Journal Information
Vol. 33. Issue. 4.July 2013
Pages 443-622
Vol. 33. Issue. 4.July 2013
Pages 443-622
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Costos y resultados del tratamiento endovascular de las trombosis en las fístulas autólogas para hemodiálisis
Costs and outcomes of endovascular treatment of thrombosed dialysis autogenous fistulae
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Luis Coentraoa
a Nephrology Research and Development Unit, Sao Joao Hospital Centre, Porto, Portugal,
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El acceso vascular funcional es un requisito previo para el tratamiento renal sustitutivo en pacientes con enfermedad renal crónica. Las fístulas autólogas se consideran superiores a las prótesis vasculares y los catéteres venosos centrales; sin embargo, las fístulas no están exentas de problemas. Las trombosis de la fístula autóloga se han convertido en un reto en la práctica clínica de nefrología, con importantes implicaciones clínicas para pacientes en diálisis. Varios estudios han informado sobre la viabilidad y la tasa relativamente alta del éxito clínico del abordaje endovascular de fístulas trombosadas en los últimos años. Sin embargo, como las repetidas intervenciones suelen ser necesarias para lograr la supervivencia a largo plazo del acceso, el mantenimiento de una fístula anteriormente trombosada podría ser una política muy cara. Los objetivos de este artículo son proporcionar al lector una idea de los múltiples enfoques endovasculares para fístulas autólogas trombosadas, teniendo en cuenta su eficacia clínica y las implicaciones financieras.

Palabras clave:
Análisis de costo
Palabras clave:
Análisis económico
Palabras clave:
Fístula arteriovenosa autóloga
Palabras clave:
Trombectomía percutánea
Palabras clave:
Diálisis
Palabras clave:
Tratamiento endovascular

Functional vascular access is a prerequisite for adequate haemodialysis treatment in patients with end-stage renal disease. Autogenous arteriovenous fistulae are considered superior to synthetic grafts and central venous catheters; however, fistulae are not without problems. Fistulae thrombosis has become a clinical challenge in nephrology practice, with relevant clinical implications for dialysis patients. Several studies have reported on the feasibility and relatively high-clinical success rate of the endovascular approach to thrombosed fistulae in recent years. However, as repeated interventions are usually required to achieve long-term access survival, maintenance of a previously thrombosed fistulae could be a highly expensive policy. The goals of this article are to provide the reader an insight into the multiple endovascular approaches for thrombosed arteriovenous fistulae, bearing in mind its clinical effectiveness and financial implications.

Keywords:
Cost analysis
Keywords:
Economic analysis
Keywords:
Autogenous arteriovenous fistulae
Keywords:
Percutaneous thrombectomy
Keywords:
Dialysis
Keywords:
Endovascular treatment
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Bibliografía
[1]
Tordoir J, Canaud B, Haage P, Konner K, Basci A, Fouque D, et al. EBPG on vascular access. Nephrol Dial Transplant 2007;22 Suppl 2:ii88-ii117.
[2]
Vascular Access 2006 Work Group. KDOQI: Clinical practice guidelines and clinical practice recommendations for vascular access. Am J Kidney Dis 2006;48: S176-S247. [Pubmed]
[3]
SwanTL, Smyth SH, Ruffenbach SJ, Berman SS, Pond GD. Pulmonary embolism following hemodialysis access thrombolysis/thrombectomy. J Vasc Interv Radiol 1995;6:683-6. [Pubmed]
[4]
Trerotola SO, Johnson MS, Schauwecker DS, Davidson DD, Filo RS, Zhou XH, et al. Pulmonary emboli from pulse-spray and mechanical thrombolysis: evaluation with an animal diaysis-graft model. Radiology 1996;200:169-76. [Pubmed]
[5]
Miller GA, Hwang W, Preddie D, Khariton A, Savransky Y. Percutaneous salvage of thrombosed immature arteriovenous fistulas. Semin Dial 2011;24:107-14. [Pubmed]
[6]
Valji K, Bookstein JJ, Roberts AC, Oglevie SB, Pittman C, O'Neill MP. Pulse-spray pharmacomechanical thrombolysis of thrombosed hemodialysis access grafts: comparison of original and current techniques. AJR Am J Roentgenol 1995;165:1495-500.
