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        "resumen" => "<p class="elsevierStylePara">La hipertensi&#243;n es uno de los principales problemas de salud p&#250;blica&#44; que afecta a muchas personas en todo el mundo&#46; Se sabe que es un importante factor de riesgo para el desarrollo de enfermedades cerebrovasculares y cardiovasculares&#46; Su clasificaci&#243;n como &#8220;primaria&#8221; o &#8220;secundaria&#8221; depende del proceso subyacente&#46; En el 5-10&#37; de los pacientes hipertensos&#44; se trata de un problema &#8220;secundario&#8221; a otro proceso de creciente frecuencia en los centros de atenci&#243;n terciaria&#46; Las causas m&#225;s frecuentes de la hipertensi&#243;n secundaria son&#58; enfermedades del par&#233;nquima renal&#44; estenosis de la arteria renal&#44; hiperaldosteronismo primario&#44; feocromocitoma y el s&#237;ndrome de Cushing&#46; La poliarteritis nodosa puede afectar a cualquier &#243;rgano y en diferentes grados&#46; A continuaci&#243;n presentamos a un paciente joven hipertenso al que se le ha diagnosticado poliarteritis nodosa&#44; cuya angiograf&#237;a muestra m&#250;ltiples microaneurismas que afectan al tronco cel&#237;aco&#44; a la arteria renal y a la arteria mesent&#233;rica superior&#44; asociada a un s&#237;ndrome de encefalopat&#237;a posterior reversible de entidad neurol&#243;gica poco visto&#46;</p>"
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        "resumen" => "<p class="elsevierStylePara">Hypertension &#40;HT&#41; represents a major public health problem affecting many individuals worldwide&#46; It is well known to be an important risk factor for the development of cerebrovascular and cardiovascular diseases&#46; Classifying hypertension as &#8216;primary&#8217; or &#8216;secondary&#8217; depends on the underlying mechanism&#46; In 5 to 10&#37; of hypertensive patients&#44; HT develops &#8216;secondary&#8217; to a separate mechanism that has been encountered with increasing frequency in the tertiary refferral centers&#46; The frequent causes of secondary hypertension include renal parenchymal disease&#44; renal artery stenosis&#44; primary hyperaldosteronism&#44; phaeochromocytoma and Cushing&#39;s syndrome&#46; Polyarteritis nodosa &#40;PAN&#41; can involve any organ and in varying degrees&#46; Here we present a young hypertensive patient diagnosed as PAN with the angiographic findings of multiple microaneurysms involving celiac&#44; renal and superior mesenteric arteries and associated with a rarely seen neurological entity-PRES syndrome&#46;</p>"
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                  "referenciaCompleta" => "Ebert EC, Hagspiel KD, Nagar M, Schlesinger N. Gastrointestinal involvement in polyarteritis nodosa. Clin Gastroenterol Hepatol 2008;6:960-6. <a href="http://www.ncbi.nlm.nih.gov/pubmed/18585977" target="_blank">[Pubmed]</a>"
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                  "referenciaCompleta" => "Martine G, Loïc G, Philippe LT, Pascal C, François L, Philippe C, et al. Long-term follow up of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: Analysis of four prospective trials including 278 patients. Arthritis Rheum 2001;44(3):666-75. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11263782" target="_blank">[Pubmed]</a>"
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                  "referenciaCompleta" => "Lightfoot RW Jr, Michel BA, Bloch DA, Hunder GG, Zvaifler NC, McShane DJ, et al. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 1990;33:1088-93. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1975174" target="_blank">[Pubmed]</a>"
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                  "referenciaCompleta" => "Pagnoux C, Seror R, Henegar C, Mahr A, Cohen P, Le Guern V, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French vasculitis study group database. Arthritis Rheum 2010;62:616-26. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20112401" target="_blank">[Pubmed]</a>"
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Complicación de la poliarteritis nodosa por síndrome de encefalopatía posterior reversible. Caso clínico
Polyarteritis nodosa complicated by posterior reversible encephalopathy syndrome: a case report
Alper Alpa, Hakan Akdama, Harun Akara, Kutsi Koseoglub, Ayca Ozkulc, Ibrahim Meteoglud, Yavuz Yenicerioglua
a Department of Nephrology, Adnan Menderes University. School of Medicine, Aydin, Turkey,
b Department of Radiology, Adnan Menderes University. School of Medicine, Aydin, Turkey,
c Department of Neurology, Adnan Menderes University. School of Medicine, Aydin, Turkey,
d Department of Pathology, Adnan Menderes University. School of Medicine, Aydin, Turkey,
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        "resumen" => "<p class="elsevierStylePara">La hipertensi&#243;n es uno de los principales problemas de salud p&#250;blica&#44; que afecta a muchas personas en todo el mundo&#46; Se sabe que es un importante factor de riesgo para el desarrollo de enfermedades cerebrovasculares y cardiovasculares&#46; Su clasificaci&#243;n como &#8220;primaria&#8221; o &#8220;secundaria&#8221; depende del proceso subyacente&#46; En el 5-10&#37; de los pacientes hipertensos&#44; se trata de un problema &#8220;secundario&#8221; a otro proceso de creciente frecuencia en los centros de atenci&#243;n terciaria&#46; Las causas m&#225;s frecuentes de la hipertensi&#243;n secundaria son&#58; enfermedades del par&#233;nquima renal&#44; estenosis de la arteria renal&#44; hiperaldosteronismo primario&#44; feocromocitoma y el s&#237;ndrome de Cushing&#46; La poliarteritis nodosa puede afectar a cualquier &#243;rgano y en diferentes grados&#46; A continuaci&#243;n presentamos a un paciente joven hipertenso al que se le ha diagnosticado poliarteritis nodosa&#44; cuya angiograf&#237;a muestra m&#250;ltiples microaneurismas que afectan al tronco cel&#237;aco&#44; a la arteria renal y a la arteria mesent&#233;rica superior&#44; asociada a un s&#237;ndrome de encefalopat&#237;a posterior reversible de entidad neurol&#243;gica poco visto&#46;</p>"
      ]
      "en" => array:1 [
