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699509005138"
        "doi" => "10.3265/Nefrologia.2009.29.1.20.1.en.full.pdf"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509005138?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005135?idApp=UINPBA000064"
    "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005135/v0_201502091633/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "titulo" => "Renal length by ultrasound in Mexican adults"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "30"
        "paginaFinal" => "34"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Justo Oyuela-Carrasco, Franciso Rodr&#237;guez-Castellanos, Eric Kimura, Rosa Elena Delgado, Juan Pablo Herrera-Felix"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "Justo"
            "apellidos" => "Oyuela-Carrasco"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Franciso"
            "apellidos" => "Rodr&#237;guez-Castellanos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Eric"
            "apellidos" => "Kimura"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Rosa Elena"
            "apellidos" => "Delgado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Juan Pablo"
            "apellidos" => "Herrera-Felix"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Departamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chavez Cuidad de México, México, México, "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Longitud renal por ultrasonograf&#237;a en poblaci&#243;n mexicana adulta"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig1"
        "etiqueta" => "Fig. 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f1_p32.jpg"
            "Alto" => 312
            "Ancho" => 397
            "Tamanyo" => 12689
          ]
        ]
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">INTRODUCTION</span></p><p class="elsevierStylePara">Renal length estimation by ultrasound is an important parameter in clinical evaluation of adult patients kidney disease and healthy adult donors<span class="elsevierStyleSup">1&#44;2</span> and has replaced radiography as the common standard&#46; Ultrasound is a useful&#44; accessible&#44; non-invasive&#44; inexpensive method to reliably measure renal size&#46;<span class="elsevierStyleSup">3</span></p><p class="elsevierStylePara">Some renal diseases can change the morphological characteristics of the kidney seen by ultrasound&#46; Renal size can also be a decisive factor for performing renal biopsy or avoiding immunosuppressive therapy&#46;<span class="elsevierStyleSup">2</span> Estimating renal size by ultrasound can be done by measuring the length&#44; total volume or cortical thickness&#46; The most accurate measurement of renal size is the total renal volume&#44; which is correlated with height&#44; weight and total body area&#46; This measurement requires expensive&#44; highly complex studies with specific protocols&#44; such as axial tomography and magnetic resonance&#46; However&#44; renal length has also been shown to be a reliable parameter<span class="elsevierStyleSup">2</span> with a high level of interand intra-observer reproducibility in comparison to volumetric renal estimation&#44; which correlates appropriately with function and different anthropometric variables&#46;<span class="elsevierStyleSup">4</span></p><p class="elsevierStylePara">Renal size depends on different factors&#44; which include size&#44; body mass index and gender&#46; However&#44; race has particular connotations&#44; which directly determines all the previous variables&#46; The change in renal size can be very suggestive evidence of disease&#44; whose interpretation requires specific parameters for the population to study&#46; It is therefore necessary to have benchmark parameters in our population group&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">MATERIALS AND METHODS</span></p><p