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we conducted a cross-sectional study in a population with a mean age of 83 years &#40;range&#58; 69-97 years&#41; that was recruited when patients came in for scheduled check-ups with the Geriatric Medicine and General Nephrology Departments at the General Hospital of Segovia&#46; In this group&#44; 38 patients had sCr within the normal range&#58; Group 1&#44; sCr &#8804;1&#46;1mg&#47;dl &#40;range 0&#46;7-1&#46;1&#41;&#58; 6 males and 32 females&#59; 42 had altered sCr&#46; Group 2&#44; sCr &#62;1&#46;1mg&#47;dl &#40;range 1&#46;2-3&#41;&#58; 19 males and 23 females&#46;&#160; In both groups combined&#44; 68&#46;8&#37; of the patients were female&#59; 37&#46;3&#37; of the total had diabetes mellitus&#44; and 81&#46;3&#37; had arterial hypertension&#46; GFR was estimated using the abbreviated MDRD method<span class="elsevierStyleSup">4</span> and the Cockcroft-Gault formula&#46;<span class="elsevierStyleSup">5</span></p><p class="elsevierStylePara">Table 1 shows the mean GFR given by the formulae&#44; broken down by group and sex&#46;</p><p class="elsevierStylePara">Out of the patient total&#44; 56 &#40;70&#37;&#41; had a GFR &#40;MDRD&#41; &#60;60ml&#47;min&#46; Of the patients with a GFR&#60;60ml&#47;min according to MDRD&#44; 18 had sCr within the normal range &#40;100&#37; female&#41;&#44; while 38 had a baseline sCr&#62;1&#46;1mg&#47;dl &#40;15 males &#91;39&#46;5&#37;&#93; and 23 females &#91;60&#46;5&#37;&#93;&#44; <span class="elsevierStyleItalic">P</span>&#61;&#46;001&#46;</p><p class="elsevierStylePara">The 18 patients with a normal sCr and GFR by MDRD &#60;60ml&#47;min &#40;occult renal disease&#41; had a mean age of 81&#46;33&#177;6 years&#46;</p><p class="elsevierStylePara">In our study&#44; we also found that eGFR &#40;estimated using the two methods listed here&#41; in women with sCr within the normal range was significantly lower than in men&#46; However&#44; these differences are not as pronounced in the patient group with altered sCr &#40;Group 2&#41;&#46; Our data therefore confirm a higher prevalence rate of CKD in women if they are evaluated by eGFR&#59; this statement is especially true for the subjects in Group 1&#46;</p><p class="elsevierStylePara">The differences in GFR between the sexes and study groups may lie within the mathematical formulae used to estimate GFR&#46; The mathematical formulae used in our study are based on sCr&#44; which involves the patient&#8217;s muscle mass and nutritional state&#46; Therefore&#44; these significant differences in GFR between the sexes among patients with a normal sCr are more likely to show women&#8217;s smaller muscle mass rather than their true GFR&#46; It is also important to note that the MDRD formula was designed in patients with altered renal function and not validated in a healthy population&#58; applying the MDRD formula to estimate GFR in individuals with a normal sCr may underestimate true GFR by up to 50&#37;&#46;<span class="elsevierStyleSup">6</span> On the other hand&#44; when we use the MDRD formula in patients with altered renal function&#44; the differences between males and females are less pronounced&#46; This means that the resulting eGFR may successfully show the presence of kidney disease rather than the patient&#8217;s nutritional state and&#47;or muscle mass&#46;</p><p class="elsevierStylePara">In conclusion&#44; sex is a factor to consider when checking for chronic kidney disease in the elderly&#46; The systematic use of formulae based on creatinine levels can lead to healthy elderly women being considered carriers of occult renal disease&#46;</p><p class="elsevierStylePara"><a href="grande&#47;11249&#95;16025&#95;26335&#95;en&#95;11249&#95;t1&#46;jpg" class="elsevierStyleCrossRefs"><img src="11249_16025_26335_en_11249_t1.jpg" alt="Mean estimated baseline glomerular filtration rates in the study group broken down by sex"></img></a></p><p class="elsevierStylePara">Table 1&#46; Mean estimated baseline glomerular filtration rates in the study group broken down by sex</p>"
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                  "referenciaCompleta" => "Zhang QL, Rothenbacher D. Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health 2008;8:117. <a href="http://www.ncbi.nlm.nih.gov/pubmed/18405348" target="_blank">[Pubmed]</a>"
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                  "referenciaCompleta" => "Chadban\u{A0} SJ, Briganti EM, Kerr\u{A0} PG, Dunstan DW, Welborn TA, Zimmet PZ, et al. Prevalence of kidney damage in Australian adults: The AusDiab kidney study. J Am Soc Nephrol 2003;14: S131-38."
