Journal of Biological Chemistry
Volume 298, Issue 7, July 2022, 102010
Research ArticleFollistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo
Under a Creative Commons license
open access
Keywords
FSTL1
Wnt
FZD
β-catenin
kidney fibrosis
Abbreviations
α-SMA
alpha-smooth muscle actin
AKI
acute kidney injury
BMP
bone morphogenetic protein
CaMKII
Ca2+/calmodulin–dependent protein kinase II
CKD
chronic kidney disease
DMEM
Dulbecco's modified Eagle's medium
EC
extracellular calcium–binding domain
FBS
fetal bovine serum
Fn
fibronectin
FS
follistatin
FSTL1
follistatin-like 1
FSTL3
follistatin-like 3
FZD
Frizzled
HA
hemagglutinin
HEK293T
human embryonic kidney 293T cell line
IMCD3
inner medullary collecting duct 3
IP
immunoprecipitation
JNK
c-Jun N-terminal kinase
LRP
low-density lipoprotein receptor–related protein
MESD
mesoderm development LRP chaperone
NRK-49F
normal rat kidney 49 fibroblast cell
PDGFRβ
platelet-derived growth factor receptor beta
SNAP-FZD4
SNAP-tagged FZD4
SPARC
secreted protein, acidic and rich in cysteine
TGF-β
transforming growth factor beta
UUO
unilateral ureteral obstruction
VWC
von Willebrand factor type C–like
YAP
Yes-associated protein
Cited by (0)
© 2022 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.