array:24 [
  "pii" => "S0211699515001393"
  "issn" => "02116995"
  "doi" => "10.1016/j.nefro.2015.09.001"
  "estado" => "S300"
  "fechaPublicacion" => "2016-03-01"
  "aid" => "87"
  "copyright" => "Sociedad Española de Nefrología"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Nefrologia. 2016;36:182-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 6548
    "formatos" => array:3 [
      "EPUB" => 375
      "HTML" => 5271
      "PDF" => 902
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0211699515000880"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2015.05.028"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "71"
    "copyright" => "Sociedad Española de Nefrología"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Nefrologia. 2016;36:184-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 7098
      "formatos" => array:3 [
        "EPUB" => 300
        "HTML" => 5913
        "PDF" => 885
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director&#58; Comentarios breves sobre casos cl&#237;nicos</span>"
      "titulo" => "Pielonefritis enfisematosa en trasplantado renal&#46; Reporte de un caso"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "184"
          "paginaFinal" => "186"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Emphysematous pyelonephritis in a renal transplant recipient&#46; A case report"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 544
              "Ancho" => 1459
              "Tamanyo" => 95399
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">TAC abdominal&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Hermann Hern&#225;ndez-Vargas, Milagros Sierra-Carpio, Fernando Gil-Catalinas, Altagracia Bello-Ovalle, In&#233;s Beired-Val, Gabriela In&#233;s Pimentel-Guzm&#225;n, Antonio Gil-Para&#237;so, Marta Artamendi-Larra&#241;aga, Cecilia Dall-Anesse, Emma Huarte-Loza"
          "autores" => array:10 [
            0 => array:2 [
              "nombre" => "Hermann"
              "apellidos" => "Hern&#225;ndez-Vargas"
            ]
            1 => array:2 [
              "nombre" => "Milagros"
              "apellidos" => "Sierra-Carpio"
            ]
            2 => array:2 [
              "nombre" => "Fernando"
              "apellidos" => "Gil-Catalinas"
            ]
            3 => array:2 [
              "nombre" => "Altagracia"
              "apellidos" => "Bello-Ovalle"
            ]
            4 => array:2 [
              "nombre" => "In&#233;s"
              "apellidos" => "Beired-Val"
            ]
            5 => array:2 [
              "nombre" => "Gabriela In&#233;s"
              "apellidos" => "Pimentel-Guzm&#225;n"
            ]
            6 => array:2 [
              "nombre" => "Antonio"
              "apellidos" => "Gil-Para&#237;so"
            ]
            7 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Artamendi-Larra&#241;aga"
            ]
            8 => array:2 [
              "nombre" => "Cecilia"
              "apellidos" => "Dall-Anesse"
            ]
            9 => array:2 [
              "nombre" => "Emma"
              "apellidos" => "Huarte-Loza"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2013251415001029"
        "doi" => "10.1016/j.nefroe.2015.11.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251415001029?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515000880?idApp=UINPBA000064"
    "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515000880/v3_201704120115/es/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0211699515001654"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2015.08.009"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "113"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia. 2016;36:181-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6166
      "formatos" => array:3 [
        "EPUB" => 323
        "HTML" => 5043
        "PDF" => 800
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cartas al Director&#58; Comentarios breves sobre casos cl&#237;nicos</span>"
      "titulo" => "Fracaso renal agudo secundario a rabdomi&#243;lisis por estatinas en una paciente nonagenaria&#46; Lecciones a tener en cuenta"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "181"
          "paginaFinal" => "182"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Acute kidney injury secondary to rhabdomyolysis in a nonagenarian patient taking statins&#46; Lessons to be considered"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jose Maria Pe&#241;a-Porta, Alba Martinez-Burillo, Oscar Urbano-Gonzalo, Rafael Alvarez-Lipe"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Jose Maria"
              "apellidos" => "Pe&#241;a-Porta"
            ]
            1 => array:2 [
              "nombre" => "Alba"
              "apellidos" => "Martinez-Burillo"
            ]
            2 => array:2 [
              "nombre" => "Oscar"
              "apellidos" => "Urbano-Gonzalo"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Alvarez-Lipe"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2013251416000213"
        "doi" => "10.1016/j.nefroe.2015.08.006"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000213?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001654?idApp=UINPBA000064"
    "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515001654/v3_201704120115/es/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Acute renal colic&#58; Beyond kidney stones"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "182"
        "paginaFinal" => "184"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Sandra Silva, Martinho Almeida, Lurdes Rodrigues, Maximino Costa"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Sandra"
            "apellidos" => "Silva"
            "email" => array:1 [
