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It is characterised by the presence of fibro-inflammatory tissue that surrounds the abdominal aorta and the iliac arteries<span class="elsevierStyleSup">1</span> extending to the retroperitoneal space and it covers neighbouring structures, such as ureters, causing obstructive uropathy (OU).</p><p class="elsevierStylePara">Although cases associated with multiple conditions (drugs, neoplasias, radiation and infection, amongst others) have been described, the most common cause is idiopathic.<span class="elsevierStyleSup">2</span></p><p class="elsevierStylePara">Idiopathic retroperitoneal fibrosis is more common in men aged 50-60 years old and, in most patients, it presents as non-specific lower back or abdominal pain.<span class="elsevierStyleSup">3</span></p><p class="elsevierStylePara">When the retroperitoneal tissue covers one or both ureters, potentially reversible obstructive renal failure occurs.<span class="elsevierStyleSup">1,2,4</span></p><p class="elsevierStylePara">We report the case of a patient with idiopathic retroperitoneal fibrosis that progressed to marked OU and an ultrasound showed slight unilateral dilation of the excretory system.</p><p class="elsevierStylePara">Our patient was a 54-year-old male, with no relevant personal or family history, referred by the General Practitioner due to incidental findings in the blood test of creatinine 2.74mg/dl. The patient had a history of three weeks of nausea, non-specific abdominal pain and slight testicular pain, with no other accompanying symptoms. Upon physical examination, he was normotensive and afebrile, with diuresis maintained, without macroscopic abnormalities, at around 2000ml/day.</p><p class="elsevierStylePara">In the blood test obtained from the Emergency department, the following parameters are notable: haemoglobin 15.3g/dl, leukocytes 6700/µl, platelets 305,000/µl, sodium 133mEq/l, potassium 3.6mEq/l, hepatic-pancreatic profile with no abnormalities, lactate hydrogenase 270U/l, plasma creatinine 3mg/dl, urea 116mg/dl. Urine biochemistry displayed values for sodium of 96mEq/l and potassium of 28mEq/l.</p><p class="elsevierStylePara">The renal ultrasound (Figure 1), showed normal-sized kidneys with cortical thickness maintained and we noted that the right side was larger and thicker. It showed slight dilatation of the right renal calyces (Figure 1) and no cause of dilation was seen with a bilateral positive ureteral jet on colour Doppler ultrasound.</p><p class="elsevierStylePara">Given the poor test performance with progressive deterioration of renal function, a computerised tomography (CT) scan of the abdomen was carried out (Figure 2). It revealed a large retroperitoneal mass that covered the right ureter, with the left ureter free, but on the limit of the edge of the latter, resulting in bilateral OU, although it was more pronounced on the right side. The left side only showed incipient signs of obstruction.</p><p class="elsevierStylePara">After the diagnosis, he was treated empirically with high doses of prednisone and it was decided to use bilateral double-J catheters; following this treatment immediate improvement was noted. Five days later, the patient was asymptomatic and 30 days after starting steroid treatment, plasma creatinine was 1.02mg/dl. The double-J catheters were removed 6 months after the start of treatment, with stable plasma creatinine figures being maintained.</p><p class="elsevierStylePara">This case is of interest because, in spite of being an obstructive disease, ultrasound does not make clear the cause of obstruction, and on many occasions it fails to reveal the existence of the urinary tract obstruction itself. This is due to ureteral rigidity that conditions the disease itself, preventing dilation of the ureter covered by fibro-inflammatory mass.</p><p class="elsevierStylePara">In the case that we have presented, the patient displayed a significant impairment in renal function secondary to bilateral OU (right established and left incipient), with CT being required for its diagnosis.</p><p class="elsevierStylePara">Therefore, it is necessary to evaluate the need for other imaging techniques such as CT or MRI,<span class="elsevierStyleSup">5</span> in order to diagnose this entity, since treatment started at an early stage improves the clinical profile.