Statistics

 array:21 [
  "pii" => "X2013251408033037"
  "issn" => "20132514"
  "doi" => " "
  "estado" => "S300"
  "fechaPublicacion" => "2008-04-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia (English Version). 2008;28:216-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4668
    "formatos" => array:3 [
      "EPUB" => 307
      "HTML" => 3824
      "PDF" => 537
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X021169950803303X"
      "issn" => "02116995"
      "doi" => " "
      "estado" => "S300"
      "fechaPublicacion" => "2008-04-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2008;28:216-7"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 11956
        "formatos" => array:3 [
          "EPUB" => 299
          "HTML" => 10579
          "PDF" => 1078
        ]
      ]
      "es" => array:12 [
        "idiomaDefecto" => true
        "titulo" => "Hipertensión secundaria a coartación de aorta y estenosis de arteria renal en adolescente con neurofibromatosis tipo 1"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "216"
            "paginaFinal" => "217"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "High blood pressure due to aortic coarctation and renal artery stenosis in a teenager with type 1 neurofibromatosis"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig1"
            "etiqueta" => "Fig. 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "copyright" => "Elsevier España"
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "508127_fig1.jpg"
                "Alto" => 415
                "Ancho" => 512
                "Tamanyo" => 30824
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "R. Pardo, L. Somalo, Serafín Málaga Guerrero, F. Santos"
            "autores" => array:4 [
              0 => array:2 [
                "Iniciales" => "R."
                "apellidos" => "Pardo"
              ]
              1 => array:2 [
                "Iniciales" => "L."
                "apellidos" => "Somalo"
              ]
              2 => array:2 [
                "nombre" => "Serafín"
                "apellidos" => "Málaga Guerrero"
              ]
              3 => array:2 [
                "Iniciales" => "F."
                "apellidos" => "Santos"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251408033037"
          "doi" => " "
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408033037?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X021169950803303X?idApp=UINPBA000064"
      "url" => "/02116995/0000002800000002/v0_201502091346/X021169950803303X/v0_201502091346/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251408033029"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-04-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2008;28:218-21"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4117
      "formatos" => array:3 [
        "EPUB" => 281
        "HTML" => 3316
        "PDF" => 520
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "Full term pregnancy after simultaneous kidney and pancreas transplantation"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "218"
          "paginaFinal" => "221"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Embarazo a término en receptora de trasplante simultáneo de riñón y páncreas"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "P. Gutiérrez, I. Martín-Mederos, M. Coloma, L. Pérez-Tamajón, José Manuel González-Posada, A. Alarcó, A. Bravo"
          "autores" => array:7 [
            0 => array:2 [
              "Iniciales" => "P."
              "apellidos" => "Gutiérrez"
            ]
            1 => array:2 [
              "Iniciales" => "I."
              "apellidos" => "Martín-Mederos"
            ]
            2 => array:2 [
              "Iniciales" => "M."
              "apellidos" => "Coloma"
            ]
            3 => array:2 [
              "Iniciales" => "L."
              "apellidos" => "Pérez-Tamajón"
            ]
            4 => array:2 [
              "nombre" => "José Manuel"
              "apellidos" => "González-Posada"
            ]
            5 => array:2 [
              "Iniciales" => "A."
              "apellidos" => "Alarcó"
            ]
            6 => array:2 [
              "Iniciales" => "A."
              "apellidos" => "Bravo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699508033021"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508033021?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408033029?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000002/v0_201502091614/X2013251408033029/v0_201502091615/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251408033045"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-04-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2008;28:212-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4307
      "formatos" => array:3 [
        "EPUB" => 287
        "HTML" => 3469
        "PDF" => 551
      ]
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "titulo" => "Renal failure due to light chain deposition disease"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "212"
          "paginaFinal" => "215"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Insuficiencia renal por enfermedad de depósito de cadenas ligeras"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A. García Pérez, A. M. Ramos, V. Petkov, Marta Albalate, C. Caramelo, J. L. López Lorenzo, J. Aneiros, M. T. Miguel, A. Barat"
          "autores" => array:9 [
            0 => array:2 [
              "Iniciales" => "A."
              "apellidos" => "García Pérez"
            ]
            1 => array:2 [
              "Iniciales" => "A. M."
              "apellidos" => "Ramos"
            ]
            2 => array:2 [
              "Iniciales" => "V."