              0 => "oliveirasilva&#46;sandra&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Martinho"
            "apellidos" => "Almeida"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Lurdes"
            "apellidos" => "Rodrigues"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Maximino"
            "apellidos" => "Costa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Unidade de Nefrologia&#44; Departamento de Medicina&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Unidade de Hematologia&#44; Departamento de Medicina&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servi&#231;o de Urologia&#44; Departamento de Cirurgia&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "C&#243;lico renal agudo&#58; m&#225;s all&#225; de los c&#225;lculos renales"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 3651
            "Ancho" => 1667
            "Tamanyo" => 499274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; B&#44; C&#58; Sagital&#44; coronal and axial sections of abdominal computed tomography revealing structural heterogeneity of the left renal parenquima with diminished enhancement at the tip of the medullary pyramid and the presence of small cavities filled by contrast on the borders of the small calices &#8211; aspects highly suggestive of papillary necrosis ischemia&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 59-year-old woman without relevant past medical history presented with hematuria and renal colic&#46; After a negative diagnostic work-up&#44; sickling vaso-occlusive crisis in the setting of sickle cell trait &#40;SCT&#41; was diagnosed&#46; This report aims to raise awareness that SCT should be included in the differential diagnosis of unexplained hematuria and&#47;or renal colic&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Renal abnormalities are frequently described in patients with sickle hemoglobinopathies&#44; but SCT patients &#40;heterozygous carriers&#44; with one sickle cell gene and one normal gene&#41; are mostly asymptomatic&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> However sickle cell crisis can occur if the patient is exposed to hypoxic conditions&#44; high altitude and intense physical exercise&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Acute events include vaso-occlusive crises such as papillary necrosis of the kidney&#44; ischemic stroke and infections&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">A 59-year-old Caucasian woman presented with dark-red urine and colicky pain in the left flank&#46; She had no fever&#44; dysuria&#44; urinary urgency and no history of trauma&#44; nephrolithiasis or additional episodes of hematuria&#46; She was of Asian ascendancy and had non-consanguineous parents&#46; Her medical history was unremarkable&#44; except for hypertension&#46; Her chronic medication consisted of candesartan&#47;hydrochlorothiazide and she denied non-steroidal anti-inflammatory drugs use&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Physical examination revealed modest overweight&#44; blood pressure of 110&#47;60<span class="elsevierStyleHsp" style=""></span>mmHg&#44; no evidence of hepatosplenomegaly&#44; although left costovertebral tenderness was noted&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Laboratory tests showed normal blood cell counts&#44; coagulation parameters&#44; electrolytes&#44; and renal and hepatic tests&#46; No rhabdomyolysis nor hemolysis were present&#46; Urine dipstick revealed a specific gravity of 1&#46;010&#44; 3&#43; hemoglobin and no protein&#59; the microscopic exam showed 168 red blood cells per high power field&#44; but no casts or white blood cells&#46; Urine cultures&#44; including for mycobacteria&#44; were negative&#46; She had no anomalous cells in cytology and a normal cystoscopy&#46; A computed tomography scan &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#8211;C&#41; suggested renal papillary necrosis and excluded other abnormalities&#46; There were no criteria for diabetes mellitus&#46; Hemoglobin&#39;s electrophoresis showed the presence of an abnormal hemoglobin &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; which was subsequently documented to be HbS&#46; A molecular study revealed an heterozygosity for the hemoglobin sickle mutation of the &#946;-globin gene &#40;HBB&#58;c&#46;20A&#62;T&#41; establishing a diagnosis of SCT&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">Clinical findings resolved after conservative therapy with rest&#44; hydration and analgesia&#46; The patient was recommended to avoid circumstances that may precipitate vaso-occlusive crises&#46; Her daughter was referred for genetic testing&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">SCT is generally asymptomatic&#44; although occasionally associated with significant morbidity&#44; including papillary necrosis&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> It is a highly prevalent recessive illness&#44; mainly found in African but also in Asian populations&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> In SCT patients&#44; HbS is abnormally found with plasma concentrations typically between 35&#37; and 45&#37; of total hemoglobin&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Hematuria is the most common complication<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> of SCT&#44; but the usual etiologies&#44; such as stones&#44; urinary tract infections or neoplasms should be considered first&#46; Hence&#44; initial testing must include urine analysis&#44; culture&#44; cytology and imaging studies&#46; In SCT patients&#44; occlusion of small vessels by sickled blood cells&#44; causes microthrombi and ischaemia&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> In the kidneys&#44; this obstruction is predominantly apparent in the renal papilla due