class="elsevierStylePara">Prospective observational study carried out during the period between April and June 2008&#46; An ultrasound screening was carried out on 153 healthy volunteers who complied with the following criteria for inclusion&#58; serum creatinin &#8804; 1&#46;5mg&#47;dl&#44; glycaemia &#8804; 110mg&#47;dl in patients aged over 40 years or with BMI &#62; 30kg&#47;mt<span class="elsevierStyleSup">2</span>&#44; arterial normotensive &#40;systolic blood pressure &#60; 140mmHg and diastolic blood pressure &#60; 90mmHg&#41;&#44; no existence of acute or chronic disease capable of causing damage to renal function and normal appearance of the kidneys by ultrasound &#40;thickness of renal parenchyma &#62; 1cm and corticomedullary ratio detectable by ultrasound&#46;&#41; Patients with the following conditions were excluded&#58; cysts greater than 4cm&#44; polycystic kidney disease&#44; multiple cysts &#40;&#62; 4&#41;&#44; sole kidney&#44; hydronephrosis&#44; poor ultrasound examination window &#40;automatically elevated kidney&#44; with interference in costal arches&#41;&#44; pregnancy&#44; extreme obesity&#44; renal tumours and horseshoe kidney&#46;</p><p class="elsevierStylePara">Height was measured without shoes or hat&#44; using a stadiometer&#46; The ultrasound measurement was made by a single observer&#44; using a TITAN Sonosite high resolution device&#44; with a 3&#46;5MHz convex transductor&#46; All the participants emptied their bladders prior to the examination&#44; to avoid an increase in renal length caused by oral hydration&#46;<span class="elsevierStyleSup">5</span> Renal length was measured as the longest longitudinal diameter&#44; with the patient fasting and in three positions &#40;supine&#44; supine lateral and prone&#46;&#41; Three measurements were taken for each kidney&#44; registering the longest length in absolute terms&#46;</p><p class="elsevierStylePara">The results were expressed as an average &#43; DS&#46; The averages of the different numerical variables were compared by gender using the t-Student test for independent samples&#46; An association test was performed between the different renal lengths and the anthropometric variables using the Pearson correlation coefficient&#46; Finally&#44; the total student population was divided into age groups with 10-year intervals and a comparison was LRL and RRL between the different age groups using a one-way analysis of variance&#44; followed by Bonferroni&#8217;s multiple-comparison test &#40;<span class="elsevierStyleItalic">post hoc</span>&#46;&#41; A value of p &#60; 0&#46;05 was considered statistically significant&#46; The SPSS version 15 statistical packet for Windows was used&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">RESULTS</span></p><p class="elsevierStylePara">A total of 157 subjects were included&#44; four of whom were excluded due to the presence of solid cysts over 4cm long &#40;two subjects&#41;&#44; morbid obesity &#40;one subject&#41; and one case with a very thin renal cortex &#40;&#60; 1cm&#41;&#46; Of the 153 individuals evaluated&#44; 77 were male and 76 female&#44; with an average age of 46&#46;12 &#43; 15&#46;44 years &#40;range between 20 and 79 years&#46;&#41; The average for the different anthropometric measurements in the total study population &#40;weight&#44; height and BMI&#41; was&#58; 68&#46;87 &#177; 11&#46;69kg&#44; 160 &#177; 8&#46;62cm and 26&#46;7 &#177; 3&#46;82kg&#47;mt<span class="elsevierStyleSup">2</span>&#44; respectively&#46; The left renal length in the total group was an average of 105&#46;8 &#177; 7&#46;56mm&#44; and the right renal length 104&#46;3 &#177; 6&#46;45mm &#40;p &#61; 0&#46;000&#46;&#41; With regard to the Cr S&#44; the average value for the total group 0&#46;86 &#177; 0&#46;17&#44; with a range of 0&#46;5 to 1&#46;3mg&#47;dl&#59; and specifically for the 60 to 70 years age group the average value