was read the article
array:21 [ "pii" => "X2013251408004425" "issn" => "20132514" "doi" => " " "estado" => "S300" "fechaPublicacion" => "2008-12-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2008;28:653-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2944 "formatos" => array:3 [ "EPUB" => 242 "HTML" => 2284 "PDF" => 418 ] ] "Traduccion" => array:1 [ "es" => array:17 [ "pii" => "X0211699508004428" "issn" => "02116995" "doi" => " " "estado" => "S300" "fechaPublicacion" => "2008-12-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia. 2008;28:653-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 7650 "formatos" => array:3 [ "EPUB" => 306 "HTML" => 6761 "PDF" => 583 ] ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Causa poco frecuente de hipertrigliceridemia en el trasplante renal" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "653" "paginaFinal" => "654" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "An infrequent cause of hypertriglyceridemia in kidney transplantation" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P. Fraile, P. García-Cosmes, T. García, J.M. Tabernero" "autores" => array:4 [ 0 => array:2 [ "Iniciales" => "P." "apellidos" => "Fraile" ] 1 => array:2 [ "Iniciales" => "P." "apellidos" => "García-Cosmes" ] 2 => array:2 [ "Iniciales" => "T." "apellidos" => "García" ] 3 => array:2 [ "Iniciales" => "J.M." "apellidos" => "Tabernero" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "X2013251408004425" "doi" => " " "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408004425?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508004428?idApp=UINPBA000064" "url" => "/02116995/0000002800000006/v0_201502091415/X0211699508004428/v0_201502091415/es/main.assets" ] ] "itemSiguiente" => array:17 [ "pii" => "X2013251408004417" "issn" => "20132514" "doi" => " " "estado" => "S300" "fechaPublicacion" => "2008-12-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2008;28:654-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3839 "formatos" => array:3 [ "EPUB" => 239 "HTML" => 3179 "PDF" => 421 ] ] "en" => array:11 [ "idiomaDefecto" => true "titulo" => "Delayed presentation of femoral pseudoaneurysm after hemodialysis catheter insertion procedure" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "654" "paginaFinal" => "655" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Presentación diferida de un seudoaneurisma femoral tras cateterización venosa para hemodiálisis" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "ANA ESTHER SIRVENT, RICARDO ENRÍQUEZ, ADOLFO REYES, DAVID MARTÍNEZ" "autores" => array:4 [ 0 => array:2 [ "nombre" => "ANA ESTHER" "apellidos" => "SIRVENT" ] 1 => array:2 [ "nombre" => "RICARDO" "apellidos" => "ENRÍQUEZ" ] 2 => array:2 [ "nombre" => "ADOLFO" "apellidos" => "REYES" ] 3 => array:2 [ "nombre" => "DAVID" "apellidos" => "MARTÍNEZ" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "X021169950800441X" "doi" => " " "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X021169950800441X?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408004417?idApp=UINPBA000064" "url" => "/20132514/0000002800000006/v0_201502091634/X2013251408004417/v0_201502091634/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "X2013251408004296" "issn" => "20132514" "doi" => " " "estado" => "S300" "fechaPublicacion" => "2008-12-01" "documento" => "article" "licencia" => "http://www.elsevier.com/open-access/userlicense/1.0/" "subdocumento" => "fla" "cita" => "Nefrologia (English Version). 