[7]
Beathard GA, Welch BR, Maidment HJ. Mechanical thrombolysis for the treatment of thrombosed hemodialysis grafts. Radiology 1996;200:711-6. [Pubmed]
[8]
Trerotola SO, Vesely TM, Lung GB, Soulen MC, Ehrman KO, Cardella JF. Treatment of thrombosed hemodialysis access grafts: Arrow-Trerotola percutaneous thrombolytic device versus pulse-spray thrombolysis. Radiology 1998;206:403-14. [Pubmed]
[9]
Vorwerk D, Schurmann K, Müller-Leisse C, Adam G, Bücker A, Sohn M, et al. Hemodynamic thrombectomy of haemodialysis grafts and fistulae: results of 51 procedures. Nephrol Dial Transplant 1996;11:1058-64. [Pubmed]
[10]
Uflacker R, Rajagopalan PR, Vujic I, Stutley JE. Treatment of thombosed dialysis access grafts: randomized trial of surgical thrombectomy versus mechanical thrombectomy with the amplatz device. J Vasc  Interv Radiol 1996;7:185-92. [Pubmed]
[11]
Vesely TM, Williams D, Weiss M, Hicks M, Stainken B, Matalon T, et al. Comparison of the AngioJet rheolytic catheter to surgical thrombectomy for the treatment of thrombosed hemodialysis grafts. J Vasc Interv Radiol 1999;10:1195-205. [Pubmed]
[12]
Turmel-Rodrigues L, Sapoval M, Pengloan J, Billaux L, Testou D, Hauss S, et al. Manual thromboaspiration and dilation of thrombosed dialysis access: Mid-term results of a simple concept. J Vasc Interv Radiol 1997;8:813-24. [Pubmed]
[13]
Turmel-Rodrigues L, Pengloan J, Rodrigue H, Brillet G, Lataste A, Pierre D, et al. Treatment of failed native arteriovenous fistulae for hemodialysis by interventional radiology. Kidney Int 2000;57:1124-40. [Pubmed]
[14]
Moossavi S, Regan JD, Pierson ED, Kasey JM, Tuttle AB, Vachharajani TJ, et al. Nonsurgical salvage of thrombosed arterio-venous fistulae: A case series and review of the literature. Semin Dial 2007;20:459-64. [Pubmed]
[15]
Haage P, Vorwerk D, Wilberger JE, Piroth W, Schürmann K, Günther RW. Percutaneous treatment of thrombosed primary arteriovenous hemodialysis access fistulae. Kidney Int 2000;57:1169-75. [Pubmed]
[16]
Liang HL, Pan HB, Chung HM, Ger LP, Fang HC, Wu TH, et al. Restoration of thrombosed Brescia-Cimino dialysis fistulas by using percutaneous transluminal angioplasty. Radiology 2002;223:339-44. [Pubmed]
[17]
Rajan DK, Clark TW, Simons ME, Kachura JR, Sniderman K. Procedural success and patency after percutaneous treatment of thrombosed autogenous arteriovenous dialysis fistulas. J Vasc Interv Radiol 2002;13:1211-8. [Pubmed]
[18]
Shatsky JB, Berns JS, Clark TW, Kwak A, Tuite CM, Shlansky-Goldberg RD, et al. Single-center experience with the Arrow-Trerotola Percutaneous Thrombectomy device in the management of thrombosed native dialysis fistulas. J Vasc Interv Radiol 2005;16:1605-11. [Pubmed]
[19]
Jain G, Maya ID, Allon M. Outcomes of percutaneous mechanical thrombectomy of arteriovenous fistulas in hemodialysis patients. Semin Dial 2008;21:581-3. [Pubmed]
[20]
Vorwerk D, Konner K, Schürmann K, Günther RW. A simple trick to facilitate bleeding control after percutaneous hemodialysis fistula and graft interventions. Cardiovasc Intervent Radiol 1997;20:159-60. [Pubmed]
[21]
Klimas VA, Denny KM, Paganini EP, Graor RA, Nakamoto S, Risius B, et al. Low dose streptokinase therapy for thrombosed arteriovenous fistulas. Trans Am Soc Artif Intern Organs 1984;30:511-3. [Pubmed]
[22]
Zaleski GX, Funaki B, Kenney S, Lorenz JM, Garofalo R. Angioplasty and bolus urokinase infusion for the restoration of function in thrombosed Brescia-Cimino dialysis fistulas. J Vasc Interv Radiol 1999;10:129-36. [Pubmed]
[23]
Trerotola SO, Lund GB, Scheel PJ Jr, Savader SJ, Venbrux AC, Osterman FA Jr. Thrombosed dialysis access grafts: percutaneous mechanical declotting without urokinase. Radiology 1994;191:721-6. [Pubmed]
