was read the article
array:21 [ "pii" => "X2013251409004818" "issn" => "20132514" "doi" => "10.3265/Nefrologia.2009.29.3.5101.en.full" "estado" => "S300" "fechaPublicacion" => "2009-06-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2009;29:274" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2709 "formatos" => array:3 [ "EPUB" => 211 "HTML" => 2128 "PDF" => 370 ] ] "Traduccion" => array:1 [ "es" => array:17 [ "pii" => "X0211699509004810" "issn" => "02116995" "doi" => "10.3265/Nefrologia.2009.29.3.5101.en.full" "estado" => "S300" "fechaPublicacion" => "2009-06-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia. 2009;29:274" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 6210 "formatos" => array:3 [ "EPUB" => 234 "HTML" => 5585 "PDF" => 391 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "La importancia de un diagnóstico precoz en el pronóstico de la nefritis tubulointersticial inmunoalérgica" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "274" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The importance of early diagnosis to the prognosis of immune-complex tubulointerstitial nephritis" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "T.R. Monzón Vázquez, R. Valero San Cecilio, I. Úbeda Aranda, A. Barrientos Guzmán" "autores" => array:4 [ 0 => array:2 [ "Iniciales" => "T.R." "apellidos" => "Monzón Vázquez" ] 1 => array:2 [ "Iniciales" => "R." "apellidos" => "Valero San Cecilio" ] 2 => array:2 [ "Iniciales" => "I." "apellidos" => "Úbeda Aranda" ] 3 => array:2 [ "Iniciales" => "A." "apellidos" => "Barrientos Guzmán" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "X2013251409004818" "doi" => "10.3265/Nefrologia.2009.29.3.5101.en.full" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409004818?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509004810?idApp=UINPBA000064" "url" => "/02116995/0000002900000003/v0_201502091409/X0211699509004810/v0_201502091409/es/main.assets" ] ] "itemSiguiente" => array:17 [ "pii" => "X201325140900480X" "issn" => "20132514" "doi" => "10.3265/Nefrologia.2009.29.3.4896.en.full" "estado" => "S300" "fechaPublicacion" => "2009-06-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2009;29:274-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3522 "formatos" => array:3 [ "EPUB" => 266 "HTML" => 2797 "PDF" => 459 ] ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "Atheroembolism in transplanted kidney" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "274" "paginaFinal" => "275" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ateroembolia sobre riñón trasplantado" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig1" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "18618078_f1_p275.jpg" "Alto" => 175 "Ancho" => 259 "Tamanyo" => 9240 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. Aragoncillo, M.L. Rodríguez, E. Niembro, M. Rengel, U. Verdalles, F. Anaya" "autores" => array:6 [ 0 => array:2 [ "Iniciales" => "I." "apellidos" => "Aragoncillo" ] 1 => array:2 [ "Iniciales" => "M.L." "apellidos" => "Rodríguez" ] 2 => array:2 [ "Iniciales" => "E." "apellidos" => "Niembro" ] 3 => array:2 [ "Iniciales" => "M." "apellidos" => "Rengel" ] 4 => array:2 [ "Iniciales" => "U." "apellidos" => "Verdalles" ] 5 => array:2 [ "Iniciales" => "F." "apellidos" => "Anaya" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "X0211699509004802" "doi" => "10.3265/Nefrologia.2009.29.3.4896.en.full" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509004802?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X201325140900480X?idApp=UINPBA000064" "url" => "/20132514/0000002900000003/v0_201502091629/X201325140900480X/v0_201502091629/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "X2013251409004826" "issn" => "20132514" "doi" => "10.3265/Nefrologia.2009.29.3.5259.en.full" "estado" => "S300" "fechaPublicacion" => "2009-06-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2009;29:273" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3150 "formatos" => array:3 [ "EPUB" => 239 "HTML" => 2506 "PDF" => 405 ] ] "en" => array:9 [ "idiomaDefecto" => true "titulo" => "Acute renal failure after intake of mushrooms: the orellanus syndrome" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "273" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fracaso renal agudo tras la ingestión de setas: síndrome orellánico" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Eusebio Soto Bermejo, Josep Piqueras Carrasco, José Elizalde Fernández" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Eusebio" "apellidos" => "Soto Bermejo" ] 1 => array:2 [ "nombre" => "Josep" "apellidos" => "Piqueras Carrasco" ] 2 => array:2 [ "nombre" => "José" "apellidos" => "Elizalde Fernández" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "X0211699509004829" "doi" => "10.3265/Nefrologia.2009.29.3.5259.en.full" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699509004829?