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Íñigo Vanrell, J. M. Gascó Company" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Aránzazu" "apellidos" => "Sastre López" "email" => array:1 [ 0 => "aranchasastre@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 1 => array:3 [ "Iniciales" => "V." "apellidos" => "Mascarós Ferrer" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 2 => array:3 [ "Iniciales" => "V." "apellidos" => "Íñigo Vanrell" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 3 => array:3 [ "Iniciales" => "J. M." "apellidos" => "Gascó Company" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Nefrología, Hospital Son Llàtzer, Palma de Mallorca, Islas Baleares, España, " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hemoperitoneo y endocarditis" ] ] "textoCompleto" => "<p class="elsevierStylePara">To the editor:</p><p class="elsevierStylePara">The incidence of hemoperitoneum in patients in dialysis varies from 6% to 57% in postmenopausal women.<span class="elsevierStyleSup">1</span> The appearance of blood in the peritoneum can be related either with renal disease and dialysis or not.</p><p class="elsevierStylePara">Libman-Sacks endocarditis was first described in 1924. It is characterized by vegetating lesions implanted on valvular surfaces and is closely related to the presence of anti-phospholipid antibodies.<span class="elsevierStyleSup">2,3</span> We report a patient in peritoneal dialysis, who developed Libman-Sacks endocarditis and hemoperitoneum.</p><p class="elsevierStylePara">The patient is a 51 year-old woman with CRF secondary to IgA mesangial nephropathy, who initiated renal replacement therapy by peritoneal dialysis in May of 2006. She had a history of natural interruption of a pregnancy on the sixth month in 1981 and thrombosis in arteriovenous fistula in 1988.</p><p class="elsevierStylePara">In August of 2006 she was admitted because of a clinical picture compatible with stroke (facial palsy and dysarthria). During the in-hospital stay an endocarditis on native aortic valve was detected y heart ultrasound. Doppler echocardiography is considered elective for the diagnosis of endocarditis. The frequency of valvular involvement is 18-50%.<span class="elsevierStyleSup">4</span> The frequency of valvular disease detection is even higher on transesophageal echocardiography.<span class="elsevierStyleSup">5</span> In the reported case thoracic echocardiography showed an enlarged vegetation emerging from the left coronary veil that caused mild aortic regurgitation (fig. 1).</p><p class="elsevierStylePara">The patient had no fever. On physical exam no cardiac murmurs were heard. Blood cultures, viral serologies, and ANA and anti- DNA antibodies were negative.Lupus anticoagulant was positive in two occasions. Cranial magnetic resonance imaging disclosed images compatible with cerebral infarctions in the frontal and left occipital lobes, and in the right cerebellar hemisphere, probably due to embolization from endocardial vegetation. The electrocardiogram showed also subendocardial ischemia probably related to microemboli. Libman-Sacks endocarditis is usually asymptomatic, although the vegetations fragments can produce distant emboli<span class="elsevierStyleSup">6</span> as in this patient. She additionally presented an isolated episode of mild hemoperitoneum in the same context as the embolisms with unremarkable ultrasound findings. The commonest causes of hemoperitoneum are: of gynecological origin, after transplantation, with catheter replacement or related to an increase in physical activity. Mild bleeding can also appear in pancreatitis, peritoneal sclerosis and after performing a colonoscopy.</p><p class="elsevierStylePara">Broad-spectrum antibiotic therapy was administered with no improvement in echocardiographic images. Anticoagulant treatment with warfarine was initiated. The hemoperitoneum was not a contraindication as it was very small.</p><p class="elsevierStylePara">The approach to the patient with valvular disease includes prophylaxis of endocarditis, anti-platelet or anticoagulant therapy, and surgical valvular replacement in selected cases with severe valvular impairment. The role of steroids in the evolution of the valvular disease is not yet completely known.<span class="elsevierStyleSup">7</span></p><p class="elsevierStylePara">We witnessed the vegetation disappearance with anticoagulant therapy on echocardiographic control.</p><p class="elsevierStylePara">In this case, the natural pregnancy interruption, the history of thrombosis, the positive lupus anticoagulant and the excellent evolution with anticoagulant therapy would confirm thise infrequent diagnosis. </p>" "pdfFichero" => "P-E-S-A10017-EN.