[24]
Trerotola SO, McLennan G, Davidson D, Lane KA, Ambrosius WT, Lazzaro C, et al. Preclinical in vivo testing of the Arrow-Trerotola percutaneous thrombolytic device for venous thrombosis. J Vasc Interv Radiol 2001;12:95-103. [Pubmed]
[25]
Rocek M, Peregrin JH, Lasovicková J, Krajícková D, Slavíoková M. Mechanical thrombolysis of thrombosed hemodialysis native fistulas with use of the Arrow-Trerotola percutaneous thrombolytic device: our preliminary experience. J Vasc Interv Radiol 2000;11:1153-8. [Pubmed]
[26]
Schmitz-Rode T, Wildberger JE, Hübner D, Wein B, Schürmann K, Günther RW. Recanalization of thrombosed dialysis access with use of a rotating mini-pigtail catheter: follow-up study. J Vasc Interv Radiol 2000;11:721-7. [Pubmed]
[27]
Sahni V, Kaniyur S, Malhotra A, Fan S, Blakeney C, Fotheringham T, et al. Mechanical thrombectomy of occluded hemodialysis native fistulas and grafts using a hydrodynamic thrombectomy catheter: preliminary experience. Cardiovasc Intervent Radiol 2005;28:714-21. [Pubmed]
[28]
Vorwerk D, Schurmann K, Müller-Leisse C, Adam G, Bücker A, Sohn M, et al. Hydrodynamic thrombectomy of haemodialysis grafts and fistulae: results of 51 procedures. Nephrol Dial Transplant 1996;11:1058-64. [Pubmed]
[29]
Overbosch EH, Pattynama PM, Aarts HJ, Schultze Kool LJ, Hermans J, Reekers JA. Occluded hemodialysis shunts: Dutch multicenter experience with the hydrolyser catheter. Radiology 1996;201:485-8. [Pubmed]
[30]
Rousseau H, Sapoval M, Ballini P, Dube M, Joffre F, Gaux JC, et al. Percutaneous recanalization of acutely thrombosed vessels by hydrodynamic thrombectomy (Hydrolyser). Eur Radiol 1997;7:935-41. [Pubmed]
[31]
Littler P, Cullen N, Gould D, Bakran A, Powell S. AngioJet thrombectomy for occluded dialysis fistulae: outcome data. Cardiovasc Intervent Radiol 2009;32:265-70. [Pubmed]
[32]
García Medina J, Lacasa Pérez N, Muray Cases S, Pérez Garrido I, García Medina V. Accesos vasculares para hemodiálisis trombosados: rescate mediante técnicas de radiología vascular intervencionista. Nefrologia 2009;29:249-55. [Pubmed]
[33]
Yang CC, Yang CW, Wen SC, Wu CC. Comparisons of clinical outcomes for thrombectomy devices with different mechanisms in hemodialysis arteriovenous fistulas. Catheter Cardiovasc Interv 2012;80(6):1035-41. [Pubmed]
[34]
Bizarro P, Coentrão L, Ribeiro C, Neto R, Pestana M. Endovascular treatment of thrombosed dialysis fistulae: a cumulative cost analysis. Catheter Cardiovasc Interv. 2011;77:1065-1070. [Pubmed]
[35]
Tordoir JH, Bode AS, Peppelenbosch N, van der Sande FM, de Haan MW. Surgical or endovascular repair of thrombosed dialysis vascular access: Is there any evidence? J Vasc Surg 2009;50:953-6. [Pubmed]
[36]
Ponikvar R. Surgical salvage of thrombosed arteriovenous fistulas and grafts. Ther Apher Dial 2005;9:245-9. [Pubmed]
[37]
Lipari G, Tessitore N, Poli A, Bedogna V, Impedovo A, Lupo A, et al. Outcomes of surgical revision of stenosed and thrombosed forearm arteriovenous fistulae for haemodialysis. Nephrol Dial Transplant 2007;22:2605-12. [Pubmed]
[38]
Beathard GA, Urbanes A, Litchfield A. The classification of procedure related complications-a fresh approach. Semin Dial 2006;19:527-34. [Pubmed]
[39]
Renaud CJ, Lopes K, Bourquelot P, Turmel-Rodrigues L. Skin and venous rupture at a hemodialysis needle cannulation site during angioplasty of a transposed forearm fistula. J Vasc Interv Radiol  2011;22:1488-9. [Pubmed]
[40]
Dolmatch BL, Gray RJ, Horton KM. Will iatrogenic pulmonary embolization be our pulmonary embarrassment? Radiology 1994;191:615-7.
