Renal transplantationPre-transplant candidatePulmonary Function in Renal Transplant Recipients and End-Stage Renal Disease Patients Undergoing Maintenance Dialysis
Section snippets
Methods
The study involved 73 subjects, including 49 CRF patients who were either on CAPD (n = 22) or HD (n = 27) treatment, and a group of renal transplant (RT) recipients (n = 24) being followed by Baskent University Hospital, Ankara, Turkey. All were being regularly assessed in our institution’s Transplantation Department. The exclusion criteria were chronic disease of the lung or chest wall, current or previous smoking habit, and signs of hypervolemia. All patients were ambulatory and in stable
Results
Table 1 shows the demographic data for the three study groups. There were no significant differences among the groups with respect to age, sex, and etiology for CRF distribution. The mean duration of dialysis was significantly longer in the HD group than in the CAPD group. The mean time since transplantation in the RT group was 46.0 ± 41.6 months (range, 3 to 174 months).
The 24 patients in the RT group were on immunosuppressive protocols that included at least two drugs. All were using
Discussion
This investigation assessed pulmonary function in RT patients and patients on CAPD and HD. Comparison revealed that the HD group had the highest frequency of radiological pathology on chest X-ray (92.5%). Although this rate was highest in the HD group, patients in the CAPD group also had high frequencies of radiological findings and PFT interpretations (restrictive-type disorders) consistent with pulmonary venous congestion. The relatively high proportion of HD patients with hyponatremia (8/27
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