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                  "referenciaCompleta" => "Labrador PJ, Mengotti T, Jiménez M, Macías M, Vicente F, Labrador J, et al. Insuficiencia renal oculta en Atención Primaria. ¿Un problema exclusivo de mujeres? Nefrologia 2007;27:716-20."
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                    0 => null
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                  "referenciaCompleta" => "Levey AS, Greene T, Kusek JW, Beck GJ. Simplified equation to predict glomerular filtration\u{A0} rate from serum creatinine. J Am Soc Nephrol 2000;11:828. <a href="http://www.ncbi.nlm.nih.gov/pubmed/10770960" target="_blank">[Pubmed]</a>"
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                0 => array:3 [
                  "referenciaCompleta" => "Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1244564" target="_blank">[Pubmed]</a>"
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Chronic kidney disease in the elderly: the impact of patients' sex
Enfermedad renal crónica en el anciano: influencia del género
MANUEL HERASa, Manuel Herasb, PEDRO GARCIA COSMESc, Pedro García-Cosmesd, MARIA JOSE FERNANDEZ-REYESa, M. José Fernández-Reyesb, MARIA TERESA GUERREROe, M. Teresa Guerrerof, ROSA SANCHEZa, Rosa Sánchezb
a NEFROLOGIA, HOSPITAL GENERAL DE SEGOVIA, SEGOVIA, SEGOVIA, Spain,
b Servicio de Nefrología, Hospital General de Segovia, Segovia,
c NEFROLOGIA, HOSPITAL UNIVERSITARIO DE SALAMANCA, SALAMANCA, SALAMANCA, Spain,
d Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca,
e GERIATRIA, HOSPITAL GENERAL DE SEGOVIA, SEGOVIA, SEGOVIA, Spain,
f Servicio de Geriatría, Hospital General de Segovia, Segovia,
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        "titulo" => "Enfermedad renal cr&#243;nica en el anciano&#58; influencia del g&#233;nero"
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    "textoCompleto" => "<p class="elsevierStylePara"><span class="elsevierStyleBold">To the Editor&#44;</span></p><p class="elsevierStylePara">In epidemiological studies we generally find a higher prevalence of chronic kidney disease &#40;CKD&#41; in women than in men&#44; regardless of age&#46;<span class="elsevierStyleSup">1&#44;2</span> The study by Labrador et al assesses the prevalence of occult renal disease &#40;defined as an estimated glomerular filtration rate &#40;eGFR&#41; below 60ml&#47;min and serum creatinine within the normal range&#41;&#44; and the authors found this condition in 43&#46;5&#37; of the women in a group with a mean age of 77 years&#46;<span class="elsevierStyleSup">3</span></p><p class="elsevierStylePara">We therefore propose studying sex as a factor involved in GFR in a cohort of elderly patients with both normal and altered serum creatinine &#40;sCr&#41; levels&#46; We will also analyse the effect of this factor in patients considered as carriers of occult renal disease&#46;</p><p class="elsevierStylePara">Between January and April 2006&#44; we conducted a cross-sectional study in a population with a mean age of 83 years &#40;range&#58; 69-97 years&#41; that was recruited when patients came in for scheduled check-ups with the Geriatric Medicine and General Nephrology Departments at the General Hospital of Segovia&#46; In this group&#44; 38 patients had sCr within the normal range&#58; Group 1&#44; sCr &#8804;1&#46;1mg&#47;dl &#40;range 0&#46;7-1&#46;1&#41;&#58; 6 males and 32 females&#59; 42 had altered sCr&#46; Group 2&#44; sCr &#62;1&#46;1mg&#47;dl &#40;range 1&#46;2-3&#41;&#58; 