2008;28:649-51" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3248 "formatos" => array:3 [ "EPUB" => 227 "HTML" => 2612 "PDF" => 409 ] ] "en" => array:11 [ "idiomaDefecto" => true "titulo" => "Recurrent and reversible acute renal failure in a patients with hematuria and Schönlein- Henoch purpura" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "649" "paginaFinal" => "651" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fracaso renal agudo recurrente y reversible en un paciente afecto de hematuria y púrpura de Schönlein-Henoch" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Eduardo Torregrosa de Juan, Julio Hernández Jaras, Juan José Sánchez Canell, Maite Pin, Esther Tamarit, Inmaculada Rico, Consuelo Calvo Gordo, Héctor García Pérez, Ramon Pons Prades, Asuncion Rius, Mª Ángeles Fenollosa" "autores" => array:11 [ 0 => array:2 [ "nombre" => "Eduardo" "apellidos" => "Torregrosa de Juan" ] 1 => array:2 [ "nombre" => "Julio" "apellidos" => "Hernández Jaras" ] 2 => array:2 [ "nombre" => "Juan José" "apellidos" => "Sánchez Canell" ] 3 => array:2 [ "nombre" => "Maite" "apellidos" => "Pin" ] 4 => array:2 [ "nombre" => "Esther" "apellidos" => "Tamarit" ] 5 => array:2 [ "nombre" => "Inmaculada" "apellidos" => "Rico" ] 6 => array:2 [ "nombre" => "Consuelo" "apellidos" => "Calvo Gordo" ] 7 => array:2 [ "nombre" => "Héctor" "apellidos" => "García Pérez" ] 8 => array:2 [ "nombre" => "Ramon" "apellidos" => "Pons Prades" ] 9 => array:2 [ "nombre" => "Asuncion" "apellidos" => "Rius" ] 10 => array:2 [ "nombre" => "Mª Ángeles" "apellidos" => "Fenollosa" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "X0211699508004299" "doi" => " " "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X0211699508004299?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408004296?idApp=UINPBA000064" "url" => "/20132514/0000002800000006/v0_201502091634/X2013251408004296/v0_201502091634/en/main.assets" ] "en" => array:11 [ "idiomaDefecto" => true "titulo" => "An infrequent cause of hypertriglyceridemia in kidney transplantation" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "653" "paginaFinal" => "654" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "P. Fraile, P. García-Cosmes, T. García, J.M. Tabernero" "autores" => array:4 [ 0 => array:4 [ "Iniciales" => "P." "apellidos" => "Fraile" "email" => array:1 [ 0 => "pilarfg@usal.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 1 => array:3 [ "Iniciales" => "P." "apellidos" => "García-Cosmes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 2 => array:3 [ "Iniciales" => "T." "apellidos" => "García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 3 => array:3 [ "Iniciales" => "J.M." "apellidos" => "Tabernero" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Nefrología, Hospital Universitario de Salamanca Salamanca Salamanca España, " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Causa poco frecuente de hipertrigliceridemia en el trasplante renal" ] ] "textoCompleto" => "To the editor: Cardiovascular disease is the most common cause of mortality in long-term transplant recipients; it is <br></br>therefore important to address associated risk factors such as hyperlipidemia. The etiology of hypertriglyceridemia is influenced by obesity, diabetes mellitus, drugs (tacrolimus, β-blockers, corticosteroids, etc., alcohol consumption, <br></br>hypothyroidism, renal failure, nephrotic syndrome and HIV infection.1 Hypertriglyceridemia in the order of 2000 <br></br>mg/dl is almost always of a secondary or familial origin. <br></br><br></br>Heparin is widely used as effective prophylaxis and treatment in patients with thrombosis. Independently of its <br></br>anticoagulant action, the administration of heparin gives rise to two opposite phenomena regarding the effect of the <br></br>drug on the patient lipid profile, derived from its action upon lipoprotein lipase: in the first hour, heparin stimulates the enzyme2 and reduces the triglyceride levels, while posteriorly the enzyme is inhibited and the triglyceride levels consequently increase.3 Although controversial, a number of studies have reported