Advanced Search
 array:25 [
  "pii" => "S2013251417301992"
  "issn" => "20132514"
  "doi" => "10.1016/j.nefroe.2017.11.015"
  "estado" => "S300"
  "fechaPublicacion" => "2018-01-01"
  "aid" => "365"
  "copyright" => "Sociedad Española de Nefrología"
  "copyrightAnyo" => "2017"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia (English Version). 2018;38:34-40"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4239
    "formatos" => array:3 [
      "EPUB" => 316
      "HTML" => 3274
      "PDF" => 649
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0211699517300711"
      "issn" => "02116995"
      "doi" => "10.1016/j.nefro.2017.03.013"
      "estado" => "S300"
      "fechaPublicacion" => "2018-01-01"
      "aid" => "365"
      "copyright" => "Sociedad Española de Nefrología"
      "documento" => "article"
      "crossmark" => 0
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2018;38:34-40"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 4663
        "formatos" => array:3 [
          "EPUB" => 260
          "HTML" => 3592
          "PDF" => 811
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "34"
            "paginaFinal" => "40"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Evaluation of the dialyser inner diameter in online haemodiafiltration"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 1310
                "Ancho" => 1625
                "Tamanyo" => 75600
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variaciones en la dosis de di&#225;lisis&#44; medidas por dialisancia i&#243;nica&#44; expresada como litros de Kt en las diferentes situaciones de estudio &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA para datos repetidos&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Francisco Maduell, Raquel Ojeda, Lara Belmar, Paula Mungu&#237;a, Cristina Sango, Ana Isabel Martinez-D&#237;az, Marta Arias-Guill&#233;n, Manel Vera, N&#233;stor Fontser&#233;, Miquel G&#243;mez, Lida Rodas, Nayra Rico"
            "autores" => array:12 [
              0 => array:2 [
                "nombre" => "Francisco"
                "apellidos" => "Maduell"
              ]
              1 => array:2 [
                "nombre" => "Raquel"
                "apellidos" => "Ojeda"
              ]
              2 => array:2 [
                "nombre" => "Lara"
                "apellidos" => "Belmar"
              ]
              3 => array:2 [
                "nombre" => "Paula"
                "apellidos" => "Mungu&#237;a"
              ]
              4 => array:2 [
                "nombre" => "Cristina"
                "apellidos" => "Sango"
              ]
              5 => array:2 [
                "nombre" => "Ana Isabel"
                "apellidos" => "Martinez-D&#237;az"
              ]
              6 => array:2 [
                "nombre" => "Marta"
                "apellidos" => "Arias-Guill&#233;n"
              ]
              7 => array:2 [
                "nombre" => "Manel"
                "apellidos" => "Vera"
              ]
              8 => array:2 [
                "nombre" => "N&#233;stor"
                "apellidos" => "Fontser&#233;"
              ]
              9 => array:2 [
                "nombre" => "Miquel"
                "apellidos" => "G&#243;mez"
              ]
              10 => array:2 [
                "nombre" => "Lida"
                "apellidos" => "Rodas"
              ]
              11 => array:2 [
                "nombre" => "Nayra"
                "apellidos" => "Rico"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2013251417301992"
          "doi" => "10.1016/j.nefroe.2017.11.015"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417301992?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517300711?idApp=UINPBA000064"
      "url" => "/02116995/0000003800000001/v1_201801090621/S0211699517300711/v1_201801090621/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2013251418300026"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2018.01.002"
    "estado" => "S300"
    "fechaPublicacion" => "2018-01-01"
    "aid" => "396"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:41-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6113
      "formatos" => array:3 [
        "EPUB" => 296
        "HTML" => 5154
        "PDF" => 663
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Correction of 25-OH-vitamin D deficiency improves control of secondary hyperparathyroidism and reduces the inflammation in stable haemodialysis patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "41"
          "paginaFinal" => "47"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "La correcci&#243;n del d&#233;ficit de 25-OH-vitamina D mejora el control del hiperparatiroidismo secundario y el estado inflamatorio de pacientes estables en hemodi&#225;lisis"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0020"
          "etiqueta" => "Fig&#46; 4"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr4.jpeg"
              "Alto" => 1362
              "Ancho" => 2669
              "Tamanyo" => 145520
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Determination of microinflammation in patients&#44; before and after treatment&#44; given as the percentage of activated monocytes &#40;CD14&#43;&#47;CD16&#43;&#41; before and after treatment &#40;A&#41; and as the levels of C-reactive protein &#40;CRP&#41; &#40;B&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Raquel Ojeda L&#243;pez, Elvira Esquivias de Motta, Andr&#233;s Carmona, Victoria Garc&#237;a Montemayor, Isabel Berdud, Alejandro Mart&#237;n Malo, Pedro Aljama Garc&#237;a"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Raquel"
              "apellidos" => "Ojeda L&#243;pez"
            ]
            1 => array:2 [
              "nombre" => "Elvira"
              "apellidos" => "Esquivias de Motta"
            ]
            2 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Carmona"
            ]
            3 => array:2 [
              "nombre" => "Victoria"
              "apellidos" => "Garc&#237;a Montemayor"
            ]
            4 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Berdud"
            ]
            5 => array:2 [
              "nombre" => "Alejandro"
              "apellidos" => "Mart&#237;n Malo"
            ]
            6 => array:2 [
              "nombre" => "Pedro"
              "apellidos" => "Aljama Garc&#237;a"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699517301315"
        "doi" => "10.1016/j.nefro.2017.05.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517301315?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251418300026?idApp=UINPBA000064"
    "url" => "/20132514/0000003800000001/v1_201802180616/S2013251418300026/v1_201802180616/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S2013251417302158"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2017.04.018"
    "estado" => "S300"
    "fechaPublicacion" => "2018-01-01"
    "aid" => "383"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "ssu"
    "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:27-33"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3003
      "formatos" => array:3 [
        "EPUB" => 269
        "HTML" => 2196
        "PDF" => 538
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Brief review</span>"
      "titulo" => "Advances in the evaluation of bone health in kidney transplant patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "27"
          "paginaFinal" => "33"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Avances en la valoraci&#243;n de la salud &#243;sea en el trasplantado renal"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1981
              "Ancho" => 2865
              "Tamanyo" => 281712
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Comparison between the different diagnostic tests to estimate bone health&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mar&#237;a Jos&#233; P&#233;rez-S&#225;ez, Daniel Prieto-Alhambra, Adolfo D&#237;ez-P&#233;rez, Julio Pascual"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mar&#237;a Jos&#233;"
              "apellidos" => "P&#233;rez-S&#225;ez"
            ]
            1 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Prieto-Alhambra"
            ]
            2 => array:2 [
              "nombre" => "Adolfo"
              "apellidos" => "D&#237;ez-P&#233;rez"
            ]
            3 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Pascual"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699517301030"
        "doi" => "10.1016/j.nefro.2017.04.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517301030?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417302158?idApp=UINPBA000064"
    "url" => "/20132514/0000003800000001/v1_201802180616/S2013251417302158/v1_201802180616/en/main.assets"
  ]
  "en" => array:21 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
    "titulo" => "Evaluation of the dialyzer inner diameter in online haemodiafiltration"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "34"
        "paginaFinal" => "40"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Francisco Maduell, Raquel Ojeda, Lara Belmar, Paula Mungu&#237;a, Cristina Sango, Ana Isabel Martinez-D&#237;az, Marta Arias-Guill&#233;n, Manel Vera, N&#233;stor Fontser&#233;, Miquel G&#243;mez, Lida Rodas, Nayra Rico"
        "autores" => array:12 [
          0 => array:4 [
            "nombre" => "Francisco"
            "apellidos" => "Maduell"
            "email" => array:1 [
              0 => "fmaduell&#64;clinic&#46;ub&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Raquel"
            "apellidos" => "Ojeda"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Lara"
            "apellidos" => "Belmar"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Paula"
            "apellidos" => "Mungu&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Cristina"
            "apellidos" => "Sango"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Ana Isabel"
            "apellidos" => "Martinez-D&#237;az"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Marta"
            "apellidos" => "Arias-Guill&#233;n"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "Manel"
            "apellidos" => "Vera"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          8 => array:3 [
            "nombre" => "N&#233;stor"
            "apellidos" => "Fontser&#233;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          9 => array:3 [
            "nombre" => "Miquel"
            "apellidos" => "G&#243;mez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          10 => array:3 [
            "nombre" => "Lida"
            "apellidos" => "Rodas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          11 => array:3 [
            "nombre" => "Nayra"
            "apellidos" => "Rico"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Hospital Cl&#237;nic&#44; Barcelona&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Bioqu&#237;mica&#44; Hospital Cl&#237;nic&#44; Barcelona&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1310
            "Ancho" => 1625
            "Tamanyo" => 79063
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variations in the dose of dialysis&#44; measured by ionic dialysance&#44; expressed as liters of Kt in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">On-line hemodiafiltration &#40;OL-HDF&#41; with a high volume of replacement combines diffusive with convective treatment&#44; allows a greater clearance of solutes of medium and high molecular weight and improves intradialysis hemodynamic tolerance&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;2</span></a> The ESHOL<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">3</span></a> study demonstrated that post-dilution OL-HDF reduces mortality from any cause with respect to hemodialysis &#40;HD&#41; in prevalent patients on HD&#46; The inclusion of the main randomized clinical trials in a pooling project with more than 2700 patients<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">4</span></a> and several meta-analysis<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">5&#44;6</span></a> has confirmed the reduction in overall and cardiovascular mortality&#46; In a post hoc analysis&#44; the 3 clinical trials that had mortality as the main variable<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#44;7&#44;8</span></a> observed an association between convective volume and survival&#46; Taking into consideration these results&#44; it has been recommended to achieve a replacement volume greater than 21<span class="elsevierStyleHsp" style=""></span>L&#47;session&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">9</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The main factors limiting the achievement of high convective volumes are blood flow &#40;Qb&#41;&#44; time and dialyzer&#46; The pharmaceutical industry has improved the dialyzers optimizing the pore size to obtain greater volumes of substitution and greater purification&#46;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">10&#44;11</span></a> However&#44; the question of the effect of inner diameter of the capillary fibers of these dialyzers is contradictory&#46; In the year 2000&#44; Ronco et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a> in an in vitro and in vivo study in HD&#44; showed that the reduction of the inner diameter was associated with an increase in proximal filtration and a distal backfiltration&#44; which improved the removal of large molecules&#44; through a greater internal convective volume&#46; They recommended reducing the inside diameter from 200<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;standard in those years&#41; to a lower one&#44; provided that an ultrapure dialysis fluid was available&#46; However&#44; with the progressive advance of OL-HDF&#44; the pharmaceutical industry offers again capillary fibers with a higher inner diameter&#44; probably to reduce the pressure of blood entering the dialyzer&#44; since&#44; in some monitors&#44; it conditions the transmembrane pressure&#46; To clarify this issue&#44; the present study was performed to determine the effect of increasing the inner diameter of the capillary fibers on convective volume and depurative capacity&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">Study performed in one single center in stable patients on OL-HDF&#46; We included 16 patients &#40;12 men and 4 women&#41; with a mean age of 64&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13 years &#40;range 42&#8211;91 years&#41; who were in the HD program for an average of 64<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>67 months &#40;interval 5&#8211;251 months&#41;&#46; The etiology of chronic renal failure was chronic glomerulonephritis &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#41; &#40;10&#46;8&#37;&#41;&#44; diabetic nephropathies &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41; &#40;8&#46;1&#37;&#41;&#44; polycystic kidney disease &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#41; &#40;5&#46;4&#37;&#41;&#44; vascular nephropathies &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#41; &#40;5&#46;4&#37;&#41;&#44; urological causes &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41; &#40;8&#46;1&#37;&#41;&#44; systemic disease &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#41; &#40;2&#46;7&#37;&#41; and unknown etiology &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#41; &#40;2&#46;7&#37;&#41;&#46; All patients were dialyzed through arteriovenous fistula except one&#44; which was dialyzed through a prosthetic fistula&#46; The anticoagulation used was heparin of low molecular weight &#40;tinzaparin&#41; in 50&#37;&#44; heparin sodium in 25&#37; of the patients and the remaining 25&#37; were dialyzed without heparin&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Each patient was analyzed in 4 sessions&#44; always mid-week&#44; in which the inner diameter of the capillary fibers of the dialyzer was changed&#58; 185<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX60 Cordiax and FX80 Cordiax&#41; vs&#46; 210<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX600 Cordiax and FX800 Cordiax&#41;&#46; The characteristics of the dialyzers are shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; The dialysis parameters were kept constant in each of the studied sessions&#58; helixone plus membrane&#59; dialysis time&#44; 293<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17<span class="elsevierStyleHsp" style=""></span>min &#40;240&#8211;300<span class="elsevierStyleHsp" style=""></span>min&#41;&#59; dialysate flow &#40;Qd&#41; 400<span class="elsevierStyleHsp" style=""></span>mL&#47;min and monitor 5008 Cordiax&#44; post-dilution OL-HDF with auto-substitution system&#46; The order of the sessions was randomized&#46; The dialysis parameters collected in each session were&#58; programmed time&#44; real duration&#44; dialyzer&#44; Qb&#44; Qd&#44; caliber of the needles&#44; Kt automatically measured by ionic dialysance&#44; recirculation index measured by the temperature module&#44; arterial pressure&#44; venous pressure&#44; transmembrane pressure&#44; initial and final hematocrit&#44; ultrafiltration&#44; volume of blood processed and substitution