array:25 [
  "pii" => "S2013251416000328"
  "issn" => "20132514"
  "doi" => "10.1016/j.nefroe.2016.03.002"
  "estado" => "S300"
  "fechaPublicacion" => "2016-01-01"
  "aid" => "115"
  "copyright" => "Sociedad Española de Nefrología"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Nefrologia (English Version). 2016;36:78-80"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4093
    "formatos" => array:3 [
      "EPUB" => 349
      "HTML" => 3123
      "PDF" => 621
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0211699515001678"
      "issn" => "02116995"
      "doi" => "10.1016/j.nefro.2015.07.012"
      "estado" => "S300"
      "fechaPublicacion" => "2016-01-01"
      "aid" => "115"
      "copyright" => "Sociedad Española de Nefrología"
      "documento" => "simple-article"
      "crossmark" => 0
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "cor"
      "cita" => "Nefrologia. 2016;36:78-80"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6372
        "formatos" => array:3 [
          "EPUB" => 417
          "HTML" => 5255
          "PDF" => 700
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "78"
            "paginaFinal" => "80"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Microscopic polyangiitis in a patient with primary biliary cirrhosis&#58; Treatment complications"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1427
                "Ancho" => 2248
                "Tamanyo" => 130592
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evoluci&#243;n de cifras de creatinina&#44; proteinuria y p-ANCA tras iniciar tratamiento con corticoides y ciclofosfamida&#46; La franja gris representa el periodo de ingreso en el servicio de nefrolog&#237;a&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Elena Ruiz-Ferreras, Alberto Mart&#237;n-Arribas, Guadalupe Tabernero-Fern&#225;ndez, Jos&#233; Luis Lerma-M&#225;rquez, Pilar Fraile-G&#243;mez, Pedro Garc&#237;a-Cosmes, Jos&#233; Mat&#237;as Tabernero-Romo"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "Elena"
                "apellidos" => "Ruiz-Ferreras"
              ]
              1 => array:2 [
                "nombre" => "Alberto"
                "apellidos" => "Mart&#237;n-Arribas"
              ]
              2 => array:2 [
                "nombre" => "Guadalupe"
                "apellidos" => "Tabernero-Fern&#225;ndez"
              ]
              3 => array:2 [
                "nombre" => "Jos&#233; Luis"
                "apellidos" => "Lerma-M&#225;rquez"
              ]
              4 => array:2 [
                "nombre" => "Pilar"
                "apellidos" => "Fraile-G&#243;mez"
              ]
              5 => array:2 [
                "nombre" => "Pedro"
                "apellidos" => "Garc&#237;a-Cosmes"
              ]
              6 => array:2 [
                "nombre" => "Jos&#233;"
                "apellidos" => "Mat&#237;as Tabernero-Romo"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2013251416000328"
          "doi" => "10.1016/j.nefroe.2016.03.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000328?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001678?idApp=UINPBA000064"
      "url" => "/02116995/0000003600000001/v1_201602110042/S0211699515001678/v1_201602110042/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2013251416000316"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2016.03.001"
    "estado" => "S300"
    "fechaPublicacion" => "2016-01-01"
    "aid" => "114"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia &#40;English Version&#41;. 2016;36:80-1"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3947
      "formatos" => array:3 [
        "EPUB" => 299
        "HTML" => 3062
        "PDF" => 586
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "An uncommon cause of spontaneous hemoperitoneum in a peritoneal dialysis patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "80"
          "paginaFinal" => "81"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Una causa infrecuente de hemoperitoneo espont&#225;neo en un paciente en di&#225;lisis peritoneal"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1627
              "Ancho" => 1495
              "Tamanyo" => 362110
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT imaging of a hyperdense nodule in the posterior region of the gastric fundus&#44; compatible with pseudoaneurysm of the left gastric artery&#44; with an underlying haematoma&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Carlos Hidalgo-Ordo&#241;ez, Emilio S&#225;nchez-Alvarez, Carmen Rodr&#237;guez-Su&#225;rez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Hidalgo-Ordo&#241;ez"
            ]
            1 => array:2 [
              "nombre" => "Emilio"
              "apellidos" => "S&#225;nchez-Alvarez"
            ]
            2 => array:2 [
              "nombre" => "Carmen"
              "apellidos" => "Rodr&#237;guez-Su&#225;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699515001666"
        "doi" => "10.1016/j.nefro.2015.08.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001666?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000316?idApp=UINPBA000064"
    "url" => "/20132514/0000003600000001/v2_201703300133/S2013251416000316/v2_201703300133/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S201325141600033X"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2016.03.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-01-01"
    "aid" => "126"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia &#40;English Version&#41;. 2016;36:76-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5519
      "formatos" => array:3 [
        "EPUB" => 335
        "HTML" => 4523
        "PDF" => 661
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Necrotizing glomerulonephritis in levamisole-contaminated cocaine use"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "76"