the favorable effects of low molecular weight heparins (LMWHs) upon lipid profile.4,5 <br></br><br></br>We report the case of a 37-year-old male with a history of arterial hypertension, hypercholesterolemia, terminal <br></br>chronic renal failure secondary to reflow nephropathy and a first kidney transplant in 1984, with a return to hemodialysis in 2002 because of chronic graft nephropathy. In 2005, a second dead donor kidney was grafted, with <br></br>the introduction of quadruple immunosuppression in the form of basiliximab, corticosteroids, mycophenolate mofetil <br></br>and tacrolimus. The subsequent course proved favorable, with creatinine clearance 75 ml/min (Cockroft-Gault). Four months after transplantation, the patient developed bilateral deep venous thrombosis and pulmonary thromboembolism. At that time kidney function remained stable, with normal lipid metabolism (cholesterol 213 mg/dl, triglycerides 163 mg/dl) and thyroid hormones, and normal thrombophilia findings. Treatment was provided in the form of tacrolimus, mycophenolate mofetil, prednisone, bisoprolol, furosemide and omeprazole.  Anticoagulation was started with dalteparin 18,000 U/24 hours. The posterior controls showed a gradual increase in triglyceride levels (fig. 1); gemfibrozil was therefore started at increasing doses, associated to atorvastatin ¿ though with scant response. Due to the suspicion of hypertriglyceridemia secondary to dalteparin treatment, the latter was replaced with acenocoumarol. This was followed by a decrease in triglyceride levels, as a result of which the lipidlowering medication was gradually withdrawn (fig. 1). <br></br><br></br>Hypertriglyceridemia is a side effect of heparin administration. Our patient was obese, with grade II renal failure, <br></br>and was subjected to antihypertensive treatment (bisoprolol) and immunosuppression (corticosteroids and tacrolimus). All these hypertriglyceridemiacontributing factors were present before the start of treatment with dalteparin. From introduction of the latter drug, the triglyceride levels were found to be uncontrollable despite intensive medical care. Only dalteparin withdrawal proved effective. <br></br><br></br>We therefore conclude that dalteparin, one of the LMWHs with the most beneficial effects upon patient lipid profile,6 was the cause of severe hypertriglyceridemia in our case. This is an unusual side effect of LMWHs that nevertheless <br></br>must be taken into consideration by physicians, in view of the widespread use of both LMWHs and unfractionated <br></br>heparins. In addition, their use in patients at high cardiovascular risk must be carefully evaluated. <br></br>" "pdfFichero" => "P-E-S-A338-EN.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "Sr Director: La enfermedad cardiovascular es la causa más frecuente de muerte en enfermos trasplantados a largo plazo, por lo que es importante incidir en factores de riesgo como la hiperlipemia. En la etiología de la hipertrigliceridemia influyen la obesidad, diabetes mellitus, medicamentos (tacrolimus, β-bloqueantes, corticoesteroides,...), consumo de alcohol, hipotiroidismo, insuficiencia renal, síndrome nefrótico e infección por VIH1. Hipertrigliceridemias entorno a 2000 mg/dL casi siempre son secundarias o de origen familiar. " ] "en" => array:1 [ "resumen" => "To the editor: Cardiovascular disease is the most common cause of mortality in long-term transplant recipients; it is therefore important to address associated risk factors such as hyperlipidemia. The etiology of hypertriglyceridemia is influenced by obesity, diabetes mellitus, drugs (tacrolimus, β-blockers, corticosteroids, etc., alcohol consumption, hypothyroidism, renal failure, nephrotic syndrome and HIV infection.1 Hypertriglyceridemia in the order of 2000 mg/dl is almost always of a secondary or familial origin." ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002800000006/v0_201502091634/X2013251408004425/v0_201502091634/en/main.assets" "Apartado" => array:4 [ "identificador" => "35436" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002800000006/v0_201502091634/X2013251408004425/v0_201502091634/en/P-E-S-A338-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251408004425?idApp=UINPBA000064" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 7 | 9 | 16 |
