Letter to the Editor
A renal failure related to the feline world
Un fracaso renal relacionado con el mundo felino
Read
1055
Timeswas read the article
453
Total PDF
602
Total HTML
Share statistics
array:23 [ "pii" => "S2013251424000798" "issn" => "20132514" "doi" => "10.1016/j.nefroe.2024.03.020" "estado" => "S300" "fechaPublicacion" => "2024-03-01" "aid" => "1162" "copyrightAnyo" => "2024" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Nefrologia (English Version). 2024;44:308-10" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0211699523000644" "issn" => "02116995" "doi" => "10.1016/j.nefro.2023.04.003" "estado" => "S300" "fechaPublicacion" => "2024-03-01" "aid" => "1162" "copyright" => "Sociedad Española de Nefrología" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Nefrologia. 2024;44:308-10" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">CARTA AL DIRECTOR</span>" "titulo" => "Un fracaso renal relacionado con el mundo felino" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "308" "paginaFinal" => "310" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "A renal failure related to the feline world" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig1" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 639 "Ancho" => 2533 "Tamanyo" => 354438 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Muestra de hematoxilina-eosina y <span class="elsevierStyleItalic">Periodic Acid-Schiff</span> (PAS) positivo de un cilindro renal vista al microscopio óptico. En la imagen de la izquierda se observan dos glomérulos renales, pudiendo objetivar un gran crecimiento extracelular con numerosos núcleos en su interior (semiluna celular) (flechas rojas), reduciendo el penacho renal (flecha verde). En la imagen central se ve un glomérulo con una semiluna celular. La imagen de la izquierda muestra la inmunofluorescencia IgM positiva<span class="elsevierStyleItalic">.</span></p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Adriana María Cavada Bustamante, Clara Sanz García, Natalia Menéndez García, María Gago Fraile, Blanca Vivanco Allende, José Joaquín Bande Fernández" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Adriana María" "apellidos" => "Cavada Bustamante" ] 1 => array:2 [ "nombre" => "Clara" "apellidos" => "Sanz García" ] 2 => array:2 [ "nombre" => "Natalia" "apellidos" => "Menéndez García" ] 3 => array:2 [ "nombre" => "María" "apellidos" => "Gago Fraile" ] 4 => array:2 [ "nombre" => "Blanca" "apellidos" => "Vivanco Allende" ] 5 => array:2 [ "nombre" => "José Joaquín" "apellidos" => "Bande Fernández" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2013251424000798" "doi" => "10.1016/j.nefroe.2024.03.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251424000798?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699523000644?idApp=UINPBA000064" "url" => "/02116995/0000004400000002/v1_202403050505/S0211699523000644/v1_202403050505/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S2013251424000804" "issn" => "20132514" "doi" => "10.1016/j.nefroe.2024.03.021" "estado" => "S300" "fechaPublicacion" => "2024-03-01" "aid" => "1167" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Nefrologia (English Version). 2024;44:310-1" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "“Latent tuberculosis vs active tuberculosis in dialysis patients: lessons from an epidemiological study in orense”" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "310" "paginaFinal" => "311" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "“Tuberculosis latente vs tuberculosis activa en pacientes en diálisis: enseñanzas de un estudio epidemiológico en orense”" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Maria Hernansanz Perez, Maria Jesús Camba Caride, Cristina Pérez Melón, Beatriz Millán Diaz" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Maria Hernansanz" "apellidos" => "Perez" ] 1 => array:2 [ "nombre" => "Maria Jesús Camba" "apellidos" => "Caride" ] 2 => array:2 [ "nombre" => "Cristina Pérez" "apellidos" => "Melón" ] 3 => array:2 [ "nombre" => "Beatriz Millán" "apellidos" => "Diaz" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0211699523000693" "doi" => "10.1016/j.nefro.2023.04.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699523000693?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251424000804?idApp=UINPBA000064" "url" => "/20132514/0000004400000002/v2_202410292119/S2013251424000804/v2_202410292119/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2013251424000622" "issn" => "20132514" "doi" => "10.1016/j.nefroe.2024.03.004" "estado" => "S300" "fechaPublicacion" => "2024-03-01" "aid" => "1154" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Nefrologia (English Version). 2024;44:306-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Obinutuzumab in the treatment of PLA2R-positive membranous glomerulonephritis resistant to treatment" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "306" "paginaFinal" => "307" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Obinutuzumab en el tratamiento de glomerulonefritis membranosa PLA2R positiva resistente a tratamiento" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1490 "Ancho" => 2508 "Tamanyo" => 234401 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0140" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Evolution of the estimated glomerular filtration rate (dashed line) and the protein/creatinine ratio (solid line).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Francisco José de la Prada Álvarez, Melissa Cintra Cabrera, Marina Almenara Tejederas, Javier Burgos Martin, Fabiola Alonso García, Mercedes Salgueira Lazo" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Francisco José" "apellidos" => "de la Prada Álvarez" ] 1 => array:2 [ "nombre" => "Melissa" "apellidos" => "Cintra Cabrera" ] 2 => array:2 [ "nombre" => "Marina" "apellidos" => "Almenara Tejederas" ] 3 => array:2 [ "nombre" => "Javier" "apellidos" => "Burgos Martin" ] 4 => array:2 [ "nombre" => "Fabiola" "apellidos" => "Alonso García" ] 5 => array:2 [ "nombre" => "Mercedes" "apellidos" => "Salgueira Lazo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0211699523000413" "doi" => "10.1016/j.nefro.2023.03.