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Disfunción sexual en pacientes en diálisis peritoneal: relación con factores metabólicos y con la percepción de la calidad de vida
Sexual dysfunction in men and women on peritoneal dialysis: Differential link with metabolic factors and quality of life perception
Pedro Azevedoa, Ricardo Santosb, José Durãesa, Olívia Santosc, Maria J. Carvalhoa, António Cabritaa, Anabela Rodriguesa
a Department of Nephrology and Renal Transplantation, Centro Hospitalar do Porto (CHP-HSA), Oporto, Portugal,
b Gynecology and Obstetrics Department, Centro Hospitalar do Alto Ave, Guimarães, Portugal,
c Department of Nephrology and Renal Transplantation, Centro Hospitalar do Porto (CHP-HSA),
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        "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Introducci&#243;n&#58; </span>La sexualidad&#44; el estatus psicosocial y la calidad de vida &#40;QoL&#41; son factores importantes&#44; a menudo infravalorados&#44; en los esquemas de di&#225;lisis&#46; <span class="elsevierStyleBold">Objetivos</span><span class="elsevierStyleBold">&#58;</span> Evaluar la prevalencia de disfunci&#243;n sexual y sus asociaciones en los pacientes en di&#225;lisis peritoneal &#40;DP&#41;&#46; <span class="elsevierStyleBold">M&#233;todos</span><span class="elsevierStyleBold">&#58;</span> Se utilizaron el &#205;ndice de Funci&#243;n Sexual Femenina &#40;IFSF&#41;&#44; el &#205;ndice Internacional de Funci&#243;n Er&#233;ctil &#40;IIFE&#41;&#44; la Escala de Ansiedad y Depresi&#243;n Hospitalaria &#40;HADS&#41; y los cuestionarios sobre calidad de vida EQ5D en la poblaci&#243;n prevalente en DP &#40;57 pacientes&#41;&#46; Se realizaron an&#225;lisis multivariantes para investigar los factores cl&#237;nicos independientes para disfunci&#243;n sexual&#46; <span class="elsevierStyleBold">Resultados</span><span class="elsevierStyleBold">&#58;</span> Se diagnostic&#243; disfunci&#243;n sexual en el 67&#44;9&#160;&#37; de las mujeres y en el 44&#44;8&#160;&#37; de los varones&#46; En las mujeres la alb&#250;mina s&#233;rica&#44; la creatinina&#44; los niveles de f&#243;sforo y EQ5D se relacionaran positivamente con IFSF&#46; En los varones exist&#237;a una correlaci&#243;n negativa entre el calcio s&#233;rico y el <span class="elsevierStyleItalic">score</span> IIEF&#46; En el an&#225;lisis multivariante los par&#225;metros nutricionales permanecieron asociados de manera independiente con la disfunci&#243;n sexual en mujeres&#59; en los varones los principales determinantes fueron el aumento de la concentraci&#243;n de calcio y la disminuci&#243;n de la testosterona&#46; En los an&#225;lisis de regresi&#243;n log&#237;stica el riesgo de disfunci&#243;n sexual en la poblaci&#243;n global est&#225; asociado a niveles menores de alb&#250;mina &#40;OR&#160;&#61;&#160;6&#44;94&#41; y a un <span class="elsevierStyleItalic">score</span> inferior de EQ5D &#40;OR&#160;&#61;&#160;6&#44;93&#41;&#46; <span class="elsevierStyleBold">Conclusiones&#58;</span> La disfunci&#243;n sexual tiene una alta prevalencia y una fuerte asociaci&#243;n con la percepci&#243;n de la calidad de vida de los pacientes en DP&#46; Se han encontrado diferentes variables cl&#237;nicas relacionadas con la disfunci&#243;n sexual en cada sexo que justifican actitudes preventivas y terap&#233;uticas individualizadas&#46;</p>"
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        "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Background&#58;</span> Sexual function&#44; psychosocial status and quality of life &#40;QoL&#41; are important dimensions&#44; often underestimated&#44; in dialysis treatment schedules&#46; <span class="elsevierStyleBold">Objectives&#58;</span> The aim of this study was to evaluate the prevalence of sexual dysfunction and its associations&#44; among peritoneal dialysis &#40;PD&#41; patients&#46; <span class="elsevierStyleBold">Methods&#58;</span> The Index of Female Sexual Function &#40;IFSF&#41;&#44; the International Index of Erectile Function &#40;IIEF&#41;&#44; the Hospital Anxiety and Depression Scale &#40;HADS&#41; and the Quality of Life EQ5D questionnaires were applied to a prevalent PD population of 57 enrolled patients&#46; Multivariate analysis was conducted to investigate clinical independent risk factors for sexual dysfunction&#46; <span class="elsevierStyleBold">Results&#58;</span> Sexual dysfunction was diagnosed in 67&#46;9&#37; of women and 44&#46;8&#37; of men&#46; In females&#44; serum albumin&#44; creatinine and phosphorus levels and EQ5D positively correlated with IFSF score&#46; For males&#44; there was a significant negative correlation between serum calcium levels and the IIEF score&#46; On multivariate analysis&#44; nutritional parameters remained independently associated with sexual dysfunction in women&#59; in males&#44; increase in calcium concentration and decrease of testosterone were main determinants&#46; On logistic regression analysis&#44; the risk of sexual dysfunction in global population was associated with lower values of albumin &#40;OR&#61;6&#46;94&#41; and with a lower QoL score EQ5D &#40;OR&#61;6&#46;93&#41;&#46; <span class="elsevierStyleBold">Conclusions&#58;</span> Sexual dysfunction is highly prevalent and strongly associated with impaired QoL of PD patients&#46; Different clinical variables were related to sexual dysfunction in each gender&#44; justifying an individualized preventive and therapeutic approaches&#46;</p>"
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ISSN: 02116995
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Idiomas
Nefrología
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¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?