was 0&#46;94 &#177; 0&#46;17&#44; with a range of 0&#46;63 to 1&#46;3mg&#47;dl&#46; The glomerular filtration for this age group&#44; estimated with the Cockroft-Gault formula&#44; corresponds to 66 &#177; 14&#46;8ml&#47;min&#44; with a range of 42 to 93ml&#47;min&#46;</p><p class="elsevierStylePara">When the study population was divided by gender&#44; the following data was found&#58; the average weight was 73&#46;77 &#177; 11&#46;29kg for males &#40;range of 52 to 111kg&#41; and 63&#46;9 &#177; 9&#46;90kg for women &#40;range of 43&#46;5 to 85kg&#41; &#40;p &#61; 0&#46;00&#46;&#41; The average height was 166 &#177; 6&#46;15cm for males &#40;range of 155 to 185cm&#41; and 154&#46;7 &#177; 5&#46;97cm for women &#40;range of 139 to 167cm&#41; &#40;p &#61; 0&#46;00&#46;&#41;</p><p class="elsevierStylePara">The average LRL in men was 107&#46;16 &#177; 6&#46;97mm &#40;range of 90 or 121mm&#41;&#44; and in women&#44; from 104&#46;6 &#177; 7&#46;96mm &#40;range from 88 to 122mm&#41; &#40;p &#61; 0&#46;036&#46;&#41; The average RRL in men was 105&#46;74 &#177; 5&#46;74mm &#40;range of 93 or 120mm&#41;&#44; and in women&#44; from 102&#46;99 &#177; 6&#46;85mm &#40;range from 89 to 120mm&#41; &#40;p &#61; 0&#46;008&#46;&#41;</p><p class="elsevierStylePara">When the total study population was divided up according to age groups &#40;group 1&#58; 20-29 years&#59; group 2&#58; 30-39 years&#59; group 3&#58; 40-49 years&#59; group 4&#58; 50-59 years&#59; group 5&#58; 60-69 years&#59; group 6&#58; 70-79 years&#41;&#44; and when their LRL are compared&#44; the following measurements were found by group&#58; 106 &#177; 6&#46;53mm &#40;range from 95 to 119mm&#41;&#44; 106&#46;9 &#177; 6&#46;20mm &#40;range from 93 to 119mm&#41;&#44; 107&#46;6 &#177; 8&#46;3mm &#40;range from 91 to 122mm&#41;&#44; 106 &#177; 6&#46;9mm &#40;range from 92 to 120mm&#41;&#44; 102&#46;9 &#177; 8mm &#40;range from 88 to 116mm&#41; and 99 &#177; 7&#46;92mm &#40;range from 89 to 118mm&#41; from groups 1 to 6&#44; respectively&#44; significantly different in form for 6 vs&#46; groups 2 and 3 &#40;p &#60; 0&#46;05&#41; &#40;table 1 and figure 1&#46;&#41;</p><p class="elsevierStylePara">With regard to the RRL&#44; the following measurements were observed per group&#58; 103 &#177; 6&#46;06mm &#40;range from 92 to 120mm&#41;&#44; 105 &#177; 5&#46;57mm &#40;range from 94 to 116mm&#41;&#44; 105&#46;8 &#177; 7mm &#40;range from 90 to 120mm&#41;&#44; 106 &#177; 6&#46;0mm &#40;range from 95 to 116mm&#41;&#44; 102 &#177; 6&#46;5mm &#40;range from 92 to 114mm&#41; y 100 &#177; 6&#46;93mm &#40;range from 89 to 110mm&#41; for groups 1 to 6&#44; respectively&#44; which were not significantly different &#40;p &#61; NS&#41; &#40;table 1&#46;&#41; The association test performed using the Pearson correlation coefficient showed a significant positive correlation between both renal lengths and the different anthropometric measurements &#40;weight&#44; BMI and height&#41;&#44; for the LRL &#40;r&#61;0&#46;516&#44; p&#61;0&#46;000&#59; r &#61; 0&#46;408&#59; p &#61; 0&#46;000&#59; and r &#61; 0&#46;260&#44; p &#61; 0&#46;001&#44; respectively&#41; and for the RRL &#40;r &#61; 0&#46;501&#44; p &#61; 0&#46;000&#59; r &#61; 0&#46;363&#44; p &#61; 0&#46;000&#59; and r &#61; 0&#46;289&#44; p &#61; 0&#46;000&#44; respectively&#41; &#40;table 2 and figure 2&#46;&#41;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">DISCUSSION</span></p><p class="elsevierStylePara">Renal disease can increase or decrease renal size&#44; and may or may not be accompanied by changes to the normal organ structure&#46; Ultrasound has been shown to be a diagnostic method for taking these measurements&#44; which offers the advantage of being a non-invasive&#44; innocuous method for the patient in comparison to other measurement methods such as simple radiography or intravenous urography&#44; which have also shown their effectiveness