</p><p class="elsevierStylePara"> </p><p class="elsevierStylePara"><span class="elsevierStyleBold">Conflicts of interest</span></p><p class="elsevierStylePara"> </p><p class="elsevierStylePara">The authors declare that they have no conflicts of interest related to the contents of this article.</p><p class="elsevierStylePara"><a href="grande/11705_16025_46815_en_11705_f1.jpg" class="elsevierStyleCrossRefs"><img src="11705_16025_46815_en_11705_f1.jpg" alt="Right kidney ultrasound"></img></a></p><p class="elsevierStylePara">Figure 1. Right kidney ultrasound</p><p class="elsevierStylePara"><a href="grande/11705_16025_46816_en_11705_f2.jpg" class="elsevierStyleCrossRefs"><img src="11705_16025_46816_en_11705_f2.jpg" alt="Computerised tomography"></img></a></p><p class="elsevierStylePara">Figure 2. Computerised tomography</p>" "pdfFichero" => "P1-E550-S4088-A11705-EN.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig1" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11705_16025_46815_en_11705_f1.jpg" "Alto" => 461 "Ancho" => 658 "Tamanyo" => 67557 ] ] "descripcion" => array:1 [ "en" => "Right kidney ultrasound" ] ] 1 => array:8 [ "identificador" => "fig2" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "11705_16025_46816_en_11705_f2.jpg" "Alto" => 496 "Ancho" => 652 "Tamanyo" => 103715 ] ] "descripcion" => array:1 [ "en" => "Computerised tomography" ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Kermani TA, Crowson CS, Achenbach SJ, Luthra HS. Idiopathic retroperitoneal fibrosis: A restrospective review of clinical presentation, treatment and outcomes. Mayo Clin Proc 2011;86(4):297-303. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21454732" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Vaglio A, Salvarani C, Buzio C. Retroperitoneal fibrosis. Lancet 2006;367(9506):241-51. <a href="http://www.ncbi.nlm.nih.gov/pubmed/16427494" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "3.\u{A0}Corradi D, Maestri R, Palmisano A, Bosio S, Greco P, Manenti L, et al. Idiopathic retroperitoneal fibrosis: clinicopathologic features and differential diagnosis. Kidney Int 2007;72(6):742-53. <a href="http://www.ncbi.nlm.nih.gov/pubmed/17622270" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "4.\u{A0}Rodríguez Jornet A, Andreu Navarro FJ, Orellana Fernández R, Ibeas López J, García García M. Idiopathic retroperitoneal fibrosis: clinico-pathological characteristics. Nefrologia 2009;29(4):298-303. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19668300" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Scheel PJ Jr, Feeley N. Retroperitoneal fibrosis: the clinical, laboratory and radiographic presentation. Medicine (Baltimore) 2009;88(4):202-7." 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2020 August | 32 | 5 | 37 |
2020 July | 48 | 9 | 57 |
2020 June | 26 | 14 | 40 |
2020 May | 42 | 7 | 49 |
2020 April | 51 | 25 | 76 |
2020 March | 38 | 8 | 46 |
2020 February | 43 | 20 | 63 |
2020 January | 54 | 19 | 73 |
2019 December | 54 | 17 | 71 |
2019 November | 41 | 20 | 61 |
2019 October | 40 | 3 | 43 |
2019 September | 31 | 17 | 48 |
2019 August | 26 | 13 | 39 |
2019 July | 35 | 23 | 58 |
2019 June | 35 | 12 | 47 |
2019 May | 42 | 10 | 52 |
2019 April | 83 | 23 | 106 |
2019 March | 63 | 21 | 84 |
2019 February | 42 | 18 | 60 |
2019 January | 32 | 15 | 47 |
2018 December | 104 | 37 | 141 |
2018 November | 72 | 12 | 84 |
2018 October | 93 | 19 | 112 |
2018 September | 85 | 13 | 98 |
2018 August | 53 | 18 | 71 |
2018 July | 65 | 15 | 80 |
2018 June | 47 | 14 | 61 |
2018 May | 46 | 17 | 63 |
2018 April | 66 | 6 | 72 |
2018 March | 65 | 6 | 71 |
2018 February | 47 | 6 | 53 |
2018 January | 48 | 4 | 52 |
2017 December | 68 | 9 | 77 |
2017 November | 49 | 13 | 62 |
2017 October | 47 | 6 | 53 |
2017 September | 59 | 7 | 66 |
2017 August | 46 | 11 | 57 |
2017 July | 57 | 15 | 72 |
2017 June | 56 | 19 | 75 |
2017 May | 74 | 14 | 88 |
2017 April | 57 | 7 | 64 |
2017 March | 36 | 6 | 42 |
2017 February | 84 | 6 | 90 |
2017 January | 46 | 9 | 55 |
2016 December | 56 | 4 | 60 |
2016 November | 74 | 7 | 81 |
2016 October | 85 | 4 | 89 |
2016 September | 159 | 1 | 160 |
2016 August | 186 | 2 | 188 |
2016 July | 189 | 6 | 195 |
2016 June | 143 | 0 | 143 |
2016 May | 124 | 0 | 124 |
2016 April | 98 | 0 | 98 |
2016 March | 80 | 0 | 80 |
2016 February | 106 | 0 | 106 |
2016 January | 128 | 0 | 128 |
2015 December | 134 | 0 | 134 |
2015 November | 89 | 0 | 89 |
2015 October | 71 | 0 | 71 |
2015 September | 91 | 0 | 91 |
2015 August | 65 | 0 | 65 |
2015 July | 66 | 0 | 66 |
2015 June | 46 | 0 | 46 |
2015 May | 71 | 0 | 71 |
2015 April | 6 | 0 | 6 |