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0211699523000413?idApp=UINPBA000064" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251424000622?idApp=UINPBA000064" "url" => "/20132514/0000004400000002/v2_202410292119/S2013251424000622/v2_202410292119/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "A renal failure related to the feline world" "tieneTextoCompleto" => true "saludo" => "Dear Editor," "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "308" "paginaFinal" => "310" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Adriana M. Cavada-Bustamante, Clara Sanz García, Natalia Menéndez García, María Gago Fraile, Blanca Vivanco Allende, Joaquín Bande Fernández" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Adriana M." "apellidos" => "Cavada-Bustamante" "email" => array:1 [ 0 => "adriana.cavada.bustamante@navarra.es" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Clara" "apellidos" => "Sanz García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Natalia" "apellidos" => "Menéndez García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "María" "apellidos" => "Gago Fraile" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "Blanca" "apellidos" => "Vivanco Allende" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "Joaquín" "apellidos" => "Bande Fernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Nefrología, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Anatomía Patología, HUCA, Oviedo, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Nefrología, Hospital Universitario de Navarra, Pamplona" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Un fracaso renal relacionado con el mundo felino" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 639 "Ancho" => 2533 "Tamanyo" => 346424 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Haematoxylin-eosin and Periodic Acid-Schiff (PAS) positive sample from a renal cast seen under an optical microscope. In the image on the left, two renal glomeruli can be seen, showing a large extracellular growth containing numerous nuclei (cellular crescent) (red arrows), reducing the renal tuft (green arrow). The central image shows a glomerulus with a cellular crescent. The image on the left shows positive IgM immunofluorescence.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Acute kidney injury (AKI) is one of the most common reasons for consultation.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Although the most common aetiology is pre-renal, there are geographical, cultural and economic factors that can vary the most probable cause and the form of clinical presentation (the spectrum of which can also be very broad).<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The hospital incidence is variable, reaching close to 20%.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> AKI leads to an increased risk of death and a variable percentage of these patients do not recover their baseline renal function.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">We present the case of an 80-year-old woman, independent in activities of daily living (IADL) and living in a rural area. She was diagnosed with high blood pressure, anticoagulated paroxysmal atrial fibrillation, chronic kidney disease stage 3a A1 of unknown ethiology without nephrology follow-up (baseline creatinine of 1.08 mg/dl, urea 68 mg/dl and glomerular filtration rate [GFR] 49 ml/min/1.76 m<span class="elsevierStyleSup">2</span>) and aortic stenosis operated on with a bioprosthetic valve three years earlier. Her long-term treatment included bisoprolol, lorazepam, furosemide, olmesartan/hydrochlorothiazide, statin and Adiro (acetylsalicylic acid).</p><p id="par0015" class="elsevierStylePara elsevierViewall">She went to the Emergency Room with a four-month history of a constitutional syndrome with asthenia, weight loss of 10 kg and hyporexia. Her vital signs were normal. Additional tests revealed microcytic anaemia with haemoglobin of 8.7 and mild lymphopenia. Deteriorated renal function was observed, with a creatinine level of 2.37 mg/dl, urea 85 mg/dl and with active sediment and negative urine culture. The patient was admitted, requesting: computed tomography (CT) of chest/abdomen; endoscopic studies of gastrointestinal system; and complete blood count with proteins.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Gastroscopy, colonoscopy and CT did not yield significant findings, reasonably ruling out cancer as the cause of her constitutional syndrome. In the analysis of proteins, a biclonal IgG-kappa lambda peak was found with negative immunofixation in urine, so a bone marrow biopsy was performed, with no abnormal findings. In parallel, the patient's renal function was progressively deteriorating, with a peak creatinine level of 8.64. mg/dl (previous 5.99 - >6.2 - >7.46 mg/dl) and with persistence of non-nephrotic proteinuria (protein/creatinine ratio 2,032 mg/g) and microhaematuria, with a progressive tendency to hypertension and oliguria leading to heart failure. This was in the context of complete nephritic syndrome with the need for urgent haemodialysis and, at that point, further immunological studies were requested.