in renal size evaluation&#46;</p><p class="elsevierStylePara">Renal length and volume are important parameters in the clinical scenario&#46; Specifically&#44; renal length measurement is more valuable in adults due to its reproducibility and accuracy&#46; Because of this&#44; it is essential to know the normal limits of renal size in patients for the purposes of correctly interpreting the study&#46;</p><p class="elsevierStylePara">In this study a significant difference in weight and height was observed when gender comparisons were made &#40;p &#61; 0&#46;00&#46;&#41; At the same time&#44; gender-related differences related to the RL were confirmed&#44; showing that the length of both kidneys was significantly greater in men than in women&#46; Similar data to that shown in earlier studies has been shown&#44;<span class="elsevierStyleSup">8&#44;9</span> in contrast to the paediatric population&#44; where generally speaking no significant differences have been seen in renal length&#44; probably related to the size of the sample and the strength of each study&#46;<span class="elsevierStyleSup">10</span></p><p class="elsevierStylePara">It is of great relevance that the decrease in both renal lengths &#40;LRL&#44; RRL&#41; from 60 years&#44; which was significant from 70 years on&#44; mainly for the LRL &#40;p &#60; 0&#46;05&#41;&#44; while the renal lengths in subjects aged between 20 and 59 years remained relatively homogeneous&#46; Therefore&#44; it would appear that renal length decreases considerably with age and that the rate of decrease accelerates with age&#44; especially after 60 years&#44; but above all after 70 years&#46; Other authors have shown results&#44; showing that the length and renal volume in subjects aged between 30 to 60 years showed slight differences and a clear decrease in both parameters after 70 years&#46;<span class="elsevierStyleSup">9</span> In this context&#44; the changes in renal structure and shape that take place in human beings with age&#44; decreased renal mass and renal weight and size&#44; are well known&#46;<span class="elsevierStyleSup">11</span> Post mortem studies have shown that the weight of the kidney is between 250 and 270g in young adults&#44; which falls over the years to 200g in the ninth decade of life&#46;<span class="elsevierStyleSup">12</span> Factors such as glomerulosclerosis and tubulointerstitial fibrosis could lead to a decrease in renal size and weight&#44; as histological data reveals a decrease in the number of cortical glomerules by 30-50&#37; at the age of 70 years&#44; as well as observing a loss of glomerular lobulation&#44; increasing mesangial volume and glomerular collapse&#44; as well as intimal thickening hyalinosis of both the arteries and the arteriola&#46;<span class="elsevierStyleSup">13-15</span> The latter can be explained by a decrease in the proangiogenic vascular endothelial growth&#44; as well as an increase in the expression of the antiangiogenic factor thrombospondin 1&#44; as has been shown in elderly rats&#46; Among other factors associated as potential modulators of renal fibrosis in elderly animals&#44; angiotensin II has been mentioned&#44; which is the beta transformer growth factor &#40;TGF-&#946;&#41;&#44; changes in the expression de Nitrous Oxide &#40;NO&#41;&#44; final products of advanced glycosylation &#40;AGE&#41;&#44; oxidative stress and changes in lipids&#44; may be future targets to modulate the progression of sclerosis and the decrease in renal size&#46;<span class="elsevierStyleSup">12</span></p><p class="elsevierStylePara">The decrease in renal length at 60 years&#44; and in particular from 70 years&#44; was significant for LRL&#44; not for RRL&#44; which showed no significant difference between the age groups in our study&#44; in contrast to the results published by other authors&#46; The left kidney was significantly larger than the