19 males and 23 females&#46;&#160; In both groups combined&#44; 68&#46;8&#37; of the patients were female&#59; 37&#46;3&#37; of the total had diabetes mellitus&#44; and 81&#46;3&#37; had arterial hypertension&#46; GFR was estimated using the abbreviated MDRD method<span class="elsevierStyleSup">4</span> and the Cockcroft-Gault formula&#46;<span class="elsevierStyleSup">5</span></p><p class="elsevierStylePara">Table 1 shows the mean GFR given by the formulae&#44; broken down by group and sex&#46;</p><p class="elsevierStylePara">Out of the patient total&#44; 56 &#40;70&#37;&#41; had a GFR &#40;MDRD&#41; &#60;60ml&#47;min&#46; Of the patients with a GFR&#60;60ml&#47;min according to MDRD&#44; 18 had sCr within the normal range &#40;100&#37; female&#41;&#44; while 38 had a baseline sCr&#62;1&#46;1mg&#47;dl &#40;15 males &#91;39&#46;5&#37;&#93; and 23 females &#91;60&#46;5&#37;&#93;&#44; <span class="elsevierStyleItalic">P</span>&#61;&#46;001&#46;</p><p class="elsevierStylePara">The 18 patients with a normal sCr and GFR by MDRD &#60;60ml&#47;min &#40;occult renal disease&#41; had a mean age of 81&#46;33&#177;6 years&#46;</p><p class="elsevierStylePara">In our study&#44; we also found that eGFR &#40;estimated using the two methods listed here&#41; in women with sCr within the normal range was significantly lower than in men&#46; However&#44; these differences are not as pronounced in the patient group with altered sCr &#40;Group 2&#41;&#46; Our data therefore confirm a higher prevalence rate of CKD in women if they are evaluated by eGFR&#59; this statement is especially true for the subjects in Group 1&#46;</p><p class="elsevierStylePara">The differences in GFR between the sexes and study groups may lie within the mathematical formulae used to estimate GFR&#46; The mathematical formulae used in our study are based on sCr&#44; which involves the patient&#8217;s muscle mass and nutritional state&#46; Therefore&#44; these significant differences in GFR between the sexes among patients with a normal sCr are more likely to show women&#8217;s smaller muscle mass rather than their true GFR&#46; It is also important to note that the MDRD formula was designed in patients with altered renal function and not validated in a healthy population&#58; applying the MDRD formula to estimate GFR in individuals with a normal sCr may underestimate true GFR by up to 50&#37;&#46;<span class="elsevierStyleSup">6</span> On the other hand&#44; when we use the MDRD formula in patients with altered renal function&#44; the differences between males and females are less pronounced&#46; This means that the resulting eGFR may successfully show the presence of kidney disease rather than the patient&#8217;s nutritional state and&#47;or muscle mass&#46;</p><p class="elsevierStylePara">In conclusion&#44; sex is a factor to consider when checking for chronic kidney disease in the elderly&#46; The systematic use of formulae based on creatinine levels can lead to healthy elderly women being considered carriers of occult renal disease&#46;</p><p class="elsevierStylePara"><a href="grande&#47;11249&#95;16025&#95;26335&#95;en&#95;11249&#95;t1&#46;jpg" class="elsevierStyleCrossRefs"><img src="11249_16025_26335_en_11249_t1.jpg" alt="Mean estimated baseline glomerular filtration rates in the study group broken down by sex"></img></a></p><p class="elsevierStylePara">Table 1&#46; Mean estimated baseline glomerular filtration rates in the study group broken down by sex</p>"
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