array:21 [
  "pii" => "X2013251408005415"
  "issn" => "20132514"
  "doi" => " "
  "estado" => "S300"
  "fechaPublicacion" => "2008-08-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia (English Version). 2008;28:439-46"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4395
    "formatos" => array:3 [
      "EPUB" => 279
      "HTML" => 3088
      "PDF" => 1028
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699508005418"
      "issn" => "02116995"
      "doi" => " "
      "estado" => "S300"
      "fechaPublicacion" => "2008-08-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2008;28:439-46"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 25912
        "formatos" => array:3 [
          "EPUB" => 278
          "HTML" => 24321
          "PDF" => 1313
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "titulo" => "FACTORES PRONOSTICOS DE SUPERVIVENCIA RENAL EN GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA PRIMARIA"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "439"
            "paginaFinal" => "446"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Factors predicting for renal survival in primary focal segmental glomerulosclerosis"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jorge Rojas Rivera, Milagros Pérez, Abdías Hurtado, Carmen Asato"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Jorge"
                "apellidos" => "Rojas Rivera"
              ]
              1 => array:2 [
                "nombre" => "Milagros"
                "apellidos" => "Pérez"
              ]
              2 => array:2 [
                "nombre" => "Abdías"
                "apellidos" => "Hurtado"
              ]
              3 => array:2 [
                "nombre" => "Carmen"
                "apellidos" => "Asato"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251408005415"
          "doi" => " "
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005415?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508005418?idApp=UINPBA000064"
      "url" => "/02116995/0000002800000004/v0_201502091416/X0211699508005418/v0_201502091417/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251408005407"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-08-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2008;28:447-52"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5617
      "formatos" => array:3 [
        "EPUB" => 283
        "HTML" => 4576
        "PDF" => 758
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "Measurement of vascular access blood flow rate during hemodialysis in 38 patients using the thermodilution technique. A comparative study with the Delta-H method"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "447"
          "paginaFinal" => "452"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Exploración funcional del acceso vascular durante la hemodiálisis en 38 pacientes mediante la técnica de termodilución. Estudio comparativo con el método Delta-H."
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ramon Roca-Tey, Rosa Samon, Omar Ibrik, Isabel Giménez, Jordi Viladoms"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Ramon"
              "apellidos" => "Roca-Tey"
            ]
            1 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Samon"
            ]
            2 => array:2 [
              "nombre" => "Omar"
              "apellidos" => "Ibrik"
            ]
            3 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Giménez"
            ]
            4 => array:2 [
              "nombre" => "Jordi"
              "apellidos" => "Viladoms"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X021169950800540X"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X021169950800540X?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005407?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005407/v0_201502091636/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251408005423"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-08-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia (English Version). 2008;28:433-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4603
      "formatos" => array:3 [
        "EPUB" => 290
        "HTML" => 3568
        "PDF" => 745
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "On-line sequential hemodiafiltration (OL-S-HDF): a new therapeutic option"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "433"
          "paginaFinal" => "438"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "HEMODIAFILTRACION EN LINEA SECUENCIAL (HDF-OL-S): Una nueva opción terapéutica."
