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"Carballo-Alvarez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Aparato Digestivo, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Nefrología, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Enteropatía pierde-proteínas en un paciente en diálisis peritoneal" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 875 "Ancho" => 1976 "Tamanyo" => 200138 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Endoscopic evaluation using videocapsule showing diffuse thickening of intestinal folds, intense lymphangiectasia and a nodular mucosa with multiple ulcers.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">There are several nutritional abnormalities in the peritoneal dialysis patient (PD).<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a> But there are not recommendations from clinical guidelines<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">2,3</span></a> or systematic reviews<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a> regarding enteropathies as the cause on malabsorption and malnutrition in these patients.</p><p id="par0010" class="elsevierStylePara elsevierViewall">We present a patient, 49 years old on PD because IgM nephropathy, with severe diarrhea with hypoalbuminemia and progressive weight loss.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Endoscopies and intestinal transit with barium were normal. Abdominal computer tomography revealed mesenteric adenopathies although the biopsy showed reactive lymphoid tissue without evidence of malignancy.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Clinically, the patient progressively deteriorated with signs of marked malnutrition and requiring regular blood transfusion to control the anemia. Then it was decide to perform an endoscopy of small intestine using a video capsule. It was observed a diffuse thickening of the intestinal wall with lymphangiectasia wide areas of ulcers, narrowing and bleeding spots (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a and 1b). Next, biopsies were obtained that were informed as non-specific inflammation and lymphangiectasia. A new endoscopy with biopsies led to similar results.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">The diagnosis was entheropathy related to PD, and the patient was transferred to hemodialysis. During the following weeks, the patient improved significantly, gained weight and did not require additional blood transfusions. Six months later an additional endoscopy revealed significant healing of the intestinal mucosa. Presently the patient is in the waiting list for renal transplantation.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Enteropathy causing loss of protein in PD patients is infrequent and it is not well recognized. There are only few reports in the literature.<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">5,6</span></a> The pathophysiological theory is that long term changes in the peritoneal membrane could result in obstruction of the lymphatic drainage; the lymphangiectasia would be the main responsible for the protein losing enteropathy.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">7</span></a> The treatment would be switching to hemodialysis.</p><p id="par0035" class="elsevierStylePara elsevierViewall">In our case there were severe clinical consequences that forced multiple exploratory intervention among other the enteroscopy with viedeocapsule using the technique of double balloon. It is likely that this type of entheropathy may play a role in the suboptimal nutritional status of some PD patients. So it should be suspected if biochemistry is altered even if the patient is asymptomatic. We suggest to perform endoscopy with videocapsule in PD patients with hypoalbuminemia, anemia and unjustified weight loss.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Egea-Valenzuela J, Martinez-Losa A, Alajarin-Cervera M, Lanuza-Luengo M, Alberca-de-las-Parras F, Carballo-Alvarez F. Enteropatía pierde-proteínas en un paciente en diálisis peritoneal. Nefrologia.2017;37:223–224.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 875 "Ancho" => 1976 "Tamanyo" => 200138 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Endoscopic evaluation using videocapsule showing diffuse thickening of intestinal folds, intense lymphangiectasia and a nodular mucosa with multiple ulcers.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0040" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in nutritional status on follow-up of an incident cohort of continuous ambulatory peritoneal dialysis patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "N. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 7 | 13 |
2024 October | 53 | 44 | 97 |
2024 September | 57 | 35 | 92 |
2024 August | 81 | 61 | 142 |
2024 July | 42 | 31 | 73 |
2024 June | 47 | 30 | 77 |
2024 May | 59 | 47 | 106 |
2024 April | 46 | 60 | 106 |
2024 March | 37 | 28 | 65 |
2024 February | 32 | 36 | 68 |
2024 January | 41 | 35 | 76 |
2023 December | 30 | 34 | 64 |
2023 November | 45 | 39 | 84 |
2023 October | 47 | 35 | 82 |
2023 September | 53 | 31 | 84 |
2023 August | 50 | 34 | 84 |
2023 July | 57 | 39 | 96 |
2023 June | 35 | 27 | 62 |
2023 May | 51 | 35 | 86 |
2023 April | 36 | 19 | 55 |
2023 March | 74 | 23 | 97 |
2023 February | 45 | 21 | 66 |
2023 January | 54 | 31 | 85 |
2022 December | 56 | 25 | 81 |
2022 November | 46 | 29 | 75 |
2022 October | 69 | 35 | 104 |
2022 September | 50 | 29 | 79 |
2022 August | 31 | 39 | 70 |
2022 July | 61 | 42 | 103 |
2022 June | 68 | 38 | 106 |
2022 May | 38 | 34 | 72 |
2022 April | 42 | 56 | 98 |
2022 March | 32 | 41 | 73 |
2022 February | 58 | 44 | 102 |
2022 January | 64 | 32 | 96 |
2021 December | 44 | 36 | 80 |
2021 November | 49 | 39 | 88 |
2021 October | 173 | 41 | 214 |
2021 September | 61 | 37 | 98 |
2021 August | 105 | 47 | 152 |
2021 July | 52 | 39 | 91 |
2021 June | 44 | 35 | 79 |
2021 May | 66 | 44 | 110 |
2021 April | 111 | 56 | 167 |
2021 March | 76 | 47 | 123 |
2021 February | 66 | 32 | 98 |
2021 January | 48 | 20 | 68 |
2020 December | 23 | 19 | 42 |
2020 November | 27 | 20 | 47 |
2020 October | 34 | 23 | 57 |
2020 September | 28 | 19 | 47 |
2020 August | 22 | 16 | 38 |
2020 July | 36 | 13 | 49 |
2020 June | 38 | 9 | 47 |
2020 May | 31 | 19 | 50 |
2020 April | 21 | 24 | 45 |
2020 March | 16 | 12 | 28 |
2020 February | 32 | 26 | 58 |
2020 January | 35 | 22 | 57 |
2019 December | 25 | 33 | 58 |
2019 November | 14 | 20 | 34 |
2019 October | 22 | 11 | 33 |
2019 September | 21 | 15 | 36 |
2019 August | 18 | 17 | 35 |
2019 July | 23 | 23 | 46 |
2019 June | 25 | 15 | 40 |
2019 May | 37 | 23 | 60 |
2019 April | 87 | 27 | 114 |
2019 March | 44 | 17 | 61 |
2019 February | 22 | 12 | 34 |
2019 January | 31 | 19 | 50 |
2018 December | 177 | 48 | 225 |
2018 November | 298 | 28 | 326 |
2018 October | 319 | 30 | 349 |
2018 September | 96 | 17 | 113 |
2018 August | 70 | 16 | 86 |
2018 July | 59 | 11 | 70 |
2018 June | 90 | 13 | 103 |
2018 May | 100 | 17 | 117 |
2018 April | 129 | 10 | 139 |
2018 March | 126 | 9 | 135 |
2018 February | 109 | 7 | 116 |
2018 January | 71 | 5 | 76 |
2017 December | 98 | 7 | 105 |
2017 November | 69 | 15 | 84 |
2017 October | 36 | 7 | 43 |
2017 September | 69 | 4 | 73 |
2017 August | 91 | 2 | 93 |
2017 July | 65 | 9 | 74 |
2017 June | 74 | 27 | 101 |
2017 May | 67 | 10 | 77 |
2017 April | 55 | 16 | 71 |