right&#44; which was similar to the results of the majority of studies published&#46; This difference could be explained by the fact that the liver is bigger than the spleen&#44; which means that the right kidney has less space to grow&#46; Another possible explanation is related to the shorter length of the left renal artery&#44; which increases blood flow to the left kidney&#44; with the corresponding increase with regard to the volume and size of the kidney&#46; Finally&#44; the height &#40;shorter in our population&#41; may limit the free longitudinal growth of both kidneys&#46;</p><p class="elsevierStylePara">On the other hand&#44; the two renal lengths correlate in a significantly positive manner with weight and BMI&#44; and weakly with height&#44; in contrast to other studies in adults where the strength of this association has been significantly greater with height&#46;<span class="elsevierStyleSup">8&#44;9</span> On the other hand&#44; in the paediatric population a greater association with renal length has been found with the average TFG with inulin6 and with body surface area&#46;<span class="elsevierStyleSup">16</span></p><p class="elsevierStylePara">We consider it pertinent to explore the association of renal lengths in the future&#44; or their sum &#40;total renal length&#41;&#44; with different anthropometric measurements&#44; as well as with renal function parameters&#46;</p><p class="elsevierStylePara"><span class="elsevierStyleBold">CONCLUSIONS</span></p><p class="elsevierStylePara">In conclusion&#44; LRL was significantly greater than RRL in our population&#44; and both renal lengths were greater in men than in women&#46; Renal size and height were shorter in this population in comparison with figures published in European populations&#46; A fall in the RL was observed with age&#44; especially after 60 years&#44; but significantly after the age of 70 years&#46; Both RL correlated positively with weight&#44; the BMI and height&#46;</p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;f1&#95;p32&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_f1_p32.jpg"></img></a></p><p class="elsevierStylePara">Figure 1&#46; </p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;t1&#95;p32&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_t1_p32.jpg" alt="Distribution of renal length according to age group &#40;years&#41;"></img></a></p><p class="elsevierStylePara">Table 1&#46; Distribution of renal length according to age group &#40;years&#41;</p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;f2&#95;p33&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_f2_p33.jpg"></img></a></p><p class="elsevierStylePara">Figure 2&#46; </p><p class="elsevierStylePara"><a href="grande&#47;22818078&#95;t2&#95;p33&#46;jpg" class="elsevierStyleCrossRefs"><img src="22818078_t2_p33.jpg" alt="Correlation of anthropometric measurements with renal length"></img></a></p><p class="elsevierStylePara">Table 2&#46; Correlation of anthropometric measurements with renal length</p>"
    "pdfFichero" => "P-E-S-A228-EN.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:2 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440355"
          "palabras" => array:1 [
            0 => "Longitud renal"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440357"
          "palabras" => array:1 [
            0 => "Ultrasonido renal"
          ]
        ]
      ]
      "en" => array:2 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440356"
          "palabras" => array:1 [
            0 => "Renal length"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440358"
          "palabras" => array:1 [