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Julia Kanter, Marta Puerta Carretero, Rafael Perez García, Juan Manuel López Gómez, Rosa Jofré, Patrocinio Rodríguez Benitez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Julia"
              "apellidos" => "Kanter"
            ]
            1 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Puerta Carretero"
            ]
            2 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Perez García"
            ]
            3 => array:2 [
              "nombre" => "Juan Manuel"
              "apellidos" => "López Gómez"
            ]
            4 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Jofré"
            ]
            5 => array:2 [
              "nombre" => "Patrocinio"
              "apellidos" => "Rodríguez Benitez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699508005426"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508005426?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005423?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005423/v0_201502091636/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "titulo" => "Factors predicting for renal survival in primary focal segmental glomerulosclerosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "439"
        "paginaFinal" => "446"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Jorge Rojas Rivera, Milagros Pérez, Abdías Hurtado, Carmen Asato"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Jorge"
            "apellidos" => "Rojas Rivera"
            "email" => array:1 [
              0 => "jerori2003@yahoo.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Milagros"
            "apellidos" => "P&#233;rez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Abd&#237;as"
            "apellidos" => "Hurtado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Carmen"
            "apellidos" => "Asato"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "affb"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrología Hospital Nacional Arzobispo Loayza y Universidad Peruana Cayetano Heredia, Lima, Lima, Perú, "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Patología Quirúrgica, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Perú, "
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "affb"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "FACTORES PRONOSTICOS DE SUPERVIVENCIA RENAL EN GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA PRIMARIA"
      ]
    ]
    "textoCompleto" => "INTRODUCTION <br />Focal segmental glomerulosclerosis &#40;FSGS&#41; is a clinical and pathological syndrome characterized by proteinuria and segmental sclerosis of some glomeruli&#44; with fusion of podocyte processes&#46; Obliteration of glomeruli by cell proliferation or accumulation of extracellular collagen matrix may occur&#46;1 FSGS is classified as primary in the absence of an underlying disease&#46; Clinical signs of FSGS are variable&#44; but most patients have proteinuria in the nephrotic range&#44; arterial hypertension &#40;AHT&#41;&#44; and some grade of kidney function impairment&#46;2 Primary FSGS has a variable prognosis depending on the ethnic&#44; clinical&#44; and histopathological characteristics&#44; treatment scheme&#44; <br />treatment response&#44; and the different observation periods&#46; There is however agreement in that patients with the collapsing and cellular histological variants have a poorer prognosis and experience a relatively rapid kidney function impairment&#46; 3-6 Clinically&#44; it is estimated that 50&#37; of patients with persistent proteinuria in the nephrotic range will progress to end-stage renal disease &#40;ESRD&#41; within 5-10 years&#46; Untreated patients have a poor prognosis&#44; reaching the end stage within 3-6 years&#46;7&#44;8 <br /> <br />An increasing incidence of primary FSGS has been reported in several countries&#46; In the United States&#44; FSGS is the <br />most common cause of nephrotic syndrome and ESRD in black and white adults with primary glomerulonephritis&#46;9-11 A similar trend has been noted in Latin America&#46;12-14 In Peru&#44; FSGS has displaced membranoproliferative glomerulonephritis as the most common primary glomerulonephritis&#46;15&#44;16 However&#44; recent European studies do not show this trend&#46; Thus&#44; in Spain&#44; the glomerulonephritis registry of the SEN17 showed no changes in incidence between 1994 and 2005&#46; Similarly&#44; Cameron18 found no differences in London in the 