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:4 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438795" "palabras" => array:1 [ 0 => "Hemoperitoneo" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438797" "palabras" => array:1 [ 0 => "Endocarditis" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438799" "palabras" => array:1 [ 0 => "Diálisis peritoneal" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec438801" "palabras" => array:1 [ 0 => "Síndrome antifosfolípido" ] ] ] "en" => array:4 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438796" "palabras" => array:1 [ 0 => "Hemoperitoneum" ] ] 1 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438798" "palabras" => array:1 [ 0 => "Endocarditis" ] ] 2 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438800" "palabras" => array:1 [ 0 => "Peritoneal dialysis" ] ] 3 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec438802" "palabras" => array:1 [ 0 => "Antiphospholipid syndrome" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "La incidencia de hemoperitoneo en diálisis varia del 6% hasta el 57% en mujeres premenopáusicas. El sangrado peritoneal puede ser el resultado de un proceso relacionado con la diálisis o no estar relacionado con la enfermedad renal. La endocarditis de Libman- Sacks se describió por primera vez en 1924, se caracteriza por lesiones de tipo verrugoso implantadas en las superficies valvulares y está íntimamente ligada a la presencia de anticuerpos antifosfolípido. Enviamos el caso de una paciente en programa de Diálisis peritoneal que presentó una endocarditis de Libman-Sacks, y cursó con hemoperitoneo." ] "en" => array:1 [ "resumen" => "The incidence of hemoperitoneum varies from 6% to 57% in premenopausal women. Bloody peritoneal dialysate may be the result of the peritoneal dialysis procedure or may be due to factors unrelated to renal disease. The Libman-Sacks endocarditis was described for the first time in 1924, is characterized for verrucous lesions in the surfaces valves and has been intimately associated with the presence of antiphospholipid antibodies. We send a case of a patient in program of Dialysis peritoneal that presented an Libman-Sacks endocarditis and hemoperitoneum." ] ] "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Greenberg A, Bernardini J, Piraino BM y cols. Hemoperitoneum complicating chronic peritoneal dialysis: single-center experience and literature review. Am J Kidney Dis 19: 252, 1992. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1553970" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Turiel M, Sarzi-Puttini P, Peretti R, Bonizzato S, Muzzupappa S, Atzeni F, Rossi E, Doria A. 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Arthritis Rheum 54:3918, 2006. <a href="http://www.ncbi.nlm.nih.gov/pubmed/17133599" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Cervera R, Font J, Paré C, Azqueta M, Pérez-Villa F, López-Soto A, Ingelmo M. Cardiac disease in sistemic lupus erithematosus: prospective study of 70 patients. Ann Rheum Dis 51: 156-9, 1992. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1550395" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Roldan CA, Shivaly BK, Lau CC, Gurule FT, Smith EA, Crawford MH. Systemic lupus erithematosus valve disease by transesophageal echocardiografhy and the role of antiphospholipid antibodies. J Am Coll Cardiol 20: 1127-34, 1992. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1341885" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Roldan CA. Valvular disease associated with systemic illnes. Cardiol Clin 16: 531, 1998. <a href="http://www.ncbi.nlm.nih.gov/pubmed/9742329" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:3 [ "referenciaCompleta" => "Fluture A, Chaudhari S, Frishman WH. Valvular heart disease and systemic lupus erythematosus: therapeutic implications. Heart Dis 5: 349-53, 2003. <a href="http://www.ncbi.nlm.nih.gov/pubmed/14503933" target="_blank">[Pubmed]</a>" "contribucion" => array:1 [ 0 => null ] "host" => array:1 [ 0 => null ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002800000001/v0_201502091616/X2013251408033276/v0_201502091617/en/main.assets" "Apartado" => array:4 [ "identificador" => "35436" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002800000001/v0_201502091616/X2013251408033276/v0_201502091617/en/P-E-S-A10017-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408033276?idApp=UINPBA000064" ]
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2015 June | 36 | 0 | 36 |
2015 May | 49 | 0 | 49 |
2015 April | 12 | 0 | 12 |