              "apellidos" => "Petkov"
            ]
            3 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Albalate"
            ]
            4 => array:2 [
              "Iniciales" => "C."
              "apellidos" => "Caramelo"
            ]
            5 => array:2 [
              "Iniciales" => "J. L."
              "apellidos" => "López Lorenzo"
            ]
            6 => array:2 [
              "Iniciales" => "J."
              "apellidos" => "Aneiros"
            ]
            7 => array:2 [
              "Iniciales" => "M. T."
              "apellidos" => "Miguel"
            ]
            8 => array:2 [
              "Iniciales" => "A."
              "apellidos" => "Barat"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699508033048"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508033048?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408033045?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000002/v0_201502091614/X2013251408033045/v0_201502091615/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "High blood pressure due to aortic coarctation and renal artery stenosis in a teenager with type 1 neurofibromatosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "216"
        "paginaFinal" => "217"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "R. Pardo, L. Somalo, Serafín Málaga Guerrero, F. Santos"
        "autores" => array:4 [
          0 => array:3 [
            "Iniciales" => "R."
            "apellidos" => "Pardo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:3 [
            "Iniciales" => "L."
            "apellidos" => "Somalo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:4 [
            "nombre" => "Seraf&#237;n"
            "apellidos" => "M&#225;laga Guerrero"
            "email" => array:1 [
              0 => "smalaga&#64;hca&#46;es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "Iniciales" => "F."
            "apellidos" => "Santos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Sección de Nefrología Pediátrica. Departamento de Pediatría, Hospital Universitario Central de Asturias, Asturias, Asturias, España, "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Hipertensi&#243;n secundaria a coartaci&#243;n de aorta y estenosis de arteria renal en adolescente con neurofibromatosis tipo 1"
      ]
    ]
    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">INTRODUCTION</span></p><p class="elsevierStylePara">The incidence of high blood pressure in patients with NF1 is around 1&#37;&#44;<span class="elsevierStyleSup">1</span> mainly associated to pheochromocytomas in adulthood&#46; During childhood&#44; most cases are secondary to renal artery stenosis and rarely to coarctation of the abdominal aorta<span class="elsevierStyleSup">2</span>&#46;</p><p class="elsevierStylePara">We present a 16-year old female with NF1&#44; who had been controlled since she was 3 year old because of hypertension secondary to abdominal coarctation&#44; which was angiographically confirmed&#46; She had no symptoms but the blood pressure could not be controlled with drugs &#40;atenolol&#44; hydralazine&#44; nifedipine&#41;&#46;</p><p class="elsevierStylePara">On physical exam multiple &#171;caf&#233; au lait&#187; spots could be seen&#44; as well as freckles in axillary areas&#44; with no cutaneous neurofibromas&#46; A murmur could be heard on right superior quadrant of the abdomen&#44; and peripheral pulses were palpable and symmetrical&#46; Neurological examination was normal&#46; During the follow-up&#44; the blood pressure measurements were between 150&#47;110 and 140&#47;100 mmHg&#46; These values were always over the 95th percentile for sex&#44; age and height&#46;</p><p class="elsevierStylePara">Further investigations&#58; renal function and urine catecholamines levels were within the normal range&#46; The funduscopic examination revealed grade I hypertensive retinopathy&#46; The echocardiography showed mild left ventricle hypertrophy&#46; The cranial MRI disclosed a glioma involving the optic chiasm and nerve&#46; An ambulatory blood pressure monitoring was performed&#58; During the day high blood pressure was detected with nocturnal dip&#46; On renal Doppler ultrasound the renal flow was diminished in the right kidney&#44; which suggested renal artery stenosis&#46; The abdominal angioresonance showed severe coarctation of the abdominal aorta with a lumen reduction of 85&#37; and right renal artery stenosis&#46; The same could be seen on percutaneous femoral angiography &#40;fig&#46; 1&#41;&#46;</p><p class="elsevierStylePara">With these findings surgical intervention was decided consisting on aorto-aortic bypass and right renal artery reimplantation&#46; A control angiography was performed that confirmed the reestablishment of the circulatory pattern &#40;fig&#46; 2&#41;&#46; Pharmacological therapy was