          "paginaFinal" => "78"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Glomerulonefritis necrosante en el s&#237;ndrome por consumo de coca&#237;na y levamisol"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 703
              "Ancho" => 975
              "Tamanyo" => 241484
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Glomerulus with segmental fibrinoid necrosis and fibrous half-moon &#40;SBP<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>40&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ana Esther Sirvent, Ricardo Enr&#237;quez, Encarnaci&#243;n Andrada, Mar&#237;a S&#225;nchez, Isabel Mill&#225;n, C&#233;sar Gonz&#225;lez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Ana Esther"
              "apellidos" => "Sirvent"
            ]
            1 => array:2 [
              "nombre" => "Ricardo"
              "apellidos" => "Enr&#237;quez"
            ]
            2 => array:2 [
              "nombre" => "Encarnaci&#243;n"
              "apellidos" => "Andrada"
            ]
            3 => array:2 [
              "nombre" => "Mar&#237;a"
              "apellidos" => "S&#225;nchez"
            ]
            4 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Mill&#225;n"
            ]
            5 => array:2 [
              "nombre" => "C&#233;sar"
              "apellidos" => "Gonz&#225;lez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699515001939"
        "doi" => "10.1016/j.nefro.2015.10.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001939?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S201325141600033X?idApp=UINPBA000064"
    "url" => "/20132514/0000003600000001/v2_201703300133/S201325141600033X/v2_201703300133/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Microscopic polyangiitis in a patient with primary biliary cirrhosis&#58; Treatment complications"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "78"
        "paginaFinal" => "80"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Elena Ruiz-Ferreras, Alberto Mart&#237;n-Arribas, Guadalupe Tabernero-Fern&#225;ndez, Jos&#233; Luis Lerma-M&#225;rquez, Pilar Fraile-G&#243;mez, Pedro Garc&#237;a-Cosmes, Jos&#233; Mat&#237;as Tabernero-Romo"
        "autores" => array:7 [
          0 => array:4 [
            "nombre" => "Elena"
            "apellidos" => "Ruiz-Ferreras"
            "email" => array:1 [
              0 => "eruiz&#95;burg&#64;hotmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Alberto"
            "apellidos" => "Mart&#237;n-Arribas"
          ]
          2 => array:2 [
            "nombre" => "Guadalupe"
            "apellidos" => "Tabernero-Fern&#225;ndez"
          ]
          3 => array:2 [
            "nombre" => "Jos&#233; Luis"
            "apellidos" => "Lerma-M&#225;rquez"
          ]
          4 => array:2 [
            "nombre" => "Pilar"
            "apellidos" => "Fraile-G&#243;mez"
          ]
          5 => array:2 [
            "nombre" => "Pedro"
            "apellidos" => "Garc&#237;a-Cosmes"
          ]
          6 => array:2 [
            "nombre" => "Jos&#233; Mat&#237;as"
            "apellidos" => "Tabernero-Romo"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Hospital Universitario de Salamanca&#44; Salamanca&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 780
            "Ancho" => 996
            "Tamanyo" => 97065
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Colonoscopy&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 70-year-old woman with a prior history of primary biliary cirrhosis diagnosed 18 months earlier&#44; being treated with ursodeoxycholic acid 600<span class="elsevierStyleHsp" style=""></span>mg&#47;day&#46; No prior history of hypertension or diabetes mellitus&#46; No known kidney diseases&#46; Admitted to the nephrology department owing to acute renal function deterioration &#40;creatinine&#58; 4&#46;12<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#59; urea&#58; 122<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#41;&#46; Reported wasting syndrome&#44; over a period of several months&#46; Diuresis was maintained&#44; and vital signs &#40;blood pressure &#91;BP&#93;&#58; 125&#47;75<span class="elsevierStyleHsp" style=""></span>mmHg&#41; and physical examination were normal&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Findings included normocytic normochromic anaemia &#40;Hb 10&#46;3<span class="elsevierStyleHsp" style=""></span>g&#47;dl&#41;&#44; which required initiation of erythropoietin treatment&#46; Proteinuria of 0&#46;840<span class="elsevierStyleHsp" style=""></span>g&#47;day with granular casts in the sediment&#44; and &#43;&#43;&#43;&#43; microhaematuria&#46; She tested positive for p-ANCAs at a titre of 29&#46;1<span class="elsevierStyleHsp" style=""></span>IU&#47;ml&#46; She also tested positive for anti-mitochondrial antibodies that were&#44; at stable levels&#44; given her already known biliary cirrhosis&#46; Considering her acute kidney failure with positive autoimmunity for p-ANCAs&#44; she underwent a kidney biopsy&#44; which was consistent with diffuse extracapillary proliferative glomerulonephritis with cellular crescents in 75&#37; of her glomeruli&#46; She was diagnosed with rapidly progressive kidney failure secondary to type <span class="elsevierStyleSmallCaps">III</span> or pauci-immune extracapillary proliferative glomerulonephritis&#44; consistent with microscopic polyangiitis &#40;MPA&#41;&#46; Treatment with corticosteroids and oral cyclophosphamide &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>mg&#47;kg&#47;day&#41; was indicated&#46; Good response to treatment with modest kidney improvement up to a creatinine level of 3&#46;63<span class="elsevierStyleHsp" style=""></span>mg&#47;dl at discharge from the hospital&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">During subsequent