Primer Informe del Comité de Anemia en Pacientes en Hemodiálisis Crónica de la Sociedad Latinoamericana de Nefrología e Hipertensión (SLANH)
The First Report of The Latin American Society of Nephrology and Hypertension (SLANH) Anemia Committee in Chronic Hemodialysis Patients
Raúl Carlinia, Raul Carlinia, Gregorio Obradorb, Nieves Campistrúsc, Liliana Andraded, Liliana Chifflete, Rachel Bregmanf, Alberto Locatellig, Ricardo Correa-Rotterh, Hugo Pobletei
a Division of Nephrology, University Hospital of Caracas, Caracas, Venezuela,
b School of Medicine, Panamerican University, Ciudad City, México,
c Dialysis Center Uruguayana, Montevideo, Uruguay,
d Hospital Policial Medical Complex Churruca-Visca, Buenos Aires, Argentina,
e Division of Dialysis, San José Medical Association, San José de Mayo, Uruguay,
f Rio de Janeiro State University, Rio de Janeiro, Brazil,
g Nefronosa Service SA, Buenos Aires,
h Department of Nephrology and Mineral Metabolism, Institute of Nutrition, Salvador Zubirán, Mexico City, Mexico,
i Dialysis Center Sermedial, Valparaíso, Chile,
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"entidad" => "Division of Dialysis, San José Medical Association, San José de Mayo, Uruguay, " "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "affe" ] 5 => array:3 [ "entidad" => " Rio de Janeiro State University, Rio de Janeiro, Brazil, " "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "afff" ] 6 => array:3 [ "entidad" => " Nefronosa Service SA, Buenos Aires, " "etiqueta" => "<span class="elsevierStyleSup">g</span>" "identificador" => "affg" ] 7 => array:3 [ "entidad" => "Department of Nephrology and Mineral Metabolism, Institute of Nutrition, Salvador Zubirán, Mexico City, Mexico, " "etiqueta" => "<span class="elsevierStyleSup">h</span>" "identificador" => "affh" ] 8 => array:3 [ "entidad" => " Dialysis Center Sermedial, Valparaíso, Chile, " "etiqueta" => "<span class="elsevierStyleSup">i</span>" "identificador" => "affi" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The First Report of The Latin American Society of Nephrology and Hypertension (SLANH) Anemia Committee in Chronic Hemodialysis Patients" ] ] "pdfFichero" => "P1-E565-S4483-A12234.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:4 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec433267" "palabras" => array:1 [ 0 => "Encuesta" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec433269" "palabras" => array:1 [ 0 => "Hemodiálisis" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec433271" "palabras" => array:1 [ 0 => "Latinoamérica" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec433273" "palabras" => array:1 [ 0 => "Anemia" ] ] ] "en" => array:4 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec433268" "palabras" => array:1 [ 0 => "Survey" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec433270" "palabras" => array:1 [ 0 => "Hemodialysis" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec433272" "palabras" => array:1 [ 0 => "Latin America" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec433274" "palabras" => array:1 [ 0 => "Anemia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Antecedentes: </span>La anemia representa una complicación frecuente en pacientes con enfermedad renal crónica. En Latinoamérica (LA) la prevalencia y características de la anemia en pacientes en hemodiálisis (HD) no ha sido bien estudiada. <span class="elsevierStyleBold">Objetivo: </span>Evaluar los resultados del primer registro de anemia del Comité de Anemia de la Sociedad Latinoamericana de Nefrología e Hipertensión. <span class="elsevierStyleBold">Métodos: </span>Esta es una encuesta multinacional, voluntaria, que recolectó datos sobre el tratamiento de la anemia en pacientes en HD de unidades independientes en LA entre septiembre de 2009 y marzo de 2010. Para el análisis estadístico se utilizaron los siguientes métodos: t-test, ANOVA, chi<span class="elsevierStyleSup">2</span> y el análisis de regresión logística multivariante. <span class="elsevierStyleBold">Resultados:</span> La encuesta fue respondida por 134 unidades de HD de 16 países, recibiéndose datos de 9025 pacientes. Las medias ± desviación estándar de Hb, ferritina y del índice de saturación de transferrina (IST) fueron respectivamente: 10,5 ± 1,8 g/dl, 570 ± 539 µg/l y 29,8 % ± 15. Se administró agentes estimulantes de la eritropoyesis (AEE) al 84,3 % de los pacientes y hierro intravenoso (FeIV) al 68,3 %. Solamente el 32,7 % de los pacientes tuvieron una Hb blanco de 10,5-12,0 g/dl. En pacientes con Hb < 10,5 g/dl, el 85,2 % estaban recibiendo AEE y un 68 % FeIV. Las variables independientes asociadas con nivel Hb < 10,5 g/dl fueron: género femenino, IST < 25 % y edad < 50 años.  En la muestra de pacientes analizada, a pesar del amplio uso de los AEE y FeIV, casi la mitad de los pacientes no alcanzó la Hb blanco.