Preliminary study on efficacy and tolerance of a «coupage» of olive oil in patients with chronic kidney disease. Nutritonal evalution
Estudio preliminar sobre eficacia y tolerancia de un «coupage» de aceite de oliva en pacientes con enfermedad renal crónica. Evaluación del estado de nutrición
Vicente Pérez-Bañasco, Jose Manuel Gil-Cunquero, Francisco José Borrego-Utiel, Manuela Gassó, Pilar Segura-Torres, Fernando Warletta, J.L.
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Nutritonal evalution" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "472" "paginaFinal" => "481" ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Vicente Pérez-Bañasco, Jose Manuel Gil-Cunquero, Francisco José Borrego-Utiel, Manuela Gassó, Pilar Segura-Torres, Fernando Warletta, J.L." "autores" => array:1 [ 0 => array:1 [ "nombre" => "Vicente Pérez-Bañasco, Jose Manuel Gil-Cunquero, Francisco José Borrego-Utiel, Manuela Gassó, Pilar Segura-Torres, Fernando Warletta, J.L." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estudio preliminar sobre eficacia y tolerancia de un «coupage» de aceite de oliva en pacientes con enfermedad renal crónica. Evaluación del estado de nutrición" ] ] "pdfFichero" => "P-E-S-A4674-EN.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec436254" "palabras" => array:1 [ 0 => "aceite de oliva, ¿ coupage oHo¿, enfermedad renal crónica, malnutrición, inflamación, HOMA" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec436255" "palabras" => array:1 [ 0 => "olive oil, ¿oHo¿, chronic kidney disease, malnutrition, inflammation, HOMA" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "The discrepancies among data reported by using olive oil (OO) in humans appear to be due to the great differences between the different OO used. Based on structure/function relationships we have chemically optimized an OO through the rational mixture ("coupage") of several Spanish extra virgin olive oils (methodology "oHo"). Patients with chronic kidney disease (CKD) develop a progressive picture of malnutrition and inflammation that lead them to an elevated risk of cardiovascular disease. In a pilot, randomised trial the nutritional efficacy and safety of ¿oHo¿ were evaluated in 32 patients (mean age 60,8 ± 13,2 years old; 16 women) with CKD (KDIGO stages 4-5) at predialysis. After a 7 days wash out for statins and ACE inhibitors 19 patients had ¿oHo¿ at doses of 60 mL/day (20 mL t.i.d) for 30 consecutive days, whilst 13 patients remain as a control group without ¿oHo¿. At the end of the study only patients having ¿oHo¿ showed significant increases of serum albumin (p <0 05 and not significant increases of total proteins weight bmi cholesterol p <0 05 and hdl-cholesterol p <0 01 increased with oho the number of cases pathologic homa-ir in control group from 1 to 2 patients whilst decreased none no significant changes minerals arterial pressure hemoglobin and other parameters related ckd were seen after a 30 days follow-up all came back basal ones excepting for blood that significantly p <0 05 tolerance was excellent and constipation significantly diminished p <0 001 in the oho group of importance none these biological changes were seen regular consumers other conventional olive oils control intriguing results by first time appear to partially satisfy recent claims reverse epidemiology about need a more correct nutrition ckd patients however data be proved larger trials as well under dialysis with harder inflammatory malnutrition conditions</0> </0> </0> </0> </0>" ] "es" => array:1 [ "resumen" => "Las discrepancias en las acciones del aceite de oliva (AO) en humanos, parecen deberse a las diferencias existentes entre los distintos aceites utilizados en los estudios publicados, fundamentalmente en sujetos sanos. Basados en relaciones estructura/función, se ha optimizado químicamente un AO mediante la mezcla racional (¿coupage¿) de diversos aceites de oliva virgen extra españoles (metodología ¿oHo¿â). Los pacientes con enfermedad renal crónica (ERC) desarrollan un cuadro progresivo de malnutrición e inflamación sobre el que asienta su elevado riesgo de enfermedad cardiovascular. En un estudio piloto, controlado y aleatorizado se ha evaluado la eficacia y seguridad de ¿oHo¿ en 32 pacientes (16 mujeres) con ERC (estadios 4-5) en prediálisis, (edad media 60,8 ± 13,2 años). Tras un período de lavado de 7 días para inhibidores de la ECA y estatinas, 19 pacientes tomaron ¿oHo¿ (60 ml/día, en 3 tomas) durante 30 días consecutivos y 13 permanecieron como grupo control. Al final del estudio, solamente los pacientes con ¿oHo¿ mostraron incrementos significativos en los niveles de albúmina sérica (p <0 05 así como tendencia al aumento del peso y de las proteínas totales cifras colesterol total p <0 05 y hdl p <0 01 aumentaron en el grupo oho número de casos con homa patológico subió 1 a 2 pacientes control mientras que los iniciales normalizaron sus índices no se observaron cambios parámetros relacionados específicamente la erc: minerales creatinina anemia etc tras un período seguimiento 30 días todos cambiaron tratamiento regresaron cifras basales excepto presión arterial media disminuyó p <0 05 la tolerancia fue excelente y el estreñimiento disminuyó significativamente <0 001 en el grupo oho dada la originalidad del estudio estos resultados deberán ser comprobados con estudios más amplios</0> </0> </0> </0> </0>" ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002700000004/v0_201502091551/X201325140702156X/v0_201502091551/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002700000004/v0_201502091551/X201325140702156X/v0_201502091551/en/P-E-S-A4674-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X201325140702156X?idApp=UINPBA000064" ]
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