1970-2000&#44; during which the incidence rate remained at 20&#37;&#46; In Italy&#44;19 incidence changed from 11&#46;7&#37; to 10&#46;4&#37; from 1987 to 1993&#46; Few studies have been conducted in Peru on primary FSGS&#44; and because of its epidemiological significance and its risk of progressing to ESRD&#44; a search was made for clinical and histological factors having a prognostic value in the evolution of kidney function and that would allow for implementing a rational and appropriate therapeutic approach based on current evidence&#46; <br /> <br />PATIENTS AND METHODS <br /> <br />Study design and population <br />A longitudinal&#44; retrospective study was conducted on a historical cohort of patients diagnosed whit primary FSGS based on a kidney biopsy who attended the department of nephrology of Hospital Nacional Arzobispo Loayza from January 1994 to December 2004&#46; Medical records and pathology reports of patients were reviewed&#44; and their demographic&#44; clinical&#44; laboratory&#44; and histological data were recorded at the time of kidney biopsy&#46; Among 64 patients with a histological diagnosis of FSGS&#44; 51 patients had primary FSGS&#46; Clinical follow-up and home visit were performed in 44 patients &#40;86&#46;3&#37;&#41;&#44; while the remaining 7 patients moved and could not be located&#46; These 44 patients formed the final analysis sample&#46; Patients older than 15 years with a diagnosis of primary FSGS&#44; a renal <br />biopsy sample with 8 or more glomeruli&#44; and light microscopy and immunofluorescence studies were enrolled into the study&#46; Patients with concomitant nephropathy&#44; obesity &"
    "pdfFichero" => "P-E-S-A391-EN.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:4 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440847"
          "palabras" => array:1 [
            0 => "s&#237;ndrome nefr&#243;tico"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440849"
          "palabras" => array:1 [
            0 => "Glomeruloesclerosis focal y segmentaria"
          ]
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440851"
          "palabras" => array:1 [
            0 => "insuficiencia renal"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440853"
          "palabras" => array:1 [
            0 => "supervivencia renal"
          ]
        ]
      ]
      "en" => array:4 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440848"
          "palabras" => array:1 [
            0 => "nephrotic syndrome"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440850"
          "palabras" => array:1 [
            0 => "Focal segmental glomerulosclerosis"
          ]
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440852"
          "palabras" => array:1 [
            0 => "renal failure"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440854"
          "palabras" => array:1 [
            0 => "renal survival"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "Introducci&#243;n&#58; En Per&#250; la incidencia de glomeruloesclerosis focal y segmentaria primaria ha aumentado considerablemente durante la &#250;ltima d&#233;cada y actualmente es la primera causa de glomerulonefritis primaria en adultos&#46; Por su prevalencia y alta probabilidad de progresar a insuficiencia renal cr&#243;nica terminal&#44; se buscaron factores con valor pron&#243;stico para supervivencia renal y remisi&#243;n de proteinuria&#46; Pacientes y M&#233;todos&#58; Cohorte hist&#243;rica de 44 pacientes&#46; Estudiamos las caracter&#237;sticas cl&#237;nicas e histol&#243;gicas al momento de la biopsia renal y la funci&#243;n renal al seguimiento&#46; Los desenlaces principales fueron&#58; deterioro renal &#40;incremento de creatinina &#62;50&#37; y&#47;o insuficiencia renal terminal&#41; y remisi&#243;n de proteinuria &#40;parcial 0&#46;3-3&#46;49 g&#47;d&#237;a y completa &#60; 0&#46;3g&#47;d&#237;a&#41;&#46; Se usaron curvas de Kaplan-Meier y regresi&#243;n multivariable de Cox&#46; Resultados&#58; El 59&#37; de los pacientes fueron varones&#46; El 54&#46;5&#37; present&#243; insuficiencia renal&#44; 53&#46;5&#37; s&#237;ndrome nefr&#243;tico y 43&#46;2&#37; hipertensi&#243;n arterial al momento de la biopsia&#46; Los tipos histol&#243;gicos fueron&#58; no especificado 75&#37;&#44; celular 13&#46;6&#37;&#44; tip 6&#46;8&#37; e hiliar 4&#46;5&#37;&#46; El 56&#46;8&#37; recibi&#243; esteroides por 6&#46;2 &#177; 4&#46;1 meses y el 32&#37; fue corticodependiente&#46; La funci&#243;n renal empeor&#243; en el 