</p><p id="par0025" class="elsevierStylePara elsevierViewall">During this whole process, an autoimmunity study was requested with antinuclear antibodies (ANA), antineutrophil cytoplasmic antibodies (ANCA) and anti-glomerular basement membrane antibodies (anti-GBM). They were negative, showing a decrease in C3 0.73 g/l (0.90–1.80) with an increase in rheumatoid factor 67.5 U/l (0–14). In light of the above and with no improvement in kidney function in the context of established nephritic syndrome without a clear cause, a kidney biopsy was performed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The biopsy report referred to a mesangiocapillary glomerulonephritis (GN) with extracapillary proliferation (cellular crescents), with very positive IgM immunofluorescence with negative C3.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">Given these findings, an infectious process with an atypical presentation was suspected as the cause of the condition, and taking into account the rural area of residence of the patient, the diagnostic series was expanded with zoonosis serologies (<span class="elsevierStyleItalic">Coxiella</span>, <span class="elsevierStyleItalic">Bartonella henselae</span> (BH), <span class="elsevierStyleItalic">Leptospira</span> and <span class="elsevierStyleItalic">Borrelia</span>). In the end, positive serology for BH was obtained (IgM and IgG titre 1/256). A blood polymerase chain reaction (PCR) was requested for <span class="elsevierStyleItalic">Bartonella</span> twice, which was negative in both cases. The possibility of endocarditis was raised without a conclusive diagnosis after transoesophageal echocardiogram and positron emission tomography (PET), but it was finally decided to treat the condition as such, with a regimen of doxycycline 100 mg and rifampicin 300 mg every 12 h for at least two weeks.</p><p id="par0035" class="elsevierStylePara elsevierViewall">After starting antibiotic therapy, the patient's clinical condition and blood test results progressed favourably, with improvement in kidney function, and the haemodialysis sessions could be discontinued. Additionally, her levels of rheumatoid factor and C3 returned to normal (<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>). Given the persistence of positive IgM for BH, doxycycline was continued for six weeks. Three months later, the IgM was negative and the IgG was positive, with a titre 1/512 for BH with creatinine of 2.52 mg/dl and urea 111 mg/dl.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0040" class="elsevierStylePara elsevierViewall">This article has described a nephritic syndrome caused by a mesangiocapillary GN with cellular crescents secondary to an active BH infection, with no similar cases found in the literature.</p><p id="par0045" class="elsevierStylePara elsevierViewall">The clinical spectrum of BH infection is broad, ranging from a latent and non-specific condition affecting the general state to cat-scratch disease and endocarditis with negative blood cultures.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a> It can even trigger immunological phenomena, such as mesangiocapillary glomerulonephritis, which over several months can lead to extracapillary proliferation. Immunological manifestations are usually related to the manifestation of the infection.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6–9</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The exceptional aspect of our case is that mesangiocapillary glomerulonephritis was the only certain clinical manifestation of BH infection. With this case we wanted to stress the importance of the medical history, including patients' personal information, such as place of residence, as all of this needs to be taken into account for the differential diagnosis and approach to acute kidney injury.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0055" class="elsevierStylePara elsevierViewall">No funding was received for this study.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 639 "Ancho" => 2533 "Tamanyo" => 346424 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Haematoxylin-eosin and Periodic Acid-Schiff (PAS) positive sample from a renal cast seen under an optical microscope. In the image on the left, two renal glomeruli can be seen, showing a large extracellular growth containing numerous nuclei (cellular crescent) (red arrows), reducing the renal tuft (green arrow). The central image shows a glomerulus with a cellular crescent. The image on the left shows positive IgM immunofluorescence.</p>" ] ] 1 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0020" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">17 Aug \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">19 Aug \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">18 Sep \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">10 Nov \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">25 Nov \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">C3 g/l \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.91 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.73 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.45 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.93 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.83 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">C4 g/l \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.11 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.2 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Rheumatoid factor kU/l \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">67.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">91 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">55.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">11.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">9.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Diuresis ml \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2,000 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2,300 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">800 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1,500 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1,500 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Creatinine mg/dl \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4.83 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5.27 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2.52 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3704411.