volume&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Laboratory measurements included the concentrations of urea &#40;60<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; creatinine &#40;113<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#946;<span class="elsevierStyleInf">2</span>-microglobulin &#40;11&#44;800<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; myoglobin &#40;17&#44;200<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; prolactin &#40;23&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin &#40;33&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein &#40;41&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41; and albumin &#40;66&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41; in serum at the beginning and at the end of each session to calculate the percentage reduction of these solutes&#46; The final concentration of &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; myoglobin&#44; prolactin&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin&#44; &#945;<span class="elsevierStyleInf">1</span>-glycoprotein and albumin were corrected for the degree of hemoconcentration and the volume of distribution &#40;approximately extracellular volume&#41; according to Bergstr&#246;m and Wehle&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">13</span></a> Urea&#44; creatinine and albumin concentrations were measured by molecular absorption spectrometry on the ADVIA 2400 analyzer &#40;Chemistry System from Siemens Healthineers&#44; Tarrytown&#44; USA&#41;&#46; &#946;<span class="elsevierStyleInf">2</span>-microglobulin and &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein were measured by immunonephelometry with the Dimension Vista analyzer &#40;Siemens Healthineers&#41; and &#945;<span class="elsevierStyleInf">1</span>-microglobulin by immunonephelometry with the BNII analyzer &#40;Siemens Healthineers&#41;&#46; Myoglobin concentrations were measured by &#8220;sandwich&#8221; enzyme immunoassays with the Dimension EXL analyzer &#40;Siemens Healthineers&#41;&#46; Prolactin concentrations were measured by &#8220;sandwich&#8221; enzyme immunoassay with the ADVIA Centaur analyzer &#40;Siemens Healthineers&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">In all cases&#44; specific reagents were used&#46; The reference values in our laboratory are 10&#8211;50<span class="elsevierStyleHsp" style=""></span>mg&#47;dL for urea&#44; 0&#46;3&#8211;1&#46;3<span class="elsevierStyleHsp" style=""></span>mg&#47;dL for creatinine&#44; 0&#46;1&#8211;2&#46;3<span class="elsevierStyleHsp" style=""></span>mg&#47;L for &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; 0&#8211;100<span class="elsevierStyleHsp" style=""></span>ng&#47;mL for myoglobin&#44; 2&#46;8&#8211;15<span class="elsevierStyleHsp" style=""></span>ng&#47;mL for prolactin&#44; 5&#8211;25<span class="elsevierStyleHsp" style=""></span>mg&#47;L for &#945;<span class="elsevierStyleInf">1</span>-microglobulin&#44; 0&#46;38&#8211;1&#46;18<span class="elsevierStyleHsp" style=""></span>g&#47;L for &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein and 34&#8211;48<span class="elsevierStyleHsp" style=""></span>g&#47;L for albumin&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Likewise&#44; a proportional part of the dialysis fluid was collected to quantify the loss of solutes and also of albumin&#46; Urea&#44; creatinine and prolactin were measured as in serum&#46; However&#44; since the concentrations of &#946;<span class="elsevierStyleInf">2</span>-microglobulin and albumin were very low&#44; it was necessary to analyze these values with the same technology&#44; but with the methods of determination used in urine samples to increase the analytical sensitivity&#46; The &#946;<span class="elsevierStyleInf">2</span>-microglobulin was measured with more sensitive method&#58; 0&#46;004625<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The results are expressed as the arithmetic mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#46; For the analysis of the statistical significance of quantitative parameters&#44; the Student t test for paired data and ANOVA for repeated data were used&#46; A <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05 was considered statistically significant&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0045" class="elsevierStylePara elsevierViewall">All dialysis sessions were performed without notable clinical incidents&#46; Clothing of the lines or dialyzed was not observed&#46; There were no differences in dialysis parameters&#58; Qb&#44; total blood processed according to the monitor&#44; Qd&#44; real duration of sessions&#44; initial weight&#44; final weight&#44; weight gain&#44; measurements by the dialysis monitor of the initial and final hematocrit&#44; size of the needles&#44; recirculation of the vascular access&#44; arterial pressure&#44; venous pressure or transmembrane pressure &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">The increase in inner diameter in the 2 series of comparisons did not show an increase in the replacement volume &#40;29&#46;61<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33&#46;5 with FX60 Cordiax vs&#46; 29&#46;07<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33&#46;8<span class="elsevierStyleHsp" style=""></span>L&#47;session with FX600 Cordiax and 30&#46;99<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5 with FX80 Cordiax vs&#46; 30&#46;83<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1<span class="elsevierStyleHsp" style=""></span>L&#47;session with FX800 Cordiax&#41;&#59; and&#44; as expected&#44; the total convective volume was not changed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">The difference in the inner diameter of the dialysis fibers did not produce significant effect in the dialysis dose&#44; expressed as Kt &#40;71&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;7 with FX60 Cordiax vs&#46; 73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;9<span class="elsevierStyleHsp" style=""></span>L with FX600 Cordiax and 72&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>70 with FX80 Cordiax vs&#46; 74&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;7<span class="elsevierStyleHsp" style=""></span>L with FX800 Cordiax&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; nor as the percentage of urea reduction &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">The percent reduction of the rest of the solutes &#40;creatinine&#44; &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; myoglobin&#44; prolactin&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin and &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein&#41; is shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46; Neither&#44; the inner diameter of the fibers nor the 2 types of dialyzers being compared produces a significant difference in the percent reduction of solutes&#46; No significant differences were observed in the albumin eliminated through the dialysate in any of the 2 comparison series&#58; 2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;8<span class="elsevierStyleHsp" style=""></span>g for FX60 Cordiax vs&#46; 1&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX600 Cordiax and 3&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX80 Cordiax vs&#46; 3&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX800 Cordiax&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0065" class="elsevierStylePara elsevierViewall">The present study shows that&#44; in post-dilution OL-HDF&#44; the comparison of 2 series of dialyzers with inner capillary fiber diameters of 185 and 210<span class="elsevierStyleHsp" style=""></span>&#956;m showed no differences on convective volume and depurative efficacy&#46; After reviewing the literature&#44; this study represents the first study in OL-HDF in which the inner diameter is compared without changing the rest of the dialysis parameters&#46; The convective volume reached&#44; which varied between 29 and 31<span class="elsevierStyleHsp" style=""></span>L&#47;session&#44; was adequate&#44; although no statistically significant differences were observed in any of the 2 standards compared&#46; In terms of efficacy&#44; no significant differences were observed in the reduction of solutes of small and high molecular weight&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">The effectiveness of HD treatment is measured in terms of survival&#44; morbidity and quality of life obtained during both the dialysis session and the interdialysis period&#46; OL-HDF combines diffusive transport and allows a considerable increase in convective transport&#44;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">14</span></a> with a greater clearance of medium and high molecular weight toxins&#46;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">15&#44;16</span></a> OL-HDF is a safe technique that improves intradialysis hemodynamic tolerance<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;3</span></a> contributing&#44; among others&#44; to the correction of anemia&#44; the chronic inflammation&#44; amyloidosis&#44; hyperparathyroidism&#44; oxidative stress and the lipid profile&#44;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">17&#8211;19</span></a> and increases survival<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#8211;6</span></a> and quality of life&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">4&#44;20</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">During the last few years&#44; new dialyzers have been developed with greater surface area&#44; better geometric arrangement of capillary fibers&#44; variation of wall thickness&#44; larger pore size&#44; in order to achieve greater removal of both small and medium-large molecules&#46; The ideal hemodialyzer should achieve the following characteristics&#58; high clearance of small molecules&#59; high sieving coefficient for &#946;<span class="elsevierStyleInf">2</span>-microglobulin and myoglobin&#59; low sieving coefficient for albumin&#59; low transmembrane pressures that do not limit the infusion flow&#59; great power to trap endotoxins and a good price&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">21</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">The convective capacity of the dialyzers follows the Hagen&#8211;Poiseuille law&#44; &#916;p&#8201;&#61;&#8201;Qb&#215;8&#951;l&#47;&#960;r4&#44; the drop of pressure inside the dialyzer fiber is directly proportional to the Qb&#44; the length<span class="elsevierStyleSup">l</span> and the blood viscosity and inversely proportional to the inner diameter&#46; A pressure drop inside the fiber will increase the pressure gradient between the blood compartment and the dialysis compartment&#44; leading to greater convective transport&#46; Taking into account that&#44; a minimum reduction in the diameter of the capillary fiber has a great impact on the pressure drop inside the capillary fiber that will increase the pressure gradient between the blood and the dialysis fluid along the entire length of the fiber&#44; with improvement of both diffusion and convection&#46; In terms of efficacy&#44; while the increase in diffusion hardly implies variation in the clearance of small molecules&#44; a greater convective transport causes a greater clearance of f high molecular weight molecules&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In a previous study<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">22</span></a> it was shown that the increase in Qb is probably the best method to reach the highest convective volume&#46; For every 50<span class="elsevierStyleHsp" style=""></span>mL&#47;min of Qb increase&#44; the convective volume increases more than half a liter per hour&#46; The Qb increases the removal capacity of small molecules and favors that of &#946;<span class="elsevierStyleInf">2</span>-microglobulin and myoglobin&#46; In another study<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">23</span></a> the effect of increasing the dialyzer surface was evaluated&#44; and it was concluded that the increase in the dialyzer surface caused a small increase in the convective volume without evidencing an improvement in the removal capacity&#44; especially if the ultrafiltration coefficient was higher at 45<span class="elsevierStyleHsp" style=""></span>mL&#47;h&#47;mmHg&#46; In the present study&#44; we did not observe significant variations of convective volume in any of the 2-series compared&#46; Unlike the previous study&#44; in our study&#44; in addition to an increase in the inner diameter of the capillary fiber from 185<span class="elsevierStyleHsp" style=""></span>&#956;m to 210<span class="elsevierStyleHsp" style=""></span>&#956;m&#44; there was a small increase of 0&#46;2<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> in the surface of the dialyzer &#40;1&#46;4<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 60 vs&#46; 1&#46;6<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 600 and 1&#46;8<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 80 vs&#46; 2&#46;0<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 800&#41;&#46; Therefore&#44; the non-variation observed in the convective volume may be the result of the opposite variations of simultaneous increase in area and diameter that can compensate for each other&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">The publications on the effects of the variation of the inner diameter of the capillary fibers in relation to the convective volume and the removal capacity of the dialyzers are limited&#46; Dellanna et al&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">24</span></a> tested in 10 high-flow HD patients 3 types of polysulfone dialyzers with identical number and length of fibers&#44; with inner diameters of 175&#44; 200 and 250<span class="elsevierStyleHsp" style=""></span>&#956;m&#44; surfaces of 0&#46;55&#44; 0&#46;65 and 0&#46;79<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> respectively&#44; and sieving coefficients for &#946;<span class="elsevierStyleInf">2</span>-microglobulin 0&#46;82&#44; 0&#46;79 and 0&#46;71&#44; respectively&#46; With Qb 250 and Qd 500<span class="elsevierStyleHsp" style=""></span>mL&#47;min they hardly observe any variation in the clearance of small molecules such as urea or creatinine&#46; By contrast&#44; the dialyzer with the smallest diameter &#40;175<span class="elsevierStyleHsp" style=""></span>&#956;m&#41;&#44; despite having the smallest surface&#44; showed a clearance of &#946;<span class="elsevierStyleInf">2</span>-microglobulin twice that of the dialyzer of 200<span class="elsevierStyleHsp" style=""></span>&#956;m and almost 5&#46;6 times higher than that of 250<span class="elsevierStyleHsp" style=""></span>&#956;m&#46; Ronco et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a> also in HD&#44; compared in vitro and in vivo 2 types of high flow dialyzers with hollow fiber of polysulfone&#44; of 0&#46;7<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> of surface&#44; the standard with a diameter of 200<span class="elsevierStyleHsp" style=""></span>&#956;m and another modified to an inner diameter of 175<span class="elsevierStyleHsp" style=""></span>&#956;m&#46; With dialysis parameters of Qb 300 and Qd 500<span class="elsevierStyleHsp" style=""></span>mL&#47;min in vitro&#44; it was observed an increase in internal filtration and backfiltration from 23&#46;1<span class="elsevierStyleHsp" style=""></span>mL&#47;min in the fibers of 200<span class="elsevierStyleHsp" style=""></span>&#956;m diameter to 48&#46;2<span class="elsevierStyleHsp" style=""></span>mL&#47;min in the 175<span class="elsevierStyleHsp" style=""></span>&#956;m dialyzer&#46; The in vivo studies showed that the reduction in inner diameter produced an increase of 30&#37; in the clearance of intermediate solutes such as vitamin B12 or inulin&#46; Similar results were obtained by Mineshima et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a> In an analytical-experimental study they analyzed the effects of the inner diameter of the capillary fibers on the internal filtration and the efficiency in the elimination of solutes in HD&#46; They evaluated 5 dialyzers of the same surface &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span>&#41; and inner diameters of 150&#44; 175 and 3 sessions with 200<span class="elsevierStyleHsp" style=""></span>&#956;m varying the number and length of the capillary fibers&#46; They observed that a decrease in the inner diameter of the capillary fibers increased internal filtration and increased the clearance of myoglobin&#46; In this same study they show that an excessive reduction of the inner diameter may increase the risk of hemolysis and transfer of biological contaminants&#44; so they proposed that the reduction of the inner diameter should not produce an internal pressure drop superior to 150<span class="elsevierStyleHsp" style=""></span>mmHg&#44; for the patient&#39;s own safety&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">We have not found in the literature comparative studies of the inner diameter in OL-HDF&#46; In a study that analyzed the factors associated with the achievement a greater convective volume&#44; Marcelli et al&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">26</span></a> observed a convective volume of 25&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1<span class="elsevierStyleHsp" style=""></span>L in 325 patients with FX60 as compared to 27&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6<span class="elsevierStyleHsp" style=""></span>L in 2572 patients with FX600&#46; However&#44; these 2&#46;2<span class="elsevierStyleHsp" style=""></span>L of difference cannot be attributed to the change in inner diameter but to the increase in Qb &#40;352<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>54 vs&#46; 361<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>70<span class="elsevierStyleHsp" style=""></span>mL&#47;min&#41; and to the duration of treatment &#40;241<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11 vs&#46; 255<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>19<span class="elsevierStyleHsp" style=""></span>min&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">We conclude that the increase of the inner diameter of the capillary fibers in OL-HDF has not produced a greater efficiency in the convective volume nor in the depurative capacity&#46; Therefore&#44; the inner diameter in dialyzers with high ultrafiltration coefficient does not seem to be a limiting factor in convective volume&#44; as it is the blood flow or dialysis time&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflicts of interest</span><p id="par0105" class="elsevierStylePara elsevierViewall">The authors declare to have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres985571"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Material and methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusion"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec953223"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres985572"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Introducci&#243;n"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Material y m&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusi&#243;n"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec953224"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflicts of interest"