to their marginal blood supply&#46; Papillary necrosis can be difficult to diagnose&#46; The presence of sloughed papillae in the urine examination is diagnostic&#44; but has low sensitivity&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> In our patient an ultrasound and a tomography scan allowed the diagnosis&#46; Treatment is usually conservative&#44; but adjuvant therapies &#40;desmopressin or epsilon-amino caproic acid&#41; can be of benefit&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Most severe cases may require arterial embolization or surgical exploration&#46; The outcome is generally good but the patient must be informed about avoidable precipitating conditions and genetic counseling&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Hemoglobin&#39;s electrophoresis should be part of the diagnostic work-up of renal colic and&#47;or hematuria&#44; namely in patients whose etiology has never been established&#46;</p><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest related to the contents of this article&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflict of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 3651
            "Ancho" => 1667
            "Tamanyo" => 499274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; B&#44; C&#58; Sagital&#44; coronal and axial sections of abdominal computed tomography revealing structural heterogeneity of the left renal parenquima with diminished enhancement at the tip of the medullary pyramid and the presence of small cavities filled by contrast on the borders of the small calices &#8211; aspects highly suggestive of papillary necrosis ischemia&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1417
            "Ancho" => 1667
            "Tamanyo" => 69796
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hemoglobin electrophoresis &#40;cellulose acetate&#41;&#58; amino acids substitution in hemoglobin variants alter charge and subsequently hemoglobin&#39;s mobility pattern&#46; Presence of an abnormal hemoglobin variant in Z5 region&#44; compatible with HbS &#40;<span class="elsevierStyleBold">&#42;</span>&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle cell trait and gross hematuria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46; Kiryluk"
                            1 => "A&#46; Jadoon"
                            2 => "M&#46; Gupta"
                            3 => "J&#46; Radhakrishnan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.ki.5002060"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2007"
                        "volumen" => "71"
                        "paginaInicial" => "706"
                        "paginaFinal" => "710"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17191080"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal abnormalities in sickle cell disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46;P&#46; Phuong-Thu"
                            1 => "T&#46;P&#46; Phuong-Chi"
                            2 => "H&#46;W&#46; Alan"
                            3 => "Q&#46;L&#46; Susie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1755.2000.07501.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2000"
                        "volumen" => "57"
                        "paginaInicial" => "1"
                        "paginaFinal" => "8"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10828753"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle cell anaemia&#46; Agenda item 11&#46;4&#44; in 59th World Health Assembly&#44; 27 May 2006"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "World Health Organisation"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2006"
                        "editorial" => "World Health Organisation"
                        "editorialLocalizacion" => "Geneva&#44; Switzerland"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle-cell anemia&#58; a look at global haplotype distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Gabriel"
                            1 => "J&#46; Przybylski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nat Educ"
                        "fecha" => "2010"
                        "volumen" => "3"
                        "numero" => "3"
                        "paginaInicial" => "2"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal papillary necrosis&#58; review and comparison of findings at multi-detector row CT and intravenous urography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Dae Chul Jung"
                            1 => "Seung Hyup Kim"
                            2 => "Jung Sung II"
                            3 => "Hwang Sung II"
                            4 => "Sun Ho Kim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/rg.266065039"
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiographics"
                        "fecha" => "2006"
                        "volumen" => "26"
                        "paginaInicial" => "1827"
                        "paginaFinal" => "1836"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17102053"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515001393/v3_201704120115/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "43981"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Cartas al Director&#58; Comentarios breves sobre casos cl&#237;nicos"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/02116995/0000003600000002/v3_201704120115/S0211699515001393/v3_201704120115/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001393?idApp=UINPBA000064"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Letter to the Editor
Acute renal colic: Beyond kidney stones
Cólico renal agudo: más allá de los cálculos renales
Sandra Silvaa,
Autor para correspondencia
oliveirasilva.sandra@gmail.com

Corresponding author.