        "resumen" => "<p class="elsevierStylePara">Hypertension &#40;HT&#41; represents a major public health problem affecting many individuals worldwide&#46; It is well known to be an important risk factor for the development of cerebrovascular and cardiovascular diseases&#46; Classifying hypertension as &#8216;primary&#8217; or &#8216;secondary&#8217; depends on the underlying mechanism&#46; In 5 to 10&#37; of hypertensive patients&#44; HT develops &#8216;secondary&#8217; to a separate mechanism that has been encountered with increasing frequency in the tertiary refferral centers&#46; The frequent causes of secondary hypertension include renal parenchymal disease&#44; renal artery stenosis&#44; primary hyperaldosteronism&#44; phaeochromocytoma and Cushing&#39;s syndrome&#46; Polyarteritis nodosa &#40;PAN&#41; can involve any organ and in varying degrees&#46; Here we present a young hypertensive patient diagnosed as PAN with the angiographic findings of multiple microaneurysms involving celiac&#44; renal and superior mesenteric arteries and associated with a rarely seen neurological entity-PRES syndrome&#46;</p>"
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    "bibliografia" => array:2 [
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                0 => array:3 [
                  "referenciaCompleta" => "Ebert EC, Hagspiel KD, Nagar M, Schlesinger N. Gastrointestinal involvement in polyarteritis nodosa. Clin Gastroenterol Hepatol 2008;6:960-6. <a href="http://www.ncbi.nlm.nih.gov/pubmed/18585977" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
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                0 => array:3 [
                  "referenciaCompleta" => "Martine G, Loïc G, Philippe LT, Pascal C, François L, Philippe C, et al. Long-term follow up of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: Analysis of four prospective trials including 278 patients. Arthritis Rheum 2001;44(3):666-75. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11263782" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Lie JT. Systemic, pulmonary and cerebral vasculitis. In: Stehbens WE, Lie JT, eds. Vascular pathology. London: Chapman & Hall; 1995. pp. 623-56."
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                  ]
                  "host" => array:1 [
                    0 => null
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              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Zeek PM. Periarteritis nodosa and other forms of necrotizing angiitis. N Engl J Med 1953;278:764-22."
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            ]
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              "referencia" => array:1 [
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                  "referenciaCompleta" => "Watts RA, Lane SE, Bentham G, Scott DG. Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. Arthritis Rheum 2000;43:414-9. <a href="http://www.ncbi.nlm.nih.gov/pubmed/10693883" target="_blank">[Pubmed]</a>"
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                  ]
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              "identificador" => "bib6"
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              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Lightfoot RW Jr, Michel BA, Bloch DA, Hunder GG, Zvaifler NC, McShane DJ, et al. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 1990;33:1088-93. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1975174" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
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                    0 => null
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              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Stone JH. Polyarteritis nodosa. JAMA 2002;288:1632-9. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12350194" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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                    0 => null
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              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Pagnoux C, Seror R, Henegar C, Mahr A, Cohen P, Le Guern V, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French vasculitis study group database. Arthritis Rheum 2010;62:616-26. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20112401" target="_blank">[Pubmed]</a>"
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                    0 => null
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              "identificador" => "bib9"
              "etiqueta" => "9"
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                0 => array:3 [
                  "referenciaCompleta" => "JCS Joint Working Group. Guideline for management of vasculitis syndrome (JCS 2008). Japanese Circulation Society. Circ J 2011;75:474-503."
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                    0 => null
                  ]
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                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Yang HC, Lee S, Kim W, Park SK, Han YM, Kang KP. Spontaneous perirenal hematoma due to multiple renal artery aneurysms in a patient with presumed polyarteritis nodosa. Vasc Med 2012;17:427-8. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22836225" target="_blank">[Pubmed]</a>"
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                    0 => null
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            11 => array:3 [
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              "identificador" => "bib13"
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              "identificador" => "bib14"
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            14 => array:3 [
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            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
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              "identificador" => "bib18"
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                  "contribucion" => array:1 [
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            25 => array:3 [
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                0 => array:3 [
                  "referenciaCompleta" => "Pontes TC, Rufino GP, Gurgel MG, Medeiros AC, Freire EA. Fibromuscular dysplasia: a differential diagnosis of vasculitis. Rev Bras Reumatol 2012;52:70-4. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22286647" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Yoon SD, Cho BM, Oh SM, Park SH, Jang IB, Lee JY. Clinical and radiological spectrum of posterior reversible encephalopathy syndrome. J Cerebrovasc Endovasc Neurosurg 2013;15:206-13. <a href="http://www.ncbi.nlm.nih.gov/pubmed/24167801" target="_blank">[Pubmed]</a>"
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