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Torregrosa Prats" "autores" => array:1 [ 0 => array:1 [ "nombre" => "V. Torregrosa Prats" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:8 [ "pii" => "X0211699508032583" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508032583?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408032580?idApp=UINPBA000064" "url" => "/20132514/00000028000000S5/v0_201502091603/X2013251408032580/v0_201502091603/en/main.assets" ] "itemAnterior" => array:16 [ "pii" => "X2013251408032603" "issn" => "20132514" "estado" => "S300" "fechaPublicacion" => "2008-10-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2008;28 Supl 5:3-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1725 "formatos" => array:3 [ "EPUB" => 206 "HTML" => 1247 "PDF" => 272 ] ] "en" => array:8 [ "idiomaDefecto" => true "titulo" => "The challenge of hyperphosphatemia control in chronic kidney disease" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "3" "paginaFinal" => "6" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El reto del control de la hiperfosfatemia en la enfermedad renal crónica" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "V. Lorenzo Sellares" "autores" => array:1 [ 0 => array:1 [ "nombre" => "V. Lorenzo Sellares" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:8 [ "pii" => "X0211699508032606" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508032606?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408032603?idApp=UINPBA000064" "url" => "/20132514/00000028000000S5/v0_201502091603/X2013251408032603/v0_201502091603/en/main.assets" ] "en" => array:9 [ "idiomaDefecto" => true "titulo" => "Introduction to lanthanum carbonate: pharmacology, safety and tolerability" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "7" "paginaFinal" => "10" ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Rodríguez Portillo" "autores" => array:1 [ 0 => array:1 [ "nombre" => "M. Rodríguez Portillo" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Introducción al carbonato de Lantano; farmacología, seguridad y tolerabilidad" ] ] "tienePdf" => false "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "Se describen varios aspectos de Fosrenol® (carbonato de lantano), que se pueden resumir como sigue: El lantano tiene gran afinidad de unión por el fosfato. Su absorción en el intestino es mínima y se elimina por la bilis, por lo que la insuficiencia renal no favorece la acumulación de lantano en el organismo. En ensayos clínicos realizados con más de 5.500 pacientes se ha demostrado que Fosrenol® es eficaz y seguro. En estudios a corto y largo plazo (de 6 años de duración) se ha comprobado que Fosrenol® es eficaz para controlar el fosfato sérico. El lantano no se acumula en el frente de mineralización del hueso y no disminuye el recambio óseo. El lantano no se encuentra en el sistema nervioso central. La presencia de lantano en el hígado se explica por el hecho de que la cantidad mínima de lantano que se absorbe tiene que eliminarse a través del hígado." ] "en" => array:1 [ "resumen" => "The present report describes different aspects of Fosrenol® (lantahnum carbonate) which can be summarized as follows: Lanthanum shows a great binding affinity for phosphate. It is minimally absorbed by intestine and is eliminated by biliary route thus renal failure does not favour body accumulation of lanthanum. The effectiveness and safety of Fosrenol® has been proven in clinical trials which have include more of 5,500 patients. Fosrenol ® has shown to be effective in controlling serum phosphate in short and long term studies (6 years). Lanthanum does not accumulate in the bone mineralization front and does not produce low bone turnover. Lanthanum is not found in the central nervous system. The presence of lanthanum in liver is explained by the fact that the minimal amount of lanthanum absorbed has to be disposed through liver." ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/00000028000000S5/v0_201502091603/X2013251408032599/v0_201502091603/en/main.assets" "Apartado" => null "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408032599?idApp=UINPBA000064" ]
Original language: English
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