required associated to oral nifedipine during four months&#46; Four years after the intervention renal function was normal&#44; Doppler ultrasounds performed during the follow-up showed preserved flows&#44; and the arterial pressure was normal&#46;</p><p class="elsevierStylePara">The frequency of high blood pressure in patients with NF1 is around 1&#37; and can be due to renal artery stenosis&#44; pheochromocytomas&#44; coarctation of the abdominal aorta&#44; or cerebral tumors&#46;<span class="elsevierStyleSup">1</span> During childhood&#44; the most frequent cause is renal artery stenosis&#44; while in adults it is pheochromocytoma&#46;<span class="elsevierStyleSup">3</span> The association between renal artery stenosis and aortic coarctation in patients with neurofibromatosis is exceptional<span class="elsevierStyleSup">4</span>&#46; In fact&#44; there are approximately ten cases reported in the literature&#46;<span class="elsevierStyleSup">5-7</span></p><p class="elsevierStylePara">In spite of the diagnostic advances &#40;ABPM&#44; renal Doppler ultrasound&#44; angio-MRI&#41; conventional angiography still is the main diagnostic investigation&#44; especially in those cases that will be susceptible to surgical therapy&#46; The management of these patients must be individualized&#44; according to the underlying condition and age&#46; The surgical treatment is successful in 80&#37; of the cases&#46; For this reason it is currently the preferred therapeutic option&#44; and also taking into account that in children the results of the angioplasty are not satisfactory&#46;<span class="elsevierStyleSup">8</span> Anyway&#44; the follow-up of the patients in the intermediate and long term is very important&#44; as we do not know the relapse rate of these lesions&#46; <br></br></p>"
    "pdfFichero" => "P-E-S-A508-EN.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:5 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec438499"
          "palabras" => array:1 [
            0 => "Estenosis de arteria renal"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec438501"
          "palabras" => array:1 [
            0 => "Enfermedad renal vascular"
          ]
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec438503"
          "palabras" => array:1 [
            0 => "Coartaci&#243;n"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec438505"
          "palabras" => array:1 [
            0 => "Hipertensi&#243;n renovascular"
          ]
        ]
        4 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec438507"
          "palabras" => array:1 [
            0 => "Neurofibromatosis"
          ]
        ]
      ]
      "en" => array:5 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec438500"
          "palabras" => array:1 [
            0 => "Renal artery stenosis"
          ]
        ]
        1 => array:3 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec438502"
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec438504"
          "palabras" => array:1 [
            0 => "Coarctation"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec438506"
          "palabras" => array:1 [
            0 => "Renovascular hypertension"
          ]
        ]
        4 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec438508"
          "palabras" => array:1 [
            0 => "Neurofibromatosis"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "La frecuencia estimada de la hipertensi&#243;n arterial en pacientes con neurofibromatosis tipo 1 &#40;NF1&#41; es de aproximadamente un 1&#37;&#44; habitualmente secundaria a feocromocitomas y estenosis de las arterias renales&#46; La coartaci&#243;n de aorta asociada en estos pacientes es una causa infrecuente de hipertensi&#243;n&#46; Presentamos el caso de una paciente con NF1 que padece hipertensi&#243;n desde los 3 a&#241;os de vida&#44; mal controlada con tratamiento farmacol&#243;gico&#46; Antecedentes familiares de NF1 &#40;madre&#41;&#46; A la exploraci&#243;n f&#237;sica presentaba m&#250;ltiples manchas caf&#233; con leche&#44; ef&#233;lides axilares y presi&#243;n arterial por encima de percentil 95 para edad y altura&#46; Las pruebas de laboratorio &#40;creatinina s&#233;rica&#44; electrolitos&#44; catecolaminas urinarias y aclaramiento de creatinina&#41; fueron normales&#46; La monitorizaci&#243;n ambulatoria de presi&#243;n arterial revel&#243; hipertensi&#243;n diurna con valores nocturnos normales&#46; La ecograf&#237;a Doppler renal mostr&#243; un patr&#243;n anormal de flujo en arteria renal derecha compatible con estenosis y la angiorresonancia magn&#233;tica&#58; coartaci&#243;n severa de aorta abdominal&#44; con oclusi&#243;n funcional de arteria mesent&#233;rica superior y estenosis moderada de arteria renal derecha con dilataci&#243;n postesten&#243;tica&#46; Ante estos hallazgos&#44; la paciente fue