            0 => "Renal ultrasound"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<p class="elsevierStylePara">Introducci&#243;n&#58; la estimaci&#243;n del tama&#241;o renal por ultrasonograf&#237;a es un par&#225;metro importante en la evaluaci&#243;n cl&#237;nica y en el manejo de pacientes adultos con enfermedad renal y adultos sanos donadores&#46; El cambio en el tama&#241;o renal puede ser una evidencia muy sugerente de enfermedad&#44; por lo que su interpretaci&#243;n requiere de par&#225;metros espec&#237;ficos para la poblaci&#243;n a estudiar&#46; En el caso de Am&#233;rica Latina&#44; no se han descrito par&#225;metros normales&#46; Objetivo&#58; describir par&#225;metros normales de Longitud Renal &#40;LR&#41; por ultrasonograf&#237;a en una poblaci&#243;n mexicana adulta&#46; M&#233;todos&#58; medici&#243;n ultrasonogr&#225;fica de LR en 153 adultos sanos estratificados por edad&#46; Se investig&#243; la posible asociaci&#243;n de la LR con par&#225;metros antropom&#233;tricos&#46; Resultados&#58; se estudiaron 77 varones y 76 mujeres&#59; la edad promedio fue de 44&#44;12 &#177; 15&#44;44 a&#241;os&#46; El promedio de peso&#44; &#205;ndice de Masa Corporal &#40;IMC&#41; y talla fue de 68&#44;87 &#177; 11&#44;69 kg&#44; 26&#44;77 &#177; 3&#44;82 kg&#47;m2 y 160 &#177; 8&#44;62 cm&#44; respectivamente&#46; Al dividir a la poblaci&#243;n estudiada por g&#233;nero&#44; encontramos que la talla fue de 166 &#177; 6&#44;15 cm para varones y 154&#44;7 &#177; 5&#44;97 cm para mujeres&#44; &#40;p &#61; 0&#44;00&#41;&#46; La Longitud Renal Izquierda &#40;LRI&#41; en el grupo total fue de 105&#44;8 &#177; 7&#44;56 mm&#44; y la Longitud Renal Derecha &#40;LRD&#41;&#44; de 104&#44;3 &#177; 6&#44;45 mm &#40;p &#61; 0&#44;000&#41;&#46; La LRI en varones fue de 107&#44;16 &#177; 6&#44;97 mm&#44; y en mujeres&#44; de 104&#44;6 &#177; 7&#44;96 mm&#46; La media de la LRD en varones fue de 105&#44;74 &#177; 5&#44;74 mm y en mujeres&#44; de 102&#44;99 &#177; 6&#44;85 mm&#44; &#40;p &#61; 0&#44;008&#41;&#46; La LR disminuy&#243; con la edad&#44; y la tasa de disminuci&#243;n parece aumentar despu&#233;s de los 60 a&#241;os&#46; Las LR se correlacionaron de forma significativa y positiva con el peso&#44; el IMC y la talla&#46; Conclusiones&#58; la LR fue significativamente mayor en varones que en mujeres para ambos ri&#241;ones &#40;p &#61; 0&#44;036&#41;&#46; La LR disminuy&#243; continuamente con la edad&#44; especialmente despu&#233;s de los 60 a&#241;os y de forma significativa despu&#233;s de los 70 a&#241;os&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<p class="elsevierStylePara">Introduction&#58; Renal length estimation by ultrasound is an important parameter in clinical evaluation of kidney disease and healthy donors&#46; Changes in renal volume may be a sign of kidney disease&#46; Correct interpretation of renal length requires the knowledge of normal limits&#44; these have not been described for Latin American population&#46; Objective&#58; To describe normal renal length &#40;RL&#41; by ultrasonography in a group of Mexican adults&#46; Methods&#58; Ultrasound measure of RL in 153 healthy Mexican adults stratified by age&#46; Describe the association of RL to several anthropometric variables&#46; Results&#58; A total of 77 males and 76 females were scanner&#46; The average age for the group was 44&#46;12 &#177; 15&#46;44 years&#46; The mean weight&#44; body mass index &#40;BMI&#41; and height were 68&#46;87 &#177; 11&#46;69 Kg&#44; 26&#46;77 &#177; 3&#46;82 kg&#47;m2 and 160 &#177; 8&#46;62 cm respectively&#46; Dividing the population by gender&#44; showed a height of 166 &#177; 6&#46;15 cm for males and 154&#46;7 &#177; 5&#46;97 cm for females &#40;p &#61;0&#46;00&#41;&#46; Left renal length &#40;LRL&#41; in the whole group was 105&#46;8 &#177; 7&#46;56 mm and right renal length &#40;RRL&#41; was 104&#46;3 &#177; 6&#46;45 mm &#40;p &#61; 0&#46;000&#41;&#46; The LRL for males was 107&#46;16 &#177; 6&#46;97 mm and for females was 104&#46;6 &#177; 7&#46;96 mm&#46; The average RRL for males was 105&#46;74 &#177; 5&#46;74 mm and for females 102&#46;99 &#177; 6&#46;85 mm &#40;p &#61; 0&#46;008&#41;&#46; We noted that RL decreased with age and the rate of decline accelerates alter 60 years of age&#46; Both lengths correlated significantly and positively with weight&#44; BMI and height&#46; Conclusions&#58; The RL was significantly larger in males than in females in both kidneys &#40;p &#61; 0&#46;036&#41; in this Mexican population&#46; Renal length declines after 60 years of age and specially after 70 years&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:7 [
