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    "textoCompleto" => "<p class="elsevierStylePara">To the editor&#58;</p><p class="elsevierStylePara">Waldenstr&#246;m&#191;s macroglobulinemia &#40;WM&#41; is a lymphoproliferative disease characterized by the secretion of an IgM type monoclonal immunoglobulin&#46; It occurs in patients with ymphoplasmocytic lymphoma and also in patients with other small B cell lymphomas&#46; Typically&#44; there is a lymphoplasmocytic infiltration of the bone marrow&#44; lymph nodes&#44; spleen&#44; and occasionally of other tissues and organs like the kidney&#46; Whether lymphoplasmocytic lymphoma and WM are the same condition is subject to controversy&#46;<span class="elsevierStyleSup">1&#44;2</span></p><p class="elsevierStylePara">Renal disease is basically due to IgM depositions in glomerular basal membrane and renal infiltration with lymphocytes or plasmacytoid cells&#46;<span class="elsevierStyleSup">3</span> Despite this&#44; renal failure is infrequent&#46;</p><p class="elsevierStylePara">We present a 74 year-old male who was admitted to the Nephrology Department with a diagnosis of exacerbated chronic renal failure that required emergency hemodialysis&#46; He went to the Hospital because of malaise&#44; asthenia&#44; diarrhea and nausea in the last five months&#46; He had been evaluated at the Gastroenterology Department for 3 months and the creatinine value was 2 mg&#47;dL&#46; On physical exam he was pale&#44; had cardiac arrhythmia&#44; basal pulmonary hypoventilation&#44; jugular ingurgitation&#44; hepatomegaly&#44; and edemas in both legs&#46; In blood analysis anemia&#44; thrombocytopenia&#44; nitrogen retention &#40;Creatinine 13 mg&#47;dL&#41; and metabolic acidosis were detected&#46; ESR&#44; IgM gammaglobulin and Kappa chains values were also elevated&#46; A &#171;rouleaux&#187; phenomenon was seen&#46; In urine there was no excretion of light chains&#46; Bone marrow aspirate and biopsy disclosed infiltration of lymphocytes with plasmacytoid differentiation&#46; The immunological study by means of flow cytometry was compatible with lymphoplasmocytic lymphoma&#46; Renal biopsy showed&#58; 22 histologically normal glomeruli and 3 sclerosed glomeruli&#46; There was infiltration of the interstitium with small size atypical lymphocytes&#44; plasmacytoid lymphocytes and plasma cells&#44; which markedly widened the renal interstitium &#40;fig&#46; 1&#41;&#46; By immunohistochemistry malignant cells were found to be positive for anti-CD20 and anti-CD3 anti-sera&#46;</p><p class="elsevierStylePara">The etiology of WM is unknown but somatic mutations and chromosomal abnormalities of malignant B cell are present&#46; Surface antigens expressed in atypical lymphocyte are mainly CD19&#44; CD20&#44; CD24 and light chain kappa&#46;<span class="elsevierStyleSup">4</span> The clinical picture is similar to other malignant conditions with general syndrome&#44; night sweating&#44; fever&#44; together with symptoms derived from organ involvement due to tumoral infiltration&#44; IgM or amyloid protein deposition or hyperviscosity syndrome&#46;<span class="elsevierStyleSup">1&#44;3&#44;5</span> The following renal manifestations have been described&#58; glomerulonephritis&#44; due to IgM or cryoglobulins depositions and nephrotic syndrome&#44; commonly secondary to amyloidosis or to IgM thrombi within the glomerular capillaries&#46;<span class="elsevierStyleSup">6-9</span></p><p class="elsevierStylePara">In the reported case&#44; the patient presented with general and digestive symptoms&#44; and renal failure without proteinuria&#44; which prompted the decision to perform a renal biopsy&#46; The pathological examination of the sample revealed interstitial renal infiltration with lymphoplasmocytic lymphoma with no IgM depositions&#46;</p><p class="elsevierStylePara">We consider that this case is interesting because of the presence of renal failure&#44; which is infrequent in this condition&#44; and also because of the lack of proteinuria&#44; probably due to lymphocytic infiltration of the interstitium that did not affect the glomeruli&#46;</p><p class="elsevierStylePara">The patient initiated chemotherapy with chlorambucil and prednisone and he was maintained in on chronic hemodialysis until he died nine months after the diagnosis&#46; </p>"