18&#46;2&#37;&#46; El 37&#46;8&#37; logr&#243; remisi&#243;n parcial y 32&#46;4&#37; remisi&#243;n completa de proteinuria&#46; El tratamiento con esteroides&#44; con antihipertensivos y los dep&#243;sitos glomerulares de IgM y C3 se asociaron a mayor supervivencia renal&#46; El tratamiento con esteroides fue el &#250;nico factor que predijo independientemente&#44; mayor supervivencia renal &#40;hazard ratio o HR&#58; 0&#46;07&#44; 0&#46;01-0&#46;9&#41; y remisi&#243;n de proteinuria &#40;HR 0&#46;2&#44; 0&#46;04-0&#46;9&#41;&#46; La hipertensi&#243;n arterial &#40;HR&#58; 6&#46;2&#44; 1&#46;1-35&#46;2&#41;&#44; la insuficiencia renal &#40;HR&#58; 2&#46;9&#44; 1&#46;1-7&#46;6&#41;&#44; la variante celular y la fibrosis intersticial &#40;HR&#58; 5&#46;2&#44; 1&#46;02-26&#46;7&#41; fueron indicadores de pobre remisi&#243;n de proteinuria&#46; Conclusiones&#58; En glomeruloesclerosis focal y segmentaria primaria&#44; el tratamiento con esteroides determin&#243; mayor supervivencia renal y mayor probabilidad de remisi&#243;n de proteinuria&#46; La presencia de insuficiencia renal y fibrosis intersticial determinaron no remisi&#243;n de proteinuria&#46; "
      ]
      "en" => array:1 [
        "resumen" => "Background&#58; In Peru&#44; the incidence of primary focal segmental glomerulosclerosis &#40;PFSGS&#41; has considerably increased in the last decade and at the present&#59; it is the first cause of primary glomerulonephritis in adults&#46; Because of its prevalence and high probability to progress to end-stage renal disease &#40;ESRD&#41;&#44; we searched for factors with prognostic value for renal survival and proteinuria remission&#46; Subjects and methods&#58; Historical cohort of 44 patients&#46; We studied clinical and histological characteristics at the time of renal biopsy and clinical condition and renal function at the end of follow- up&#46; Principal outcomes&#58; renal impairment &"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005415/v0_201502091636/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35441"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originals"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002800000004/v0_201502091636/X2013251408005415/v0_201502091636/en/P-E-S-A391-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005415?idApp=UINPBA000064"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Factors predicting for renal survival in primary focal segmental glomerulosclerosis
FACTORES PRONOSTICOS DE SUPERVIVENCIA RENAL EN GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA PRIMARIA
Jorge Rojas Riveraa, Milagros Péreza, Abdías Hurtadoa, Carmen Asatob
a Servicio de Nefrología Hospital Nacional Arzobispo Loayza y Universidad Peruana Cayetano Heredia, Lima, Lima, Perú,
b Servicio de Patología Quirúrgica, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Perú,
Read
9076
Times
was read the article
3725
Total PDF
5351
Total HTML
Share statistics
 array:21 [
  "pii" => "X2013251408005415"
  "issn" => "20132514"
  "doi" => " "
  "estado" => "S300"
  "fechaPublicacion" => "2008-08-01"
  "documento" => "article"
  "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
  "subdocumento" => "fla"
  "cita" => "Nefrologia &#40;English Version&#41;. 2008;28:439-46"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4395
    "formatos" => array:3 [
      "EPUB" => 279
      "HTML" => 3088
      "PDF" => 1028
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:17 [
      "pii" => "X0211699508005418"
      "issn" => "02116995"
      "doi" => " "
      "estado" => "S300"
      "fechaPublicacion" => "2008-08-01"
      "documento" => "article"
      "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
      "subdocumento" => "fla"
      "cita" => "Nefrologia. 2008;28:439-46"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 25912
        "formatos" => array:3 [
          "EPUB" => 278
          "HTML" => 24321
          "PDF" => 1313
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "titulo" => "FACTORES PRONOSTICOS DE SUPERVIVENCIA RENAL EN GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA PRIMARIA"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "439"
            "paginaFinal" => "446"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Factors predicting for renal survival in primary focal segmental glomerulosclerosis"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jorge Rojas Rivera, Milagros P&#233;rez, Abd&#237;as Hurtado, Carmen Asato"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Jorge"
