Original investigation: dialysis therapiesAssociation of depression with malnutrition in chronic hemodialysis patients
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Patient characteristics
This study enrolled all patients with chronic renal failure who were free of acute illness within the past 3 months, not administered corticosteroids, and on dialysis therapy for more than 6 months at the outpatient hemodialysis unit of Hallym University Hospital (Chunchon, Korea). Of 76 eligible patients, 14 patients who were uncooperative with this study or refused to answer the depression scale inventory were excluded. Sixty-two patients completed the cross-sectional study. Causes of chronic
Results
Principal clinical data and nutritional status of patients are listed in Table 1. Mean total BDI score was 22.7 ± 11.4, which falls in the range of moderate to severe depression using criteria for the Western population. Thirty-five patients (56.5%) had a BDI score higher than 21, which is the cutoff score for the diagnosis of depression for the Korean population.
There was a significant correlation between age and severity of depression (BDI score, r = 0.45; P < 0.001; CDI score, r = 0.39; P <
Discussion
This study showed a high incidence of depression and positive correlations between severity of depressive symptoms and degree of malnutrition in chronic hemodialysis patients. Multiple regression analysis also identified severity of depression as an independent determinant for a variety of nutritional parameters. This relation might simply reflect a psychological response to a worse overall medical condition.
However, depression commonly is associated with poor oral intake, which can aggravate
Acknowledgements
The authors thank Eun-Young Noh, RN, and Seung-Nam Cho, RN, of Hallym University Hospital for their assistance with the study.
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Supported by a Research Grant from Hallym University, Korea.