follow-up in a nephrology visit&#44; the patient was found to be asymptomatic and with a good control of BP&#46; Her serum creatinine values decreased &#40;1&#46;56<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#41;&#44; her p-ANCA titre were also reduced &#40;8&#46;5<span class="elsevierStyleHsp" style=""></span>IU&#47;ml&#41;&#44; her proteinuria decreased &#40;0&#46;639<span class="elsevierStyleHsp" style=""></span>g&#47;day&#41; and her microhaematuria disappeared &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; In addition&#44; her haemoglobin levels improved so erythropoietin treatment was discontinued&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Two months after hospital discharge&#44; she was admitted to the GI department due to gastrointestinal bleeding that affected her laboratory results with an acute exacerbation of renal failure due to hypotension and volume depletion&#46; Gastroscopy and a colonoscopy were performed&#59; denudation with capillary bleeding upon contact plus superficial and deep ulcers were observed&#44; thus signs of vasculitis and inflammatory bowel disease were ruled out&#46; As for infection&#44; she tested positive for IgMs for cytomegalovirus&#44; and herpes virus was isolated in oropharyngeal lesions&#46; Despite the improvement in renal function up to baseline levels&#44; the patient had a poor clinical course&#44; as frequent fresh bloody stools persisted and she required transfusions every 24&#8211;48<span class="elsevierStyleHsp" style=""></span>h that required admission to ICU&#46; A repeat colonoscopy was performed&#44; which showed multiple deep ulcers on punch biopsy with abundant bleeding &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; and CMV of 27&#44;784<span class="elsevierStyleHsp" style=""></span>cop&#47;ml was confirmed with PCR&#46; Anti-viral treatment with ganciclovir and aciclovir was administered&#46; A diagnosis was made of lower gastrointestinal bleeding secondary to enteritis due to cytomegalovirus in an immunosuppressed patient&#59; in addition patient had herpes virus together with haemorrhagic colitis due to direct cyclophosphamide toxicity with secondary thrombocytopenia&#46; Patient had uncontrollable gastrointestinal bleeding and despite a reasonable response of the kidney disease&#44; she died a month and a half after hospital admission&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">MPA is characterised by a constant and early presence of rapidly progressive glomerulonephritis&#46; It is important to bear in mind treatment-related complications due to both direct toxicity and immunosuppression-related toxicities&#46; In our patient&#39;s case&#44; although her kidney disease responded well to treatment&#44; there was a fatal complication&#44; cytomegalovirus enteritis&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">1&#44;2</span></a> This led to uncontrollable lower gastrointestinal bleeding and&#44; finally&#44; to her death&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">It is not uncommon to find a combination of several autoimmune diseases in a single patient&#44; given their common background&#46; In our case&#44; MPA was diagnosed in a patient with a prior history of primary biliary cirrhosis&#44; even though there are few references in the literature of cases in which these two diseases are combined&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">5&#8211;7</span></a></p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Ruiz-Ferreras E&#44; Mart&#237;n-Arribas A&#44; Tabernero-Fern&#225;ndez G&#44; Lerma-M&#225;rquez JL&#44; Fraile-G&#243;mez P&#44; Garc&#237;a-Cosmes P&#44; et al&#46; Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento&#46; Nefrolog&#237;a&#46; 2016&#59;36&#58;78&#8211;80&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1398
            "Ancho" => 2248
            "Tamanyo" => 128843
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evolution of creatinine&#44; proteinuria and p-ANCA figures after starting treatment with corticosteroids and cyclophosphamide&#46; The grey band represents the period of admission in the nephrology department&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 780
            "Ancho" => 996
            "Tamanyo" => 97065
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Colonoscopy&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case of granulomatosis with polyangiitis complicated by cyclophosphamide toxicity and opportunistic infections&#58; choosing between Scylla and Charybdis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Ernst"
                            1 => "M&#46; Girndt"
                            2 => "R&#46;U&#46; Pliquett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2369-15-28"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Nephrol"
                        "fecha" => "2014"
                        "volumen" => "15"
                        "paginaInicial" => "28"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24495297"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wegener&#39;s granulomatosis complicated by intestinal ulcer due to cytomegalovirus infection and by thrombotic thrombocytopenic purpura"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Yamazaki"
                            1 => "T&#46; Takei"
                            2 => "S&#46; Otsubo"
                            3 => "Y&#46; Iwasa"
                            4 => "Y&#46; Yabuki"
                            5 => "K&#46; Suzuki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Med"
                        "fecha" => "2007"
                        "volumen" => "46"
                        "paginaInicial" => "1435"
