Comparison of estimated glomerular filtration rate with estimated creatinine clearance in the dosing of drugs requiring adjustments in elderly patients with declining renal function
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Drug Utilization Evaluation (DUE) of vancomycin: A cross-sectional study
2022, Annals of Medicine and SurgeryCitation Excerpt :In evaluation of vancomycin use in university-affiliated hospitals in Southern Khorasan Province (East Iran) based on HICPAC guidelines it was shown that only 10.6% of the patients showed inappropriate vancomycin use according to the HICPAC criteria [19]. Creatinine clearance is a relatively good estimate for renal dose adjustment; therefore, daily monitoring of serum creatinine and estimation of creatinine clearance, in addition to ensuring the appropriate dose of the drug, can be effective in preventing renal toxicity [20–22]. The difference between the renal toxicities of vancomycin may be due to the different criteria used to define renal toxicity, different study populations, and concomitant administration of nephrotoxic agents.
Drug dosing in cancer patients with decreased kidney function: A practical approach
2021, Cancer Treatment ReviewsCitation Excerpt :In general, there is an urgent need for additional studies investigating the validity of currently used estimates of kidney function in cancer patients and their applicability to traditional anticancer dosing. To date, most studies have compared the different formulas with each other in hypothetical simulations and not with actual drug clearance [90–97]. Future studies should ideally include therapeutic drug monitoring and clinical outcomes to establish the optimal dose for cancer patients with different degrees of kidney dysfunction.
Kidney function
2019, Onco-NephrologyGlomerular filtration rate estimation in people older than 85: Comparison between CKD-EPI, MDRD-IDMS and BIS1 equations
2017, NefrologiaCitation Excerpt :There reports on CKD screening in population of individuals 60–80 y.o.7–9 using equations to calculate eGFR based on serum Cr. Information about the use of these equations in individuals >85 years of age is limited; the diet, weight and body surface10 are different in elderly and younger people. The study by Gómez-Pavón et al.9 in 70 patents >75 y.o. concludes that the values of eGFR obtained by the MDRD-IDMS are not the same as eGFR corrected by body surface or the estimated by the Cockcroft–Gault equation.9
Dosing adjustment and renal function: Which equation(s)?
2016, Nephrologie et TherapeutiqueComparison of estimated glomerular filtration rate equations for dosing new oral anticoagulants in patients with atrial fibrillation
2015, Revista Espanola de Cardiologia