                "apellidos" => "Rojas Rivera"
              ]
              1 => array:2 [
                "nombre" => "Milagros"
                "apellidos" => "P&#233;rez"
              ]
              2 => array:2 [
                "nombre" => "Abd&#237;as"
                "apellidos" => "Hurtado"
              ]
              3 => array:2 [
                "nombre" => "Carmen"
                "apellidos" => "Asato"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "X2013251408005415"
          "doi" => " "
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005415?idApp=UINPBA000064"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508005418?idApp=UINPBA000064"
      "url" => "/02116995/0000002800000004/v0_201502091416/X0211699508005418/v0_201502091417/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:17 [
    "pii" => "X2013251408005407"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-08-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2008;28:447-52"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 5617
      "formatos" => array:3 [
        "EPUB" => 283
        "HTML" => 4576
        "PDF" => 758
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "Measurement of vascular access blood flow rate during hemodialysis in 38 patients using the thermodilution technique&#46; A comparative study with the Delta-H method"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "447"
          "paginaFinal" => "452"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Exploraci&#243;n funcional del acceso vascular durante la hemodi&#225;lisis en 38 pacientes mediante la t&#233;cnica de termodiluci&#243;n&#46; Estudio comparativo con el m&#233;todo Delta-H&#46;"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ramon Roca-Tey, Rosa Samon, Omar Ibrik, Isabel Gim&#233;nez, Jordi Viladoms"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Ramon"
              "apellidos" => "Roca-Tey"
            ]
            1 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Samon"
            ]
            2 => array:2 [
              "nombre" => "Omar"
              "apellidos" => "Ibrik"
            ]
            3 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Gim&#233;nez"
            ]
            4 => array:2 [
              "nombre" => "Jordi"
              "apellidos" => "Viladoms"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X021169950800540X"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X021169950800540X?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005407?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005407/v0_201502091636/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "X2013251408005423"
    "issn" => "20132514"
    "doi" => " "
    "estado" => "S300"
    "fechaPublicacion" => "2008-08-01"
    "documento" => "article"
    "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/"
    "subdocumento" => "fla"
    "cita" => "Nefrologia &#40;English Version&#41;. 2008;28:433-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 4603
      "formatos" => array:3 [
        "EPUB" => 290
        "HTML" => 3568
        "PDF" => 745
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "titulo" => "On-line sequential hemodiafiltration &#40;OL-S-HDF&#41;&#58; a new therapeutic option"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "433"
          "paginaFinal" => "438"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "HEMODIAFILTRACION EN LINEA SECUENCIAL &#40;HDF-OL-S&#41;&#58; Una nueva opci&#243;n terap&#233;utica&#46;"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Julia Kanter, Marta Puerta Carretero, Rafael Perez Garc&#237;a, Juan Manuel L&#243;pez G&#243;mez, Rosa Jofr&#233;, Patrocinio Rodr&#237;guez Benitez"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Julia"
              "apellidos" => "Kanter"
            ]
            1 => array:2 [
              "nombre" => "Marta"
              "apellidos" => "Puerta Carretero"
            ]
            2 => array:2 [
              "nombre" => "Rafael"
              "apellidos" => "Perez Garc&#237;a"
            ]
            3 => array:2 [
              "nombre" => "Juan Manuel"
              "apellidos" => "L&#243;pez G&#243;mez"
            ]
            4 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Jofr&#233;"
            ]
            5 => array:2 [
              "nombre" => "Patrocinio"
              "apellidos" => "Rodr&#237;guez Benitez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "X0211699508005426"