                        "paginaFinal" => "1440"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17827845"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "&#91;Article in Japanese&#93;&#46; Erratum in&#58; Nihon Rinsho Meneki Gakkai Kaishi 2010&#59;<span class="elsevierStyleBold">33</span>&#58;117&#46; Wakaura&#44; Daisuke &#91;corrected to Wakura&#44; Daisuke&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A refractory case of MPO-ANCA-associated vasculitis presented with gastrointestinal ulcer&#44; rapidly progressive glomerular nephritis and pulmonary multiple nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Wakura"
                            1 => "M&#46; Yoneda"
                            2 => "T&#46; Kotani"
                            3 => "Y&#46; Egashira"
                            4 => "K&#46; Nagai"
                            5 => "T&#46; Shoda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nihon Rinsho Meneki Gakkai Kaishi"
                        "fecha" => "2010"
                        "volumen" => "33"
                        "paginaInicial" => "31"
                        "paginaFinal" => "36"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20190508"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides&#58; analysis of 62 patients with polyarteritis nodosa&#44; microscopic polyangiitis&#44; Wegener granulomatosis&#44; Churg&#8211;Strauss syndrome&#44; or rheumatoid arthritis-associated vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Pagnoux"
                            1 => "A&#46; Mahr"
                            2 => "P&#46; Cohen"
                            3 => "L&#46; Guillevin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine &#40;Baltim&#41;"
                        "fecha" => "2005"
                        "volumen" => "84"
                        "paginaInicial" => "115"
                        "paginaFinal" => "128"
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109713060294"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Microscopic polyangiitis associated with primary biliary cirrhosis&#58; a causal or casual association&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46;M&#46; Amezcua-Guerra"
                            1 => "P&#46; Prieto"
                            2 => "R&#46; Bojalil"
                            3 => "C&#46; Pineda"
                            4 => "M&#46;C&#46; Amigo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2006"
                        "volumen" => "33"
                        "paginaInicial" => "2351"
                        "paginaFinal" => "2353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16981285"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Microscopic polyangiitis associated with primary biliary cirrhosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Iannone"
                            1 => "P&#46; Falappone"
                            2 => "G&#46; Pannarale"
                            3 => "A&#46; Gentile"
                            4 => "V&#46; Grattagliano"
                            5 => "M&#46; Covelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2003"
                        "volumen" => "30"
                        "paginaInicial" => "2710"
                        "paginaFinal" => "2712"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14719218"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antineutrophil cytoplasmic autoantibody associated rapidly progressive glomerulonephritis in a patient with primary biliary cirrhosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46; Nakamura"
                            1 => "Y&#46; Kawagoe"
                            2 => "Y&#46; Ueda"
                            3 => "H&#46; Koide"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med Sci"
                        "fecha" => "2004"
                        "volumen" => "328"
                        "paginaInicial" => "176"
                        "paginaFinal" => "179"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15367878"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003600000001/v2_201703300133/S2013251416000328/v2_201703300133/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35436"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003600000001/v2_201703300133/S2013251416000328/v2_201703300133/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000328?idApp=UINPBA000064"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Letter to the Editor
Microscopic polyangiitis in a patient with primary biliary cirrhosis: Treatment complications
Poliangeítis microscópica en paciente con cirrosis biliar primaria. Complicaciones del tratamiento
Elena Ruiz-Ferreras
Corresponding author
eruiz_burg@hotmail.com

Corresponding author.
, Alberto Martín-Arribas, Guadalupe Tabernero-Fernández, José Luis Lerma-Márquez, Pilar Fraile-Gómez, Pedro García-Cosmes, José Matías Tabernero-Romo
Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, Spain
Read
7818
Times
was read the article
2299
Total PDF
5519
Total HTML
Share statistics
 array:25 [
  "pii" => "S2013251416000328"
  "issn" => "20132514"
  "doi" => "10.1016/j.nefroe.2016.03.002"
  "estado" => "S300"
  "fechaPublicacion" => "2016-01-01"
  "aid" => "115"
  "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Nefrologia &#40;English Version&#41;. 2016;36:78-80"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4093
    "formatos" => array:3 [
      "EPUB" => 349
      "HTML" => 3123
      "PDF" => 621
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0211699515001678"
      "issn" => "02116995"
      "doi" => "10.1016/j.nefro.2015.07.012"
      "estado" => "S300"
      "fechaPublicacion" => "2016-01-01"
      "aid" => "115"
      "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
      "documento" => "simple-article"
      "crossmark" => 0
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "cor"
      "cita" => "Nefrologia. 2016;36:78-80"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 6372