intervenida quir&#250;rgicamente&#44; con realizaci&#243;n de by-pass aorto-a&#243;rtico y reimplantaci&#243;n de arteria renal derecha&#46; Durante los cuatro meses siguientes a la intervenci&#243;n recibi&#243; tratamiento hipotensor con nifedipino oral que se suspendi&#243; ante la buena evoluci&#243;n cl&#237;nica&#46; Los controles peri&#243;dicos en la consulta durante los cuatro a&#241;os siguientes a la cirug&#237;a fueron satisfactorios&#44; con presi&#243;n arterial normal y funci&#243;n renal conservada&#46; Comentarios&#58; El control de la presi&#243;n arterial en pacientes con NF1 es aconsejable para detectar casos de hipertensi&#243;n arterial que&#44; en muchas ocasiones&#44; va a requerir tratamiento quir&#250;rgico&#46;"
      ]
      "en" => array:1 [
        "resumen" => "Hypertension affect about 1&#37; of patients with neurofibromatosis type 1 &#40;NF1&#41;&#46; Major causes are concomitant pheocromocytoma in adults and renovascular hypertension in children&#46; In most cases&#44; NF1 is associated with renal artery stenosis&#44; smooth cell proliferation and advential fibrosis&#46; We describe a 16 year old girl with hypertension complicating NF1 secondary to severe coarctation of abdominal aorta and tight stenosis of right renal artery&#44; a very uncommon case&#46; She was first diagnosed when she was 3-years-old and managed with antihypertensive drugs &#40;atenolol&#44; hidralazine and nifedipine&#41;&#59; she expirienced progressive uncontrollable hypertension but no symptoms&#44; thus she was admitted to repeat studies&#46; Laboratory evaluation &#40;including creatinine&#44; serum electrolites&#44; urinalysis&#44; urine catecholamines and creatinine clearance&#41; was normal Percutanaous transfemoral magnetic resonance angiography disclosed severe coarctation of abdomina aorta&#44; functional oclussion of superior mesenteric artery and tight stenosis of right renal artery with postestenotic dilatation&#46; Patient underwent surgery with aorto-aortic by-pass and right kidney artery reimplantation&#46; Periodical controls confirmed no hypertension&#44; even four years after surgery and normal flow patterns in Doppler ultrasonography&#46; Patients with NF1 must be screened for pheochromoctyoma and renovascular hypertension&#46; If hypertension appears&#44; careful management is mandatory&#44; as periodical follow-up even after surgey&#44; since the long-term recurrence rate of renovascular lessions is not well established&#46;"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliography"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Booth C, Preston R, Clark G, Reidy J. Management of renal vascular disease in neurofibromatosis type 1 and the role of percutaneus transluminal angioplasty. Nephrol Dial Trasplant 2002; 17: 1235-40."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Dillon MJ Renovascular hypertension. J Human Hypertens 1994; 8: 367-9."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Westenend PJ, Smedts F, de Jong MC, Lommers EJ, Assmann KJ. A 4- year old boy with neurofibromatosis and severe renovascular hypertension due to renal arterial dysplasia. Am J Surg Pathol 1994; 18: 512-6. <a href="http://www.ncbi.nlm.nih.gov/pubmed/8172325" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Riccardi VM Von. Recklingausen neurofibromatosis. N Eng J Med 1981; 305: 1617-27."
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Han M, Criado E. Renal artery stenosis and aneurysms associated with neurofibromatosis. J Vasc Surg 2005; 41: 539-43. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15838492" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Kurien A, John PR, Milford DV. Hypertension secondary to progressive vascular neurofibromatosis. Arch Dis Child 1997; 76: 454-5. <a href="http://www.ncbi.nlm.nih.gov/pubmed/9196366" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Criado E, Izquierdo L, Lujan S, Puras E, Espino M. Abdominal aortic coarctation, renovascular hypertension and neurofibromatosis. Ann Vasc Surg 2002; 16: 363-7. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11957015" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Fossali E, Signorini E, Intermite RC, Cassalini E, Lovaria A, Maninetti MM, Rossi LN. Renovascular disease and hypertension in children with neurofibromatosis I. Pediatr Nephrol 2000; 14: 806-10.  <a href="http://www.ncbi.nlm.nih.gov/pubmed/10955932" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002800000002/v0_201502091614/X2013251408033037/v0_201502091615/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35422"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case Reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002800000002/v0_201502091614/X2013251408033037/v0_201502091615/en/P-E-S-A508-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408033037?idApp=UINPBA000064"
]