</p>" ] "en" => array:1 [ "resumen" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">Background: </span>Anemia almost invariably occurs in patients with chronic kidney disease. Limited data are available regarding anemia management in Latin American (LA) hemodialysis (HD) patients. <span class="elsevierStyleBold">Objective</span>: To evaluate the results of the first anemia survey of the Anemia Committee of the SLANH. <span class="elsevierStyleBold">Methods:</span> This is a multinational, voluntary survey that collected anemia management data from adult HD patients from independent, non-chain owned HD units, between 09/2009 and 03/2010. T-test, ANOVA, chi-square test and multivariate logistic regression were used for statistical analysis. <span class="elsevierStyleBold">Results: </span>The survey received responses from 134 HD units of 16 countries providing data from 9,025 patients. Mean values of Hb, ferritin, and transferrin saturation (TSAT) were 10.5±1.8g/dL, 570±539µg/l, and 29.8±15%, respectively. Only 32.7% of patients were within the Hb target of 10.5-12.0g/dL (46.3% were below and 21.1% above). Erythropoietin-stimulating agents (ESAs) were administered to 84.3% patients and 68.3% received intravenous iron (IV). Iron deficiency (TSAT≤20%) was present in 27.5% patients and among those receiving erythropoietin, 47% did not achieve Hb target. The independent variables associated with the lowest Hb level (<10.5g/dL) were: female gender, TSAT¿25% and age<50 years. <span class="elsevierStyleBold">Conclusions: </span>According to these results, nearly half of LA chronic HD patients did not achieve the recommended Hb target despite wide use of ESAs and IV iron.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Singh AK, Szczech L, Tang KL, Barnhart H, Sapp S, Wolfson M, et al. for the CHOIR Investigators. Correction of Anemia with Epoetin Alfa in Chronic Kidney Disease. N Engl J Med 2006;355:2085-98. <a href="http://www.ncbi.nlm.nih.gov/pubmed/17108343" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:1 [ "itemHostRev" => array:3 [ "pii" => "S1472648309002806" "estado" => "S300" "issn" => "14726483" ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Drüeke TB, Locatelli F, Clyne N, Eckardt K-U, Macdougall IC, Tsakiris D, et al. for the CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 10 | 9 | 19 |
| 2024 Octubre | 57 | 73 | 130 |
| 2024 Septiembre | 63 | 54 | 117 |
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| 2023 Septiembre | 53 | 38 | 91 |
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| 2023 Julio | 44 | 37 | 81 |
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| 2023 Enero | 43 | 265 | 308 |
| 2022 Diciembre | 78 | 99 | 177 |
| 2022 Noviembre | 73 | 47 | 120 |
| 2022 Octubre | 66 | 73 | 139 |
| 2022 Septiembre | 46 | 53 | 99 |
| 2022 Agosto | 56 | 64 | 120 |
| 2022 Julio | 52 | 80 | 132 |
| 2022 Junio | 37 | 63 | 100 |
| 2022 Mayo | 42 | 52 | 94 |
| 2022 Abril | 61 | 61 | 122 |
| 2022 Marzo | 44 | 48 | 92 |
| 2022 Febrero | 42 | 58 | 100 |
| 2022 Enero | 38 | 49 | 87 |
| 2021 Diciembre | 46 | 57 | 103 |
| 2021 Noviembre | 45 | 58 | 103 |
| 2021 Octubre | 45 | 60 | 105 |
| 2021 Septiembre | 48 | 60 | 108 |
| 2021 Agosto | 30 | 38 | 68 |
| 2021 Julio | 30 | 40 | 70 |
| 2021 Junio | 53 | 35 | 88 |
| 2021 Mayo | 46 | 44 | 90 |
| 2021 Abril | 134 | 101 | 235 |
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| 2021 Enero | 55 | 30 | 85 |
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| 2020 Octubre | 42 | 23 | 65 |
| 2020 Septiembre | 32 | 16 | 48 |
| 2020 Agosto | 47 | 32 | 79 |
| 2020 Julio | 30 | 22 | 52 |
| 2020 Junio | 25 | 24 | 49 |
| 2020 Mayo | 47 | 31 | 78 |
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| 2020 Febrero | 43 | 47 | 90 |
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| 2019 Octubre | 32 | 21 | 53 |
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| 2017 Octubre | 41 | 17 | 58 |
| 2017 Septiembre | 38 | 27 | 65 |
| 2017 Agosto | 47 | 23 | 70 |
| 2017 Julio | 55 | 28 | 83 |
| 2017 Junio | 60 | 42 | 102 |
| 2017 Mayo | 72 | 32 | 104 |
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| 2017 Marzo | 63 | 26 | 89 |
| 2017 Febrero | 47 | 16 | 63 |
| 2017 Enero | 35 | 10 | 45 |
| 2016 Diciembre | 123 | 14 | 137 |
| 2016 Noviembre | 128 | 18 | 146 |
| 2016 Octubre | 171 | 10 | 181 |
| 2016 Septiembre | 224 | 9 | 233 |
| 2016 Agosto | 312 | 7 | 319 |
| 2016 Julio | 300 | 11 | 311 |
| 2016 Junio | 165 | 0 | 165 |
| 2016 Mayo | 171 | 0 | 171 |
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| 2016 Marzo | 132 | 0 | 132 |
| 2016 Febrero | 162 | 0 | 162 |
| 2016 Enero | 166 | 0 | 166 |
| 2015 Diciembre | 157 | 0 | 157 |
| 2015 Noviembre | 174 | 0 | 174 |
| 2015 Octubre | 187 | 0 | 187 |
| 2015 Septiembre | 141 | 0 | 141 |
| 2015 Agosto | 157 | 0 | 157 |
| 2015 Julio | 197 | 0 | 197 |
| 2015 Junio | 133 | 0 | 133 |
| 2015 Mayo | 180 | 0 | 180 |
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| 2015 Febrero | 1849 | 0 | 1849 |
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