, Martinho Almeidab, Lurdes Rodriguesc, Maximino Costaa
a Unidade de Nefrologia, Departamento de Medicina, Hospital Pedro Hispano, Matosinhos, Portugal
b Unidade de Hematologia, Departamento de Medicina, Hospital Pedro Hispano, Matosinhos, Portugal
c Serviço de Urologia, Departamento de Cirurgia, Hospital Pedro Hispano, Matosinhos, Portugal
Leído
11585
Veces
se ha leído el artículo
3125
Total PDF
8460
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S0211699515001393"
  "issn" => "02116995"
  "doi" => "10.1016/j.nefro.2015.09.001"
  "estado" => "S300"
  "fechaPublicacion" => "2016-03-01"
  "aid" => "87"
  "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 0
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Nefrologia. 2016;36:182-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 6548
    "formatos" => array:3 [
      "EPUB" => 375
      "HTML" => 5271
      "PDF" => 902
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S0211699515000880"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2015.05.028"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "71"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Nefrologia. 2016;36:184-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 7098
      "formatos" => array:3 [
        "EPUB" => 300
        "HTML" => 5913
        "PDF" => 885
      ]
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director&#58; Comentarios breves sobre casos cl&#237;nicos</span>"
      "titulo" => "Pielonefritis enfisematosa en trasplantado renal&#46; Reporte de un caso"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "184"
          "paginaFinal" => "186"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Emphysematous pyelonephritis in a renal transplant recipient&#46; A case report"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 544
              "Ancho" => 1459
              "Tamanyo" => 95399
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">TAC abdominal&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Hermann Hern&#225;ndez-Vargas, Milagros Sierra-Carpio, Fernando Gil-Catalinas, Altagracia Bello-Ovalle, In&#233;s Beired-Val, Gabriela In&#233;s Pimentel-Guzm&#225;n, Antonio Gil-Para&#237;so, Marta Artamendi-Larra&#241;aga, Cecilia Dall-Anesse, Emma Huarte-Loza"
          "autores" => array:10 [
            0 => array:2 [
              "nombre" => "Hermann"
              "apellidos" => "Hern&#225;ndez-Vargas"
            ]
            1 => array:2 [
              "nombre" => "Milagros"
              "apellidos" => "Sierra-Carpio"
            ]
            2 => array:2 [
              "nombre" => "Fernando"
              "apellidos" => "Gil-Catalinas"
            ]
            3 => array:2 [
              "nombre" => "Altagracia"
              "apellidos" => "Bello-Ovalle"
            ]
            4 => array:2 [
              "nombre" => "In&#233;s"
              "apellidos" => "Beired-Val"
            ]
            5 => array:2 [
              "nombre" => "Gabriela In&#233;s"
              "apellidos" => "Pimentel-Guzm&#225;n"
            ]
            6 => array:2 [
              "nombre" => "Antonio"
              "apellidos" => "Gil-Para&#237;so"
            ]
            7 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Artamendi-Larra&#241;aga"
            ]
            8 => array:2 [
              "nombre" => "Cecilia"
              "apellidos" => "Dall-Anesse"
            ]
            9 => array:2 [
              "nombre" => "Emma"
              "apellidos" => "Huarte-Loza"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2013251415001029"
        "doi" => "10.1016/j.nefroe.2015.11.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251415001029?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515000880?idApp=UINPBA000064"
    "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515000880/v3_201704120115/es/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S0211699515001654"
    "issn" => "02116995"
    "doi" => "10.1016/j.nefro.2015.08.009"
    "estado" => "S300"
    "fechaPublicacion" => "2016-03-01"
    "aid" => "113"
    "copyright" => "Sociedad Espa&#241;ola de Nefrolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 0
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Nefrologia. 2016;36:181-2"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 6166
      "formatos" => array:3 [
        "EPUB" => 323
        "HTML" => 5043
        "PDF" => 800
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cartas al Director&#58; Comentarios breves sobre casos cl&#237;nicos</span>"
      "titulo" => "Fracaso renal agudo secundario a rabdomi&#243;lisis por estatinas en una paciente nonagenaria&#46; Lecciones a tener en cuenta"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "181"
          "paginaFinal" => "182"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Acute kidney injury secondary to rhabdomyolysis in a nonagenarian patient taking statins&#46; Lessons to be considered"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jose Maria Pe&#241;a-Porta, Alba Martinez-Burillo, Oscar Urbano-Gonzalo, Rafael Alvarez-Lipe"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Jose Maria"