        ]
        9 => array:2 [
          "identificador" => "xack334117"
          "titulo" => "Acknowledgements"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-02-08"
    "fechaAceptado" => "2017-03-16"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec953223"
          "palabras" => array:4 [
            0 => "Dialyzer"
            1 => "Inner diameter"
            2 => "Online haemodiafiltration"
            3 => "Convective volume"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec953224"
          "palabras" => array:4 [
            0 => "Dializador"
            1 => "Di&#225;metro interno"
            2 => "Hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
            3 => "Volumen convectivo"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Online haemodiafiltration &#40;OL-HDF&#41; has been associated with increased survival&#46; To date&#44; the influence of the inner diameter of the hollow fibers of the dialyzer on convective volume has not been well established&#46; The objective of the study was to evaluate the effect of increasing the inner diameter of the dialyzer on the convective volume and removal capacity&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We included 16 patients in postdilutional OL-HDF&#46; Each patient was analyzed in 4 sessions in which the inner diameter varied&#59; 185<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX60 Cordiax and FX80 Cordiax&#41; vs&#46; 210<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX600 Cordiax and FX800 Cordiax&#41;&#46; Different solutes were measured at the beginning and end of each dialysis session&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No differences in the convective volume were found with an increased inner diameter&#58; 32&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;1 vs&#46; 31&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;6<span class="elsevierStyleHsp" style=""></span>L&#47;session &#40;FX60 vs&#46; FX600&#41; and 33&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3 vs&#46; 33&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8<span class="elsevierStyleHsp" style=""></span>L&#47;session &#40;FX80 vs&#46; FX800&#41;&#46; The reduction ratios also did not differ&#58; urea 83&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5 vs&#46; 84&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;4 for FX60 and FX600&#44; and 82&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1 vs&#46; 83&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8 for FX80 vs&#46; FX800&#59; creatinine similar 78&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6 vs&#46; 77&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6 and 77&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4 vs&#46; 78&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&#59; &#946;<span class="elsevierStyleInf">2</span>-microglobulin 82&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3 vs&#46; 82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;2&#44; and 82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;7 vs&#46; 84&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&#59; myoglobin 71&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 70&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9 and 72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11 vs&#46; 75&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#59; prolactin 70&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9 vs&#46; 68&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44; and 72&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&#59; and &#945;<span class="elsevierStyleInf">1</span>-microglobulin 22&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 21&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#44; and 26&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12 vs&#46; 28&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44; respectively&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The increase in the inner diameter of the hollow fibers did not result in improved convective volume and removal capacity&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusion"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Se ha asociado la hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span> &#40;HDF-OL&#41; a un aumento de la supervivencia&#46; Hasta el momento no est&#225; bien establecida la influencia del di&#225;metro interno de las fibras capilares del dializador sobre la capacidad convectiva&#46; El objetivo del estudio fue valorar el efecto del aumento del di&#225;metro interno del dializador sobre el volumen convectivo y la capacidad depurativa&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Material y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 16 pacientes en HDF-OL posdilucional con reposici&#243;n autom&#225;tica&#46; Cada paciente recibi&#243; 4 sesiones&#44; en las que se vari&#243; el di&#225;metro interno&#44; 185 &#956;m &#40;FX60 Cordiax y FX80 Cordiax&#41; versus 210 &#956;m &#40;FX600 Cordiax y FX800 Cordiax&#41;&#46; En cada sesi&#243;n se determinaron diferentes solutos al inicio y al final de la di&#225;lisis&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">El incremento de di&#225;metro interno entre FX60 vs&#46; FX600 y FX80 vs&#46; FX800 no reflej&#243; diferencias en el volumen convectivo&#58; 32&#44;3 &#177; 3&#44;1 vs&#46; 31&#44;8 &#177; 3&#44;6 y 33&#44;7 &#177; 4&#44;3 vs&#46; 33&#44;5 &#177; 3&#44;8 L&#47;sesi&#243;n&#44; respectivamente&#46; Los porcentajes de reducci&#243;n tampoco mostraron diferencias&#58; urea 83&#44;7 &#177; 4&#44;5 vs&#46; 84&#44;1 &#177; 3&#44;4 para FX60 y FX600 y 82&#44;7 &#177; 4&#44;1 vs&#46; 83&#44;6 &#177; 3&#44;8 para FX80 vs&#46; FX800&#59; creatinina similar 78&#44;2 &#177; 5&#44;6 vs&#46; 77&#44;8 &#177; 4&#44;6 y 77&#44;1 &#177; 5&#44;4 vs&#46; 78&#44;1 &#177; 4&#44;9&#59; &#946;<span class="elsevierStyleInf">2</span>-microglobulina 82&#44;2 &#177; 4&#44;3 vs&#46; 82&#44;9 &#177; 4&#44;2 y 82&#44;9 &#177; 4&#44;7 vs&#46; 84&#44;0 &#177; 3&#44;8&#59; mioglobina 71&#44;0 &#177; 10&#44; vs&#46; 70&#44;2 &#177; 9 y 72&#44;8 &#177; 11 vs&#46; 75&#44;0 &#177; 10&#59; prolactina 70&#44;4 &#177; 9 vs&#46; 68&#44;1 &#177; 9 y 72&#44;2 &#177; 10 vs&#46; 73&#44;4 &#177; 8&#44;2&#59; y &#945;<span class="elsevierStyleInf">1</span>-microglobulina 22&#44;9 &#177; 10 vs&#46; 21&#44;6 &#177; 10 y 26&#44;5 &#177; 12 vs&#46; 28&#44;8 &#177; 11&#44; respectivamente&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusi&#243;n</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El incremento del di&#225;metro interno de las fibras capilares no ha significado una mayor eficacia en el volumen convectivo ni en la capacidad depurativa&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introducci&#243;n"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Material y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusi&#243;n"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Maduell F&#44; Ojeda R&#44; Belmar L&#44; Mungu&#237;a P&#44; Sango C&#44; Martinez-D&#237;az AI&#44; et al&#46; Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>&#46; Nefrologia&#46; 2018&#59;38&#58;34&#8211;40&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1182
            "Ancho" => 1617
            "Tamanyo" => 75823
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Variations in convective volume during on line hemodiafiltration in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1310
            "Ancho" => 1625
            "Tamanyo" => 79063
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variations in the dose of dialysis&#44; measured by ionic dialysance&#44; expressed as liters of Kt in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">KUF&#58; ultrafiltration coefficient&#59; KoA&#58; mass transfer coefficient&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Membrane<br>Surface &#40;m<span class="elsevierStyleSup">2</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wall thickness &#40;&#956;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Inner diameter &#40;&#956;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">210&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">210&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KoA urea &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1164&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1148&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1429&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1365&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KUF &#40;mL&#47;h&#47;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KUF &#40;mL&#47;h&#47;mmHg&#47;m<span class="elsevierStyleSup">2</span>&#41;<br>Sterilization&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">33&#46;6<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&#46;8<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#46;6<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31&#46;0<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sieving coefficient &#946;<span class="elsevierStyleInf">2</span>-microglobulin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sieving coefficient myoglobin<br>Sieving coefficient albumin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672082.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Characteristics of the dialyzers&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">NS&#58; no significant&#59; Qb&#58; blood flow&#59; Qd&#58; dialysate flow&#59; Td&#58; duration of dialysis&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Qd &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Qb &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total blood processed &#40;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">128&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Needles&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Recirculation &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Td &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">283&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">283&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">282&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">282&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Initial weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Final weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">69&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">69&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Weight gain &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Initial hematocrit &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Final hematocrit &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Arterial pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;233<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;232<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;234<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;228<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Venous pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">234<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">235<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">223<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">226<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Transmembrane pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">183<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">192<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">191<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672081.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Comparison of dialysis parameters during the 4 different sessions&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Urea &#40;60<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Creatinine &#40;113<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">78&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">78&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#946;<span class="elsevierStyleInf">2</span>-microglobulin &#40;11&#46;818<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Myoglobin &#40;17&#44;200<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">71&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Prolactin &#40;23&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#945;<span class="elsevierStyleInf">1</span>-microglobulin &#40;33&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#945;<span class="elsevierStyleInf">1</span>-acid glicoprotein &#40;41&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Albumin &#40;66&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Loss of albumin in dialysate &#40;g&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672080.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Percent of solute reduction during hemodialysis&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemofiltration and hemodiafiltration reduce intradialytic hypotension in ESRD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Locatelli"
                            1 => "P&#46; Altieri"
                            2 => "S&#46; Andrulli"
                            3 => "P&#46; Bolasco"
                            4 => "G&#46; Sau"
                            5 => "L&#46;A&#46; Pedrini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2010030280"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "1798"
                        "paginaFinal" => "1807"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20813866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of high efficiency post-dilution on-line hemodiafiltration or conventional hemodialysis on residual renal function and left ventricular hypertrophy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Schiffl"
                            1 => "S&#46;M&#46; Lang"
                            2 => "R&#46; Fischer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11255-012-0336-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int Urol Nephrol"
                        "fecha" => "2013"
                        "volumen" => "45"
                        "paginaInicial" => "1389"
                        "paginaFinal" => "1396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23225079"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "ESHOL Study Group"
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "F&#46; Moreso"
                            2 => "M&#46; Pons"
                            3 => "R&#46; Ramos"
                            4 => "J&#46; Mora-Maci&#224;"
                            5 => "J&#46; Carreras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2012080875"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2013"
                        "volumen" => "24"
                        "paginaInicial" => "487"
                        "paginaFinal" => "497"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23411788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "HDF Pooling Project Investigators&#46; Sanne NDT&#46; Haemodiafiltration and mortality in end-stage kidney disease patients&#58; a pooled individual participant data analysis from four randomized controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;A&#46; Peters"