[41]
Swan TL, Smyth SH, Ruffenach SJ, Berman SS, Pond GD. Pulmonary embolism following hemodialysis access thrombolysis/thrombectomy. J Vasc Interv Radiol 1995;6:683-86.
[42]
Valji K. Transcatheter treatment of thrombosed hemodialysis access grafts. AJR Am J Roentgenol 1995;164:823-9. [Pubmed]
[43]
USRDS: The economic cost of ESRD, vascular access procedures, and medicare spending for alternative modalities of treatment. Am J Kidney Dis 1997;30:S160-S177. [Pubmed]
[44]
Amedia CA Jr, Bolton WK, Cordray T, Hakim R, Howard R, Jackson J, et al. Vascular access for HD: aligning payment with quality. Semin Dial 2011;24:37-40. [Pubmed]
[45]
Tessitore N, Bedogna V, Poli A, Mantovani W, Lipari G, Baggio E, et al. Adding access blood flow surveillance to clinical monitoring reduces thrombosis rates and costs, and improves fistula patency in the short term: A controlled cohort study. Nephrol Dial Transplant 2008;23:3578-84. [Pubmed]
[46]
McCarley P, Wingard RL, Shyr Y, Pettus W, Hakim RM, Ikizler TA. Vascular access blood flow monitoring reduces access morbidity and costs. Kidney Int 2001;60:1164-72. [Pubmed]
[47]
Wijnen E, Planken N, Keuter X, Kooman JP, Tordoir JH, de Haan MW, et al. Impact of a quality improvement programme based on vascular access flow monitoring on costs, access occlusion and access failure. Nephrol Dial Transplant 2006;21:3514-9. [Pubmed]
[48]
Bittl JA, Cohen DJ, Seek MM, Feldman RL. Economic analysis of angiography and preemptive angioplasty to prevent hemodialysis access thrombosis. Catheter Cardiovasc Interv 2010;75:14-21. [Pubmed]
[49]
Sands JJ, Patel S, Plaviak DJ, Miranda CL. Pharmacomechanical thrombolysis with urokinase for treatment of thrombosed hemodialysis access grafts. ASAIO J 1994;40:M886-M888. [Pubmed]
[50]
Vesely TM, Idso MC, Audrain J, Windus DW, Lowell JA, et al. Thrombolysis versus surgical thrombectomy for the treatment of dialysis graft thrombosis: Pilot study comparing costs. J Vasc Interv Radiol 1996;7:507-12. [Pubmed]
[51]
Dougherty MJ, Calligaro KD, Schindler N, Raviola CA, Ntoso A. Endovascular versus surgical treatment for thrombosed hemodialysis grafts: A prospective, randomized study. J Vasc Surg 1999;30:1016-23. [Pubmed]
[52]
World Bank: World Development Indicators 2000. Washington DC: World Bank; 2001.
[53]
Coentrão L, Bizarro P, Ribeiro C, Neto R, Pestana M. Percutaneous treatment of thrombosed arteriovenous fistulas: clinical and economic implications. Clin J Am Soc Nephrol 2010;5:2245-50. [Pubmed]
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