              "apellidos" => "Pe&#241;a-Porta"
            ]
            1 => array:2 [
              "nombre" => "Alba"
              "apellidos" => "Martinez-Burillo"
            ]
            2 => array:2 [
              "nombre" => "Oscar"
              "apellidos" => "Urbano-Gonzalo"
            ]
            3 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Alvarez-Lipe"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2013251416000213"
        "doi" => "10.1016/j.nefroe.2015.08.006"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251416000213?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001654?idApp=UINPBA000064"
    "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515001654/v3_201704120115/es/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Acute renal colic&#58; Beyond kidney stones"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "182"
        "paginaFinal" => "184"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Sandra Silva, Martinho Almeida, Lurdes Rodrigues, Maximino Costa"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Sandra"
            "apellidos" => "Silva"
            "email" => array:1 [
              0 => "oliveirasilva&#46;sandra&#64;gmail&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Martinho"
            "apellidos" => "Almeida"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Lurdes"
            "apellidos" => "Rodrigues"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Maximino"
            "apellidos" => "Costa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Unidade de Nefrologia&#44; Departamento de Medicina&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Unidade de Hematologia&#44; Departamento de Medicina&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servi&#231;o de Urologia&#44; Departamento de Cirurgia&#44; Hospital Pedro Hispano&#44; Matosinhos&#44; Portugal"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "C&#243;lico renal agudo&#58; m&#225;s all&#225; de los c&#225;lculos renales"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 3651
            "Ancho" => 1667
            "Tamanyo" => 499274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; B&#44; C&#58; Sagital&#44; coronal and axial sections of abdominal computed tomography revealing structural heterogeneity of the left renal parenquima with diminished enhancement at the tip of the medullary pyramid and the presence of small cavities filled by contrast on the borders of the small calices &#8211; aspects highly suggestive of papillary necrosis ischemia&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 59-year-old woman without relevant past medical history presented with hematuria and renal colic&#46; After a negative diagnostic work-up&#44; sickling vaso-occlusive crisis in the setting of sickle cell trait &#40;SCT&#41; was diagnosed&#46; This report aims to raise awareness that SCT should be included in the differential diagnosis of unexplained hematuria and&#47;or renal colic&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Renal abnormalities are frequently described in patients with sickle hemoglobinopathies&#44; but SCT patients &#40;heterozygous carriers&#44; with one sickle cell gene and one normal gene&#41; are mostly asymptomatic&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> However sickle cell crisis can occur if the patient is exposed to hypoxic conditions&#44; high altitude and intense physical exercise&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Acute events include vaso-occlusive crises such as papillary necrosis of the kidney&#44; ischemic stroke and infections&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">A 59-year-old Caucasian woman presented with dark-red urine and colicky pain in the left flank&#46; She had no fever&#44; dysuria&#44; urinary urgency and no history of trauma&#44; nephrolithiasis or additional episodes of hematuria&#46; She was of Asian ascendancy and had non-consanguineous parents&#46; Her medical history was unremarkable&#44; except for hypertension&#46; Her chronic medication consisted of candesartan&#47;hydrochlorothiazide and she denied non-steroidal anti-inflammatory drugs use&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Physical examination revealed modest overweight&#44; blood pressure of 110&#47;60<span class="elsevierStyleHsp" style=""></span>mmHg&#44; no evidence of hepatosplenomegaly&#44; although left costovertebral tenderness was noted&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Laboratory tests showed normal blood cell counts&#44; coagulation parameters&#44; electrolytes&#44; and renal and hepatic tests&#46; No rhabdomyolysis nor hemolysis were present&#46; Urine dipstick revealed a specific gravity of 1&#46;010&#44; 3&#43; hemoglobin and no protein&#59; the microscopic exam showed 168 red blood cells per high power field&#44; but no casts or white blood cells&#46; Urine cultures&#44; including for mycobacteria&#44; were negative&#46; She had no anomalous cells in cytology and a normal cystoscopy&#46; A computed tomography scan &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#8211;C&#41; suggested renal papillary necrosis and excluded other abnormalities&#46; There were no criteria for diabetes mellitus&#46; Hemoglobin&#39;s electrophoresis showed the presence of an abnormal hemoglobin &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; which was subsequently documented to be HbS&#46; A molecular study revealed an heterozygosity for the hemoglobin sickle mutation of the &#946;-globin gene &#40;HBB&#58;c&#46;20A&#62;T&#41; establishing a diagnosis of SCT&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">Clinical findings resolved after conservative therapy with rest&#44; hydration and analgesia&#46; The patient was recommended to avoid circumstances that may precipitate vaso-occlusive crises&#46; Her daughter was referred for genetic testing&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">SCT is generally asymptomatic&#44; although occasionally associated with significant morbidity&#44; including papillary necrosis&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> It is a highly prevalent recessive illness&#44; mainly found in African but also in Asian populations&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> In SCT patients&#44; HbS is abnormally found with plasma concentrations typically between 35&#37; and 45&#37; of total hemoglobin&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Hematuria is the most common complication<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> of SCT&#44; but the usual etiologies&#44; such as stones&#44; urinary tract infections or neoplasms should be considered first&#46; Hence&#44; initial testing must include urine analysis&#44; culture&#44; cytology and imaging studies&#46; In SCT patients&#44; occlusion of small vessels by sickled blood cells&#44; causes microthrombi and ischaemia&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> In the kidneys&#44; this obstruction is predominantly apparent in the renal papilla due to their marginal blood supply&#46; Papillary necrosis can be difficult to diagnose&#46; The presence of sloughed papillae in the urine examination is diagnostic&#44; but has low sensitivity&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> In our patient an ultrasound and a tomography scan allowed the diagnosis&#46; Treatment is usually conservative&#44; but adjuvant therapies &#40;desmopressin or epsilon-amino caproic acid&#41; can be of benefit&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Most severe cases may require arterial embolization or surgical exploration&#46; The outcome is generally good but the patient must be informed about avoidable precipitating conditions and genetic counseling&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Hemoglobin&#39;s electrophoresis should be part of the diagnostic work-up of renal colic and&#47;or hematuria&#44; namely in patients whose etiology has never been established&#46;</p><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest related to the contents of this article&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflict of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "multimedia" => array:2 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 3651
            "Ancho" => 1667
            "Tamanyo" => 499274
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; B&#44; C&#58; Sagital&#44; coronal and axial sections of abdominal computed tomography revealing structural heterogeneity of the left renal parenquima with diminished enhancement at the tip of the medullary pyramid and the presence of small cavities filled by contrast on the borders of the small calices &#8211; aspects highly suggestive of papillary necrosis ischemia&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1417
            "Ancho" => 1667
            "Tamanyo" => 69796
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hemoglobin electrophoresis &#40;cellulose acetate&#41;&#58; amino acids substitution in hemoglobin variants alter charge and subsequently hemoglobin&#39;s mobility pattern&#46; Presence of an abnormal hemoglobin variant in Z5 region&#44; compatible with HbS &#40;<span class="elsevierStyleBold">&#42;</span>&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle cell trait and gross hematuria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46; Kiryluk"
                            1 => "A&#46; Jadoon"
                            2 => "M&#46; Gupta"
                            3 => "J&#46; Radhakrishnan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.ki.5002060"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2007"
                        "volumen" => "71"
                        "paginaInicial" => "706"
                        "paginaFinal" => "710"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17191080"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal abnormalities in sickle cell disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "T&#46;P&#46; Phuong-Thu"
                            1 => "T&#46;P&#46; Phuong-Chi"
                            2 => "H&#46;W&#46; Alan"