2024 October | 42 | 26 | 68 |
2024 September | 55 | 27 | 82 |
2024 August | 47 | 45 | 92 |
2024 July | 38 | 23 | 61 |
2024 June | 70 | 31 | 101 |
2024 May | 56 | 35 | 91 |
2024 April | 46 | 23 | 69 |
2024 March | 44 | 24 | 68 |
2024 February | 33 | 30 | 63 |
2024 January | 30 | 22 | 52 |
2023 December | 25 | 25 | 50 |
2023 November | 35 | 41 | 76 |
2023 October | 39 | 43 | 82 |
2023 September | 48 | 27 | 75 |
2023 August | 33 | 33 | 66 |
2023 July | 32 | 26 | 58 |
2023 June | 45 | 15 | 60 |
2023 May | 51 | 27 | 78 |
2023 April | 28 | 16 | 44 |
2023 March | 37 | 16 | 53 |
2023 February | 30 | 23 | 53 |
2023 January | 30 | 22 | 52 |
2022 December | 31 | 25 | 56 |
2022 November | 43 | 23 | 66 |
2022 October | 34 | 34 | 68 |
2022 September | 53 | 33 | 86 |
2022 August | 56 | 42 | 98 |
2022 July | 33 | 40 | 73 |
2022 June | 62 | 29 | 91 |
2022 May | 49 | 34 | 83 |
2022 April | 29 | 37 | 66 |
2022 March | 48 | 43 | 91 |
2022 February | 39 | 33 | 72 |
2022 January | 26 | 27 | 53 |
2021 December | 40 | 37 | 77 |
2021 November | 65 | 37 | 102 |
2021 October | 59 | 34 | 93 |
2021 September | 38 | 32 | 70 |
2021 August | 49 | 40 | 89 |
2021 July | 65 | 32 | 97 |
2021 June | 44 | 14 | 58 |
2021 May | 32 | 31 | 63 |
2021 April | 61 | 35 | 96 |
2021 March | 47 | 21 | 68 |
2021 February | 62 | 21 | 83 |
2021 January | 50 | 17 | 67 |
2020 December | 32 | 15 | 47 |
2020 November | 49 | 27 | 76 |
2020 October | 27 | 15 | 42 |
2020 September | 24 | 9 | 33 |
2020 August | 43 | 9 | 52 |
2020 July | 35 | 8 | 43 |
2020 June | 39 | 12 | 51 |
2020 May | 49 | 13 | 62 |
2020 April | 32 | 9 | 41 |
2020 March | 35 | 10 | 45 |
2020 February | 33 | 13 | 46 |
2020 January | 40 | 22 | 62 |
2019 December | 55 | 15 | 70 |
2019 November | 42 | 9 | 51 |
2019 October | 58 | 13 | 71 |
2019 September | 50 | 13 | 63 |
2019 August | 32 | 8 | 40 |
2019 July | 33 | 19 | 52 |
2019 June | 24 | 9 | 33 |
2019 May | 33 | 9 | 42 |
2019 April | 35 | 31 | 66 |
2019 March | 13 | 8 | 21 |
2019 February | 12 | 14 | 26 |
2019 January | 22 | 20 | 42 |
2018 December | 35 | 30 | 65 |
2018 November | 52 | 10 | 62 |
2018 October | 51 | 9 | 60 |
2018 September | 43 | 6 | 49 |
2018 August | 31 | 16 | 47 |
2018 July | 22 | 13 | 35 |
2018 June | 23 | 11 | 34 |
2018 May | 22 | 9 | 31 |
2018 April | 25 | 5 | 30 |
2018 March | 21 | 7 | 28 |
2018 February | 25 | 2 | 27 |
2018 January | 21 | 5 | 26 |
2017 December | 33 | 7 | 40 |
2017 November | 29 | 1 | 30 |
2017 October | 28 | 11 | 39 |
2017 September | 21 | 7 | 28 |
2017 August | 26 | 8 | 34 |
2017 July | 28 | 8 | 36 |
2017 June | 22 | 5 | 27 |
2017 May | 28 | 10 | 38 |
2017 April | 21 | 6 | 27 |
2017 March | 14 | 4 | 18 |
2017 February | 9 | 5 | 14 |
2017 January | 13 | 1 | 14 |
2016 December | 32 | 1 | 33 |
2016 November | 27 | 6 | 33 |
2016 October | 54 | 8 | 62 |
2016 September | 61 | 4 | 65 |
2016 August | 95 | 3 | 98 |
2016 July | 82 | 3 | 85 |
2016 June | 85 | 0 | 85 |
2016 May | 91 | 0 | 91 |
2016 April | 52 | 0 | 52 |
2016 March | 46 | 0 | 46 |
2016 February | 55 | 0 | 55 |
2016 January | 69 | 0 | 69 |
2015 December | 99 | 0 | 99 |
2015 November | 56 | 0 | 56 |
2015 October | 49 | 0 | 49 |
2015 September | 38 | 0 | 38 |
2015 August | 62 | 0 | 62 |
2015 July | 30 | 0 | 30 |
2015 June | 28 | 0 | 28 |
2015 May | 55 | 0 | 55 |
2015 April | 5 | 0 | 5 |