American Journal of Obstetrics and Gynecology
ResearchObstetricsEnd-stage renal disease after hypertensive disorders in pregnancy
Section snippets
Study population
The NHI program began in 1995 and covers 99% of Taiwan's population.20 All claims data are managed by the National Health Insurance Administration before being transferred to the National Health Research Institutes. We searched a subset of the NHI database for inpatient expenditures by admission codes to identify women who had deliveries between 1998 and 2002. The admission codes are determined by coders based on the physician-determined diagnoses that were recorded in patient charts. Patients
Results
The study population consisted of 944,474 women who, after giving birth, had been discharged from hospitals in Taiwan; of those women, 13,633 had a history of HDPs, and 930,841 did not. On average, the women with HDPs were older than those without and were more likely to have had a cesarean delivery, to have had only 1 delivery during the study period, and lived in an urban area (Table 1).
During the follow-up period, 0.34% and 0.02% of the women with and without HDPs, respectively, were
Comment
We found, in this population-based study, that HDPs were associated significantly with a higher risk of ESRD. The risk of ESRD was higher in women who gave birth at ≥35 years old. Women who previously had delivered a child after having an HDP had a lower risk of ESRD. Neither a cesarean section nor a delivery complication was a risk factor for ESRD after adjustment for age, delivery type, and number of deliveries after an HDP. Each type of HDP was associated with the risk of ESRD; women with
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Cardiovascular and renal health: Preeclampsia as a risk marker
2023, NefrologiaAdverse pregnancy outcomes and long-term risk of chronic kidney disease in women: national cohort and co-sibling study
2023, American Journal of Obstetrics and GynecologyEffect of preeclampsia and its severity on maternal serum NGAL and KIM-1 levels during pregnancy and the post-pregnancy period
2021, European Journal of Obstetrics and Gynecology and Reproductive BiologyCitation Excerpt :In line with this study results, adjustment for hypertension and other co-morbidities has reduced the estimated results; however, these hypertensive disorders have been linked to a two to three-fold increase in the risk of renal disorder later in life. Similarly, Wu et al. [31] have found that a history of hypertensive disease during pregnancy is related to a tenfold increase in the risk of end-stage kidney disorder. Preeclampsia, especially that early in the pregnancy, is also strongly related to several chronic kidney diseases later in life [32].
Pre-eclampsia is associated with later kidney chronic disease and end-stage renal disease: Systematic review and meta-analysis of observational studies
2020, Pregnancy HypertensionCitation Excerpt :Regarding ESRD in the present review, it was also observed that PE was a risk factor for ESRD, corroborating the findings of Covella et al.[16], but some points should be considered. In the present review, we included 4 more studies [13,17,26,29], presenting an heterogeneity of I2 = 88.9% while in Covella et al.[16] study, the I2 was 95%. Another aspect that could be discussed in this review, which made it difficult to compare the included research data, was the absence of a control group in some of the studies, making a better comparison with the PE group impossible, as seen in the study by Van Balen et al.[8].
Chronic hypertension in pregnancy
2020, American Journal of Obstetrics and GynecologyIs preeclampsia a risk for end-stage renal disease?
2019, Kidney International
Supported by grant number CMFHR 9964 from Chi Mei Medical Center and grant number NHRI-NHIRD-99095 from the National Health Research Institute for the database.
The authors report no conflict of interest.
Reprints not available from the authors.
Cite this article as: Wu C-C, Chen S-H, Ho C-H, et al. End-stage renal disease after hypertensive disorders in pregnancy. Am J Obstet Gynecol 2014;210:147.e1-8.