                            1 => "M&#46;L&#46; Bots"
                            2 => "B&#46; Canaud"
                            3 => "A&#46; Davenport"
                            4 => "M&#46;P&#46; Grooteman"
                            5 => "F&#46; Kircelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "2016"
                        "volumen" => "31"
                        "paginaInicial" => "978"
                        "paginaFinal" => "984"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical evidence on hemodiafiltration&#58; a systematic review and a meta-analysis"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "EUDIAL Group"
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46;M&#46; Mostovaya"
                            1 => "P&#46;J&#46; Blankestijn"
                            2 => "M&#46;L&#46; Bots"
                            3 => "A&#46; Covic"
                            4 => "A&#46; Davenport"
                            5 => "M&#46; Grooteman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Dial"
                        "fecha" => "2014"
                        "volumen" => "27"
                        "paginaInicial" => "119"
                        "paginaFinal" => "127"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24738146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Convective versus diffusive dialysis therapies for chronic kidney failure&#58; an updated systematic review of randomized controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Nistor"
                            1 => "S&#46;C&#46; Palmer"
                            2 => "J&#46;C&#46; Craig"
                            3 => "V&#46; Saglimbene"
                            4 => "M&#46; Vecchio"
                            5 => "A&#46; Covic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/j.ajkd.2013.12.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
                        "fecha" => "2014"
                        "volumen" => "63"
                        "paginaInicial" => "954"
                        "paginaFinal" => "967"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24434188"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of online hemodiafiltration on all-cause mortality and cardiovascular outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;P&#46; Grooteman"
                            1 => "M&#46;A&#46; van den Dorpel"
                            2 => "M&#46;L&#46; Bots"
                            3 => "E&#46;L&#46; Penne"
                            4 => "N&#46;C&#46; van der Weerd"
                            5 => "A&#46;H&#46; Mazairac"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2011121140"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "1087"
                        "paginaFinal" => "1096"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22539829"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022347603005808"
                          "estado" => "S300"
                          "issn" => "00223476"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mortality and cardiovascular events in online haemodiafiltration &#40;OL-HDF&#41; compared with high-flux dialysis&#58; results from the Turkish OL-HDF Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Ok"
                            1 => "G&#46; Asci"
                            2 => "H&#46; Toz"
                            3 => "E&#46;S&#46; Ok"
                            4 => "F&#46; Kircelli"
                            5 => "M&#46; Yilmaz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "2013"
                        "volumen" => "28"
                        "paginaInicial" => "192"
                        "paginaFinal" => "202"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emerging clinical evidence on online hemodiafiltration&#58; does volume of ultrafiltration matter&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46; Canaud"
                            1 => "S&#46;K&#46; Bowry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346371"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "paginaInicial" => "55"
                        "paginaFinal" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23466380"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Elimination of large uremic toxins by a dialyzer specifically designed for high-volume convective therapies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "M&#46; Arias-Guillen"
                            2 => "N&#46; Fontser&#233;"
                            3 => "R&#46; Ojeda"
                            4 => "N&#46; Rico"
                            5 => "M&#46; Vera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000358214"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2014"
                        "volumen" => "37"
                        "paginaInicial" => "125"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24662288"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experimental evaluation of flow and dialysis performance of hollow-fiber dialyzers with different packing densities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Hirano"
                            1 => "S&#46; Kida"
                            2 => "K&#46; Yamamoto"
                            3 => "K&#46; Sakai"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10047-011-0620-6"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Artif Organs"
                        "fecha" => "2012"
                        "volumen" => "15"
                        "paginaInicial" => "168"
                        "paginaFinal" => "175"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22116168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of a reduced inner diameter of hollow fibers in hemodialyzers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Ronco"
                            1 => "A&#46; Brendolan"
                            2 => "A&#46; Lupi"
                            3 => "G&#46; Metry"
                            4 => "N&#46;W&#46; Levin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1755.2000.00230.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2000"
                        "volumen" => "58"
                        "paginaInicial" => "809"
                        "paginaFinal" => "817"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10916106"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "No change in corrected &#946;<span class="elsevierStyleInf">2</span>-microglobulin concentration after cuprophane hemodialysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Bergstr&#246;m"
                            1 => "B&#46; Wehle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1987"
                        "volumen" => "1"
                        "paginaInicial" => "628"
                        "paginaFinal" => "629"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2894556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The importance of convective transport"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Locatelli"
                            1 => "C&#46; Manzoni"
                            2 => "S&#46; Di Filippo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Kidney Int Suppl"
                        "fecha" => "2002"
                        "volumen" => "80"
                        "paginaInicial" => "115"
                        "paginaFinal" => "120"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of high-flux hemodialysis on clinical outcomes&#58; results of the HEMO study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;K&#46; Cheung"
                            1 => "N&#46;W&#46; Levin"
                            2 => "T&#46; Greene"
                            3 => "L&#46; Agodoa"
                            4 => "J&#46; Bailey"
                            5 => "G&#46; Beck"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2003"
                        "volumen" => "14"
                        "paginaInicial" => "3251"
                        "paginaFinal" => "3263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14638924"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteocalcin and myoglobin removal in on-line hemodiafiltration versus low and high-flux hemodialysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "V&#46; Navarro"
                            2 => "M&#46;C&#46; Cruz"
                            3 => "E&#46; Torregrosa"
                            4 => "D&#46; Garcia"
                            5 => "V&#46; Simon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
                        "fecha" => "2002"
                        "volumen" => "40"
                        "paginaInicial" => "582"
                        "paginaFinal" => "589"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12200811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Change from conventional haemodiafiltration to on-line haemodiafiltration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "C&#46; del Pozo"
                            2 => "H&#46; Garcia"
                            3 => "L&#46; Sanchez"
                            4 => "J&#46; Hdez-Jaras"
                            5 => "M&#46;D&#46; Albero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "1999"
                        "volumen" => "14"
                        "paginaInicial" => "1202"
                        "paginaFinal" => "1207"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Online haemodiafiltration versus haemodialysis&#58; stable haematocrit with less erythropoietin and improvement of other relevant blood parameters"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46; Vaslaki"
                            1 => "L&#46; Major"
                            2 => "K&#46; Berta"
                            3 => "A&#46; Karatson"
                            4 => "M&#46; Misz"
                            5 => "F&#46; Pethoe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000090117"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2006"
                        "volumen" => "24"
                        "paginaInicial" => "163"
                        "paginaFinal" => "173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16352871"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Online haemodiafiltration&#58; effective removal of high molecular weight toxins and improvement in clinical manifestations of chronic haemodialysis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;T&#46; Kim"
                            1 => "C&#46; Yamamoto"
                            2 => "H&#46; Asabe"
                            3 => "T&#46; Sato"
                            4 => "T&#46; Takamiya"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nephrology &#40;Carlton&#41;"
                        "fecha" => "1996"
                        "volumen" => "2"
                        "numero" => "Suppl&#46; 1"
                        "paginaInicial" => "S183"
                        "paginaFinal" => "S186"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Can dialysis modality influence quality of life in chronic hemodialysis patients&#63; Low-flux hemodialysis versus high-flux hemodiafiltration&#58; a cross-over study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Kantartzi"
                            1 => "S&#46; Panagoutsos"
                            2 => "E&#46; Mourvati"
                            3 => "A&#46; Roumeliotis"
                            4 => "K&#46; Leivaditis"
                            5 => "V&#46; Devetzis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/0886022X.2012.743858"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ren Fail"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "paginaInicial" => "216"
                        "paginaFinal" => "221"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23176401"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparaci&#243;n de dializadores en hemodiafiltraci&#243;n en l&#237;nea"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "F&#46; Maduell"
                            1 => "V&#46; Navarro"
                            2 => "J&#46; Hern&#225;ndez-Jaras"
                            3 => "C&#46; Calvo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2000"
                        "volumen" => "20"
                        "paginaInicial" => "269"
                        "paginaFinal" => "276"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10917004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemodiafiltraci&#243;n on-line con autosustituci&#243;n&#58; valoraci&#243;n de los cambios del flujo de sangre sobre el volumen convectivo y eficacia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "R&#46; Ojeda"
                            2 => "L&#46; Rodas"
                            3 => "N&#46; Rico"
                            4 => "N&#46; Fontser&#233;"
                            5 => "M&#46; Arias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3265/Nefrologia.pre2014.Sep.12726"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2015"
                        "volumen" => "35"
                        "paginaInicial" => "50"
                        "paginaFinal" => "57"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25611833"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Valoraci&#243;n de la superficie del dializador en la hemodiafiltraci&#243;n on-line&#46; Elecci&#243;n objetiva de la superficie del dializador"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "R&#46; Ojeda"
                            2 => "M&#46; Arias-Guill&#233;n"
                            3 => "G&#46; Bazan"
                            4 => "M&#46; Vera"
                            5 => "N&#46; Fontser&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nefro.2015.05.003"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2015"
                        "volumen" => "35"
                        "paginaInicial" => "280"
                        "paginaFinal" => "286"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26299171"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Internal filtration &#8211; advantage in haemodialysis&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Dellanna"
                            1 => "A&#46; Wuepper"
                            2 => "C&#46;A&#46; Baldamus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "1996"
                        "volumen" => "11"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "83"
                        "paginaFinal" => "86"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of internal filtration on the solute removal efficiency of a dialyzer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Mineshima"
                            1 => "I&#46; Ishimori"
                            2 => "K&#46; Ishida"
                            3 => "T&#46; Hoshino"
                            4 => "I&#46; Kaneko"
                            5 => "Y&#46; Sato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "ASAIO J"
                        "fecha" => "2000"
                        "volumen" => "46"
                        "paginaInicial" => "456"
                        "paginaFinal" => "460"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10926146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Modificable factors associated with achievement of high-volume post-dilution hemodiafiltration&#58; results of an international study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Marcelli"
                            1 => "P&#46; Kopperschmidt"
                            2 => "I&#46; Bayh"
                            3 => "T&#46; Jirka"
                            4 => "J&#46;I&#46; Merello"
                            5 => "P&#46; Ponce"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5301/ijao.5000414"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Artif Organs"
                        "fecha" => "2015"
                        "volumen" => "38"
                        "paginaInicial" => "244"
                        "paginaFinal" => "250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26080930"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack334117"
        "titulo" => "Acknowledgements"
        "texto" => "<p id="par0110" class="elsevierStylePara elsevierViewall">We would like to express our gratitude to all the patients who have participated&#44; as well as to all the staff of the Dialysis Section of the Hospital Cl&#237;nic of Barcelona for their collaboration and enthusiasm in this study&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003800000001/v1_201802180616/S2013251417301992/v1_201802180616/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "42660"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003800000001/v1_201802180616/S2013251417301992/v1_201802180616/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417301992?idApp=UINPBA000064"
]
Share
Current Issue
Journal Information
Back to article

Statistics

Follow this link to access the full text of the article

Original article
Evaluation of the dialyzer inner diameter in online haemodiafiltration
Valoración del diámetro interno del dializador en hemodiafiltración on-line
Francisco Maduella,
Corresponding author
fmaduell@clinic.ub.es

Corresponding author.