        "formatos" => array:3 [
          "EPUB" => 417
          "HTML" => 5255
          "PDF" => 700
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "78"
            "paginaFinal" => "80"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Microscopic polyangiitis in a patient with primary biliary cirrhosis&#58; Treatment complications"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1427
                "Ancho" => 2248
                "Tamanyo" => 130592
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evoluci&#243;n de cifras de creatinina&#44; proteinuria y p-ANCA tras iniciar tratamiento con corticoides y ciclofosfamida&#46; La franja gris representa el periodo de ingreso en el servicio de nefrolog&#237;a&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Elena Ruiz-Ferreras, Alberto Mart&#237;n-Arribas, Guadalupe Tabernero-Fern&#225;ndez, Jos&#233; Luis Lerma-M&#225;rquez, Pilar Fraile-G&#243;mez, Pedro Garc&#237;a-Cosmes, Jos&#233; Mat&#237;as Tabernero-Romo"
            "autores" => array:7 [
              0 => array:2 [
                "nombre" => "Elena"
                "apellidos" => "Ruiz-Ferreras"
              ]
              1 => array:2 [
                "nombre" => "Alberto"
                "apellidos" => "Mart&#237;n-Arribas"
              ]
              2 => array:2 [
                "nombre" => "Guadalupe"
                "apellidos" => "Tabernero-Fern&#225;ndez"
              ]
              3 => array:2 [
                "nombre" => "Jos&#233; Luis"
                "apellidos" => "Lerma-M&#225;rquez"
              ]
              4 => array:2 [
                "nombre" => "Pilar"
                "apellidos" => "Fraile-G&#243;mez"
              ]
              5 => array:2 [
                "nombre" => "Pedro"
                "apellidos" => "Garc&#237;a-Cosmes"
              ]
              6 => array:2 [
                "nombre" => "Jos&#233;"
                "apellidos" => "Mat&#237;as Tabernero-Romo"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2013251416000328"
          "doi" => "10.1016/j.nefroe.2016.03.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000328?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001678?idApp=UINPBA000064"
      "url" => "/02116995/0000003600000001/v1_201602110042/S0211699515001678/v1_201602110042/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S2013251416000316"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2016.03.001"
    "estado" => "S300"
    "fechaPublicacion" => "2016-01-01"
    "aid" => "114"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia &#40;English Version&#41;. 2016;36:80-1"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3947
      "formatos" => array:3 [
        "EPUB" => 299
        "HTML" => 3062
        "PDF" => 586
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "An uncommon cause of spontaneous hemoperitoneum in a peritoneal dialysis patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "80"
          "paginaFinal" => "81"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Una causa infrecuente de hemoperitoneo espont&#225;neo en un paciente en di&#225;lisis peritoneal"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1627
              "Ancho" => 1495
              "Tamanyo" => 362110
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT imaging of a hyperdense nodule in the posterior region of the gastric fundus&#44; compatible with pseudoaneurysm of the left gastric artery&#44; with an underlying haematoma&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Carlos Hidalgo-Ordo&#241;ez, Emilio S&#225;nchez-Alvarez, Carmen Rodr&#237;guez-Su&#225;rez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Carlos"
              "apellidos" => "Hidalgo-Ordo&#241;ez"
            ]
            1 => array:2 [
              "nombre" => "Emilio"
              "apellidos" => "S&#225;nchez-Alvarez"
            ]
            2 => array:2 [
              "nombre" => "Carmen"
              "apellidos" => "Rodr&#237;guez-Su&#225;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699515001666"
        "doi" => "10.1016/j.nefro.2015.08.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001666?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000316?idApp=UINPBA000064"
    "url" => "/20132514/0000003600000001/v2_201703300133/S2013251416000316/v2_201703300133/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S201325141600033X"
    "issn" => "20132514"
    "doi" => "10.1016/j.nefroe.2016.03.003"
    "estado" => "S300"
    "fechaPublicacion" => "2016-01-01"
    "aid" => "126"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia &#40;English Version&#41;. 2016;36:76-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5519
      "formatos" => array:3 [
        "EPUB" => 335
        "HTML" => 4523
        "PDF" => 661
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Necrotizing glomerulonephritis in levamisole-contaminated cocaine use"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "76"
          "paginaFinal" => "78"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Glomerulonefritis necrosante en el s&#237;ndrome por consumo de coca&#237;na y levamisol"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 703
              "Ancho" => 975
              "Tamanyo" => 241484
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Glomerulus with segmental fibrinoid necrosis and fibrous half-moon &#40;SBP<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>40&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ana Esther Sirvent, Ricardo Enr&#237;quez, Encarnaci&#243;n Andrada, Mar&#237;a S&#225;nchez, Isabel Mill&#225;n, C&#233;sar Gonz&#225;lez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Ana Esther"
              "apellidos" => "Sirvent"
            ]
            1 => array:2 [
              "nombre" => "Ricardo"
