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Baclofen-associated encephalopathy in a hemodialysis patient with hiccups
Encefalopatía asociada a baclofeno como tratamiento del hipo refractario en un paciente en hemodiáli
L.F. Quintana , A. Lladó , M. Butjosa, J. Santamaría, E. Poch
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          "identificador" => "xpalclavsec436499"
          "palabras" => array:1 [
            0 => "Baclofeno, hipo, encefalopatía, hemodiálisis"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "El baclofeno es un agonista del ácido gamma-amino-butírico (GABA) que se utiliza como relajante muscular de acción central en patologías caracterizadas por espasticidad o en el hipo refractario a otros tratamientos. Aunque el uso del baclofeno en pacientes en hemodiálisis con hipo intratable se ha descrito como seguro y exitoso a dosis de 5 mg/día, su farmacodinámica y farmacocinética en la insuficiencia renal avanzada es poco conocida. Presentamos el caso de un paciente en hemodiálisis que desarrolló un cuadro de encefalopatía asociado a baclofeno con esta dosis recomendada de la medicación."
      ]
      "en" => array:1 [
        "resumen" => "Baclofen is a centrally acting gamma-ammino butyric acid agonist that is used like muscular relaxant in disorders with spasticity and intractable hiccups. Although encouraging and safe results were provided 5 mg/day in hemodialysis patients, his pharmacokinetic and pharmacodinamic properties are not well known in end stage renal disease. We present here the case of a hemodialysis patient with intractable hiccups who developed baclofen-associated encephalopathy with this recommended dose."
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/20132514/0000002600000004/v0_201502091552/X2013251406020187/v0_201502091552/en/main.assets"
  "Apartado" => null
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/X2013251406020187?idApp=UINPBA000064"
]
Article information
ISSN: 20132514
Original language: English
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