        "identificador" => "fig1"
        "etiqueta" => "Fig. 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f1_p32.jpg"
            "Alto" => 312
            "Ancho" => 397
            "Tamanyo" => 12689
          ]
        ]
      ]
      1 => array:8 [
        "identificador" => "fig2"
        "etiqueta" => "Tab.  1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_t1_p32.jpg"
            "Alto" => 172
            "Ancho" => 827
            "Tamanyo" => 30525
          ]
        ]
        "descripcion" => array:1 [
          "en" => "Distribution of renal length according to age group &#40;years&#41;"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig3"
        "etiqueta" => "Fig. 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_f2_p33.jpg"
            "Alto" => 277
            "Ancho" => 397
            "Tamanyo" => 16452
          ]
        ]
      ]
      3 => array:8 [
        "identificador" => "fig4"
        "etiqueta" => "Tab.  2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "copyright" => "Elsevier Espa&#241;a"
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "22818078_t2_p33.jpg"
            "Alto" => 119
            "Ancho" => 400
            "Tamanyo" => 11031
          ]
        ]
        "descripcion" => array:1 [
          "en" => "Correlation of anthropometric measurements with renal length"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:1 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "- Yong Kang K, Joon Lee Y, Chul Park S, Woo Yang C, Soo Kim Y, Sung Moom I, Bok Koh Y, Kee Bang B, Soon Choi B. A comparative study of methods of estimating kidney length in kidney transplantation donors. Nephrol Dial Transplant. 2007, 22(8): 2322-2327.2. - Ablett MJ, Coulthard A, Lee RE, et al: How reliableare ultrasound measurements of renal length inadults? Br J Radiol 1995; 68:1087- 1089.3. - GavelaT, Sánchez Bayle M, Gómez Mardones G, Gallego S, Martínez-Pérez J, Moya MT, Ecographic study of kidney size in children. Nefrologia, 2006;26 (3): 325-9.4. - Emanan SA, Nielsen MB, Pedersen JF, Intraobserver and interobserver variations in sonographic measurements of kidney size in adults volunteers. A comparison of linear measurements and volumetric estimates. Acta Radiol 1995: 36 (4) 399-401. \u{A0}5.- Kantarci F, Mihmanli I, Adaleti I, Ozer H, Gulsen F, Kadioglu A, Altug A, Uysal O: The effect of fluid on renal length measurement in adults: Journal of Clinical Ultrasound. 2006; 34 (3): 128-1336.- Adibi, Khosravi. Do kidney sizes in ultrasonography correlate to glomerular filtration rate in healthy children?. Australasian Radiology,Dec 2007; 51(6): 555-595\u{A0}7.- Van Den Noortgate N, Velghe A, Petrovic M et al. The role of ultrasonography in the assessment of renal function in the elderly. J Nephrol 2003; 16: 658-628.-Miletic D, Fuckar Z, Sustic A, Mozetic V, Stimac D,Zauhar G: Sonographic measurement of absolute and relativerenal length in adults. J Clin Ultrasound. 1998; 26:185-189.9. - Emamian SA, Nielsen MB, Pedersen JF, et al: Kidneydimensions at sonography: correlation withage, sex, and habitus in 665 adult volunteers. AJRAm J Roentgenol 1993; 160:83.10.- Ece A, Gözü A, Bükte Y, Tutanc M, Kocamaz H. The effect of malnutrition on kidney size in children. Pediatr Nephrol. 2007; 22(6): 857-6311.- Gourtsoyiannis N, Prassopoulos P, Cavouras D, Pantelidis N: The thickness of the renal parenchyma decreases with age: A CT study of 360 patients. AJR Am J Roentgenol 1990; 155:541-544.12.