              "apellidos" => "Enr&#237;quez"
            ]
            2 => array:2 [
              "nombre" => "Encarnaci&#243;n"
              "apellidos" => "Andrada"
            ]
            3 => array:2 [
              "nombre" => "Mar&#237;a"
              "apellidos" => "S&#225;nchez"
            ]
            4 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Mill&#225;n"
            ]
            5 => array:2 [
              "nombre" => "C&#233;sar"
              "apellidos" => "Gonz&#225;lez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0211699515001939"
        "doi" => "10.1016/j.nefro.2015.10.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001939?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S201325141600033X?idApp=UINPBA000064"
    "url" => "/20132514/0000003600000001/v2_201703300133/S201325141600033X/v2_201703300133/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Microscopic polyangiitis in a patient with primary biliary cirrhosis&#58; Treatment complications"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "78"
        "paginaFinal" => "80"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Elena Ruiz-Ferreras, Alberto Mart&#237;n-Arribas, Guadalupe Tabernero-Fern&#225;ndez, Jos&#233; Luis Lerma-M&#225;rquez, Pilar Fraile-G&#243;mez, Pedro Garc&#237;a-Cosmes, Jos&#233; Mat&#237;as Tabernero-Romo"
        "autores" => array:7 [
          0 => array:4 [
            "nombre" => "Elena"
            "apellidos" => "Ruiz-Ferreras"
            "email" => array:1 [
              0 => "eruiz&#95;burg&#64;hotmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Alberto"
            "apellidos" => "Mart&#237;n-Arribas"
          ]
          2 => array:2 [
            "nombre" => "Guadalupe"
            "apellidos" => "Tabernero-Fern&#225;ndez"
          ]
          3 => array:2 [
            "nombre" => "Jos&#233; Luis"
            "apellidos" => "Lerma-M&#225;rquez"
          ]
          4 => array:2 [
            "nombre" => "Pilar"
            "apellidos" => "Fraile-G&#243;mez"
          ]
          5 => array:2 [
            "nombre" => "Pedro"
            "apellidos" => "Garc&#237;a-Cosmes"
          ]
          6 => array:2 [
            "nombre" => "Jos&#233; Mat&#237;as"
            "apellidos" => "Tabernero-Romo"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Nefrolog&#237;a&#44; Hospital Universitario de Salamanca&#44; Salamanca&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 780
            "Ancho" => 996
            "Tamanyo" => 97065
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Colonoscopy&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 70-year-old woman with a prior history of primary biliary cirrhosis diagnosed 18 months earlier&#44; being treated with ursodeoxycholic acid 600<span class="elsevierStyleHsp" style=""></span>mg&#47;day&#46; No prior history of hypertension or diabetes mellitus&#46; No known kidney diseases&#46; Admitted to the nephrology department owing to acute renal function deterioration &#40;creatinine&#58; 4&#46;12<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#59; urea&#58; 122<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#41;&#46; Reported wasting syndrome&#44; over a period of several months&#46; Diuresis was maintained&#44; and vital signs &#40;blood pressure &#91;BP&#93;&#58; 125&#47;75<span class="elsevierStyleHsp" style=""></span>mmHg&#41; and physical examination were normal&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Findings included normocytic normochromic anaemia &#40;Hb 10&#46;3<span class="elsevierStyleHsp" style=""></span>g&#47;dl&#41;&#44; which required initiation of erythropoietin treatment&#46; Proteinuria of 0&#46;840<span class="elsevierStyleHsp" style=""></span>g&#47;day with granular casts in the sediment&#44; and &#43;&#43;&#43;&#43; microhaematuria&#46; She tested positive for p-ANCAs at a titre of 29&#46;1<span class="elsevierStyleHsp" style=""></span>IU&#47;ml&#46; She also tested positive for anti-mitochondrial antibodies that were&#44; at stable levels&#44; given her already known biliary cirrhosis&#46; Considering her acute kidney failure with positive autoimmunity for p-ANCAs&#44; she underwent a kidney biopsy&#44; which was consistent with diffuse extracapillary proliferative glomerulonephritis with cellular crescents in 75&#37; of her glomeruli&#46; She was diagnosed with rapidly progressive kidney failure secondary to type <span class="elsevierStyleSmallCaps">III</span> or pauci-immune extracapillary proliferative glomerulonephritis&#44; consistent with microscopic polyangiitis &#40;MPA&#41;&#46; Treatment with corticosteroids and oral cyclophosphamide &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>mg&#47;kg&#47;day&#41; was indicated&#46; Good response to treatment with modest kidney improvement up to a creatinine level of 3&#46;63<span class="elsevierStyleHsp" style=""></span>mg&#47;dl at discharge from the hospital&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">During subsequent follow-up in a nephrology visit&#44; the patient was found to be asymptomatic and with a good control of BP&#46; Her serum creatinine values decreased &#40;1&#46;56<span class="elsevierStyleHsp" style=""></span>mg&#47;dl&#41;&#44; her p-ANCA titre were also reduced &#40;8&#46;5<span class="elsevierStyleHsp" style=""></span>IU&#47;ml&#41;&#44; her proteinuria decreased &#40;0&#46;639<span class="elsevierStyleHsp" style=""></span>g&#47;day&#41; and her microhaematuria disappeared &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; In addition&#44; her haemoglobin levels improved so erythropoietin treatment was discontinued&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Two months after hospital discharge&#44; she was admitted to the GI department due to gastrointestinal bleeding that affected her laboratory results with an acute exacerbation