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409004826?idApp=UINPBA000064" "url" => "/20132514/0000002900000003/v0_201502091629/X2013251409004826/v0_201502091629/en/main.assets" ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "The importance of early diagnosis to the prognosis of immune-complex tubulointerstitial nephritis" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "274" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "T.R. Monzón Vázquez, R. Valero San Cecilio, I. Úbeda Aranda, A. Barrientos Guzmán" "autores" => array:4 [ 0 => array:3 [ "Iniciales" => "T.R." "apellidos" => "Monzón Vázquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 1 => array:4 [ "Iniciales" => "R." "apellidos" => "Valero San Cecilio" "email" => array:1 [ 0 => "rosaliavalero@yahoo.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 2 => array:3 [ "Iniciales" => "I." "apellidos" => "Úbeda Aranda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 3 => array:3 [ "Iniciales" => "A." "apellidos" => "Barrientos Guzmán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Nefrología, Hospital Clínico San Carlos, Madrid, Madrid, España, " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La importancia de un diagnóstico precoz en el pronóstico de la nefritis tubulointersticial inmunoalérgica" ] ] "textoCompleto" => "<p class="elsevierStylePara">Dear Editor:<br></br><br></br>Immune-complex tubulointerstitial nephritis (immune-complex TIN) is a frequent disease, causing 20-40% of all cases of chronic kidney disease (CKD) and from 10 to 25% of acute renal failure (ARF).<span class="elsevierStyleSup">1</span></p><p class="elsevierStylePara">In most cases, immune-complex TIN is caused by drugs, with antibiotics being the most frequent agents.<span class="elsevierStyleSup">1</span> Allopurinol causes this type of nephritis in 1.2% of all cases.<span class="elsevierStyleSup">2 </span>Treatment consists of discontinuing the medication causing the condition<span class="elsevierStyleSup">3</span> and prescribing steroids; this last step is widely debated.<span class="elsevierStyleSup">4</span> We present the case of a woman aged 79 years with chronic arterial hypertension being treated with ARBs who received treatment with allopurinol. Two weeks after beginning this treatment, she was brought to the emergency room due to fever, general malaise and oligoanuria that had been evolving over a week, together with a diffused rash that had appeared in the previous 24 hours. Upon admission, her blood pressure was 100/50mmHg and she had foveal oedema up to the proximal ends of extremities. The analysis that was carried out showed normocytic and normochromic anaemia, eosinophilia of 767 x 103 eosinophils/ml, plasma creatinine of 8.13mg/dl, plasma urea of 203mg/dl, normal ionogram, no proteinuria and the presence of microhaematuria and eosinophilia in urine elements and sediment. Viral serology and immunology tests were negative. The abdominal Doppler ultrasound did not show pathological findings. Given a clinical profile of acute renal failure with a rash, fever and eosinophilia, together with the history of treatment with allopurinol two weeks before, the clinical diagnosis of immune-complex TIN has established; allopurinol was discontinued and steroid treatment begun (1mg/kg/day). The patient required a haemodialysis session. Subsequently, renal function underwent progressive improvement, for which reason a biopsy was not taken. The patient was discharged 10 days later with normal renal function.</p><p class="elsevierStylePara">Immune-complex TIN is frequent in clinical practice, accounting for 20-40% of cases of CKD and 10-25% of cases of acute renal failure.<span class="elsevierStyleSup">1</span> In most cases, immune-complex TIN is caused by medications.<span class="elsevierStyleSup">1</span> Its classic triad of a rash, fever and eosinophilia is only present in 10% of all cases.<span class="elsevierStyleSup">5</span> Its sure diagnosis is histological,<span class="elsevierStyleSup">1,5</span> but it was not performed in our case due to the patient’s rapid improvement. The prognosis is good if the medication is discontinued early.<span class="elsevierStyleSup">2</span> Debate exists regarding treatment with steroids,<span class="elsevierStyleSup">4</span> although numerous studies attest to the role they play in this pathology. In conclusion, we stress the importance of carrying out an exhaustive clinical history so as to be able to make the clinical diagnosis of immune-complex TIN, discontinue the medication in question at an early stage and begin steroid treatment as soon as possible, which seems to improve the patients’ renal prognosis.<br></br><br></br></p>" "pdfFichero" => "P-E-S-A185-EN.