- Brenner and Rector's The Kidney. 8th ed. Philadelphia, Pa: Saunders; 2008. P 686\u{A0}13.-Tracy RE, Berenson G, Wattigney W, Barrett TJ: The evolution of benign arterionephrosclerosis from age 6 to 70 years. Am J Pathol 1990; 136:429-439.\u{A0}14. - Melk A, Halloran PF: Cell senescence and its implications for nephrology. J Am Soc Nephrol 2001; 12:385-393.\u{A0}15. - Hill GS, Heudes D, Bariety J: Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulation. Kidney Int 2003; 63:1027-1036.16. - Wilson BE, Davies P, Shah K, Wong W, Taylor CM. Renal length and inulin in the radiologically single kidney. Pediatr Nephrol. 2003; 18(11): 1147-51."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:1 [
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109711017025"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002900000001/v0_201502091632/X2013251409005088/v0_201502091633/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35441"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originals"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002900000001/v0_201502091632/X2013251409005088/v0_201502091633/en/P-E-S-A228-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409005088?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 10 8 18
2024 October 99 36 135
2024 September 108 37 145
2024 August 96 62 158
2024 July 95 31 126
2024 June 135 49 184
2024 May 117 41 158
2024 April 73 42 115
2024 March 72 34 106
2024 February 45 39 84
2024 January 41 27 68
2023 December 50 31 81
2023 November 82 47 129
2023 October 107 38 145
2023 September 124 40 164
2023 August 64 21 85
2023 July 83 23 106
2023 June 74 23 97
2023 May 88 31 119
2023 April 59 21 80
2023 March 50 20 70
2023 February 59 21 80
2023 January 74 32 106
2022 December 51 34 85
2022 November 76 40 116
2022 October 54 31 85
2022 September 42 38 80
2022 August 59 49 108
2022 July 48 48 96
2022 June 88 39 127
2022 May 76 42 118
2022 April 57 45 102
2022 March 67 54 121
2022 February 51 50 101
2022 January 70 30 100
2021 December 59 57 116
2021 November 74 50 124
2021 October 67 46 113
2021 September 90 59 149
2021 August 55 35 90
2021 July 67 40 107
2021 June 48 33 81
2021 May 53 40 93
2021 April 186 29 215
2021 March 134 30 164
2021 February 82 37 119
2021 January 80 25 105
2020 December 55 15 70
2020 November 48 18 66
2020 October 36 23 59
2020 September 30 18 48
2020 August 39 11 50
2020 July 53 13 66
2020 June 52 19 71
2020 May 52 28 80
2020 April 91 23 114
2020 March 101 15 116
2020 February 125 14 139
2020 January 113 27 140
2019 December 132 24 156
2019 November 107 26 133
2019 October 130 23 153
2019 September 115 23 138
2019 August 80 15 95
2019 July 96 23 119
2019 June 77 6 83
2019 May 77 12 89
2019 April 129 38 167
2019 March 85 38 123
2019 February 39 12 51
2019 January 53 25 78
2018 December 75 33 108
2018 November 80 17 97
2018 October 78 25 103
2018 September 92 18 110
2018 August 65 14 79
2018 July 68 12 80
2018 June 42 10 52
2018 May 60 18 78
2018 April 36 14 50
2018 March 42 13 55
2018 February 49 8 57
2018 January 38 9 47
2017 December 47 11 58
2017 November 36 22 58
2017 October 48 6 54
2017 September 43 38 81
2017 August 30 50 80
2017 July 58 25 83
2017 June 50 11 61
2017 May 57 12 69
2017 April 24 9 33
2017 March 20 16 36
2017 February 39 20 59
2017 January 32 16 48
2016 December 71 6 77
2016 November 79 16 95
2016 October 120 12 132
2016 September 146 15 161
2016 August 236 10 246
2016 July 169 10 179
2016 June 131 0 131
2016 May 115 0 115
2016 April 96 0 96
2016 March 75 0 75
2016 February 96 0 96
2016 January 86 0 86
2015 December 132 0 132
2015 November 79 0 79
2015 October 89 0 89
2015 September 82 0 82
2015 August 77 0 77
2015 July 74 0 74
2015 June 35 0 35
2015 May 58 0 58
2015 April 5 0 5
Show all

Follow this link to access the full text of the article

Idiomas
Nefrología (English Edition)