        "doi" => " "
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508005426?idApp=UINPBA000064"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005423?idApp=UINPBA000064"
    "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005423/v0_201502091636/en/main.assets"
  ]
  "en" => array:12 [
    "idiomaDefecto" => true
    "titulo" => "Factors predicting for renal survival in primary focal segmental glomerulosclerosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "439"
        "paginaFinal" => "446"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Jorge Rojas Rivera, Milagros P&#233;rez, Abd&#237;as Hurtado, Carmen Asato"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Jorge"
            "apellidos" => "Rojas Rivera"
            "email" => array:1 [
              0 => "jerori2003&#64;yahoo&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Milagros"
            "apellidos" => "P&#233;rez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Abd&#237;as"
            "apellidos" => "Hurtado"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "affa"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Carmen"
            "apellidos" => "Asato"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "affb"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Nefrología Hospital Nacional Arzobispo Loayza y Universidad Peruana Cayetano Heredia, Lima, Lima, Perú, "
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "affa"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Patología Quirúrgica, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Perú, "
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "affb"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "FACTORES PRONOSTICOS DE SUPERVIVENCIA RENAL EN GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA PRIMARIA"
      ]
    ]
    "textoCompleto" => "INTRODUCTION <br />Focal segmental glomerulosclerosis &#40;FSGS&#41; is a clinical and pathological syndrome characterized by proteinuria and segmental sclerosis of some glomeruli&#44; with fusion of podocyte processes&#46; Obliteration of glomeruli by cell proliferation or accumulation of extracellular collagen matrix may occur&#46;1 FSGS is classified as primary in the absence of an underlying disease&#46; Clinical signs of FSGS are variable&#44; but most patients have proteinuria in the nephrotic range&#44; arterial hypertension &#40;AHT&#41;&#44; and some grade of kidney function impairment&#46;2 Primary FSGS has a variable prognosis depending on the ethnic&#44; clinical&#44; and histopathological characteristics&#44; treatment scheme&#44; <br />treatment response&#44; and the different observation periods&#46; There is however agreement in that patients with the collapsing and cellular histological variants have a poorer prognosis and experience a relatively rapid kidney function impairment&#46; 3-6 Clinically&#44; it is estimated that 50&#37; of patients with persistent proteinuria in the nephrotic range will progress to end-stage renal disease &#40;ESRD&#41; within 5-10 years&#46; Untreated patients have a poor prognosis&#44; reaching the end stage within 3-6 years&#46;7&#44;8 <br /> <br />An increasing incidence of primary FSGS has been reported in several countries&#46; In the United States&#44; FSGS is the <br />most common cause of nephrotic syndrome and ESRD in black and white adults with primary glomerulonephritis&#46;9-11 A similar trend has been noted in Latin America&#46;12-14 In Peru&#44; FSGS has displaced membranoproliferative glomerulonephritis as the most common primary glomerulonephritis&#46;15&#44;16 However&#44; recent European studies do not show this trend&#46; Thus&#44; in Spain&#44; the glomerulonephritis registry of the SEN17 showed no changes in incidence between 1994 and 2005&#46; Similarly&#44; Cameron18 found no differences in London in the 1970-2000&#44; during which the incidence rate remained at 20&#37;&#46; In Italy&#44;19 incidence changed from 11&#46;7&#37; to 10&#46;4&#37; from 1987 to 1993&#46; Few studies have been conducted in Peru on primary FSGS&#44; and because of its epidemiological significance and its risk of progressing to ESRD&#44; a search was made for clinical and histological factors having a prognostic value in the evolution of kidney function and that would allow for implementing a rational and appropriate therapeutic approach based on current evidence&#46; <br /> <br />PATIENTS AND METHODS <br /> <br />Study design and population <br />A longitudinal&#44; retrospective