The Cockcroft-Gault equation is better than MDRD equation to estimate the glomerular filtration rate in patients with advanced chronic renal failure.
La ecuación de Cockcroft-Gault es preferible a la ecuación MDRD para medir el filtrado glomerular en la insuficiencia renal crónica avanzada.
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filtration rate in patients with advanced chronic renal failure." 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Madrid., " "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La ecuación de Cockcroft-Gault es preferible a la ecuación MDRD para medir el filtrado glomerular en la insuficiencia renal crónica avanzada." ] ] "pdfFichero" => "P-E-S-A4461-EN.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec436305" "palabras" => array:4 [ 0 => "Filtrado glomerular" 1 => "Ecuación Cockcroft-Gault" 2 => "Ecuación MDRD" 3 => "Insuficiencia renal crónica" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec436306" "palabras" => array:4 [ 0 => "Glomerular filtration rate" 1 => "Cockcroft-Gault equation" 2 => "MDRD equation" 3 => "Chronic renal failure" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "ABSTRACT The aim of this study was to compare the accuracy of three kidney function estimating equations: classic Cockcroft-Gault (classic CG), corrected Cockcroft-Gault (corrected CG) and simplified Modification of Diet in Renal Disease (MDRD), in patients with advanced chronic renal failure. The study was made in 84 nondialyzed patients with chronic renal disease in stage 4 or 5. The glomerular filtration rate was measured on a 24-hour urine collection as the arithmetic mean of the urea and creatinine clearances (CUrCr). In each patient, the difference between each estimating equation and the measured glomerular filtration rate was calculated. The absolute difference expressed as a percentage of the measured glomerular filtration rate indicates the intermethod variability. In the total group the glomerular filtration rate measured as the CUrCr was de 13,5±5,1 ml/min/1.73m²; and the results of the estimating equations were: classic CG 14,2±5 (p <0 05 corrected cg 12 4 2 p <0 01 and mdrd : 12 1 4 8 ml min 73m p <0 01 the variability of estimating equations was 15 2 12 17 1 13 4 and 19 3 p <0 05 for classic cg corrected and mdrd respectively the percent of estimates falling within 30 above o below measured glomerular filtration rate was 90 87 79 intraclass correlation coefficients respect to curcr were 0 86 81 77 variability but not or showed a positive with r="0,25," p <0 05 in patients with chronic renal disease stage 5 the variability of different estimating equations was similar we conclude that our population advanced failure classic cg equation is more accurate than mdrd corrected has not any advantage respect to</0> </0> </0> </0> </0>" ] "es" => array:1 [ "resumen" => "RESUMEN El objetivo del presente trabajo es el estudio del grado de concordancia entre el filtrado glomerular medido como la media aritmética de los aclaramientos de urea y creatinina (AclUrCr), y las ecuaciones de Cockcroft-Gault clásica (CG clásica), Cockcroft-Gault corregida (CG corregida) y MDRD abreviada, en una población de enfermos con enfermedad renal crónica en estadio 4 y 5. El estudio ha sido realizado en 84 enfermos atendidos en la consulta de prediálisis. La variabilidad intermétodo ha sido estudiada mediante la diferencia relativa (100 x diferencia absoluta/media de los métodos analizados). En el grupo total, el filtrado glomerular considerado como la media de los aclaramientos de urea y creatinina fue de 13,5±5,1 ml/min/1.73m²; y el resultado de las diferentes ecuaciones fue: CG clásica 14,2±5 (p <0 05 cg corregida 12 4 2 p <0 01 y mdrd 12 1 4 8 ml min 73m p <0 01 la variabilidad intermétodo de las diferentes ecuaciones con respecto al aclurcr fue 15 2 12 17 1 13 4 y 19 3 p <0 05 para cg clásica corregida y mdrd respectivamente el porcentaje de mediciones que caen dentro del 30 por encima o debajo valor conseguido con método referencia fue 90 las realizadas la ecuación 87 79 abreviada coeficiente correlación intraclase entre media los aclaramientos urea creatinina distintas ecuaciones 0 86 81 77 variabilidad pero no otras dos mostró un positiva filtrado glomerular a mayor r="0,25," p <0 05 en los enfermos con insuficiencia renal crónica estadio 5 n="59)," la variabilidad intermétodo fue similar las tres ecuaciones analizadas podemos concluir que nuestra población avanzada ecuación cg clásica tiene mejor equivalencia el filtrado glomerular medido como media de aclaramientos urea y creatinina mdrd abreviada corregida no mejora grado concordancia por tanto aporta ninguna ventaja sobre</0> </0> </0> </0> </0>" ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000002700000003/v0_201502091552/X2013251407021371/v0_201502091552/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/20132514/0000002700000003/v0_201502091552/X2013251407021371/v0_201502091552/en/P-E-S-A4461-EN.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251407021371?idApp=UINPBA000064" ]
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