, Raquel Ojedaa, Lara Belmara, Paula Munguíaa, Cristina Sangoa, Ana Isabel Martinez-Díaza, Marta Arias-Guilléna, Manel Veraa, Néstor Fontseréa, Miquel Gómeza, Lida Rodasa, Nayra Ricob
a Servicio de Nefrología, Hospital Clínic, Barcelona, Spain
b Servicio de Bioquímica, Hospital Clínic, Barcelona, Spain
Read
10306
Times
was read the article
3205
Total PDF
7101
Total HTML
Share statistics
 array:25 [
  "pii" => "S2013251417301992"
  "issn" => "20132514"
  "doi" => "10.1016/j.nefroe.2017.11.015"
  "estado" => "S300"
  "fechaPublicacion" => "2018-01-01"
  "aid" => "365"
  "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
  "copyrightAnyo" => "2017"
  "documento" => "article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:34-40"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4239
    "formatos" => array:3 [
      "EPUB" => 316
      "HTML" => 3274
      "PDF" => 649
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0211699517300711"
      "issn" => "02116995"
      "doi" => "10.1016/j.nefro.2017.03.013"
      "estado" => "S300"
      "fechaPublicacion" => "2018-01-01"
      "aid" => "365"
      "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
      "documento" => "article"
      "crossmark" => 0
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2018;38:34-40"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 4663
        "formatos" => array:3 [
          "EPUB" => 260
          "HTML" => 3592
          "PDF" => 811
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "34"
            "paginaFinal" => "40"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Evaluation of the dialyser inner diameter in online haemodiafiltration"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 1310
                "Ancho" => 1625
                "Tamanyo" => 75600
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variaciones en la dosis de di&#225;lisis&#44; medidas por dialisancia i&#243;nica&#44; expresada como litros de Kt en las diferentes situaciones de estudio &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA para datos repetidos&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Francisco Maduell, Raquel Ojeda, Lara Belmar, Paula Mungu&#237;a, Cristina Sango, Ana Isabel Martinez-D&#237;az, Marta Arias-Guill&#233;n, Manel Vera, N&#233;stor Fontser&#233;, Miquel G&#243;mez, Lida Rodas, Nayra Rico"
            "autores" => array:12 [
              0 => array:2 [
                "nombre" => "Francisco"
                "apellidos" => "Maduell"
              ]
              1 => array:2 [
                "nombre" => "Raquel"
                "apellidos" => "Ojeda"
              ]
              2 => array:2 [
                "nombre" => "Lara"
                "apellidos" => "Belmar"
              ]
              3 => array:2 [
                "nombre" => "Paula"
                "apellidos" => "Mungu&#237;a"
              ]
              4 => array:2 [
                "nombre" => "Cristina"
                "apellidos" => "Sango"
              ]
              5 => array:2 [
                "nombre" => "Ana Isabel"
                "apellidos" => "Martinez-D&#237;az"
              ]
              6 => array:2 [
                "nombre" => "Marta"
                "apellidos" => "Arias-Guill&#233;n"
              ]
              7 => array:2 [
                "nombre" => "Manel"
                "apellidos" => "Vera"
              ]
              8 => array:2 [
                "nombre" => "N&#233;stor"
                "apellidos" => "Fontser&#233;"
              ]
              9 => array:2 [
                "nombre" => "Miquel"
                "apellidos" => "G&#243;mez"
              ]
              10 => array:2 [
                "nombre" => "Lida"
                "apellidos" => "Rodas"
              ]
              11 => array:2 [
                "nombre" => "Nayra"
                "apellidos" => "Rico"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2013251417301992"
          "doi" => "10.1016/j.nefroe.2017.11.015"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417301992?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517300711?idApp=UINPBA000064"
      "url" => "/02116995/0000003800000001/v1_201801090621/S0211699517300711/v1_201801090621/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2013251418300026"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2018.01.002"
    "estado" => "S300"
    "fechaPublicacion" => "2018-01-01"
    "aid" => "396"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:41-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6113
      "formatos" => array:3 [
        "EPUB" => 296
        "HTML" => 5154
        "PDF" => 663
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Correction of 25-OH-vitamin D deficiency improves control of secondary hyperparathyroidism and reduces the inflammation in stable haemodialysis patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "41"
          "paginaFinal" => "47"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "La correcci&#243;n del d&#233;ficit de 25-OH-vitamina D mejora el control del hiperparatiroidismo secundario y el estado inflamatorio de pacientes estables en hemodi&#225;lisis"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0020"
          "etiqueta" => "Fig&#46; 4"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr4.jpeg"
              "Alto" => 1362
              "Ancho" => 2669
              "Tamanyo" => 145520
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Determination of microinflammation in patients&#44; before and after treatment&#44; given as the percentage of activated monocytes &#40;CD14&#43;&#47;CD16&#43;&#41; before and after treatment &#40;A&#41; and as the levels of C-reactive protein &#40;CRP&#41; &#40;B&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Raquel Ojeda L&#243;pez, Elvira Esquivias de Motta, Andr&#233;s Carmona, Victoria Garc&#237;a Montemayor, Isabel Berdud, Alejandro Mart&#237;n Malo, Pedro Aljama Garc&#237;a"
          "autores" => array:7 [
            0 => array:2 [
              "nombre" => "Raquel"
              "apellidos" => "Ojeda L&#243;pez"
            ]
            1 => array:2 [
              "nombre" => "Elvira"
              "apellidos" => "Esquivias de Motta"
            ]
            2 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Carmona"
            ]
            3 => array:2 [
              "nombre" => "Victoria"
              "apellidos" => "Garc&#237;a Montemayor"
            ]
            4 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Berdud"
            ]
            5 => array:2 [
              "nombre" => "Alejandro"
              "apellidos" => "Mart&#237;n Malo"
            ]
            6 => array:2 [
              "nombre" => "Pedro"
              "apellidos" => "Aljama Garc&#237;a"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699517301315"
        "doi" => "10.1016/j.nefro.2017.05.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517301315?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251418300026?idApp=UINPBA000064"
    "url" => "/20132514/0000003800000001/v1_201802180616/S2013251418300026/v1_201802180616/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S2013251417302158"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2017.04.018"
    "estado" => "S300"
    "fechaPublicacion" => "2018-01-01"
    "aid" => "383"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "ssu"
    "cita" => "Nefrologia &#40;English Version&#41;. 2018;38:27-33"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3003
      "formatos" => array:3 [
        "EPUB" => 269
        "HTML" => 2196
        "PDF" => 538
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Brief review</span>"
      "titulo" => "Advances in the evaluation of bone health in kidney transplant patients"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "27"
          "paginaFinal" => "33"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Avances en la valoraci&#243;n de la salud &#243;sea en el trasplantado renal"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1981
              "Ancho" => 2865
              "Tamanyo" => 281712
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Comparison between the different diagnostic tests to estimate bone health&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mar&#237;a Jos&#233; P&#233;rez-S&#225;ez, Daniel Prieto-Alhambra, Adolfo D&#237;ez-P&#233;rez, Julio Pascual"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mar&#237;a Jos&#233;"
              "apellidos" => "P&#233;rez-S&#225;ez"
            ]
            1 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Prieto-Alhambra"
            ]
            2 => array:2 [
              "nombre" => "Adolfo"
              "apellidos" => "D&#237;ez-P&#233;rez"
            ]
            3 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Pascual"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699517301030"
        "doi" => "10.1016/j.nefro.2017.04.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699517301030?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417302158?idApp=UINPBA000064"
    "url" => "/20132514/0000003800000001/v1_201802180616/S2013251417302158/v1_201802180616/en/main.assets"
  ]
  "en" => array:21 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
    "titulo" => "Evaluation of the dialyzer inner diameter in online haemodiafiltration"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "34"
        "paginaFinal" => "40"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Francisco Maduell, Raquel Ojeda, Lara Belmar, Paula Mungu&#237;a, Cristina Sango, Ana Isabel Martinez-D&#237;az, Marta Arias-Guill&#233;n, Manel Vera, N&#233;stor Fontser&#233;, Miquel G&#243;mez, Lida Rodas, Nayra Rico"
        "autores" => array:12 [
          0 => array:4 [
            "nombre" => "Francisco"
            "apellidos" => "Maduell"
            "email" => array:1 [
              0 => "fmaduell&#64;clinic&#46;ub&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Raquel"
            "apellidos" => "Ojeda"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Lara"
            "apellidos" => "Belmar"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Paula"
            "apellidos" => "Mungu&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Cristina"
            "apellidos" => "Sango"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Ana Isabel"
            "apellidos" => "Martinez-D&#237;az"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Marta"
            "apellidos" => "Arias-Guill&#233;n"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          7 => array:3 [
            "nombre" => "Manel"
            "apellidos" => "Vera"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          8 => array:3 [
            "nombre" => "N&#233;stor"
            "apellidos" => "Fontser&#233;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          9 => array:3 [
            "nombre" => "Miquel"
            "apellidos" => "G&#243;mez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          10 => array:3 [
            "nombre" => "Lida"
            "apellidos" => "Rodas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          11 => array:3 [
            "nombre" => "Nayra"
            "apellidos" => "Rico"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Hospital Cl&#237;nic&#44; Barcelona&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Bioqu&#237;mica&#44; Hospital Cl&#237;nic&#44; Barcelona&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1310
            "Ancho" => 1625
            "Tamanyo" => 79063
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variations in the dose of dialysis&#44; measured by ionic dialysance&#44; expressed as liters of Kt in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">On-line hemodiafiltration &#40;OL-HDF&#41; with a high volume of replacement combines diffusive with convective treatment&#44; allows a greater clearance of solutes of medium and high molecular weight and improves intradialysis hemodynamic tolerance&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;2</span></a> The ESHOL<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">3</span></a> study demonstrated that post-dilution OL-HDF reduces mortality from any cause with respect to hemodialysis &#40;HD&#41; in prevalent patients on HD&#46; The inclusion of the main randomized clinical trials in a pooling project with more than 2700 patients<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">4</span></a> and several meta-analysis<a class="elsevierStyleCrossRefs" href="#bib0155"><span class="elsevierStyleSup">5&#44;6</span></a> has confirmed the reduction in overall and cardiovascular mortality&#46; In a post hoc analysis&#44; the 3 clinical trials that had mortality as the main variable<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#44;7&#44;8</span></a> observed an association between convective volume and survival&#46; Taking into consideration these results&#44; it has been recommended to achieve a replacement volume greater than 21<span class="elsevierStyleHsp" style=""></span>L&#47;session&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">9</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The main factors limiting the achievement of high convective volumes are blood flow &#40;Qb&#41;&#44; time and dialyzer&#46; The pharmaceutical industry has improved the dialyzers optimizing the pore size to obtain greater volumes of substitution and greater purification&#46;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">10&#44;11</span></a> However&#44; the question of the effect of inner diameter of the capillary fibers of these dialyzers is contradictory&#46; In the year 2000&#44; Ronco et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a> in an in vitro and in vivo study in HD&#44; showed that the reduction of the inner diameter was associated with an increase in proximal filtration and a distal backfiltration&#44; which improved the removal of large molecules&#44; through a greater internal convective volume&#46; They recommended reducing the inside diameter from 200<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;standard in those years&#41; to a lower one&#44; provided that an ultrapure dialysis fluid was available&#46; However&#44; with the progressive advance of OL-HDF&#44; the pharmaceutical industry offers again capillary fibers with a higher inner diameter&#44; probably to reduce the pressure of blood entering the dialyzer&#44; since&#44; in some monitors&#44; it conditions the transmembrane pressure&#46; To clarify this issue&#44; the present study was performed to determine the effect of increasing the inner diameter of the capillary fibers on convective volume and depurative capacity&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">Study performed in one single center in stable patients on OL-HDF&#46; We included 16 patients &#40;12 men and 4 women&#41; with a mean age of 64&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13 years &#40;range 42&#8211;91 years&#41; who were in the HD program for an average of 64<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>67 months &#40;interval 5&#8211;251 months&#41;&#46; The etiology of chronic renal failure was chronic glomerulonephritis &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#41; &#40;10&#46;8&#37;&#41;&#44; diabetic nephropathies &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41; &#40;8&#46;1&#37;&#41;&#44; polycystic kidney disease &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#41; &#40;5&#46;4&#37;&#41;&#44; vascular nephropathies &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#41; &#40;5&#46;4&#37;&#41;&#44; urological causes &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41; &#40;8&#46;1&#37;&#41;&#44; systemic disease &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#41; &#40;2&#46;7&#37;&#41; and unknown etiology &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#41; &#40;2&#46;7&#37;&#41;&#46; All patients were dialyzed through arteriovenous fistula except one&#44; which was dialyzed through a prosthetic fistula&#46; The anticoagulation used was heparin of low molecular weight &#40;tinzaparin&#41; in 50&#37;&#44; heparin sodium in 25&#37; of the patients and the remaining 25&#37; were dialyzed without heparin&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Each patient was analyzed in 4 sessions&#44; always mid-week&#44; in which the inner diameter of the capillary fibers of the dialyzer was changed&#58; 185<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX60 Cordiax and FX80 Cordiax&#41; vs&#46; 210<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX600 Cordiax and FX800 Cordiax&#41;&#46; The characteristics of the dialyzers are shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; The dialysis parameters were kept constant in each of the studied sessions&#58; helixone plus membrane&#59; dialysis time&#44; 293<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17<span class="elsevierStyleHsp" style=""></span>min &#40;240&#8211;300<span class="elsevierStyleHsp" style=""></span>min&#41;&#59; dialysate flow &#40;Qd&#41; 400<span class="elsevierStyleHsp" style=""></span>mL&#47;min and monitor 5008 Cordiax&#44; post-dilution OL-HDF with auto-substitution system&#46; The order of the sessions was randomized&#46; The dialysis parameters collected in each session were&#58; programmed time&#44; real duration&#44; dialyzer&#44; Qb&#44; Qd&#44; caliber of the needles&#44; Kt automatically measured by ionic dialysance&#44; recirculation index measured by the temperature module&#44; arterial pressure&#44; venous pressure&#44; transmembrane pressure&#44; initial and final hematocrit&#44; ultrafiltration&#44; volume of blood processed and substitution volume&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Laboratory measurements included the concentrations of urea &#40;60<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; creatinine &#40;113<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#946;<span class="elsevierStyleInf">2</span>-microglobulin &#40;11&#44;800<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; myoglobin &#40;17&#44;200<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; prolactin &#40;23&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin &#40;33&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&#44; &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein &#40;41&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41; and albumin &#40;66&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41; in serum at the beginning and at the end of each