study was conducted on a historical cohort of patients diagnosed whit primary FSGS based on a kidney biopsy who attended the department of nephrology of Hospital Nacional Arzobispo Loayza from January 1994 to December 2004&#46; Medical records and pathology reports of patients were reviewed&#44; and their demographic&#44; clinical&#44; laboratory&#44; and histological data were recorded at the time of kidney biopsy&#46; Among 64 patients with a histological diagnosis of FSGS&#44; 51 patients had primary FSGS&#46; Clinical follow-up and home visit were performed in 44 patients &#40;86&#46;3&#37;&#41;&#44; while the remaining 7 patients moved and could not be located&#46; These 44 patients formed the final analysis sample&#46; Patients older than 15 years with a diagnosis of primary FSGS&#44; a renal <br />biopsy sample with 8 or more glomeruli&#44; and light microscopy and immunofluorescence studies were enrolled into the study&#46; Patients with concomitant nephropathy&#44; obesity &"
    "pdfFichero" => "P-E-S-A391-EN.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "es" => array:4 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440847"
          "palabras" => array:1 [
            0 => "s&#237;ndrome nefr&#243;tico"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440849"
          "palabras" => array:1 [
            0 => "Glomeruloesclerosis focal y segmentaria"
          ]
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440851"
          "palabras" => array:1 [
            0 => "insuficiencia renal"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec440853"
          "palabras" => array:1 [
            0 => "supervivencia renal"
          ]
        ]
      ]
      "en" => array:4 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440848"
          "palabras" => array:1 [
            0 => "nephrotic syndrome"
          ]
        ]
        1 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440850"
          "palabras" => array:1 [
            0 => "Focal segmental glomerulosclerosis"
          ]
        ]
        2 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440852"
          "palabras" => array:1 [
            0 => "renal failure"
          ]
        ]
        3 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec440854"
          "palabras" => array:1 [
            0 => "renal survival"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "Introducci&#243;n&#58; En Per&#250; la incidencia de glomeruloesclerosis focal y segmentaria primaria ha aumentado considerablemente durante la &#250;ltima d&#233;cada y actualmente es la primera causa de glomerulonefritis primaria en adultos&#46; Por su prevalencia y alta probabilidad de progresar a insuficiencia renal cr&#243;nica terminal&#44; se buscaron factores con valor pron&#243;stico para supervivencia renal y remisi&#243;n de proteinuria&#46; Pacientes y M&#233;todos&#58; Cohorte hist&#243;rica de 44 pacientes&#46; Estudiamos las caracter&#237;sticas cl&#237;nicas e histol&#243;gicas al momento de la biopsia renal y la funci&#243;n renal al seguimiento&#46; Los desenlaces principales fueron&#58; deterioro renal &#40;incremento de creatinina &#62;50&#37; y&#47;o insuficiencia renal terminal&#41; y remisi&#243;n de proteinuria &#40;parcial 0&#46;3-3&#46;49 g&#47;d&#237;a y completa &#60; 0&#46;3g&#47;d&#237;a&#41;&#46; Se usaron curvas de Kaplan-Meier y regresi&#243;n multivariable de Cox&#46; Resultados&#58; El 59&#37; de los pacientes fueron varones&#46; El 54&#46;5&#37; present&#243; insuficiencia renal&#44; 53&#46;5&#37; s&#237;ndrome nefr&#243;tico y 43&#46;2&#37; hipertensi&#243;n arterial al momento de la biopsia&#46; Los tipos histol&#243;gicos fueron&#58; no especificado 75&#37;&#44; celular 13&#46;6&#37;&#44; tip 6&#46;8&#37; e hiliar 4&#46;5&#37;&#46; El 56&#46;8&#37; recibi&#243; esteroides por 6&#46;2 &#177; 4&#46;1 meses y el 32&#37; fue corticodependiente&#46; La funci&#243;n renal empeor&#243; en el 18&#46;2&#37;&#46; El 37&#46;8&#37; logr&#243; remisi&#243;n parcial y 32&#46;4&#37; remisi&#243;n completa de proteinuria&#46; El tratamiento con esteroides&#44; con antihipertensivos y los dep&#243;sitos glomerulares de IgM y C3 se asociaron a mayor supervivencia renal&#46; El tratamiento con esteroides fue el &#250;nico factor que predijo independientemente&#44; mayor supervivencia renal &#40;hazard ratio o HR&#58; 0&#46;07&#44; 0&#46;01-0&#46;9&#41; y remisi&#243;n de proteinuria &#40;HR 0&#46;2&#44; 0&#46;04-0&#46;9&#41;&#46; La hipertensi&#243;n arterial &#40;HR&#58; 6&#46;2&#44; 1&#46;1-35&#46;2&#41;&#44; la insuficiencia renal &#40;HR&#58; 2&#46;9&#44; 1&#46;1-7&#46;6&#41;&#44; la variante celular y la fibrosis intersticial &#40;HR&#58; 5&#46;2&#44; 1&#46;02-26&#46;7&#41; fueron indicadores de pobre remisi&#243;n de proteinuria&#46; Conclusiones&#58; En glomeruloesclerosis focal y segmentaria primaria&#44; el tratamiento con esteroides determin&#243; mayor supervivencia renal y mayor probabilidad de remisi&#243;n de proteinuria&#46; La presencia de insuficiencia renal y fibrosis intersticial determinaron no remisi&#243;n de proteinuria&#46; "