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                  "referenciaCompleta" => "Pangalis GA, Kyrtsonis MC, Kontopidou FN, Vassilakopoulos TP. Differential diagnosis of Waldenstrom´s macroglobulinemia from other low-grade B-cell lymphoproliferative disorders. Semin Oncol 30 (2): 201-205, 2003. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12720136" target="_blank">[Pubmed]</a>"
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                  "referenciaCompleta" => "Berger F, Traverse-Glehen A, Felman P, Callet- Bauchu E. Clinicopathologic features of Waldenstrom´s macroglobulinemia and marginal zone lymphoma: are they distinct or the same entity? Clin Lymphoma 5 (4): 220-224, 2005. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15794852" target="_blank">[Pubmed]</a>"
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                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Veltman GA, Van Veen S, Kluin-Nelemans JC, Bruijn JA. Renal disease in Wadenström ´s macroglobulinemia. Nephrol Dial Transplant 12: 1256-1259, 1997. <a href="http://www.ncbi.nlm.nih.gov/pubmed/9198063" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
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              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Jensen GS, Andrews EJ, Mant MJ, Vergidis R. Transitions in CD45 isoform expression indicate continuous differentiation of a monoclonal CD5 CD11b B lineage in Waldenstrom´s macroglobulinemia. Am J Hematol 37 (1): 20-30, 1991. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1708944" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
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              ]
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                0 => array:3 [
                  "referenciaCompleta" => "Dimopoulos MA, Panayiotidis P, Moulopoulos LA, Sfikakis P. Waldenstrom´s macroglobulinemia: clinical features, complications and management. J Clin Oncol 18 (1): 214-226, 2000. <a href="http://www.ncbi.nlm.nih.gov/pubmed/10623712" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
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            ]
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              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Isaac J, Herrera GA. Cast nephropathy in a case of Waldenstrom´s macroglobulinemia. Nephron 91 (3): 512-515, 2002. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12119489" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
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                0 => array:3 [
                  "referenciaCompleta" => "Harada Y, Ido N, Okada T, Otani M. Nephrotic síndrome caused by protein thrombi in glomerulocapillary lumen in Waldenstrom ´s macroglobulinemia. Br J Haematol 110 (4): 880-883, 2000. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11054074" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
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              "identificador" => "bib8"
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              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Haraguchi S, Tomiyoshi Y, Aoki S, Sakemi T. Nephrotic syndrome due to immunologically mediated hypocomplementic glomerulonephritis in a patient of Waldenstrom´s macroglobulinemia. Nephron 92 (2): 452-455, 2002. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12218329" target="_blank">[Pubmed]</a>"
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                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Muso E, Tamura I, Yashiro M, Asaka Y. Waldenstrom ´s macroglobulinemia associated with amyloidosis and membranous nephropathy. Nippon Jinzo Gakkai Shi 35 (11): 1265-1269, 1993. <a href="http://www.ncbi.nlm.nih.gov/pubmed/8139140" target="_blank">[Pubmed]</a>"
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Renal failure secondary to lymphoplasmocytic lymphoma- Waldenström's macroglobulinemia
Insuficiencia renal secundaria a linfoma linfoplasmocíticomacroglobulinemia de Waldenstrom
Elena Jiménez Víboraa, A. I.. Martínez Puertoa, J. A.. Milán Martína, J. R.. Armas Padróna
a Servicio de Nefrología. Servicio de Anatomía Patológica, Hospital Universitario Virgen Macarena, Sevilla, Sevilla, España,