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Progression of immunological parameters and renal function.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Summary of clinical practice guidelines for acute kidney injury" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.P. Walther" 1 => "A.S. Podoll" 2 => "K.W. Finkel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3810/hp.2014.10.1139" "Revista" => array:7 [ "tituloSerie" => "Hosp Pract (1995)" "fecha" => "2014" "volumen" => "42" "numero" => "1" "paginaInicial" => "7" "paginaFinal" => "14" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25502126" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute kidney injury: epidemiology, outcomes, complications, and therapeutic strategies" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Negi" 1 => "D. Koreeda" 2 => "S. Kobayashi" 3 => "T. Yano" 4 => "K. Tatsuta" 5 => "T. Mima" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/sdi.12705" "Revista" => array:7 [ "tituloSerie" => "Semin Dial [Internet]" "fecha" => "2018" "volumen" => "31" "numero" => "5" "paginaInicial" => "519" "paginaFinal" => "527" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29738093" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The incidence of acute kidney injury and associated hospital mortality" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D. Khadzhynov" 1 => "D. Schmidt" 2 => "J. Hardt" 3 => "G. Rauch" 4 => "P. Gocke" 5 => "K.U. Eckardt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3238/arztebl.2019.0397" "Revista" => array:7 [ "tituloSerie" => "Dtsch Arztebl Int." "fecha" => "2019" "volumen" => "116" "numero" => "22" "paginaInicial" => "397" "paginaFinal" => "404" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31366430" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endocarditis due to rare and fastidious bacteria" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Brouqui" 1 => "D. Raoult" ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1128/CMR.14.1.177-207.2001" "Revista" => array:7 [ "tituloSerie" => "Clin Microbiol Rev [Internet]" "fecha" => "2001" "volumen" => "14" "numero" => "1" "paginaInicial" => "177" "paginaFinal" => "207" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11148009" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1128/CMR.14.1.177-207.2001" "WWW" => array:1 [ "link" => "https://cmr.asm.org/content/14/1/177" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis of 22 new cases of bartonella endocarditis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Raoult" ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.7326/0003-4819-125-8-199610150-00004" "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med [Internet]" "fecha" => "1996" "volumen" => "125" "numero" => "8" "paginaInicial" => "646" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8849149" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.7326/0003-4819-125-8-199610150-00004" "WWW" => array:1 [ "link" => "http://annals.org/article.aspx?doi=10.7326/0003-4819-125-8-199610150-00004" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Do we care if you have a cat? Bartonella infection related glomerulonephritis with no endocarditis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Singhania" 1 => "N. Singhania" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Infez Med." "fecha" => "2019" "volumen" => "27" "numero" => "4" "paginaInicial" => "441" "paginaFinal" => "444" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31846996" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bartonella endocarditis and pauci-immune glomerulonephritis: a case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.E. Raybould" 1 => "A.L. Raybould" 2 => "M.K. Morales" 3 => "M. Zaheer" 4 => "M.S. Lipkowitz" 5 => "J.G. Timpone" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Dis Clin Pract." "fecha" => "2016" "volumen" => "24" "numero" => "5" "paginaInicial" => "254" "paginaFinal" => "260" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "B artonella endocarditis masquerading as systemic vasculitis with rapidly progressive glomerulonephritis (aka Löhlein nephritis’)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L. Bannon" 1 => "G. Choshen" 2 => "M. Giladi" 3 => "J. Ablin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "BMJ Case Rep." "fecha" => "2019" "volumen" => "12" "numero" => "12" "paginaInicial" => "10" "paginaFinal" => "13" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic bartonellosis manifesting with endocarditis and membranoproliferative glomerulonephritis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Shaikh" 1 => "E.O. Gosmanova" 2 => "N. Rigual-Soler" 3 => "P. Der Mesropian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "J Investig Med High Impact Case Reports." "fecha" => "2020" "volumen" => "8" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/20132514/0000004400000002/v2_202410292119/S2013251424000798/v2_202410292119/en/main.assets" "Apartado" => array:4 [ "identificador" => "35436" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/20132514/0000004400000002/v2_202410292119/S2013251424000798/v2_202410292119/en/main.pdf?idApp=UINPBA000064&text.app=https://revistanefrologia.com/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2013251424000798?idApp=UINPBA000064" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 October | 64 | 44 | 108 |
| 2024 September | 71 | 48 | 119 |
| 2024 August | 72 | 81 | 153 |
| 2024 July | 55 | 22 | 77 |
| 2024 June | 116 | 90 | 206 |
| 2024 May | 140 | 117 | 257 |
| 2024 April | 84 | 51 | 135 |
