Clinical ResearchBiomarkersRenal Clearance of B-Type Natriuretic Peptide and Amino Terminal Pro-B-Type Natriuretic Peptide: A Mechanistic Study in Hypertensive Subjects
Biomarkers
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Key Words
natriuretic peptides
NT-proBNP
BNP
kidney
renal function
Abbreviations and Acronyms
BNP
B-type natriuretic peptide
CKD
chronic kidney disease
FE
fractional extraction
GFR
glomerular filtration rate
IQR
interquartile range
MAP
mean arterial pressure
NT-proBNP
amino terminal pro-B-type natriuretic peptide
RBF
renal blood flow
RPF
renal plasma flow
SMWP
small molecular weight protein
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Roche Diagnostics supplied NT-proBNP reagents for this study. Dr. van Kimmenade is sponsored by a research fellowship grant from the Interuniversity Cardiology Institute of the Netherlands (ICIN). Dr. Januzzi is supported in part by the Balson Scholar fund; and has received grant funding, consulting income, and/or speaking honoraria from Roche Diagnostics, Siemens, Inverness Medical, and Critical Diagnostics. Dr. Pinto has received grant funding and speaking honoraria from Roche Diagnostics.
Copyright © 2009 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.