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    "textoCompleto" => "<p class="elsevierStylePara">To the editor&#58;</p><p class="elsevierStylePara">Waldenstr&#246;m&#191;s macroglobulinemia &#40;WM&#41; is a lymphoproliferative disease characterized by the secretion of an IgM type monoclonal immunoglobulin&#46; It occurs in patients with ymphoplasmocytic lymphoma and also in patients with other small B cell lymphomas&#46; Typically&#44; there is a lymphoplasmocytic infiltration of the bone marrow&#44; lymph nodes&#44; spleen&#44; and occasionally of other tissues and organs like the kidney&#46; Whether lymphoplasmocytic lymphoma and WM are the same condition is subject to controversy&#46;<span class="elsevierStyleSup">1&#44;2</span></p><p class="elsevierStylePara">Renal disease is basically due to IgM depositions in glomerular basal membrane and renal infiltration with lymphocytes or plasmacytoid cells&#46;<span class="elsevierStyleSup">3</span> Despite this&#44; renal failure is infrequent&#46;</p><p class="elsevierStylePara">We present a 74 year-old male who was admitted to the Nephrology Department with a diagnosis of exacerbated chronic renal failure that required emergency hemodialysis&#46; He went to the Hospital because of malaise&#44; asthenia&#44; diarrhea and nausea in the last five months&#46; He had been evaluated at the Gastroenterology Department for 3 months and the creatinine value was 2 mg&#47;dL&#46; On physical exam he was pale&#44; had cardiac arrhythmia&#44; basal pulmonary hypoventilation&#44; jugular ingurgitation&#44; hepatomegaly&#44; and edemas in both legs&#46; In blood analysis anemia&#44; thrombocytopenia&#44; nitrogen retention &#40;Creatinine 13 mg&#47;dL&#41; and metabolic acidosis were detected&#46; ESR&#44; IgM gammaglobulin and Kappa chains values were also elevated&#46; A &#171;rouleaux&#187; phenomenon was seen&#46; In urine there was no excretion of light chains&#46; Bone marrow aspirate and biopsy disclosed infiltration of lymphocytes with plasmacytoid differentiation&#46; The immunological study by means of flow cytometry was compatible with lymphoplasmocytic lymphoma&#46; Renal biopsy showed&#58; 22 histologically normal glomeruli and 3 sclerosed glomeruli&#46; There was infiltration of the interstitium with small size atypical lymphocytes&#44; plasmacytoid lymphocytes and plasma cells&#44; which markedly widened the renal interstitium &#40;fig&#46; 1&#41;&#46; By immunohistochemistry malignant cells were found to be positive for anti-CD20 and anti-CD3 anti-sera&#46;</p><p class="elsevierStylePara">The etiology of WM is unknown but somatic mutations and chromosomal abnormalities of malignant B cell are present&#46; Surface antigens expressed in atypical lymphocyte are mainly CD19&#44; CD20&#44; CD24 and light chain kappa&#46;<span class="elsevierStyleSup">4</span> The clinical picture is similar to other malignant conditions with general syndrome&#44; night sweating&#44; fever&#44; together with symptoms derived from organ involvement due to tumoral infiltration&#44; IgM or amyloid protein deposition or hyperviscosity syndrome&#46;<span class="elsevierStyleSup">1&#44;3&#44;5</span> The following renal manifestations have been described&#58; glomerulonephritis&#44; due to IgM or cryoglobulins depositions and nephrotic syndrome&#44; commonly secondary to amyloidosis or to IgM thrombi within the glomerular capillaries&#46;<span class="elsevierStyleSup">6-9</span></p><p class="elsevierStylePara">In the reported case&#44; the patient presented with general and digestive symptoms&#44; and renal failure without proteinuria&#44; which prompted the decision to perform a renal biopsy&#46; The pathological examination of the sample revealed interstitial renal infiltration with lymphoplasmocytic lymphoma with no IgM depositions&#46;</p><p class="elsevierStylePara">We consider that this case is interesting because of the presence of renal failure&#44; which is infrequent in this condition&#44; and also because of the lack of proteinuria&#44; probably due to lymphocytic infiltration of the interstitium that did not affect the glomeruli&#46;</p><p class="elsevierStylePara">The patient initiated chemotherapy with chlorambucil and prednisone and he was maintained in on chronic hemodialysis until he died nine months after the diagnosis&#46; </p>"