session to calculate the percentage reduction of these solutes&#46; The final concentration of &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; myoglobin&#44; prolactin&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin&#44; &#945;<span class="elsevierStyleInf">1</span>-glycoprotein and albumin were corrected for the degree of hemoconcentration and the volume of distribution &#40;approximately extracellular volume&#41; according to Bergstr&#246;m and Wehle&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">13</span></a> Urea&#44; creatinine and albumin concentrations were measured by molecular absorption spectrometry on the ADVIA 2400 analyzer &#40;Chemistry System from Siemens Healthineers&#44; Tarrytown&#44; USA&#41;&#46; &#946;<span class="elsevierStyleInf">2</span>-microglobulin and &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein were measured by immunonephelometry with the Dimension Vista analyzer &#40;Siemens Healthineers&#41; and &#945;<span class="elsevierStyleInf">1</span>-microglobulin by immunonephelometry with the BNII analyzer &#40;Siemens Healthineers&#41;&#46; Myoglobin concentrations were measured by &#8220;sandwich&#8221; enzyme immunoassays with the Dimension EXL analyzer &#40;Siemens Healthineers&#41;&#46; Prolactin concentrations were measured by &#8220;sandwich&#8221; enzyme immunoassay with the ADVIA Centaur analyzer &#40;Siemens Healthineers&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">In all cases&#44; specific reagents were used&#46; The reference values in our laboratory are 10&#8211;50<span class="elsevierStyleHsp" style=""></span>mg&#47;dL for urea&#44; 0&#46;3&#8211;1&#46;3<span class="elsevierStyleHsp" style=""></span>mg&#47;dL for creatinine&#44; 0&#46;1&#8211;2&#46;3<span class="elsevierStyleHsp" style=""></span>mg&#47;L for &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; 0&#8211;100<span class="elsevierStyleHsp" style=""></span>ng&#47;mL for myoglobin&#44; 2&#46;8&#8211;15<span class="elsevierStyleHsp" style=""></span>ng&#47;mL for prolactin&#44; 5&#8211;25<span class="elsevierStyleHsp" style=""></span>mg&#47;L for &#945;<span class="elsevierStyleInf">1</span>-microglobulin&#44; 0&#46;38&#8211;1&#46;18<span class="elsevierStyleHsp" style=""></span>g&#47;L for &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein and 34&#8211;48<span class="elsevierStyleHsp" style=""></span>g&#47;L for albumin&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Likewise&#44; a proportional part of the dialysis fluid was collected to quantify the loss of solutes and also of albumin&#46; Urea&#44; creatinine and prolactin were measured as in serum&#46; However&#44; since the concentrations of &#946;<span class="elsevierStyleInf">2</span>-microglobulin and albumin were very low&#44; it was necessary to analyze these values with the same technology&#44; but with the methods of determination used in urine samples to increase the analytical sensitivity&#46; The &#946;<span class="elsevierStyleInf">2</span>-microglobulin was measured with more sensitive method&#58; 0&#46;004625<span class="elsevierStyleHsp" style=""></span>mg&#47;L&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The results are expressed as the arithmetic mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#46; For the analysis of the statistical significance of quantitative parameters&#44; the Student t test for paired data and ANOVA for repeated data were used&#46; A <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;05 was considered statistically significant&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0045" class="elsevierStylePara elsevierViewall">All dialysis sessions were performed without notable clinical incidents&#46; Clothing of the lines or dialyzed was not observed&#46; There were no differences in dialysis parameters&#58; Qb&#44; total blood processed according to the monitor&#44; Qd&#44; real duration of sessions&#44; initial weight&#44; final weight&#44; weight gain&#44; measurements by the dialysis monitor of the initial and final hematocrit&#44; size of the needles&#44; recirculation of the vascular access&#44; arterial pressure&#44; venous pressure or transmembrane pressure &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">The increase in inner diameter in the 2 series of comparisons did not show an increase in the replacement volume &#40;29&#46;61<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33&#46;5 with FX60 Cordiax vs&#46; 29&#46;07<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>33&#46;8<span class="elsevierStyleHsp" style=""></span>L&#47;session with FX600 Cordiax and 30&#46;99<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5 with FX80 Cordiax vs&#46; 30&#46;83<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1<span class="elsevierStyleHsp" style=""></span>L&#47;session with FX800 Cordiax&#41;&#59; and&#44; as expected&#44; the total convective volume was not changed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">The difference in the inner diameter of the dialysis fibers did not produce significant effect in the dialysis dose&#44; expressed as Kt &#40;71&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;7 with FX60 Cordiax vs&#46; 73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;9<span class="elsevierStyleHsp" style=""></span>L with FX600 Cordiax and 72&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>70 with FX80 Cordiax vs&#46; 74&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;7<span class="elsevierStyleHsp" style=""></span>L with FX800 Cordiax&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; nor as the percentage of urea reduction &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">The percent reduction of the rest of the solutes &#40;creatinine&#44; &#946;<span class="elsevierStyleInf">2</span>-microglobulin&#44; myoglobin&#44; prolactin&#44; &#945;<span class="elsevierStyleInf">1</span>-microglobulin and &#945;<span class="elsevierStyleInf">1</span>-acid glycoprotein&#41; is shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46; Neither&#44; the inner diameter of the fibers nor the 2 types of dialyzers being compared produces a significant difference in the percent reduction of solutes&#46; No significant differences were observed in the albumin eliminated through the dialysate in any of the 2 comparison series&#58; 2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;8<span class="elsevierStyleHsp" style=""></span>g for FX60 Cordiax vs&#46; 1&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX600 Cordiax and 3&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX80 Cordiax vs&#46; 3&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9<span class="elsevierStyleHsp" style=""></span>g with FX800 Cordiax&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0065" class="elsevierStylePara elsevierViewall">The present study shows that&#44; in post-dilution OL-HDF&#44; the comparison of 2 series of dialyzers with inner capillary fiber diameters of 185 and 210<span class="elsevierStyleHsp" style=""></span>&#956;m showed no differences on convective volume and depurative efficacy&#46; After reviewing the literature&#44; this study represents the first study in OL-HDF in which the inner diameter is compared without changing the rest of the dialysis parameters&#46; The convective volume reached&#44; which varied between 29 and 31<span class="elsevierStyleHsp" style=""></span>L&#47;session&#44; was adequate&#44; although no statistically significant differences were observed in any of the 2 standards compared&#46; In terms of efficacy&#44; no significant differences were observed in the reduction of solutes of small and high molecular weight&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">The effectiveness of HD treatment is measured in terms of survival&#44; morbidity and quality of life obtained during both the dialysis session and the interdialysis period&#46; OL-HDF combines diffusive transport and allows a considerable increase in convective transport&#44;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">14</span></a> with a greater clearance of medium and high molecular weight toxins&#46;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">15&#44;16</span></a> OL-HDF is a safe technique that improves intradialysis hemodynamic tolerance<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">1&#44;3</span></a> contributing&#44; among others&#44; to the correction of anemia&#44; the chronic inflammation&#44; amyloidosis&#44; hyperparathyroidism&#44; oxidative stress and the lipid profile&#44;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">17&#8211;19</span></a> and increases survival<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">3&#8211;6</span></a> and quality of life&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">4&#44;20</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">During the last few years&#44; new dialyzers have been developed with greater surface area&#44; better geometric arrangement of capillary fibers&#44; variation of wall thickness&#44; larger pore size&#44; in order to achieve greater removal of both small and medium-large molecules&#46; The ideal hemodialyzer should achieve the following characteristics&#58; high clearance of small molecules&#59; high sieving coefficient for &#946;<span class="elsevierStyleInf">2</span>-microglobulin and myoglobin&#59; low sieving coefficient for albumin&#59; low transmembrane pressures that do not limit the infusion flow&#59; great power to trap endotoxins and a good price&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">21</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">The convective capacity of the dialyzers follows the Hagen&#8211;Poiseuille law&#44; &#916;p&#8201;&#61;&#8201;Qb&#215;8&#951;l&#47;&#960;r4&#44; the drop of pressure inside the dialyzer fiber is directly proportional to the Qb&#44; the length<span class="elsevierStyleSup">l</span> and the blood viscosity and inversely proportional to the inner diameter&#46; A pressure drop inside the fiber will increase the pressure gradient between the blood compartment and the dialysis compartment&#44; leading to greater convective transport&#46; Taking into account that&#44; a minimum reduction in the diameter of the capillary fiber has a great impact on the pressure drop inside the capillary fiber that will increase the pressure gradient between the blood and the dialysis fluid along the entire length of the fiber&#44; with improvement of both diffusion and convection&#46; In terms of efficacy&#44; while the increase in diffusion hardly implies variation in the clearance of small molecules&#44; a greater convective transport causes a greater clearance of f high molecular weight molecules&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In a previous study<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">22</span></a> it was shown that the increase in Qb is probably the best method to reach the highest convective volume&#46; For every 50<span class="elsevierStyleHsp" style=""></span>mL&#47;min of Qb increase&#44; the convective volume increases more than half a liter per hour&#46; The Qb increases the removal capacity of small molecules and favors that of &#946;<span class="elsevierStyleInf">2</span>-microglobulin and myoglobin&#46; In another study<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">23</span></a> the effect of increasing the dialyzer surface was evaluated&#44; and it was concluded that the increase in the dialyzer surface caused a small increase in the convective volume without evidencing an improvement in the removal capacity&#44; especially if the ultrafiltration coefficient was higher at 45<span class="elsevierStyleHsp" style=""></span>mL&#47;h&#47;mmHg&#46; In the present study&#44; we did not observe significant variations of convective volume in any of the 2-series compared&#46; Unlike the previous study&#44; in our study&#44; in addition to an increase in the inner diameter of the capillary fiber from 185<span class="elsevierStyleHsp" style=""></span>&#956;m to 210<span class="elsevierStyleHsp" style=""></span>&#956;m&#44; there was a small increase of 0&#46;2<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> in the surface of the dialyzer &#40;1&#46;4<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 60 vs&#46; 1&#46;6<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 600 and 1&#46;8<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 80 vs&#46; 2&#46;0<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> for FX CorDiax 800&#41;&#46; Therefore&#44; the non-variation observed in the convective volume may be the result of the opposite variations of simultaneous increase in area and diameter that can compensate for each other&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">The publications on the effects of the variation of the inner diameter of the capillary fibers in relation to the convective volume and the removal capacity of the dialyzers are limited&#46; Dellanna et al&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">24</span></a> tested in 10 high-flow HD patients 3 types of polysulfone dialyzers with identical number and length of fibers&#44; with inner diameters of 175&#44; 200 and 250<span class="elsevierStyleHsp" style=""></span>&#956;m&#44; surfaces of 0&#46;55&#44; 0&#46;65 and 0&#46;79<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> respectively&#44; and sieving coefficients for &#946;<span class="elsevierStyleInf">2</span>-microglobulin 0&#46;82&#44; 0&#46;79 and 0&#46;71&#44; respectively&#46; With Qb 250 and Qd 500<span class="elsevierStyleHsp" style=""></span>mL&#47;min they hardly observe any variation in the clearance of small molecules such as urea or creatinine&#46; By contrast&#44; the dialyzer with the smallest diameter &#40;175<span class="elsevierStyleHsp" style=""></span>&#956;m&#41;&#44; despite having the smallest surface&#44; showed a clearance of &#946;<span class="elsevierStyleInf">2</span>-microglobulin twice that of the dialyzer of 200<span class="elsevierStyleHsp" style=""></span>&#956;m and almost 5&#46;6 times higher than that of 250<span class="elsevierStyleHsp" style=""></span>&#956;m&#46; Ronco et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">12</span></a> also in HD&#44; compared in vitro and in vivo 2 types of high flow dialyzers with hollow fiber of polysulfone&#44; of 0&#46;7<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> of surface&#44; the standard with a diameter of 200<span class="elsevierStyleHsp" style=""></span>&#956;m and another modified to an inner diameter of 175<span class="elsevierStyleHsp" style=""></span>&#956;m&#46; With dialysis parameters of Qb 300 and Qd 500<span class="elsevierStyleHsp" style=""></span>mL&#47;min in vitro&#44; it was observed an increase in internal filtration and backfiltration from 23&#46;1<span class="elsevierStyleHsp" style=""></span>mL&#47;min in the fibers of 200<span class="elsevierStyleHsp" style=""></span>&#956;m diameter to 48&#46;2<span class="elsevierStyleHsp" style=""></span>mL&#47;min in the 175<span class="elsevierStyleHsp" style=""></span>&#956;m dialyzer&#46; The in vivo studies showed that the reduction in inner diameter produced an increase of 30&#37; in the clearance of intermediate solutes such as vitamin B12 or inulin&#46; Similar results were obtained by Mineshima et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a> In an analytical-experimental study they analyzed the effects of the inner diameter of the capillary fibers on the internal filtration and the efficiency in the elimination of solutes in HD&#46; They evaluated 5 dialyzers of the same surface &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span>&#41; and inner diameters of 150&#44; 175 and 3 sessions with 200<span class="elsevierStyleHsp" style=""></span>&#956;m varying the number and length of the capillary fibers&#46; They observed that a decrease in the inner diameter of the capillary fibers increased internal filtration and increased the clearance of myoglobin&#46; In this same study they show that an excessive reduction of the inner diameter may increase the risk of hemolysis and transfer of biological contaminants&#44; so they proposed that the reduction of the inner diameter should not produce an internal pressure drop superior to 150<span class="elsevierStyleHsp" style=""></span>mmHg&#44; for the patient&#39;s own safety&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">25</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">We have not found in the literature comparative studies of the inner diameter in OL-HDF&#46; In a study that analyzed the factors associated with the achievement a greater convective volume&#44; Marcelli et al&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">26</span></a> observed a convective volume of 25&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1<span class="elsevierStyleHsp" style=""></span>L in 325 patients with FX60 as compared to 27&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6<span class="elsevierStyleHsp" style=""></span>L in 2572 patients with FX600&#46; However&#44; these 2&#46;2<span class="elsevierStyleHsp" style=""></span>L of difference cannot be attributed to the change in inner diameter but to the increase in Qb &#40;352<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>54 vs&#46; 361<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>70<span class="elsevierStyleHsp" style=""></span>mL&#47;min&#41; and to the duration of treatment &#40;241<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11 vs&#46; 255<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>19<span class="elsevierStyleHsp" style=""></span>min&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">We conclude that the increase of the inner diameter of the capillary fibers in OL-HDF has not produced a greater efficiency in the convective volume nor in the depurative capacity&#46; Therefore&#44; the inner diameter in dialyzers with high ultrafiltration coefficient does not seem to be a limiting factor in convective volume&#44; as it is the blood flow or dialysis time&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflicts of interest</span><p id="par0105" class="elsevierStylePara elsevierViewall">The authors declare to have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres985571"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Material and methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusion"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec953223"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres985572"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Introducci&#243;n"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Material y m&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusi&#243;n"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec953224"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discussion"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflicts of interest"