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Eknoyan G. Tubulointersticial nephropathies. In: Massry and Glassock´s (eds.). Textbook of Nephrology. 4th edition. Philadelphia: Lippincott Williams and Wilkins; 2001." "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "McInnes GT, Lawson, DH, Jick H. Acute adverse reactions attributed to allopurinol in hospitalized patients. Ann Rheum Dis 1981;40:245. <a href="http://www.ncbi.nlm.nih.gov/pubmed/7247470" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "González E. Early steroid treatment improves the recovery of renal function in patients with drug-induced acute interstitial nephritis. Kidney Int 2008;73(8):940-6. <a href="http://www.ncbi.nlm.nih.gov/pubmed/18185501" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Praga M. Response to ¿Steroid in acute interstitial nephritis¿. Kidney Int 2008;74:972-3." "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Baker RJ, Pusey CD. The changing profile of acute tubulointersticial nephritis. Nephrol Dial Transplant 2004;19:8." "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002900000003/v0_201502091629/X2013251409004818/v0_201502091629/en/main.assets" "Apartado" => array:4 [ "identificador" => "35436" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002900000003/v0_201502091629/X2013251409004818/v0_201502091629/en/P-E-S-A185-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251409004818?idApp=UINPBA000064" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 9 | 15 |
2024 October | 36 | 27 | 63 |
2024 September | 34 | 26 | 60 |
2024 August | 51 | 60 | 111 |
2024 July | 36 | 31 | 67 |
2024 June | 50 | 21 | 71 |
2024 May | 49 | 33 | 82 |
2024 April | 33 | 20 | 53 |
2024 March | 39 | 27 | 66 |
2024 February | 21 | 35 | 56 |
2024 January | 53 | 23 | 76 |
2023 December | 42 | 31 | 73 |
2023 November | 25 | 25 | 50 |
2023 October | 78 | 21 | 99 |
2023 September | 36 | 29 | 65 |
2023 August | 27 | 20 | 47 |
2023 July | 45 | 36 | 81 |
2023 June | 85 | 27 | 112 |
2023 May | 81 | 38 | 119 |
2023 April | 51 | 16 | 67 |
2023 March | 71 | 15 | 86 |
2023 February | 21 | 26 | 47 |
2023 January | 26 | 21 | 47 |
2022 December | 31 | 20 | 51 |
2022 November | 43 | 20 | 63 |
2022 October | 35 | 30 | 65 |
2022 September | 39 | 22 | 61 |
2022 August | 33 | 34 | 67 |
2022 July | 21 | 43 | 64 |
2022 June | 33 | 28 | 61 |
2022 May | 26 | 28 | 54 |
2022 April | 32 | 27 | 59 |
2022 March | 40 | 31 | 71 |
2022 February | 33 | 32 | 65 |
2022 January | 24 | 26 | 50 |
2021 December | 25 | 39 | 64 |
2021 November | 31 | 32 | 63 |
2021 October | 33 | 41 | 74 |
2021 September | 27 | 38 | 65 |
2021 August | 30 | 22 | 52 |
2021 July | 37 | 27 | 64 |
2021 June | 21 | 13 | 34 |
2021 May | 25 | 19 | 44 |
2021 April | 31 | 40 | 71 |
2021 March | 31 | 20 | 51 |
2021 February | 35 | 17 | 52 |
2021 January | 19 | 12 | 31 |
2020 December | 13 | 8 | 21 |
2020 November | 16 | 11 | 27 |
2020 October | 15 | 7 | 22 |
2020 September | 22 | 2 | 24 |
2020 August | 24 | 8 | 32 |
2020 July | 17 | 6 | 23 |
2020 June | 17 | 10 | 27 |
2020 May | 23 | 9 | 32 |
2020 April | 21 | 8 | 29 |
2020 March | 16 | 11 | 27 |
2020 February | 20 | 12 | 32 |
2020 January | 31 | 11 | 42 |
2019 December | 16 | 15 | 31 |
2019 November | 18 | 17 | 35 |
2019 October | 5 | 0 | 5 |
2019 September | 10 | 8 | 18 |
2019 August | 3 | 7 | 10 |
2019 July | 13 | 16 | 29 |
2019 June | 13 | 4 | 17 |
2019 May | 11 | 4 | 15 |
2019 April | 43 | 26 | 69 |
2019 March | 13 | 13 | 26 |
2019 February | 11 | 7 | 18 |
2019 January | 17 | 17 | 34 |
2018 December | 45 | 23 | 68 |
2018 November | 68 | 12 | 80 |
2018 October | 51 | 13 | 64 |
2018 September | 36 | 12 | 48 |
2018 August | 20 | 11 | 31 |
2018 July | 30 | 8 | 38 |
2018 June | 25 | 10 | 35 |
2018 May | 43 | 9 | 52 |
2018 April | 32 | 4 | 36 |
2018 March | 45 | 7 | 52 |
2018 February | 30 | 5 | 35 |
2018 January | 30 | 6 | 36 |
2017 December | 22 | 6 | 28 |
2017 November | 15 | 3 | 18 |
2017 October | 27 | 5 | 32 |
2017 September | 22 | 10 | 32 |
2017 August | 35 | 6 | 41 |
2017 July | 11 | 7 | 18 |
2017 June | 21 | 5 | 26 |
2017 May | 31 | 10 | 41 |
2017 April | 24 | 10 | 34 |
2017 March | 11 | 4 | 15 |
2017 February | 18 | 3 | 21 |
2017 January | 15 | 4 | 19 |
2016 December | 28 | 5 | 33 |
2016 November | 32 | 3 | 35 |
2016 October | 59 | 4 | 63 |
2016 September | 54 | 1 | 55 |
2016 August | 117 | 6 | 123 |
2016 July | 121 | 8 | 129 |
2016 June | 93 | 0 | 93 |
2016 May | 96 | 0 | 96 |
2016 April | 51 | 0 | 51 |
2016 March | 50 | 0 | 50 |
2016 February | 54 | 0 | 54 |
2016 January | 46 | 0 | 46 |
2015 December | 86 | 0 | 86 |
2015 November | 52 | 0 | 52 |
2015 October | 51 | 0 | 51 |
2015 September | 36 | 0 | 36 |
2015 August | 53 | 0 | 53 |
2015 July | 48 | 0 | 48 |
2015 June | 32 | 0 | 32 |
2015 May | 44 | 0 | 44 |
2015 April | 5 | 0 | 5 |