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        "resumen" => "<p class="elsevierStylePara">El fosfato no goza de buena reputaci&#243;n entre los nefr&#243;logos&#46; Se asocia con la calcificaci&#243;n vascular y con una gran mortalidad cuando sus niveles en sangre son elevados&#46; Provoca da&#241;os en las c&#233;lulas endoteliales vasculares y transformaci&#243;n osteobl&#225;stica en las c&#233;lulas de los m&#250;sculos lisos vasculares en cultivos&#46; Aunque muchos de los resultados adversos en los pacientes con enfermedad renal cr&#243;nica &#40;ERC&#41; se atribuyen al fosfato&#44; se desconoce el mecanismo molecular preciso que hay detr&#225;s de los problemas que causa&#46; Este d&#233;ficit de conocimiento ha limitado las opciones terap&#233;uticas a la restricci&#243;n del fosfato en la dieta&#44; a captores del fosfato y a la eliminaci&#243;n forzada del fosfato a trav&#233;s de di&#225;lisis&#46; El objetivo de esta revisi&#243;n es llamar la atenci&#243;n de los nefr&#243;logos sobre un metabolito del fosfato denominado part&#237;culas de calciprote&#237;nas &#40;PCP&#41;&#46; Se est&#225; discutiendo la posibilidad de las PCP como pat&#243;geno y nuevo objetivo terap&#233;utico de la ERC&#46;</p>"
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Partículas de calciproteínas (PCP): ¿verdaderas culpables de los problemas causados por el fósforo?
Calciprotein particle (CPP): a true culprit of phosphorus woes?
Makoto Kuro-oa
a Center for Molecular Medicine. Jichi Medial University, Shimotsuke, Tochigi (Japan), Department of Pathology, Center for Mineral Metabolism, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.,
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