                            3 => "Q&#46;L&#46; Susie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1755.2000.07501.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Kidney Int"
                        "fecha" => "2000"
                        "volumen" => "57"
                        "paginaInicial" => "1"
                        "paginaFinal" => "8"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10828753"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle cell anaemia&#46; Agenda item 11&#46;4&#44; in 59th World Health Assembly&#44; 27 May 2006"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "World Health Organisation"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2006"
                        "editorial" => "World Health Organisation"
                        "editorialLocalizacion" => "Geneva&#44; Switzerland"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sickle-cell anemia&#58; a look at global haplotype distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Gabriel"
                            1 => "J&#46; Przybylski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Nat Educ"
                        "fecha" => "2010"
                        "volumen" => "3"
                        "numero" => "3"
                        "paginaInicial" => "2"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Renal papillary necrosis&#58; review and comparison of findings at multi-detector row CT and intravenous urography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Dae Chul Jung"
                            1 => "Seung Hyup Kim"
                            2 => "Jung Sung II"
                            3 => "Hwang Sung II"
                            4 => "Sun Ho Kim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/rg.266065039"
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiographics"
                        "fecha" => "2006"
                        "volumen" => "26"
                        "paginaInicial" => "1827"
                        "paginaFinal" => "1836"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17102053"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/02116995/0000003600000002/v3_201704120115/S0211699515001393/v3_201704120115/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "43981"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Cartas al Director&#58; Comentarios breves sobre casos cl&#237;nicos"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/02116995/0000003600000002/v3_201704120115/S0211699515001393/v3_201704120115/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699515001393?idApp=UINPBA000064"
]
Información del artículo
ISSN: 02116995
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 7 11 18
2024 Octubre 50 43 93
2024 Septiembre 53 26 79
2024 Agosto 56 68 124
2024 Julio 51 30 81
2024 Junio 51 36 87
2024 Mayo 72 41 113
2024 Abril 66 35 101
2024 Marzo 56 31 87
2024 Febrero 40 39 79
2024 Enero 60 27 87
2023 Diciembre 36 38 74
2023 Noviembre 40 41 81
2023 Octubre 47 35 82
2023 Septiembre 38 28 66
2023 Agosto 50 30 80
2023 Julio 66 31 97
2023 Junio 63 27 90
2023 Mayo 64 33 97
2023 Abril 31 20 51
2023 Marzo 62 36 98
2023 Febrero 38 30 68
2023 Enero 44 36 80
2022 Diciembre 85 45 130
2022 Noviembre 116 52 168
2022 Octubre 71 54 125
2022 Septiembre 51 46 97
2022 Agosto 46 69 115
2022 Julio 50 62 112
2022 Junio 38 45 83
2022 Mayo 42 45 87
2022 Abril 50 65 115
2022 Marzo 54 61 115
2022 Febrero 60 56 116
2022 Enero 52 46 98
2021 Diciembre 66 49 115
2021 Noviembre 74 49 123
2021 Octubre 55 50 105
2021 Septiembre 37 37 74
2021 Agosto 56 50 106
2021 Julio 54 46 100
2021 Junio 54 30 84
2021 Mayo 75 40 115
2021 Abril 96 77 173
2021 Marzo 105 44 149
2021 Febrero 92 42 134
2021 Enero 57 34 91
2020 Diciembre 73 25 98
2020 Noviembre 38 31 69
2020 Octubre 47 27 74
2020 Septiembre 34 24 58
2020 Agosto 55 22 77
2020 Julio 54 30 84
2020 Junio 41 23 64
2020 Mayo 43 17 60
2020 Abril 50 25 75
2020 Marzo 52 28 80
2020 Febrero 64 18 82
2020 Enero 78 33 111
2019 Diciembre 87 34 121
2019 Noviembre 77 24 101
2019 Octubre 47 19 66
2019 Septiembre 45 33 78
2019 Agosto 41 30 71
2019 Julio 69 29 98
2019 Junio 79 27 106
2019 Mayo 134 25 159
2019 Abril 197 50 247
2019 Marzo 150 29 179
2019 Febrero 82 29 111
2019 Enero 56 27 83
2018 Diciembre 167 42 209
2018 Noviembre 281 20 301
2018 Octubre 320 24 344
2018 Septiembre 140 28 168
2018 Agosto 113 76 189
2018 Julio 120 15 135
2018 Junio 119 14 133
2018 Mayo 157 15 172
2018 Abril 150 17 167
2018 Marzo 140 14 154
2018 Febrero 70 12 82
2018 Enero 59 6 65
2017 Diciembre 76 12 88
2017 Noviembre 61 14 75
2017 Octubre 62 8 70
2017 Septiembre 59 16 75
2017 Agosto 46 7 53
2017 Julio 79 15 94
2017 Junio 62 15 77
2017 Mayo 77 8 85
2017 Abril 84 22 106
2017 Marzo 86 12 98
2017 Febrero 38 12 50
2017 Enero 48 15 63
2016 Diciembre 62 14 76
2016 Noviembre 85 13 98
2016 Octubre 98 14 112
2016 Septiembre 113 5 118
2016 Agosto 127 5 132
2016 Julio 176 10 186
2016 Junio 128 0 128
2016 Mayo 202 0 202
2016 Abril 201 0 201
2016 Marzo 123 0 123
2016 Febrero 49 0 49
2016 Enero 36 0 36
2015 Diciembre 33 0 33
2015 Noviembre 43 0 43
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Nefrología
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?