of renal failure due to hypotension and volume depletion&#46; Gastroscopy and a colonoscopy were performed&#59; denudation with capillary bleeding upon contact plus superficial and deep ulcers were observed&#44; thus signs of vasculitis and inflammatory bowel disease were ruled out&#46; As for infection&#44; she tested positive for IgMs for cytomegalovirus&#44; and herpes virus was isolated in oropharyngeal lesions&#46; Despite the improvement in renal function up to baseline levels&#44; the patient had a poor clinical course&#44; as frequent fresh bloody stools persisted and she required transfusions every 24&#8211;48<span class="elsevierStyleHsp" style=""></span>h that required admission to ICU&#46; A repeat colonoscopy was performed&#44; which showed multiple deep ulcers on punch biopsy with abundant bleeding &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; and CMV of 27&#44;784<span class="elsevierStyleHsp" style=""></span>cop&#47;ml was confirmed with PCR&#46; Anti-viral treatment with ganciclovir and aciclovir was administered&#46; A diagnosis was made of lower gastrointestinal bleeding secondary to enteritis due to cytomegalovirus in an immunosuppressed patient&#59; in addition patient had herpes virus together with haemorrhagic colitis due to direct cyclophosphamide toxicity with secondary thrombocytopenia&#46; Patient had uncontrollable gastrointestinal bleeding and despite a reasonable response of the kidney disease&#44; she died a month and a half after hospital admission&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">MPA is characterised by a constant and early presence of rapidly progressive glomerulonephritis&#46; It is important to bear in mind treatment-related complications due to both direct toxicity and immunosuppression-related toxicities&#46; In our patient&#39;s case&#44; although her kidney disease responded well to treatment&#44; there was a fatal complication&#44; cytomegalovirus enteritis&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">1&#44;2</span></a> This led to uncontrollable lower gastrointestinal bleeding and&#44; finally&#44; to her death&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">It is not uncommon to find a combination of several autoimmune diseases in a single patient&#44; given their common background&#46; In our case&#44; MPA was diagnosed in a patient with a prior history of primary biliary cirrhosis&#44; even though there are few references in the literature of cases in which these two diseases are combined&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">5&#8211;7</span></a></p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Ruiz-Ferreras E&#44; Mart&#237;n-Arribas A&#44; Tabernero-Fern&#225;ndez G&#44; Lerma-M&#225;rquez JL&#44; Fraile-G&#243;mez P&#44; Garc&#237;a-Cosmes P&#44; et al&#46; Poliange&#237;tis microsc&#243;pica en paciente con cirrosis biliar primaria&#46; Complicaciones del tratamiento&#46; Nefrolog&#237;a&#46; 2016&#59;36&#58;78&#8211;80&#46;</p>"
      ]
    ]
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1398
            "Ancho" => 2248
            "Tamanyo" => 128843
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evolution of creatinine&#44; proteinuria and p-ANCA figures after starting treatment with corticosteroids and cyclophosphamide&#46; The grey band represents the period of admission in the nephrology department&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 780
            "Ancho" => 996
            "Tamanyo" => 97065
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Colonoscopy&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case of granulomatosis with polyangiitis complicated by cyclophosphamide toxicity and opportunistic infections&#58; choosing between Scylla and Charybdis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Ernst"
                            1 => "M&#46; Girndt"
                            2 => "R&#46;U&#46; Pliquett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2369-15-28"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Nephrol"
                        "fecha" => "2014"
                        "volumen" => "15"
                        "paginaInicial" => "28"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24495297"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wegener&#39;s granulomatosis complicated by intestinal ulcer due to cytomegalovirus infection and by thrombotic thrombocytopenic purpura"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Yamazaki"
                            1 => "T&#46; Takei"
                            2 => "S&#46; Otsubo"
                            3 => "Y&#46; Iwasa"
                            4 => "Y&#46; Yabuki"
                            5 => "K&#46; Suzuki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Med"
                        "fecha" => "2007"
                        "volumen" => "46"
                        "paginaInicial" => "1435"
                        "paginaFinal" => "1440"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17827845"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "&#91;Article in Japanese&#93;&#46; Erratum in&#58; Nihon Rinsho Meneki Gakkai Kaishi 2010&#59;<span class="elsevierStyleBold">33</span>&#58;117&#46; Wakaura&#44; Daisuke &#91;corrected to Wakura&#44; Daisuke&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A refractory case of MPO-ANCA-associated vasculitis presented with gastrointestinal ulcer&#44; rapidly progressive glomerular nephritis and pulmonary multiple nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Wakura"
                            1 => "M&#46; Yoneda"
                            2 => "T&#46; Kotani"
                            3 => "Y&#46; Egashira"
                            4 => "K&#46; Nagai"
                            5 => "T&#46; Shoda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nihon Rinsho Meneki Gakkai Kaishi"
