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      "titulo" => "ADVERSE REACTIONS TO POLISULPHONE MEMBRANE DIALYZERS DURIND HEMODIALYSIS ABSTRACT"
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        "titulo" => "Fiebre de origen desconocido y fracaso renal agudo"
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        "resumen" => "Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin. The most prevalent causes are infections, malignancies and collagen-vascular diseases. Drug fever are responsable about 3-5 % of these cases. Acute interstitial nephritis is most often induced by drug therapy, especially antibiotics, non steroidal antiinflammatory drugs and others. The clinical presentation, laboratory manifestations, etiology and treatment of both process are well recognized. We report a case of patient with unknown origin fever caused by acute interstitial nephritis with origin in nonsteroidal antiinflammatory therapy. The difficult of diagnosis (based in renal biopsy and corticosteroids treatment), clinical and laboratory findings, evolution and especially the rarely of this case are considered in this paper. "
      ]
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        "resumen" => "Los clínicos nos referimos a la fiebre de origen desconocido como aquella, prolongada en el tiempo, y de etiología incierta tras estudios hospitalarios adecuados. Las causas mas frecuentes son infecciones, tumores y vasculitis-colagenosis. Los fármacos son responsables del 3-5 % de estos casos. La nefritis intersticial aguda es con mucha frecuencia provocada por fármacos, especialmente antibióticos, antiinflamatorios no esteroideos y otros. Las formas de presentación clínica, hallazgos de laboratorio, etiología y tratamiento de estos procesos son bien conocidos. Presentamos el caso de una paciente con fiebre de origen desconocido provocado por una nefritis intersticial aguda con origen en la utilización de antiinflamatorios no esteroideos. La dificultad en el diagnóstico (realizado tras practicar biopsia renal e inicio de corticoterapia), las manifestaciones clínicas y hallazgos de laboratorio, la evolución y especialmente la rareza del cuadro son comentadas en el presente artículo. "
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