        ]
        9 => array:2 [
          "identificador" => "xack334117"
          "titulo" => "Acknowledgements"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2017-02-08"
    "fechaAceptado" => "2017-03-16"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec953223"
          "palabras" => array:4 [
            0 => "Dialyzer"
            1 => "Inner diameter"
            2 => "Online haemodiafiltration"
            3 => "Convective volume"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec953224"
          "palabras" => array:4 [
            0 => "Dializador"
            1 => "Di&#225;metro interno"
            2 => "Hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>"
            3 => "Volumen convectivo"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Online haemodiafiltration &#40;OL-HDF&#41; has been associated with increased survival&#46; To date&#44; the influence of the inner diameter of the hollow fibers of the dialyzer on convective volume has not been well established&#46; The objective of the study was to evaluate the effect of increasing the inner diameter of the dialyzer on the convective volume and removal capacity&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We included 16 patients in postdilutional OL-HDF&#46; Each patient was analyzed in 4 sessions in which the inner diameter varied&#59; 185<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX60 Cordiax and FX80 Cordiax&#41; vs&#46; 210<span class="elsevierStyleHsp" style=""></span>&#956;m &#40;FX600 Cordiax and FX800 Cordiax&#41;&#46; Different solutes were measured at the beginning and end of each dialysis session&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No differences in the convective volume were found with an increased inner diameter&#58; 32&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;1 vs&#46; 31&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;6<span class="elsevierStyleHsp" style=""></span>L&#47;session &#40;FX60 vs&#46; FX600&#41; and 33&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3 vs&#46; 33&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8<span class="elsevierStyleHsp" style=""></span>L&#47;session &#40;FX80 vs&#46; FX800&#41;&#46; The reduction ratios also did not differ&#58; urea 83&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5 vs&#46; 84&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;4 for FX60 and FX600&#44; and 82&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1 vs&#46; 83&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8 for FX80 vs&#46; FX800&#59; creatinine similar 78&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6 vs&#46; 77&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6 and 77&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4 vs&#46; 78&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&#59; &#946;<span class="elsevierStyleInf">2</span>-microglobulin 82&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3 vs&#46; 82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;2&#44; and 82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;7 vs&#46; 84&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&#59; myoglobin 71&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 70&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9 and 72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11 vs&#46; 75&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#59; prolactin 70&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9 vs&#46; 68&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44; and 72&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&#59; and &#945;<span class="elsevierStyleInf">1</span>-microglobulin 22&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10 vs&#46; 21&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#44; and 26&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12 vs&#46; 28&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#44; respectively&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The increase in the inner diameter of the hollow fibers did not result in improved convective volume and removal capacity&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusion"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Se ha asociado la hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span> &#40;HDF-OL&#41; a un aumento de la supervivencia&#46; Hasta el momento no est&#225; bien establecida la influencia del di&#225;metro interno de las fibras capilares del dializador sobre la capacidad convectiva&#46; El objetivo del estudio fue valorar el efecto del aumento del di&#225;metro interno del dializador sobre el volumen convectivo y la capacidad depurativa&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Material y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 16 pacientes en HDF-OL posdilucional con reposici&#243;n autom&#225;tica&#46; Cada paciente recibi&#243; 4 sesiones&#44; en las que se vari&#243; el di&#225;metro interno&#44; 185 &#956;m &#40;FX60 Cordiax y FX80 Cordiax&#41; versus 210 &#956;m &#40;FX600 Cordiax y FX800 Cordiax&#41;&#46; En cada sesi&#243;n se determinaron diferentes solutos al inicio y al final de la di&#225;lisis&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">El incremento de di&#225;metro interno entre FX60 vs&#46; FX600 y FX80 vs&#46; FX800 no reflej&#243; diferencias en el volumen convectivo&#58; 32&#44;3 &#177; 3&#44;1 vs&#46; 31&#44;8 &#177; 3&#44;6 y 33&#44;7 &#177; 4&#44;3 vs&#46; 33&#44;5 &#177; 3&#44;8 L&#47;sesi&#243;n&#44; respectivamente&#46; Los porcentajes de reducci&#243;n tampoco mostraron diferencias&#58; urea 83&#44;7 &#177; 4&#44;5 vs&#46; 84&#44;1 &#177; 3&#44;4 para FX60 y FX600 y 82&#44;7 &#177; 4&#44;1 vs&#46; 83&#44;6 &#177; 3&#44;8 para FX80 vs&#46; FX800&#59; creatinina similar 78&#44;2 &#177; 5&#44;6 vs&#46; 77&#44;8 &#177; 4&#44;6 y 77&#44;1 &#177; 5&#44;4 vs&#46; 78&#44;1 &#177; 4&#44;9&#59; &#946;<span class="elsevierStyleInf">2</span>-microglobulina 82&#44;2 &#177; 4&#44;3 vs&#46; 82&#44;9 &#177; 4&#44;2 y 82&#44;9 &#177; 4&#44;7 vs&#46; 84&#44;0 &#177; 3&#44;8&#59; mioglobina 71&#44;0 &#177; 10&#44; vs&#46; 70&#44;2 &#177; 9 y 72&#44;8 &#177; 11 vs&#46; 75&#44;0 &#177; 10&#59; prolactina 70&#44;4 &#177; 9 vs&#46; 68&#44;1 &#177; 9 y 72&#44;2 &#177; 10 vs&#46; 73&#44;4 &#177; 8&#44;2&#59; y &#945;<span class="elsevierStyleInf">1</span>-microglobulina 22&#44;9 &#177; 10 vs&#46; 21&#44;6 &#177; 10 y 26&#44;5 &#177; 12 vs&#46; 28&#44;8 &#177; 11&#44; respectivamente&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusi&#243;n</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El incremento del di&#225;metro interno de las fibras capilares no ha significado una mayor eficacia en el volumen convectivo ni en la capacidad depurativa&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introducci&#243;n"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Material y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusi&#243;n"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Maduell F&#44; Ojeda R&#44; Belmar L&#44; Mungu&#237;a P&#44; Sango C&#44; Martinez-D&#237;az AI&#44; et al&#46; Valoraci&#243;n del di&#225;metro interno del dializador en hemodiafiltraci&#243;n <span class="elsevierStyleItalic">on-line</span>&#46; Nefrologia&#46; 2018&#59;38&#58;34&#8211;40&#46;</p>"
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1182
            "Ancho" => 1617
            "Tamanyo" => 75823
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Variations in convective volume during on line hemodiafiltration in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1310
            "Ancho" => 1625
            "Tamanyo" => 79063
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Variations in the dose of dialysis&#44; measured by ionic dialysance&#44; expressed as liters of Kt in the different study situations &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>16&#41; ANOVA for repeated measurements&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">KUF&#58; ultrafiltration coefficient&#59; KoA&#58; mass transfer coefficient&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Membrane<br>Surface &#40;m<span class="elsevierStyleSup">2</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Helixone<span class="elsevierStyleSup">&#174;</span>plus 2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Wall thickness &#40;&#956;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Inner diameter &#40;&#956;m&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">210&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">210&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KoA urea &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1164&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1148&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1429&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1365&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KUF &#40;mL&#47;h&#47;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">KUF &#40;mL&#47;h&#47;mmHg&#47;m<span class="elsevierStyleSup">2</span>&#41;<br>Sterilization&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">33&#46;6<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&#46;8<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#46;6<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">31&#46;0<br>Steam&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sieving coefficient &#946;<span class="elsevierStyleInf">2</span>-microglobulin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sieving coefficient myoglobin<br>Sieving coefficient albumin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#46;5<br>&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672082.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Characteristics of the dialyzers&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">NS&#58; no significant&#59; Qb&#58; blood flow&#59; Qd&#58; dialysate flow&#59; Td&#58; duration of dialysis&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Qd &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">400&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Qb &#40;mL&#47;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">453<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>34&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total blood processed &#40;L&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">128&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">127&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>13&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Needles&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15<span class="elsevierStyleHsp" style=""></span>G&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Recirculation &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">13&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Td &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">283&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">283&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">282&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">282&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Initial weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Final weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">69&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">70&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">69&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>17&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Weight gain &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Initial hematocrit &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">29&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Final hematocrit &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">35&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Arterial pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;233<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;232<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;234<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#8722;228<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Venous pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">234<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>26&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">235<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">223<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">226<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Transmembrane pressure &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">183<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">192<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">185<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">191<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672081.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Comparison of dialysis parameters during the 4 different sessions&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 600&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">FX CorDiax 800&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Urea &#40;60<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">83&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Creatinine &#40;113<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">78&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">78&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#946;<span class="elsevierStyleInf">2</span>-microglobulin &#40;11&#46;818<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Myoglobin &#40;17&#44;200<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">71&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">75&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Prolactin &#40;23&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">72&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">73&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#945;<span class="elsevierStyleInf">1</span>-microglobulin &#40;33&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">21&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>12&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">&#945;<span class="elsevierStyleInf">1</span>-acid glicoprotein &#40;41&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11&#46;5<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17&#46;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Albumin &#40;66&#44;000<span class="elsevierStyleHsp" style=""></span>Da&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8&#46;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Loss of albumin in dialysate &#40;g&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;0<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">NS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1672080.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Percent of solute reduction during hemodialysis&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:26 [
            0 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemofiltration and hemodiafiltration reduce intradialytic hypotension in ESRD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Locatelli"
                            1 => "P&#46; Altieri"
                            2 => "S&#46; Andrulli"
                            3 => "P&#46; Bolasco"
                            4 => "G&#46; Sau"
                            5 => "L&#46;A&#46; Pedrini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2010030280"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2010"
                        "volumen" => "21"
                        "paginaInicial" => "1798"
                        "paginaFinal" => "1807"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20813866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of high efficiency post-dilution on-line hemodiafiltration or conventional hemodialysis on residual renal function and left ventricular hypertrophy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Schiffl"
                            1 => "S&#46;M&#46; Lang"
                            2 => "R&#46; Fischer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11255-012-0336-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int Urol Nephrol"
                        "fecha" => "2013"
                        "volumen" => "45"
                        "paginaInicial" => "1389"
                        "paginaFinal" => "1396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23225079"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "ESHOL Study Group"
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "F&#46; Moreso"
                            2 => "M&#46; Pons"
                            3 => "R&#46; Ramos"
                            4 => "J&#46; Mora-Maci&#224;"
                            5 => "J&#46; Carreras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2012080875"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2013"
                        "volumen" => "24"
                        "paginaInicial" => "487"
                        "paginaFinal" => "497"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23411788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "HDF Pooling Project Investigators&#46; Sanne NDT&#46; Haemodiafiltration and mortality in end-stage kidney disease patients&#58; a pooled individual participant data analysis from four randomized controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;A&#46; Peters"
                            1 => "M&#46;L&#46; Bots"
                            2 => "B&#46; Canaud"
                            3 => "A&#46; Davenport"
                            4 => "M&#46;P&#46; Grooteman"
                            5 => "F&#46; Kircelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "2016"
                        "volumen" => "31"
                        "paginaInicial" => "978"
                        "paginaFinal" => "984"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical evidence on hemodiafiltration&#58; a systematic review and a meta-analysis"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "EUDIAL Group"
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46;M&#46; Mostovaya"
                            1 => "P&#46;J&#46; Blankestijn"
                            2 => "M&#46;L&#46; Bots"