                        "fecha" => "2010"
                        "volumen" => "33"
                        "paginaInicial" => "31"
                        "paginaFinal" => "36"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20190508"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides&#58; analysis of 62 patients with polyarteritis nodosa&#44; microscopic polyangiitis&#44; Wegener granulomatosis&#44; Churg&#8211;Strauss syndrome&#44; or rheumatoid arthritis-associated vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Pagnoux"
                            1 => "A&#46; Mahr"
                            2 => "P&#46; Cohen"
                            3 => "L&#46; Guillevin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine &#40;Baltim&#41;"
                        "fecha" => "2005"
                        "volumen" => "84"
                        "paginaInicial" => "115"
                        "paginaFinal" => "128"
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109713060294"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Microscopic polyangiitis associated with primary biliary cirrhosis&#58; a causal or casual association&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46;M&#46; Amezcua-Guerra"
                            1 => "P&#46; Prieto"
                            2 => "R&#46; Bojalil"
                            3 => "C&#46; Pineda"
                            4 => "M&#46;C&#46; Amigo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2006"
                        "volumen" => "33"
                        "paginaInicial" => "2351"
                        "paginaFinal" => "2353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16981285"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Microscopic polyangiitis associated with primary biliary cirrhosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Iannone"
                            1 => "P&#46; Falappone"
                            2 => "G&#46; Pannarale"
                            3 => "A&#46; Gentile"
                            4 => "V&#46; Grattagliano"
                            5 => "M&#46; Covelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2003"
                        "volumen" => "30"
                        "paginaInicial" => "2710"
                        "paginaFinal" => "2712"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14719218"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antineutrophil cytoplasmic autoantibody associated rapidly progressive glomerulonephritis in a patient with primary biliary cirrhosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46; Nakamura"
                            1 => "Y&#46; Kawagoe"
                            2 => "Y&#46; Ueda"
                            3 => "H&#46; Koide"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med Sci"
                        "fecha" => "2004"
                        "volumen" => "328"
                        "paginaInicial" => "176"
                        "paginaFinal" => "179"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15367878"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000003600000001/v2_201703300133/S2013251416000328/v2_201703300133/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35436"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000003600000001/v2_201703300133/S2013251416000328/v2_201703300133/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000328?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 9 6 15
2024 October 41 48 89
2024 September 37 26 63
2024 August 49 47 96
2024 July 32 26 58
2024 June 49 35 84
2024 May 58 33 91
2024 April 50 32 82
2024 March 31 27 58
2024 February 41 38 79
2024 January 31 27 58
2023 December 22 26 48
2023 November 32 31 63
2023 October 31 36 67
2023 September 22 23 45
2023 August 35 31 66
2023 July 40 22 62
2023 June 35 20 55
2023 May 33 43 76
2023 April 17 17 34
2023 March 34 23 57
2023 February 26 13 39
2023 January 30 27 57
2022 December 52 34 86
2022 November 42 36 78
2022 October 48 39 87
2022 September 53 33 86
2022 August 53 41 94
2022 July 33 40 73
2022 June 35 34 69
2022 May 48 29 77
2022 April 64 52 116
2022 March 38 49 87
2022 February 67 40 107
2022 January 59 31 90
2021 December 32 39 71
2021 November 39 38 77
2021 October 81 42 123
2021 September 35 26 61
2021 August 44 34 78
2021 July 50 34 84
2021 June 67 21 88
2021 May 52 45 97
2021 April 90 24 114
2021 March 70 30 100
2021 February 45 36 81
2021 January 39 20 59
2020 December 44 26 70
2020 November 42 22 64
2020 October 35 23 58
2020 September 29 11 40
2020 August 39 7 46
2020 July 37 14 51
2020 June 38 10 48
2020 May 36 9 45
2020 April 37 27 64
2020 March 20 10 30
2020 February 37 25 62
2020 January 41 17 58
2019 December 42 29 71
2019 November 38 12 50
2019 October 17 12 29
2019 September 29 12 41
2019 August 22 17 39
2019 July 22 23 45
2019 June 32 11 43
2019 May 37 26 63
2019 April 74 29 103
2019 March 39 25 64
2019 February 23 18 41
2019 January 37 20 57
2018 December 129 38 167
2018 November 178 18 196
2018 October 171 32 203
2018 September 94 17 111
2018 August 68 17 85
2018 July 84 12 96
2018 June 96 20 116
2018 May 87 9 96
2018 April 136 15 151
2018 March 119 7 126
2018 February 104 7 111
2018 January 101 5 106
2017 December 96 6 102
2017 November 77 18 95
2017 October 42 8 50
2017 September 35 11 46
2017 August 26 11 37
2017 July 36 10 46
2017 June 41 17 58
2017 May 35 13 48
2017 April 40 10 50
2017 March 25 5 30
2017 February 44 7 51
2017 January 13 9 22
2016 December 29 7 36
2016 November 59 13 72
2016 October 69 3 72
2016 September 94 2 96
2016 August 70 2 72
2016 July 149 11 160
2016 June 110 0 110
2016 May 122 0 122
2016 April 72 0 72
Show all

Follow this link to access the full text of the article

Idiomas
Nefrología (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?