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                  "referenciaCompleta" => "Pangalis GA, Kyrtsonis MC, Kontopidou FN, Vassilakopoulos TP. Differential diagnosis of Waldenstrom´s macroglobulinemia from other low-grade B-cell lymphoproliferative disorders. Semin Oncol 30 (2): 201-205, 2003. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12720136" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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                  "referenciaCompleta" => "Berger F, Traverse-Glehen A, Felman P, Callet- Bauchu E. Clinicopathologic features of Waldenstrom´s macroglobulinemia and marginal zone lymphoma: are they distinct or the same entity? Clin Lymphoma 5 (4): 220-224, 2005. <a href="http://www.ncbi.nlm.nih.gov/pubmed/15794852" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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              "identificador" => "bib3"
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                0 => array:3 [
                  "referenciaCompleta" => "Veltman GA, Van Veen S, Kluin-Nelemans JC, Bruijn JA. Renal disease in Wadenström ´s macroglobulinemia. Nephrol Dial Transplant 12: 1256-1259, 1997. <a href="http://www.ncbi.nlm.nih.gov/pubmed/9198063" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
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            ]
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              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Jensen GS, Andrews EJ, Mant MJ, Vergidis R. Transitions in CD45 isoform expression indicate continuous differentiation of a monoclonal CD5 CD11b B lineage in Waldenstrom´s macroglobulinemia. Am J Hematol 37 (1): 20-30, 1991. <a href="http://www.ncbi.nlm.nih.gov/pubmed/1708944" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
                  "host" => array:1 [
                    0 => null
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            ]
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              "identificador" => "bib5"
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              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Dimopoulos MA, Panayiotidis P, Moulopoulos LA, Sfikakis P. Waldenstrom´s macroglobulinemia: clinical features, complications and management. J Clin Oncol 18 (1): 214-226, 2000. <a href="http://www.ncbi.nlm.nih.gov/pubmed/10623712" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:3 [
                  "referenciaCompleta" => "Isaac J, Herrera GA. Cast nephropathy in a case of Waldenstrom´s macroglobulinemia. Nephron 91 (3): 512-515, 2002. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12119489" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
                  ]
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              "identificador" => "bib7"
              "etiqueta" => "7"
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                0 => array:3 [
                  "referenciaCompleta" => "Harada Y, Ido N, Okada T, Otani M. Nephrotic síndrome caused by protein thrombi in glomerulocapillary lumen in Waldenstrom ´s macroglobulinemia. Br J Haematol 110 (4): 880-883, 2000. <a href="http://www.ncbi.nlm.nih.gov/pubmed/11054074" target="_blank">[Pubmed]</a>"
                  "contribucion" => array:1 [
                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Haraguchi S, Tomiyoshi Y, Aoki S, Sakemi T. Nephrotic syndrome due to immunologically mediated hypocomplementic glomerulonephritis in a patient of Waldenstrom´s macroglobulinemia. Nephron 92 (2): 452-455, 2002. <a href="http://www.ncbi.nlm.nih.gov/pubmed/12218329" target="_blank">[Pubmed]</a>"
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                    0 => null
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                0 => array:3 [
                  "referenciaCompleta" => "Muso E, Tamura I, Yashiro M, Asaka Y. Waldenstrom ´s macroglobulinemia associated with amyloidosis and membranous nephropathy. Nippon Jinzo Gakkai Shi 35 (11): 1265-1269, 1993. <a href="http://www.ncbi.nlm.nih.gov/pubmed/8139140" target="_blank">[Pubmed]</a>"
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Article information
ISSN: 20132514
Original language: English
DOI:
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