                            3 => "A&#46; Covic"
                            4 => "A&#46; Davenport"
                            5 => "M&#46; Grooteman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Dial"
                        "fecha" => "2014"
                        "volumen" => "27"
                        "paginaInicial" => "119"
                        "paginaFinal" => "127"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24738146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Convective versus diffusive dialysis therapies for chronic kidney failure&#58; an updated systematic review of randomized controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Nistor"
                            1 => "S&#46;C&#46; Palmer"
                            2 => "J&#46;C&#46; Craig"
                            3 => "V&#46; Saglimbene"
                            4 => "M&#46; Vecchio"
                            5 => "A&#46; Covic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/j.ajkd.2013.12.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
                        "fecha" => "2014"
                        "volumen" => "63"
                        "paginaInicial" => "954"
                        "paginaFinal" => "967"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24434188"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of online hemodiafiltration on all-cause mortality and cardiovascular outcomes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;P&#46; Grooteman"
                            1 => "M&#46;A&#46; van den Dorpel"
                            2 => "M&#46;L&#46; Bots"
                            3 => "E&#46;L&#46; Penne"
                            4 => "N&#46;C&#46; van der Weerd"
                            5 => "A&#46;H&#46; Mazairac"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1681/ASN.2011121140"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "1087"
                        "paginaFinal" => "1096"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22539829"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022347603005808"
                          "estado" => "S300"
                          "issn" => "00223476"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mortality and cardiovascular events in online haemodiafiltration &#40;OL-HDF&#41; compared with high-flux dialysis&#58; results from the Turkish OL-HDF Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Ok"
                            1 => "G&#46; Asci"
                            2 => "H&#46; Toz"
                            3 => "E&#46;S&#46; Ok"
                            4 => "F&#46; Kircelli"
                            5 => "M&#46; Yilmaz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "2013"
                        "volumen" => "28"
                        "paginaInicial" => "192"
                        "paginaFinal" => "202"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emerging clinical evidence on online hemodiafiltration&#58; does volume of ultrafiltration matter&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46; Canaud"
                            1 => "S&#46;K&#46; Bowry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000346371"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "paginaInicial" => "55"
                        "paginaFinal" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23466380"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Elimination of large uremic toxins by a dialyzer specifically designed for high-volume convective therapies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "M&#46; Arias-Guillen"
                            2 => "N&#46; Fontser&#233;"
                            3 => "R&#46; Ojeda"
                            4 => "N&#46; Rico"
                            5 => "M&#46; Vera"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000358214"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2014"
                        "volumen" => "37"
                        "paginaInicial" => "125"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24662288"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experimental evaluation of flow and dialysis performance of hollow-fiber dialyzers with different packing densities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Hirano"
                            1 => "S&#46; Kida"
                            2 => "K&#46; Yamamoto"
                            3 => "K&#46; Sakai"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10047-011-0620-6"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Artif Organs"
                        "fecha" => "2012"
                        "volumen" => "15"
                        "paginaInicial" => "168"
                        "paginaFinal" => "175"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22116168"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of a reduced inner diameter of hollow fibers in hemodialyzers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Ronco"
                            1 => "A&#46; Brendolan"
                            2 => "A&#46; Lupi"
                            3 => "G&#46; Metry"
                            4 => "N&#46;W&#46; Levin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1755.2000.00230.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2000"
                        "volumen" => "58"
                        "paginaInicial" => "809"
                        "paginaFinal" => "817"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10916106"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "No change in corrected &#946;<span class="elsevierStyleInf">2</span>-microglobulin concentration after cuprophane hemodialysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Bergstr&#246;m"
                            1 => "B&#46; Wehle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1987"
                        "volumen" => "1"
                        "paginaInicial" => "628"
                        "paginaFinal" => "629"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2894556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The importance of convective transport"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Locatelli"
                            1 => "C&#46; Manzoni"
                            2 => "S&#46; Di Filippo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Kidney Int Suppl"
                        "fecha" => "2002"
                        "volumen" => "80"
                        "paginaInicial" => "115"
                        "paginaFinal" => "120"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of high-flux hemodialysis on clinical outcomes&#58; results of the HEMO study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;K&#46; Cheung"
                            1 => "N&#46;W&#46; Levin"
                            2 => "T&#46; Greene"
                            3 => "L&#46; Agodoa"
                            4 => "J&#46; Bailey"
                            5 => "G&#46; Beck"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Soc Nephrol"
                        "fecha" => "2003"
                        "volumen" => "14"
                        "paginaInicial" => "3251"
                        "paginaFinal" => "3263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14638924"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteocalcin and myoglobin removal in on-line hemodiafiltration versus low and high-flux hemodialysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "V&#46; Navarro"
                            2 => "M&#46;C&#46; Cruz"
                            3 => "E&#46; Torregrosa"
                            4 => "D&#46; Garcia"
                            5 => "V&#46; Simon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Kidney Dis"
                        "fecha" => "2002"
                        "volumen" => "40"
                        "paginaInicial" => "582"
                        "paginaFinal" => "589"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12200811"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Change from conventional haemodiafiltration to on-line haemodiafiltration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "C&#46; del Pozo"
                            2 => "H&#46; Garcia"
                            3 => "L&#46; Sanchez"
                            4 => "J&#46; Hdez-Jaras"
                            5 => "M&#46;D&#46; Albero"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "1999"
                        "volumen" => "14"
                        "paginaInicial" => "1202"
                        "paginaFinal" => "1207"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Online haemodiafiltration versus haemodialysis&#58; stable haematocrit with less erythropoietin and improvement of other relevant blood parameters"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46; Vaslaki"
                            1 => "L&#46; Major"
                            2 => "K&#46; Berta"
                            3 => "A&#46; Karatson"
                            4 => "M&#46; Misz"
                            5 => "F&#46; Pethoe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000090117"
                      "Revista" => array:6 [
                        "tituloSerie" => "Blood Purif"
                        "fecha" => "2006"
                        "volumen" => "24"
                        "paginaInicial" => "163"
                        "paginaFinal" => "173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16352871"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Online haemodiafiltration&#58; effective removal of high molecular weight toxins and improvement in clinical manifestations of chronic haemodialysis patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;T&#46; Kim"
                            1 => "C&#46; Yamamoto"
                            2 => "H&#46; Asabe"
                            3 => "T&#46; Sato"
                            4 => "T&#46; Takamiya"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nephrology &#40;Carlton&#41;"
                        "fecha" => "1996"
                        "volumen" => "2"
                        "numero" => "Suppl&#46; 1"
                        "paginaInicial" => "S183"
                        "paginaFinal" => "S186"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Can dialysis modality influence quality of life in chronic hemodialysis patients&#63; Low-flux hemodialysis versus high-flux hemodiafiltration&#58; a cross-over study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46; Kantartzi"
                            1 => "S&#46; Panagoutsos"
                            2 => "E&#46; Mourvati"
                            3 => "A&#46; Roumeliotis"
                            4 => "K&#46; Leivaditis"
                            5 => "V&#46; Devetzis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/0886022X.2012.743858"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ren Fail"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "paginaInicial" => "216"
                        "paginaFinal" => "221"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23176401"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparaci&#243;n de dializadores en hemodiafiltraci&#243;n en l&#237;nea"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "F&#46; Maduell"
                            1 => "V&#46; Navarro"
                            2 => "J&#46; Hern&#225;ndez-Jaras"
                            3 => "C&#46; Calvo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2000"
                        "volumen" => "20"
                        "paginaInicial" => "269"
                        "paginaFinal" => "276"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10917004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hemodiafiltraci&#243;n on-line con autosustituci&#243;n&#58; valoraci&#243;n de los cambios del flujo de sangre sobre el volumen convectivo y eficacia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "R&#46; Ojeda"
                            2 => "L&#46; Rodas"
                            3 => "N&#46; Rico"
                            4 => "N&#46; Fontser&#233;"
                            5 => "M&#46; Arias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3265/Nefrologia.pre2014.Sep.12726"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2015"
                        "volumen" => "35"
                        "paginaInicial" => "50"
                        "paginaFinal" => "57"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25611833"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Valoraci&#243;n de la superficie del dializador en la hemodiafiltraci&#243;n on-line&#46; Elecci&#243;n objetiva de la superficie del dializador"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Maduell"
                            1 => "R&#46; Ojeda"
                            2 => "M&#46; Arias-Guill&#233;n"
                            3 => "G&#46; Bazan"
                            4 => "M&#46; Vera"
                            5 => "N&#46; Fontser&#233;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nefro.2015.05.003"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nefrologia"
                        "fecha" => "2015"
                        "volumen" => "35"
                        "paginaInicial" => "280"
                        "paginaFinal" => "286"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26299171"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Internal filtration &#8211; advantage in haemodialysis&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Dellanna"
                            1 => "A&#46; Wuepper"
                            2 => "C&#46;A&#46; Baldamus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nephrol Dial Transpl"
                        "fecha" => "1996"
                        "volumen" => "11"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "83"
                        "paginaFinal" => "86"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of internal filtration on the solute removal efficiency of a dialyzer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Mineshima"
                            1 => "I&#46; Ishimori"
                            2 => "K&#46; Ishida"
                            3 => "T&#46; Hoshino"
                            4 => "I&#46; Kaneko"
                            5 => "Y&#46; Sato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "ASAIO J"
                        "fecha" => "2000"
                        "volumen" => "46"
                        "paginaInicial" => "456"
                        "paginaFinal" => "460"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10926146"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Modificable factors associated with achievement of high-volume post-dilution hemodiafiltration&#58; results of an international study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Marcelli"
                            1 => "P&#46; Kopperschmidt"
                            2 => "I&#46; Bayh"
                            3 => "T&#46; Jirka"
                            4 => "J&#46;I&#46; Merello"
                            5 => "P&#46; Ponce"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5301/ijao.5000414"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Artif Organs"
                        "fecha" => "2015"
                        "volumen" => "38"
                        "paginaInicial" => "244"
                        "paginaFinal" => "250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26080930"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack334117"
        "titulo" => "Acknowledgements"
        "texto" => "<p id="par0110" class="elsevierStylePara elsevierViewall">We would like to express our gratitude to all the patients who have participated&#44; as well as to all the staff of the Dialysis Section of the Hospital Cl&#237;nic of Barcelona for their collaboration and enthusiasm in this study&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003800000001/v1_201802180616/S2013251417301992/v1_201802180616/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "42660"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003800000001/v1_201802180616/S2013251417301992/v1_201802180616/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251417301992?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
DOI:10.1016/j.nefroe.2017.11.015
The statistics are updated each day
Year/Month Html Pdf Total
2024 October 63 54 117
2024 September 92 48 140
2024 August 90 78 168
2024 July 82 50 132
2024 June 93 45 138
2024 May 72 45 117
2024 April 83 40 123
2024 March 48 44 92
2024 February 53 39 92
2024 January 64 29 93
2023 December 67 40 107
2023 November 58 44 102
2023 October 71 47 118
2023 September 48 39 87
2023 August 53 41 94
2023 July 67 53 120
2023 June 57 40 97
2023 May 67 57 124
2023 April 53 25 78
2023 March 75 30 105
2023 February 64 34 98
2023 January 62 42 104
2022 December 104 48 152
2022 November 77 36 113
2022 October 78 64 142
2022 September 72 59 131
2022 August 78 59 137
2022 July 57 61 118
2022 June 77 61 138
2022 May 68 37 105
2022 April 66 65 131
2022 March 57 67 124
2022 February 73 59 132
2022 January 89 72 161
2021 December 93 53 146
2021 November 47 45 92
2021 October 144 76 220
2021 September 54 51 105
2021 August 53 58 111
2021 July 55 57 112
2021 June 32 40 72
2021 May 43 51 94
2021 April 101 102 203
2021 March 80 54 134
2021 February 56 58 114
2021 January 61 24 85
2020 December 49 18 67
2020 November 70 26 96
2020 October 49 32 81
2020 September 43 17 60
2020 August 72 26 98
2020 July 59 16 75
2020 June 54 29 83
2020 May 75 12 87
2020 April 62 24 86
2020 March 68 26 94
2020 February 63 18 81
2020 January 81 40 121
2019 December 69 37 106
2019 November 86 29 115
2019 October 54 16 70
2019 September 61 15 76
2019 August 69 25 94
2019 July 87 28 115
2019 June 57 33 90
2019 May 65 26 91
2019 April 91 49 140
2019 March 52 33 85
2019 February 31 33 64
2019 January 64 45 109
2018 December 198 40 238
2018 November 480 24 504
2018 October 378 20 398
2018 September 154 27 181
2018 August 115 23 138
2018 July 110 18 128
2018 June 86 13 99
2018 May 144 17 161
2018 April 216 13 229
2018 March 346 17 363
2018 February 69 7 76
2018 January 44 7 51
2017 December 33 5 38
Show all

Follow this link to access the full text of the article

Subscribe to our newsletter

Open access
This work is licensed under a Creative Commons Attribution 4.0 International License.
Creative Commons License
Publish in
Nefrología
NEFROLOGÍA
AL DÍA
Idiomas
Nefrología (English Edition)