      ]
      "en" => array:1 [
        "resumen" => "Background&#58; In Peru&#44; the incidence of primary focal segmental glomerulosclerosis &#40;PFSGS&#41; has considerably increased in the last decade and at the present&#59; it is the first cause of primary glomerulonephritis in adults&#46; Because of its prevalence and high probability to progress to end-stage renal disease &#40;ESRD&#41;&#44; we searched for factors with prognostic value for renal survival and proteinuria remission&#46; Subjects and methods&#58; Historical cohort of 44 patients&#46; We studied clinical and histological characteristics at the time of renal biopsy and clinical condition and renal function at the end of follow- up&#46; Principal outcomes&#58; renal impairment &"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002800000004/v0_201502091636/X2013251408005415/v0_201502091636/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "35441"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originals"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002800000004/v0_201502091636/X2013251408005415/v0_201502091636/en/P-E-S-A391-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408005415?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
DOI:
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 6 16 22
2024 October 38 80 118
2024 September 50 67 117
2024 August 57 107 164
2024 July 34 85 119
2024 June 54 81 135
2024 May 54 73 127
2024 April 58 60 118
2024 March 45 61 106
2024 February 50 61 111
2024 January 34 65 99
2023 December 26 99 125
2023 November 41 70 111
2023 October 54 64 118
2023 September 63 81 144
2023 August 39 76 115
2023 July 57 73 130
2023 June 64 49 113
2023 May 50 51 101
2023 April 36 38 74
2023 March 31 32 63
2023 February 29 28 57
2023 January 31 37 68
2022 December 45 42 87
2022 November 40 32 72
2022 October 35 38 73
2022 September 43 51 94
2022 August 38 47 85
2022 July 28 49 77
2022 June 33 40 73
2022 May 28 46 74
2022 April 37 51 88
2022 March 28 53 81
2022 February 27 39 66
2022 January 30 39 69
2021 December 35 57 92
2021 November 32 40 72
2021 October 31 54 85
2021 September 32 41 73
2021 August 29 51 80
2021 July 29 46 75
2021 June 31 25 56
2021 May 35 39 74
2021 April 81 38 119
2021 March 69 39 108
2021 February 64 25 89
2021 January 28 16 44
2020 December 17 28 45
2020 November 21 19 40
2020 October 22 18 40
2020 September 16 17 33
2020 August 31 17 48
2020 July 39 23 62
2020 June 41 22 63
2020 May 56 28 84
2020 April 47 37 84
2020 March 49 26 75
2020 February 37 30 67
2020 January 51 48 99
2019 December 36 38 74
2019 November 33 44 77
2019 October 27 29 56
2019 September 31 44 75
2019 August 22 26 48
2019 July 25 33 58
2019 June 30 27 57
2019 May 21 28 49
2019 April 57 33 90
2019 March 71 25 96
2019 February 25 26 51
2019 January 18 21 39
2018 December 60 35 95
2018 November 71 15 86
2018 October 53 14 67
2018 September 57 16 73
2018 August 35 19 54
2018 July 40 24 64
2018 June 33 15 48
2018 May 42 25 67
2018 April 47 12 59
2018 March 31 14 45
2018 February 37 8 45
2018 January 35 10 45
2017 December 45 11 56
2017 November 46 16 62
2017 October 23 15 38
2017 September 34 14 48
2017 August 25 15 40
2017 July 27 18 45
2017 June 26 13 39
2017 May 28 29 57
2017 April 27 26 53
2017 March 18 46 64
2017 February 9 43 52
2017 January 23 21 44
2016 December 44 14 58
2016 November 36 23 59
2016 October 81 28 109
2016 September 77 25 102
2016 August 132 14 146
2016 July 109 8 117
2016 June 99 0 99
2016 May 142 0 142
2016 April 80 0 80
2016 March 77 0 77
2016 February 97 0 97
2016 January 140 0 140
2015 December 105 0 105
2015 November 77 0 77
2015 October 106 0 106
2015 September 77 0 77
2015 August 86 0 86
2015 July 75 0 75
2015 June 33 0 33
2015 May 65 0 65
2015 April 9 0 9
Show all

Follow this link to access the full text of the article

Idiomas
Nefrología (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?